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PaperBLAST

PaperBLAST Hits for CharProtDB::CH_005143 isocitrate dehydrogenase; EC 1.1.1.42 (Bacillus subtilis) (423 a.a., MAQGEKITVS...)

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Predict protein localization: PSORTb

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Found 250 similar proteins in the literature:

IDH_BACSU / P39126 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Bacillus subtilis (strain 168) (see 2 papers)
icd / GB|CAB14873.1 isocitrate dehydrogenase; EC 1.1.1.42 from Bacillus subtilis (see 2 papers)
NP_390791 isocitrate dehydrogenase from Bacillus subtilis subsp. subtilis str. 168
100% identity, 100% coverage

GYA98_RS12235 NADP-dependent isocitrate dehydrogenase from Bacillus velezensis
95% identity, 100% coverage

YP_092619 Icd from Bacillus licheniformis DSM 13
95% identity, 96% coverage

W8Y9G2 Isocitrate dehydrogenase [NADP] from Bacillus thuringiensis DB27
BC4593 Isocitrate dehydrogenase [NADP] from Bacillus cereus ATCC 14579
86% identity, 98% coverage

BAS4487 isocitrate dehydrogenase, NADP-dependent from Bacillus anthracis str. Sterne
86% identity, 97% coverage

lmo1566 highly similar to isocitrate dehyrogenases from Listeria monocytogenes EGD-e
NP_465091 isocitrate dehydrogenase from Listeria monocytogenes EGD-e
LMRG_01401 isocitrate dehydrogenase, NADP-dependent from Listeria monocytogenes 10403S
81% identity, 99% coverage

UH47_10560 NADP-dependent isocitrate dehydrogenase from Staphylococcus pseudintermedius
80% identity, 98% coverage

N007_05885 NADP-dependent isocitrate dehydrogenase from Alicyclobacillus acidoterrestris ATCC 49025
78% identity, 98% coverage

Q5HNL1 Isocitrate dehydrogenase [NADP] from Staphylococcus epidermidis (strain ATCC 35984 / DSM 28319 / BCRC 17069 / CCUG 31568 / BM 3577 / RP62A)
Q8CNX4 Isocitrate dehydrogenase [NADP] from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
80% identity, 99% coverage

SXYL_01173 NADP-dependent isocitrate dehydrogenase from Staphylococcus xylosus
79% identity, 99% coverage

SAS1622 isocitrate dehydrogenase from Staphylococcus aureus subsp. aureus MSSA476
79% identity, 99% coverage

SAPIG1748 NADP-dependent isocitrate dehydrogenase from Staphylococcus aureus subsp. aureus ST398
79% identity, 99% coverage

SACOL1741 isocitrate dehydrogenase, NADP-dependent from Staphylococcus aureus subsp. aureus COL
P99167 Isocitrate dehydrogenase [NADP] from Staphylococcus aureus (strain N315)
Q2FXN4 Isocitrate dehydrogenase [NADP] from Staphylococcus aureus (strain NCTC 8325 / PS 47)
SA1517 isocitrate dehydrogenase from Staphylococcus aureus subsp. aureus N315
SAV1694 isocitrate dehydrogenase from Staphylococcus aureus subsp. aureus Mu50
SAOUHSC_01801 isocitrate dehydrogenase, NADP-dependent from Staphylococcus aureus subsp. aureus NCTC 8325
SAUSA300_1640 isocitrate dehydrogenase, NADP-dependent from Staphylococcus aureus subsp. aureus USA300_FPR3757
79% identity, 99% coverage

Q6GG12 Isocitrate dehydrogenase [NADP] from Staphylococcus aureus (strain MRSA252)
79% identity, 99% coverage

MXAN_3537 isocitrate dehydrogenase, NADP-dependent from Myxococcus xanthus DK 1622
69% identity, 97% coverage

Pcar_1038 isocitrate dehydrogenase, NADP-dependent from Pelobacter carbinolicus str. DSM 2380
66% identity, 90% coverage

Dgeo_1166 isocitrate/isopropylmalate dehydrogenase from Deinococcus geothermalis DSM 11300
68% identity, 99% coverage

Q9RU54 Isocitrate dehydrogenase [NADP] from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)
DR1540, DR_1540 isocitrate dehydrogenase from Deinococcus radiodurans R1
67% identity, 98% coverage

Ppro_0452 isocitrate dehydrogenase, NADP-dependent from Pelobacter propionicus DSM 2379
62% identity, 89% coverage

Q8X722 Isocitrate dehydrogenase [NADP] from Escherichia coli O157:H7
67% identity, 100% coverage

IcdE / b1136 isocitrate dehydrogenase (EC 1.1.1.42) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
icd / P08200 isocitrate dehydrogenase (EC 1.1.1.42) from Escherichia coli (strain K12) (see 3 papers)
IDH_ECOLI / P08200 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-dependent isocitric dehydrogenase; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Escherichia coli (strain K12) (see 9 papers)
P08200 [Isocitrate dehydrogenase (NADP+)] kinase (EC 2.7.11.5) from Escherichia coli (see paper)
4aj3A / P08200 3d structure of e. Coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and NADP - the pseudo-michaelis complex (see paper)
NP_415654 isocitrate dehydrogenase from Escherichia coli str. K-12 substr. MG1655
b1136 isocitrate dehydrogenase from Escherichia coli str. K-12 substr. MG1655
Y75_p1106 NADP-dependent isocitrate dehydrogenase from Escherichia coli str. K-12 substr. W3110
67% identity, 100% coverage

SF1155 isocitrate dehydrogenase from Shigella flexneri 2a str. 301
UTI89_C1266 NADP Isocitrate dehydrogenase from Escherichia coli UTI89
S1238 isocitrate dehydrogenase from Shigella flexneri 2a str. 2457T
67% identity, 100% coverage

Entcl_2658 NADP-dependent isocitrate dehydrogenase from [Enterobacter] lignolyticus SCF1
68% identity, 100% coverage

A6T7K6 Isocitrate dehydrogenase [NADP] from Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
67% identity, 100% coverage

KPK_3407 isocitrate dehydrogenase, NADP-dependent from Klebsiella pneumoniae 342
66% identity, 100% coverage

STY1278 isocitrate dehydrogenase from Salmonella enterica subsp. enterica serovar Typhi str. CT18
67% identity, 99% coverage

SPC_2506 isocitrate dehydrogenase from Salmonella enterica subsp. enterica serovar Paratyphi C strain RKS4594
66% identity, 99% coverage

STM1238 isocitrate dehydrogenase in e14 prophage, specific for NADP+ from Salmonella typhimurium LT2
66% identity, 99% coverage

JHW33_RS08805 NADP-dependent isocitrate dehydrogenase from Rahnella aceris
66% identity, 100% coverage

PMI0891 isocitrate dehydrogenase [NADP] from Proteus mirabilis HI4320
67% identity, 100% coverage

CtesDRAFT_PD1824 NADP-dependent isocitrate dehydrogenase from Comamonas testosteroni KF-1
66% identity, 100% coverage

H16_A3056 NADP-dependent isocitrate dehydrogenase from Cupriavidus necator H16
H16_A3056 isocitrate dehydrogenase [NADP] from Ralstonia eutropha H16
65% identity, 99% coverage

Rmet_2895 NADP-dependent isocitrate dehydrogenase from Cupriavidus metallidurans CH34
Rmet_2895 isocitrate dehydrogenase, NADP-dependent from Ralstonia metallidurans CH34
65% identity, 99% coverage

CBU_1200 isocitrate dehydrogenase from Coxiella burnetii RSA 493
66% identity, 98% coverage

IDH_COXBU / Q9ZH99 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Coxiella burnetii (strain RSA 493 / Nine Mile phase I) (see 2 papers)
66% identity, 99% coverage

VAS14_05433 NADP-dependent isocitrate dehydrogenase from Photobacterium angustum S14
64% identity, 99% coverage

ZMO0544 isocitrate dehydrogenase, NADP-dependent from Zymomonas mobilis subsp. mobilis ZM4
61% identity, 99% coverage

y1802 isocitrate dehydrogenase, specific for NADP+ from Yersinia pestis KIM
65% identity, 97% coverage

YPO1641 isocitrate dehydrogenase [NADP] from Yersinia pestis CO92
YPTB2427 isocitrate dehydrogenase [NADP] from Yersinia pseudotuberculosis IP 32953
65% identity, 100% coverage

Q3JV82 Isocitrate dehydrogenase [NADP] from Burkholderia pseudomallei (strain 1710b)
BURPS1710b_1108 isocitrate dehydrogenase, NADP-dependent from Burkholderia pseudomallei 1710b
BPSL0896 isocitrate dehydrogenase from Burkholderia pseudomallei K96243
65% identity, 99% coverage

D0Z8Y6 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Edwardsiella tarda (see paper)
ETAE_2050 isocitrate dehydrogenase, specific for NADP+ from Edwardsiella tarda EIB202
65% identity, 99% coverage

BCAL2736 isocitrate dehydrogenase from Burkholderia cenocepacia J2315
65% identity, 99% coverage

E2566_10015 NADP-dependent isocitrate dehydrogenase from Pectobacterium punjabense
65% identity, 99% coverage

RSc2490 PROBABLE ISOCITRATE DEHYDROGENASE [NADP] OXIDOREDUCTASE PROTEIN from Ralstonia solanacearum GMI1000
65% identity, 99% coverage

Q2T0I4 Isocitrate dehydrogenase [NADP] from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CCUG 48851 / CIP 106301 / E264)
BTH_I0759 isocitrate dehydrogenase, NADP-dependent from Burkholderia thailandensis E264
65% identity, 99% coverage

RSUY_RS12515 NADP-dependent isocitrate dehydrogenase from Ralstonia solanacearum
64% identity, 99% coverage

EDI29_02475 NADP-dependent isocitrate dehydrogenase from Pectobacterium polonicum
65% identity, 99% coverage

BP2488 isocitrate dehydrogenase [NADP] from Bordetella pertussis Tohama I
64% identity, 99% coverage

Q1XIQ8 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Colwellia psychrerythraea (see paper)
64% identity, 99% coverage

jhp0023 ISOCITRATE DEHYDROGENASE from Helicobacter pylori J99
Q9ZN36 Isocitrate dehydrogenase [NADP] from Helicobacter pylori (strain J99 / ATCC 700824)
63% identity, 99% coverage

IDH_PSEAB / Q02NB5 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
Q9I0L5 Isocitrate dehydrogenase [NADP] from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
NP_251313 isocitrate dehydrogenase from Pseudomonas aeruginosa PAO1
PA14_30190 isocitrate dehydrogenase from Pseudomonas aeruginosa UCBPP-PA14
PA2623 isocitrate dehydrogenase from Pseudomonas aeruginosa PAO1
63% identity, 100% coverage

P56063 Isocitrate dehydrogenase [NADP] from Helicobacter pylori (strain ATCC 700392 / 26695)
HP0027 isocitrate dehydrogenase (icd) from Helicobacter pylori 26695
63% identity, 99% coverage

icd / B2ZP83 isocitrate dehydrogenase subunit (EC 1.1.1.42) from Helicobacter pylori (see 4 papers)
62% identity, 99% coverage

LT988_17130 NADP-dependent isocitrate dehydrogenase from Thiocapsa bogorovii
63% identity, 100% coverage

HPG27_RS00150 isocitrate dehydrogenase (NADP(+)) from Helicobacter pylori G27
62% identity, 99% coverage

V6E02_11500 NADP-dependent isocitrate dehydrogenase from Thiobacter sp. AK1
64% identity, 100% coverage

Q8GAX0 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Acidithiobacillus thiooxidans (see paper)
61% identity, 98% coverage

2d4vA / Q8GAX0 Crystal structure of NAD dependent isocitrate dehydrogenase from acidithiobacillus thiooxidans (see paper)
61% identity, 99% coverage

T1E_0537 NADP-dependent isocitrate dehydrogenase from Pseudomonas putida DOT-T1E
62% identity, 99% coverage

PPUTLS46_011960 NADP-dependent isocitrate dehydrogenase from Pseudomonas putida LS46
62% identity, 99% coverage

PPUBIRD1_1803 NADP-dependent isocitrate dehydrogenase from Pseudomonas putida BIRD-1
62% identity, 99% coverage

Q5ZXB6 Isocitrate dehydrogenase [NADP] from Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
61% identity, 100% coverage

ACIAD1190 isocitrate dehydrogenase from Acinetobacter sp. ADP1
62% identity, 96% coverage

PP4011 isocitrate dehydrogenase, NADP-dependent, prokaryotic-type from Pseudomonas putida KT2440
PP_4011 NADP-dependent isocitrate dehydrogenase from Pseudomonas putida KT2440
61% identity, 99% coverage

lpp0878 isocitrate dehydrogenase from Legionella pneumophila str. Paris
61% identity, 100% coverage

6c0eA / Q5ZXB6 Crystal structure of isocitrate dehydrogenase from legionella pneumophila with bound NADPH with an alpha-ketoglutarate adduct
61% identity, 100% coverage

ABO_1282 isocitrate dehydrogenase (NADP-dependent) from Alcanivorax borkumensis SK2
62% identity, 100% coverage

AFE_RS02000 NADP-dependent isocitrate dehydrogenase from Acidithiobacillus ferrooxidans ATCC 23270
61% identity, 98% coverage

SGO_1611 Isocitrate dehydrogenase from Streptococcus gordonii str. Challis substr. CH1
60% identity, 99% coverage

E9B494 Isocitrate dehydrogenase [NADP] from Leishmania mexicana (strain MHOM/GT/2001/U1103)
58% identity, 99% coverage

PFLU3808 isocitrate dehydrogenase from Pseudomonas fluorescens SBW25
60% identity, 100% coverage

MS2370 Icd protein from Mannheimia succiniciproducens MBEL55E
MS2370 NADP-dependent isocitrate dehydrogenase from [Mannheimia] succiniciproducens MBEL55E
61% identity, 100% coverage

IDH1_COLMA / P41560 Isocitrate dehydrogenase [NADP] 1; IDH-I; IDP-1; NADP(+)-specific ICDH 1; Oxalosuccinate decarboxylase 1; EC 1.1.1.42 from Colwellia maris (see 2 papers)
icd / BAA03135.1 isocitrate dehydrogenase isozyme IDH-I from Colwellia maris (see paper)
61% identity, 99% coverage

Q59940 Isocitrate dehydrogenase [NADP] from Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
59% identity, 98% coverage

SSU1040 isocitrate dehydrogenase [NADP] from Streptococcus suis P1/7
59% identity, 99% coverage

Q1GZD1 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Methylobacillus flagellatus (see paper)
61% identity, 99% coverage

IDH1_PSYS3 / A0A5A4WIX0 Isocitrate dehydrogenase [NADP] 1; IDH 1; EC 1.1.1.42 from Psychrobacter sp. (strain 13A) (see paper)
62% identity, 99% coverage

BP951000_0369 NADP-dependent isocitrate dehydrogenase from Brachyspira pilosicoli 95/1000
60% identity, 99% coverage

BF638R_3568 NADP-dependent isocitrate dehydrogenase from Bacteroides fragilis 638R
59% identity, 97% coverage

LAF_0939 NADP-dependent isocitrate dehydrogenase from Limosilactobacillus fermentum IFO 3956
LAF_0939 isocitrate dehydrogenase from Lactobacillus fermentum IFO 3956
56% identity, 99% coverage

T303_07275 NADP-dependent isocitrate dehydrogenase from Streptococcus thermophilus ASCC 1275
60% identity, 94% coverage

A1S_2475 isocitrate dehydrogenase from Acinetobacter baumannii ATCC 17978
63% identity, 91% coverage

llmg_0637 isocitrate dehydrogenase from Lactococcus lactis subsp. cremoris MG1363
58% identity, 98% coverage

SRU_1973 isocitrate dehydrogenase, NADP-dependent from Salinibacter ruber DSM 13855
55% identity, 99% coverage

DOP62_07935 NADP-dependent isocitrate dehydrogenase from Synechococcus elongatus PCC 11801
53% identity, 89% coverage

Q31MH0 Isocitrate dehydrogenase [NADP] from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805)
Synpcc7942_1719 isocitrate dehydrogenase, NADP-dependent from Synechococcus elongatus PCC 7942
53% identity, 89% coverage

IDH_NOSS1 / P50214 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-isocitrate dehydrogenase; NADP(+)-IDH; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) (see paper)
alr1827 isocitrate dehydrogenase from Nostoc sp. PCC 7120
52% identity, 89% coverage

IDH_ARCFU / O29610 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see 2 papers)
2iv0A / O29610 Thermal stability of isocitrate dehydrogenase from archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers (see paper)
AF_0647 isocitrate dehydrogenase (NADP(+)) from Archaeoglobus fulgidus DSM 4304
56% identity, 99% coverage

SYNW0166 Isocitrate dehydrogenase from Synechococcus sp. WH 8102
52% identity, 89% coverage

A8YGS2 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Microcystis aeruginosa (see paper)
51% identity, 88% coverage

slr1289 isocitrate dehydrogenase (NADP+) from Synechocystis sp. PCC 6803
52% identity, 88% coverage

cce_3202 isocitrate dehydrogenase (NADP+) from Cyanothece sp. ATCC 51142
50% identity, 85% coverage

cce_3202 NADP-dependent isocitrate dehydrogenase from Crocosphaera subtropica ATCC 51142
50% identity, 88% coverage

PMT1935 Isocitrate dehydrogenase from Prochlorococcus marinus str. MIT 9313
50% identity, 89% coverage

sync_0214 isocitrate dehydrogenase, NADP-dependent from Synechococcus sp. CC9311
53% identity, 88% coverage

Q9HLV8 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermoplasma acidophilum (see paper)
54% identity, 97% coverage

GAH_01703 isocitrate dehydrogenase (NADP(+)) from Geoglobus ahangari
55% identity, 100% coverage

IDH_HALVD / D4GU92 Isocitrate dehydrogenase [NADP]; ICDH; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
HVO_2588 isocitrate dehydrogenase (NADP+) from Haloferax volcanii DS2
53% identity, 99% coverage

icdh / CAC80860.2 NADP-isocitrate dehydrogenase from Haloferax volcanii (see paper)
53% identity, 99% coverage

IDH_SYNY3 / P80046 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP isocitrate dehydrogenase; NADP-IDH; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa) (see 2 papers)
51% identity, 88% coverage

Q7V9S5 Isocitrate dehydrogenase [NADP] from Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)
Pro1752 Isocitrate dehydrogenases from Prochlorococcus marinus str. SS120
50% identity, 88% coverage

Dret_0439 Isocitrate dehydrogenase (NADP(+)) from Desulfohalobium retbaense DSM 5692
52% identity, 95% coverage

icd / Q5UXA4 isocitrate dehydrogenase, NADP (EC 1.1.1.42) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (see 4 papers)
53% identity, 100% coverage

Kole_1227 Isocitrate dehydrogenase (NADP(+)) from Thermotogales bacterium TBF 19.5.1
Kole_1227 isocitrate dehydrogenase (NADP(+)) from Kosmotoga olearia TBF 19.5.1
52% identity, 100% coverage

PMM1596 Isocitrate dehydrogenase from Prochlorococcus marinus sp. MED4
49% identity, 89% coverage

Q72EU1 isocitrate dehydrogenase (NADP(+)) from Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough)
53% identity, 93% coverage

Q9HNZ7 isocitrate dehydrogenase (NADP(+)) from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
52% identity, 97% coverage

ST2166 409aa long hypothetical NADP-dependent isocitrate dehydrogenase from Sulfolobus tokodaii str. 7
WP_010980246 NADP-dependent isocitrate dehydrogenase from Sulfurisphaera tokodaii str. 7
50% identity, 99% coverage

Micr_00902 NADP-dependent isocitrate dehydrogenase from Candidatus Micrarchaeum sp.
49% identity, 98% coverage

2e5mA / Q96YK6 Crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii strain 7 (see paper)
49% identity, 99% coverage

Q4J6C9 isocitrate-homoisocitrate dehydrogenase (EC 1.1.1.286) from Sulfolobus acidocaldarius (see paper)
Saci_2375 isocitrate dehydrogenase from Sulfolobus acidocaldarius DSM 639
48% identity, 99% coverage

Q9YE81 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Aeropyrum pernix (see 4 papers)
48% identity, 97% coverage

1tyoA / Q9YE81 Isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in complex with etheno-NADP (see paper)
48% identity, 98% coverage

SSO2182 Isocitrate dehydrogenase, probable (idh) from Sulfolobus solfataricus P2
47% identity, 99% coverage

IDH_CALNO / P96318 Isocitrate dehydrogenase [NADP]; ICDH; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Caldococcus noboribetus (see paper)
P96318 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Caldococcus noboribetus (see 2 papers)
49% identity, 97% coverage

Q8U488 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Pyrococcus furiosus (see 2 papers)
PF0202 isocitrate dehydrogenase from Pyrococcus furiosus DSM 3638
49% identity, 100% coverage

Tneu_0698 isocitrate dehydrogenase, NADP-dependent from Thermoproteus neutrophilus V24Sta
46% identity, 94% coverage

O67480 Isocitrate dehydrogenase [NADP] from Aquifex aeolicus (strain VF5)
aq_1512 isocitrate dehydrogenase from Aquifex aeolicus VF5
46% identity, 96% coverage

icd / Q76LM6 oxalosuccinate reductase subunit from Hydrogenobacter thermophilus (see 3 papers)
45% identity, 91% coverage

DhcVS_392, GY50_0375 isocitrate/isopropylmalate dehydrogenase family protein from Dehalococcoides mccartyi VS
42% identity, 95% coverage

DehalGT_0391 Isocitrate dehydrogenase (NAD(+)) from Dehalococcoides sp. GT
cbdbA408 isocitrate/isopropylmalate dehydrogenase family protein from Dehalococcoides mccartyi CBDB1
42% identity, 95% coverage

DET0450 isocitrate dehydrogenase, putative from Dehalococcoides ethenogenes 195
41% identity, 95% coverage

dcmb_461 isocitrate/isopropylmalate dehydrogenase family protein from Dehalococcoides mccartyi DCMB5
41% identity, 95% coverage

btf_415 isocitrate/isopropylmalate dehydrogenase family protein from Dehalococcoides mccartyi BTF08
41% identity, 95% coverage

Mal48_24210 isocitrate/isopropylmalate dehydrogenase family protein from Thalassoglobus polymorphus
41% identity, 95% coverage

Mal4_26830 isocitrate/isopropylmalate dehydrogenase family protein from Maioricimonas rarisocia
40% identity, 95% coverage

ELEN_RS11715 isocitrate/isopropylmalate dehydrogenase family protein from Eggerthella lenta DSM 2243
40% identity, 94% coverage

Pan258_54730 isocitrate/isopropylmalate dehydrogenase family protein from Symmachiella dynata
39% identity, 95% coverage

CA54_25060 isocitrate/isopropylmalate dehydrogenase family protein from Symmachiella macrocystis
39% identity, 95% coverage

Mal52_56040 isocitrate/isopropylmalate dehydrogenase family protein from Symmachiella dynata
39% identity, 95% coverage

Csac_0751 Isocitrate dehydrogenase (NAD(+)) from Caldicellulosiruptor saccharolyticus DSM 8903
38% identity, 95% coverage

Clocel_2469 isocitrate/isopropylmalate dehydrogenase family protein from Clostridium cellulovorans 743B
38% identity, 95% coverage

CAC0972 Isocitrate dehydrogenase from Clostridium acetobutylicum ATCC 824
CA_C0972 isocitrate dehydrogenase (NAD(+)) from Clostridium acetobutylicum ATCC 824
37% identity, 96% coverage

CAETHG_2753 isocitrate/isopropylmalate dehydrogenase family protein from Clostridium autoethanogenum DSM 10061
35% identity, 87% coverage

CLJU_c06630 isocitrate/isopropylmalate dehydrogenase family protein from Clostridium ljungdahlii DSM 13528
34% identity, 87% coverage

6lkyA / Q602J2 Crystal structure of isocitrate dehydrogenase from methylococcus capsulatus
38% identity, 90% coverage

Q18A33 Isocitrate dehydrogenase NAD-dependent from Clostridioides difficile (strain 630)
CD0834 putative isocitrate/3-isopropylmalate dehydrogenase from Clostridium difficile 630
37% identity, 94% coverage

GOX1336 Isocitrate dehydrogenase [NADP] from Gluconobacter oxydans 621H
34% identity, 87% coverage

TTC1172 No description from Thermus thermophilus HB27
35% identity, 81% coverage

2d1cA / P33197 Crystal structure of tt0538 protein from thermus thermophilus hb8
35% identity, 81% coverage

P33197 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermus thermophilus (see 2 papers)
icd / RF|YP_144801.1 isocitrate dehydrogenase (NADP(+)); EC 1.1.1.42 from Thermus thermophilus HB8 (see 2 papers)
TTHA1535 isocitrate dehydrogenase from Thermus thermophilus HB8
35% identity, 81% coverage

ABO_0296 isocitrate dehydrogenase from Alcanivorax borkumensis SK2
33% identity, 96% coverage

APA386B_2558 isocitrate/isopropylmalate dehydrogenase family protein from Acetobacter pasteurianus 386B
34% identity, 88% coverage

XF2596 isocitrate dehydrogenase from Xylella fastidiosa 9a5c
WP_010895014 isocitrate dehydrogenase from Xylella fastidiosa 9a5c
34% identity, 88% coverage

6m3sB / A0A0H2XBX7 Dimeric isocitrate dehydrogenase from xanthomonas campestris pv. Campestris 8004
35% identity, 88% coverage

XAC1046 isocitrate dehydrogenase from Xanthomonas axonopodis pv. citri str. 306
XAUB_41080 isocitrate dehydrogenase from Xanthomonas citri pv. aurantifolii str. ICPB 11122
35% identity, 88% coverage

SO1538 isocitrate dehydrogenase, NAD-dependent from Shewanella oneidensis MR-1
34% identity, 87% coverage

AL01_06250 isocitrate/isopropylmalate dehydrogenase family protein from Bombella intestini
33% identity, 95% coverage

IDH-V / Q945K7 NAD+-dependent isocitrate dehydrogenase catalytic subunit (EC 1.1.1.286) from Arabidopsis thaliana (see 3 papers)
IDH5_ARATH / Q945K7 Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial; IDH-V; Isocitric dehydrogenase 5; NAD(+)-specific ICDH 5; EC 1.1.1.41 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q945K7 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
NP_568113 isocitrate dehydrogenase V from Arabidopsis thaliana
AT5G03290 isocitrate dehydrogenase, putative / NAD+ isocitrate dehydrogenase, putative from Arabidopsis thaliana
33% identity, 86% coverage

CG32026 uncharacterized protein from Drosophila melanogaster
32% identity, 56% coverage

Q9VWH4 Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial from Drosophila melanogaster
32% identity, 95% coverage

NP_728257 isocitrate dehydrogenase 3a, isoform C from Drosophila melanogaster
32% identity, 95% coverage

P29696 3-isopropylmalate dehydrogenase, chloroplastic from Solanum tuberosum
32% identity, 87% coverage

Q55BI2 Isocitrate dehydrogenase [NAD] regulatory subunit A, mitochondrial from Dictyostelium discoideum
31% identity, 95% coverage

IDH6_ARATH / Q8LG77 Isocitrate dehydrogenase [NAD] catalytic subunit 6, mitochondrial; IDH-VI; Isocitric dehydrogenase 6; NAD(+)-specific ICDH 6; EC 1.1.1.41 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8LG77 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see paper)
AT3G09810 isocitrate dehydrogenase, putative / NAD+ isocitrate dehydrogenase, putative from Arabidopsis thaliana
32% identity, 92% coverage

Rfer_2411 Isocitrate dehydrogenase (NAD+) from Rhodoferax ferrireducens DSM 15236
33% identity, 91% coverage

M1CHE3 3-isopropylmalate dehydrogenase, chloroplastic from Solanum tuberosum
32% identity, 86% coverage

B6TJM1 3-isopropylmalate dehydrogenase from Zea mays
31% identity, 87% coverage

Rfer_2380 Isocitrate dehydrogenase (NAD+) from Rhodoferax ferrireducens DSM 15236
34% identity, 89% coverage

LOC103934973 isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial from Pyrus x bretschneideri
31% identity, 90% coverage

TERG_07814 isocitrate dehydrogenase, NAD-dependent from Trichophyton rubrum CBS 118892
31% identity, 99% coverage

LIC13328 isocitrate dehydrogenase from Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
Q72M63 Isocitrate dehydrogenase [NADP] from Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
33% identity, 81% coverage

Afu1g12800 isocitrate dehydrogenase, NAD-dependent from Aspergillus fumigatus Af293
32% identity, 95% coverage

PAAG_07729 isocitrate dehydrogenase subunit 2 from Paracoccidioides lutzii Pb01
32% identity, 87% coverage

PADG_02805 isocitrate dehydrogenase [NAD] subunit 2, mitochondrial from Paracoccidioides brasiliensis Pb18
C1G6K0 isocitrate dehydrogenase (NAD(+)) from Paracoccidioides brasiliensis (strain Pb18)
32% identity, 87% coverage

Q28480 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (Fragment) from Macaca fascicularis
30% identity, 95% coverage

IDH3A_BOVIN / P41563 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitrate dehydrogenase subunits 3/4; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Bos taurus (Bovine) (see paper)
30% identity, 95% coverage

An08g05580 uncharacterized protein from Aspergillus niger
30% identity, 96% coverage

U3I2P1 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Anas platyrhynchos platyrhynchos
30% identity, 95% coverage

G3H0B5 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Cricetulus griseus
30% identity, 95% coverage

6kdeA / P50213 Crystal structure of the alpha beta heterodimer of human idh3 in complex with ca(2+) (see paper)
30% identity, 95% coverage

IDH3A_PIG / P56471 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Sus scrofa (Pig) (see paper)
30% identity, 95% coverage

MJ0720 / Q58130 3-isopropylmalate dehydrogenase subunit (EC 1.1.1.85) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 2 papers)
LEU3_METJA / Q58130 3-isopropylmalate/3-methylmalate dehydrogenase; 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; IPMDH; Beta-IPM dehydrogenase; D-malate dehydrogenase [decarboxylating]; EC 1.1.1.85; EC 1.1.1.n5; EC 1.1.1.83 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
MJ0720 3-isopropylmalate dehydrogenase 1 (leuB1) from Methanocaldococcus jannaschii DSM 2661
35% identity, 89% coverage

IDH3A_MOUSE / Q9D6R2 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Mus musculus (Mouse) (see paper)
Q9D6R2 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Mus musculus (see paper)
NP_083849 isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor from Mus musculus
30% identity, 95% coverage

IDH3A / P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (EC 1.1.1.286) from Homo sapiens (see 2 papers)
IDH3A_HUMAN / P50213 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Homo sapiens (Human) (see 5 papers)
P50213 isocitrate dehydrogenase (NAD+) (subunit 2/2) (EC 1.1.1.41) from Homo sapiens (see paper)
30% identity, 95% coverage

G1TA59 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Oryctolagus cuniculus
30% identity, 88% coverage

D2VQ70 Isocitrate dehydrogenase from Naegleria gruberi
32% identity, 94% coverage

Q53GF8 Isocitrate dehydrogenase [NAD] subunit, mitochondrial (Fragment) from Homo sapiens
30% identity, 95% coverage

AO090012000629 No description from Aspergillus oryzae RIB40
31% identity, 95% coverage

IDH2 / P28241 isocitrate dehydrogenase [NAD] β subunit (EC 1.1.1.286) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
IDH2_YEAST / P28241 Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P28241 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Saccharomyces cerevisiae (see paper)
NP_014779 isocitrate dehydrogenase (NAD(+)) IDH2 from Saccharomyces cerevisiae S288C
YOR136W Idh2p from Saccharomyces cerevisiae
31% identity, 95% coverage

F1LNF7 Isocitrate dehydrogenase [NAD] subunit, mitochondrial from Rattus norvegicus
30% identity, 95% coverage

NP_446090 isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor from Rattus norvegicus
30% identity, 95% coverage

FAD_1632 isocitrate/isopropylmalate family dehydrogenase from Ferroplasma acidiphilum
28% identity, 99% coverage

A0A0D1E633 isocitrate dehydrogenase (NAD(+)) from Ustilago maydis (strain 521 / FGSC 9021)
31% identity, 89% coverage

IDH3A_CAEEL / Q93714 Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Caenorhabditis elegans (see paper)
NP_492330 putative isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial from Caenorhabditis elegans
31% identity, 87% coverage

IDH2_SCHPO / Q9USP8 Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 3 papers)
30% identity, 90% coverage

idh2 / RF|NP_595203.1 isocitrate dehydrogenase (NAD+) subunit 2; EC 1.1.1.41 from Schizosaccharomyces pombe (see 2 papers)
SPBC902.05c isocitrate dehydrogenase (NAD+) subunit 2 from Schizosaccharomyces pombe
30% identity, 90% coverage

IDH3A_RAT / Q99NA5 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha; EC 1.1.1.41 from Rattus norvegicus (Rat) (see paper)
Q99NA5 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rattus norvegicus (see paper)
29% identity, 95% coverage

LOC107804365 isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial-like from Nicotiana tabacum
32% identity, 89% coverage

Q6CA33 isocitrate dehydrogenase (NAD(+)) from Yarrowia lipolytica (strain CLIB 122 / E 150)
32% identity, 95% coverage

IDH1_ARATH / Q8LFC0 Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial; IDH-I; Isocitric dehydrogenase 1; NAD(+)-specific ICDH 1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q8LFC0 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
AT4G35260, NP_195252 isocitrate dehydrogenase 1 from Arabidopsis thaliana
NP_195252 IDH1 (ISOCITRATE DEHYDROGENASE 1); isocitrate dehydrogenase (NAD+)/ oxidoreductase, acting on the CH-OH group of donors, NAD or NADP as acceptor from Arabidopsis thaliana
32% identity, 89% coverage

MMP0880 2-oxosuberate synthase, last step from Methanococcus maripaludis S2
29% identity, 90% coverage

Pyrde_1536 isocitrate/isopropylmalate dehydrogenase family protein from Pyrodictium delaneyi
33% identity, 92% coverage

M1BEG6 NAD-dependent isocitrate dehydrogenase from Solanum tuberosum
31% identity, 95% coverage

PF0940 3-isopropylmalate dehydrogenase 2 from Pyrococcus furiosus DSM 3638
34% identity, 95% coverage

LOC112172665 isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial from Rosa chinensis
31% identity, 88% coverage

3blwF / P28241 Yeast isocitrate dehydrogenase with citrate and amp bound in the regulatory subunits (see paper)
30% identity, 95% coverage

NP_001234366 isocitrate dehydrogenase [NAD] regulatory subunit 1 from Solanum lycopersicum
30% identity, 95% coverage

LOC18035427 isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial from Citrus x clementina
30% identity, 95% coverage

AM1131 isocitrate dehydrogenase from Anaplasma marginale str. St. Maries
31% identity, 81% coverage

RHTO_01289 isocitrate dehydrogenase (NAD+) from Rhodotorula toruloides NP11
31% identity, 95% coverage

Marky_1533 isocitrate/isopropylmalate dehydrogenase family protein from Marinithermus hydrothermalis DSM 14884
32% identity, 89% coverage

Q6ZI55 NAD-dependent isocitrate dehydrogenase c2 from Oryza sativa subsp. japonica
31% identity, 87% coverage

IDH-II / P93032 NAD+-dependent isocitrate dehydrogenase regulatory subunit (EC 1.1.1.286) from Arabidopsis thaliana (see paper)
IDH2_ARATH / P93032 Isocitrate dehydrogenase [NAD] regulatory subunit 2, mitochondrial; IDH-II; Isocitric dehydrogenase 2; NAD(+)-specific ICDH 2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
P93032 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see 2 papers)
AT2G17130 IDH2 (ISOCITRATE DEHYDROGENASE SUBUNIT 2); isocitrate dehydrogenase (NAD+)/ oxidoreductase, acting on the CH-OH group of donors, NAD or NADP as acceptor from Arabidopsis thaliana
32% identity, 87% coverage

CNAG_07363 isocitrate dehydrogenase, NAD-dependent from Cryptococcus neoformans var. grubii H99
32% identity, 90% coverage

EHS24_002540 NAD-dependent isocitrate dehydrogenase from Apiotrichum porosum
32% identity, 90% coverage

Sb04g024840 No description from Sorghum bicolor
31% identity, 87% coverage

EHS24_002733 isocitrate dehydrogenase (NAD(+)) idh1 from Apiotrichum porosum
30% identity, 87% coverage

Mrub_2738 3-isopropylmalate dehydrogenase from Meiothermus ruber DSM 1279
31% identity, 89% coverage

G1APK2 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rhodotorula toruloides (see paper)
31% identity, 95% coverage

NP_849963 isocitrate dehydrogenase subunit 2 from Arabidopsis thaliana
32% identity, 87% coverage

CNA04610 isocitrate dehydrogenase from Cryptococcus neoformans var. neoformans JEC21
31% identity, 90% coverage

MCP_0437 isocitrate/isopropylmalate dehydrogenase family protein from Methanocella paludicola SANAE
31% identity, 95% coverage

PAAG_00856 isocitrate dehydrogenase subunit 1 from Paracoccidioides lutzii Pb01
29% identity, 95% coverage

aksF / Q58991 NAD-dependent threo-isocitrate dehydrogenase (EC 1.1.1.87) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
AKSF_METJA / Q58991 Homoisocitrate dehydrogenase; HICDH; Homo(2)-isocitrate/homo(3)-isocitrate dehydrogenase; Isohomocitrate dehydrogenase; IHDH; NAD-dependent threo-isohomocitrate dehydrogenase; EC 1.1.1.87; EC 1.1.1.- from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
Q58991 methanogen homoaconitase (EC 4.2.1.114) from Methanocaldococcus jannaschii (see paper)
28% identity, 94% coverage

MJ1596 3-isopropylmalate dehydrogenase 2 (leuB2) from Methanocaldococcus jannaschii DSM 2661
28% identity, 94% coverage

G1APK3 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rhodotorula toruloides (see paper)
30% identity, 95% coverage

I1IYV8 Isopropylmalate dehydrogenase-like domain-containing protein from Brachypodium distachyon
29% identity, 95% coverage

I1IB67 Isopropylmalate dehydrogenase-like domain-containing protein from Brachypodium distachyon
30% identity, 87% coverage

RHTO_01290 isocitrate dehydrogenase (NAD+) from Rhodotorula toruloides NP11
30% identity, 95% coverage

AO090003000008 No description from Aspergillus oryzae RIB40
29% identity, 90% coverage

LOC18037111 isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial from Citrus x clementina
30% identity, 89% coverage

IDH3_ARATH / O81796 Isocitrate dehydrogenase [NAD] regulatory subunit 3, mitochondrial; IDH-III; Isocitric dehydrogenase 3; NAD(+)-specific ICDH 3 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
O81796 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Arabidopsis thaliana (see paper)
NP_195290 isocitrate dehydrogenase III from Arabidopsis thaliana
AT4G35650 isocitrate dehydrogenase, putative / NAD+ isocitrate dehydrogenase, putative from Arabidopsis thaliana
30% identity, 87% coverage

Q4WNH3 isocitrate dehydrogenase (NAD(+)) from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)
28% identity, 85% coverage

An18g06760 uncharacterized protein from Aspergillus niger
28% identity, 90% coverage

LYS12_YEAST / P40495 Homoisocitrate dehydrogenase, mitochondrial; HIcDH; EC 1.1.1.87 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P40495 homoisocitrate dehydrogenase (EC 1.1.1.87) from Saccharomyces cerevisiae (see 2 papers)
YIL094C Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate from Saccharomyces cerevisiae
NP_012172 homoisocitrate dehydrogenase from Saccharomyces cerevisiae S288C
31% identity, 87% coverage

MA4265 isocitrate/isopropylmalate dehydrogenase family protein from Methanosarcina acetivorans C2A
30% identity, 94% coverage

IDH1_SCHPO / O13696 Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
idh1 / RF|NP_594397.1 isocitrate dehydrogenase (NAD+) subunit 1 Idh1; EC 1.1.1.41 from Schizosaccharomyces pombe (see 3 papers)
SPAC11G7.03 isocitrate dehydrogenase (NAD+) subunit 1 Idh1 (PMID 10975257) from Schizosaccharomyces pombe
30% identity, 90% coverage

Ocepr_1387 No description from Oceanithermus profundus 506, DSM 14977
30% identity, 89% coverage

3asjA / Q5SIJ1 Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor (see paper)
31% identity, 89% coverage

hicdh / Q5SIJ1 homoisocitrate dehydrogenase subunit (EC 1.1.1.87) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET8 / Q5SIJ1 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET2 / Q72IW9 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 4 papers)
Q5SIJ1 homoisocitrate dehydrogenase (EC 1.1.1.87) from Thermus thermophilus (see paper)
TTC1012 No description from Thermus thermophilus HB27
TTHA1378 homoisocitrate dehydrogenase from Thermus thermophilus HB8
31% identity, 89% coverage

BBA_01606 isocitrate/isopropylmalate dehydrogenase from Beauveria bassiana ARSEF 2860
31% identity, 85% coverage

Q5A9D9 Homoisocitrate dehydrogenase from Candida albicans (strain SC5314 / ATCC MYA-2876)
31% identity, 89% coverage

MMP0539 3-isopropylmalate dehydrogenase from Methanococcus maripaludis S2
29% identity, 95% coverage

NCU00775 isocitrate dehydrogenase subunit 1 from Neurospora crassa OR74A
27% identity, 95% coverage

ecm3 / Q0X0C1 (2S,3R)-2-[(2-aminophenyl)amino]-3-carboxy-3-hydroxypropanoate dehydrogenase from Streptomyces lasalocidi (see 2 papers)
33% identity, 84% coverage

PAS_chr4_0580 Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase from Komagataella phaffii GS115
30% identity, 95% coverage

3blvC / P28834 Yeast isocitrate dehydrogenase with citrate bound in the regulatory subunits (see paper)
29% identity, 95% coverage

EHI_143560 tartrate dehydrogenase, putative from Entamoeba histolytica HM-1:IMSS
29% identity, 94% coverage

TSC_c20650 homoisocitrate dehydrogenase from Thermus scotoductus SA-01
31% identity, 87% coverage

HCAG_04093 isocitrate dehydrogenase subunit 1, mitochondrial precursor from Histoplasma mississippiense (nom. inval.)
30% identity, 83% coverage

CNAG_07851 isocitrate dehydrogenase, NAD-dependent from Cryptococcus neoformans var. grubii H99
29% identity, 85% coverage

cg1453 3-isopropylmalate dehydrogenase from Corynebacterium glutamicum ATCC 13032
30% identity, 95% coverage

IHV18_09900 3-isopropylmalate dehydrogenase from Bifidobacterium breve
31% identity, 87% coverage

Mmah_0582 isocitrate dehydrogenase (NADP) from Methanohalophilus mahii DSM 5219
30% identity, 89% coverage

IDH1 / P28834 isocitrate dehydrogenase [NAD] α subunit (EC 1.1.1.286) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
IDH1_YEAST / P28834 Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P28834 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Saccharomyces cerevisiae (see paper)
YNL037C Idh1p from Saccharomyces cerevisiae
NP_014361 isocitrate dehydrogenase (NAD(+)) IDH1 from Saccharomyces cerevisiae S288C
29% identity, 95% coverage

BBMN68_984 3-isopropylmalate dehydrogenase from Bifidobacterium longum subsp. longum BBMN68
31% identity, 87% coverage

MSMEG_2379 3-isopropylmalate dehydrogenase from Mycobacterium smegmatis str. MC2 155
32% identity, 89% coverage

B7Z9J8 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial from Homo sapiens
30% identity, 75% coverage

VDAG_01116 homoisocitrate dehydrogenase from Verticillium dahliae VdLs.17
30% identity, 83% coverage

New Search

For advice on how to use these tools together, see Interactive tools for functional annotation of bacterial genomes.

Statistics

The PaperBLAST database links 789,361 different protein sequences to 1,256,019 scientific articles. Searches against EuropePMC were last performed on January 10 2025.

How It Works

PaperBLAST builds a database of protein sequences that are linked to scientific articles. These links come from automated text searches against the articles in EuropePMC and from manually-curated information from GeneRIF, UniProtKB/Swiss-Prot, BRENDA, CAZy (as made available by dbCAN), BioLiP, CharProtDB, MetaCyc, EcoCyc, TCDB, REBASE, the Fitness Browser, and a subset of the European Nucleotide Archive with the /experiment tag. Given this database and a protein sequence query, PaperBLAST uses protein-protein BLAST to find similar sequences with E < 0.001.

To build the database, we query EuropePMC with locus tags, with RefSeq protein identifiers, and with UniProt accessions. We obtain the locus tags from RefSeq or from MicrobesOnline. We use queries of the form "locus_tag AND genus_name" to try to ensure that the paper is actually discussing that gene. Because EuropePMC indexes most recent biomedical papers, even if they are not open access, some of the links may be to papers that you cannot read or that our computers cannot read. We query each of these identifiers that appears in the open access part of EuropePMC, as well as every locus tag that appears in the 500 most-referenced genomes, so that a gene may appear in the PaperBLAST results even though none of the papers that mention it are open access. We also incorporate text-mined links from EuropePMC that link open access articles to UniProt or RefSeq identifiers. (This yields some additional links because EuropePMC uses different heuristics for their text mining than we do.)

For every article that mentions a locus tag, a RefSeq protein identifier, or a UniProt accession, we try to select one or two snippets of text that refer to the protein. If we cannot get access to the full text, we try to select a snippet from the abstract, but unfortunately, unique identifiers such as locus tags are rarely provided in abstracts.

PaperBLAST also incorporates manually-curated protein functions:

Except for GeneRIF and ENA, the curated entries include a short curated description of the protein's function. For entries from BioLiP, the protein's function may not be known beyond binding to the ligand. Many of these entries also link to articles in PubMed.

For more information see the PaperBLAST paper (mSystems 2017) or the code. You can download PaperBLAST's database here.

Changes to PaperBLAST since the paper was written:

Many of these changes are described in Interactive tools for functional annotation of bacterial genomes.

Secrets

PaperBLAST cannot provide snippets for many of the papers that are published in non-open-access journals. This limitation applies even if the paper is marked as "free" on the publisher's web site and is available in PubmedCentral or EuropePMC. If a journal that you publish in is marked as "secret," please consider publishing elsewhere.

Omissions from the PaperBLAST Database

Many important articles are missing from PaperBLAST, either because the article's full text is not in EuropePMC (as for many older articles), or because the paper does not mention a protein identifier such as a locus tag, or because of PaperBLAST's heuristics. If you notice an article that characterizes a protein's function but is missing from PaperBLAST, please notify the curators at UniProt or add an entry to GeneRIF. Entries in either of these databases will eventually be incorporated into PaperBLAST. Note that to add an entry to UniProt, you will need to find the UniProt identifier for the protein. If the protein is not already in UniProt, you can ask them to create an entry. To add an entry to GeneRIF, you will need an NCBI Gene identifier, but unfortunately many prokaryotic proteins in RefSeq do not have corresponding Gene identifers.

References

PaperBLAST: Text-mining papers for information about homologs.
M. N. Price and A. P. Arkin (2017). mSystems, 10.1128/mSystems.00039-17.

Europe PMC in 2017.
M. Levchenko et al (2017). Nucleic Acids Research, 10.1093/nar/gkx1005.

Gene indexing: characterization and analysis of NLM's GeneRIFs.
J. A. Mitchell et al (2003). AMIA Annu Symp Proc 2003:460-464.

UniProt: the universal protein knowledgebase.
The UniProt Consortium (2016). Nucleic Acids Research, 10.1093/nar/gkw1099.

BRENDA in 2017: new perspectives and new tools in BRENDA.
S. Placzek et al (2017). Nucleic Acids Research, 10.1093/nar/gkw952.

The EcoCyc database: reflecting new knowledge about Escherichia coli K-12.
I. M. Keeseler et al (2016). Nucleic Acids Research, 10.1093/nar/gkw1003.

The MetaCyc database of metabolic pathways and enzymes.
R. Caspi et al (2018). Nucleic Acids Research, 10.1093/nar/gkx935.

CharProtDB: a database of experimentally characterized protein annotations.
R. Madupu et al (2012). Nucleic Acids Research, 10.1093/nar/gkr1133.

The carbohydrate-active enzymes database (CAZy) in 2013.
V. Lombard et al (2014). Nucleic Acids Research, 10.1093/nar/gkt1178.

The Transporter Classification Database (TCDB): recent advances
M. H. Saier, Jr. et al (2016). Nucleic Acids Research, 10.1093/nar/gkv1103.

REBASE - a database for DNA restriction and modification: enzymes, genes and genomes.
R. J. Roberts et al (2015). Nucleic Acids Research, 10.1093/nar/gku1046.

Deep annotation of protein function across diverse bacteria from mutant phenotypes.
M. N. Price et al (2016). bioRxiv, 10.1101/072470.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory