PaperBLAST – Find papers about a protein or its homologs

 

PaperBLAST

PaperBLAST Hits for sp|Q5UZ46|ASSY_HALMA Argininosuccinate synthase OS=Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) OX=272569 GN=argG PE=3 SV=1 (420 a.a., MPEGNGTVAL...)

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Find functional residues: SitesBLAST

Search for conserved domains

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Compare to protein structures

Predict transmenbrane helices: Phobius

Predict protein localization: PSORTb

Find homologs in fast.genomics

Fitness BLAST: loading...

Found 180 similar proteins in the literature:

HVO_0049 argininosuccinate synthase from Haloferax volcanii DS2
74% identity, 96% coverage

PF0207 argininosuccinate synthase from Pyrococcus furiosus DSM 3638
47% identity, 93% coverage

BLJ_0642 argininosuccinate synthase from Bifidobacterium longum subsp. longum JDM301
43% identity, 92% coverage

Igni_0635 argininosuccinate synthase from Ignicoccus hospitalis KIN4/I
46% identity, 86% coverage

alr4798 argininosuccinate synthase from Nostoc sp. PCC 7120
43% identity, 91% coverage

B1W3B3 Argininosuccinate synthase from Streptomyces griseus subsp. griseus (strain JCM 4626 / CBS 651.72 / NBRC 13350 / KCC S-0626 / ISP 5235)
42% identity, 92% coverage

BSU29450 argininosuccinate synthase from Bacillus subtilis subsp. subtilis str. 168
44% identity, 91% coverage

GL331_18120 argininosuccinate synthase from Bacillus velezensis
44% identity, 91% coverage

argG / CAA88926.1 argininosuccinate synthetase from Streptomyces clavuligerus (see 3 papers)
BB341_RS23970, SCLAV_0796 argininosuccinate synthase from Streptomyces clavuligerus
42% identity, 92% coverage

ATE50_RS06345 argininosuccinate synthase from Bacillus velezensis
44% identity, 91% coverage

MAP_RS06945 argininosuccinate synthase from Mycobacterium avium subsp. paratuberculosis K-10
MAP1367 ArgG from Mycobacterium avium subsp. paratuberculosis str. k10
42% identity, 92% coverage

NCgl1346 argininosuccinate synthase from Corynebacterium glutamicum ATCC 13032
cg1586 argininosuccinate synthase from Corynebacterium glutamicum ATCC 13032
41% identity, 92% coverage

ASSY_SYNY3 / P77973 Argininosuccinate synthase; Argininosuccinate synthetase; Citrulline--aspartate ligase; SyArgG; EC 6.3.4.5 from Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa) (see paper)
slr0585 argininosuccinate synthetase from Synechocystis sp. PCC 6803
45% identity, 86% coverage

FRAAL5202 Argininosuccinate synthase (Citrulline--aspartate ligase) from Frankia alni ACN14a
43% identity, 91% coverage

GBAA4880 argininosuccinate synthase from Bacillus anthracis str. 'Ames Ancestor'
42% identity, 92% coverage

Rv1658 argininosuccinate synthase from Mycobacterium tuberculosis H37Rv
43% identity, 92% coverage

SXYL_01961 argininosuccinate synthase from Staphylococcus xylosus
42% identity, 91% coverage

MAB_2342 Argininosuccinate synthase ArgG from Mycobacterium abscessus ATCC 19977
41% identity, 93% coverage

B1YJ35 Argininosuccinate synthase from Exiguobacterium sibiricum (strain DSM 17290 / CCUG 55495 / CIP 109462 / JCM 13490 / 255-15)
44% identity, 90% coverage

4xfjB / G7CBN9 Crystal structure of argininosuccinate synthase from mycobacterium thermoresistibile in complex with amppnp and arginine
41% identity, 92% coverage

MSMEG_3770 argininosuccinate synthase from Mycobacterium smegmatis str. MC2 155
41% identity, 92% coverage

lmo2090 similar to argininosuccinate synthase from Listeria monocytogenes EGD-e
43% identity, 91% coverage

T303_00025 argininosuccinate synthase from Streptococcus thermophilus ASCC 1275
41% identity, 92% coverage

LLNZ_00730 argininosuccinate synthase from Lactococcus cremoris subsp. cremoris NZ9000
41% identity, 92% coverage

llmg_0138 ArgG protein from Lactococcus lactis subsp. cremoris MG1363
41% identity, 92% coverage

Vpar_1568 argininosuccinate synthase from Veillonella parvula DSM 2008
41% identity, 91% coverage

TTX_0123 argininosuccinate synthase from Thermoproteus tenax Kra 1
44% identity, 92% coverage

LOC108992980 argininosuccinate synthase, chloroplastic from Juglans regia
42% identity, 78% coverage

SE0657 argininosuccinate synthase from Staphylococcus epidermidis ATCC 12228
SERP_RS02815 argininosuccinate synthase from Staphylococcus epidermidis RP62A
41% identity, 91% coverage

Teth39_0229 argininosuccinate synthase from Thermoanaerobacter ethanolicus ATCC 33223
42% identity, 91% coverage

ILP78_10355 argininosuccinate synthase from Staphylococcus aureus
40% identity, 91% coverage

XP_002521168 argininosuccinate synthase, chloroplastic from Ricinus communis
43% identity, 78% coverage

spr0102 Argininosuccinate synthase from Streptococcus pneumoniae R6
41% identity, 94% coverage

SPD_0110 argininosuccinate synthase from Streptococcus pneumoniae D39
41% identity, 94% coverage

Q2QVC1 argininosuccinate synthase from Oryza sativa subsp. japonica
42% identity, 80% coverage

Q6GIC7 Argininosuccinate synthase from Staphylococcus aureus (strain MRSA252)
SAR0923 putative argininosuccinate synthase from Staphylococcus aureus subsp. aureus MRSA252
DA471_RS02560 argininosuccinate synthase from Staphylococcus aureus
40% identity, 91% coverage

NWMN_0832 argininosuccinate synthase from Staphylococcus aureus subsp. aureus str. Newman
SA0822 argininosuccinate synthase from Staphylococcus aureus subsp. aureus N315
SAOUHSC_00899 argininosuccinate synthase from Staphylococcus aureus subsp. aureus NCTC 8325
SAUSA300_0864 argininosuccinate synthase from Staphylococcus aureus subsp. aureus USA300_FPR3757
SACOL0964 argininosuccinate synthase from Staphylococcus aureus subsp. aureus COL
BTN44_08010, NWMN_RS04695 argininosuccinate synthase from Staphylococcus aureus subsp. aureus str. Newman
40% identity, 91% coverage

SGO_0175 argininosuccinate synthase from Streptococcus gordonii str. Challis substr. CH1
41% identity, 91% coverage

Q9SZX3 Argininosuccinate synthase, chloroplastic from Arabidopsis thaliana
42% identity, 78% coverage

SSA_2142 Argininosuccinate synthase, putative from Streptococcus sanguinis SK36
41% identity, 91% coverage

SAN_0156 argininosuccinate synthase from Streptococcus agalactiae COH1
39% identity, 92% coverage

XP_002311011 argininosuccinate synthase, chloroplastic from Populus trichocarpa
43% identity, 78% coverage

B4FZ29 argininosuccinate synthase from Zea mays
42% identity, 86% coverage

LOC110703812 argininosuccinate synthase, chloroplastic-like from Chenopodium quinoa
42% identity, 77% coverage

lp_0775 argininosuccinate synthase from Lactiplantibacillus plantarum WCFS1
lp_0775 argininosuccinate synthase from Lactobacillus plantarum WCFS1
41% identity, 94% coverage

Saci_1617 arginosuccinate synthase from Sulfolobus acidocaldarius DSM 639
39% identity, 92% coverage

A0A438K994 argininosuccinate synthase from Vitis vinifera
42% identity, 29% coverage

LMB90_RS03525 argininosuccinate synthase from Limosilactobacillus reuteri
41% identity, 90% coverage

H9BG20 argininosuccinate synthase (EC 6.3.4.5) from Leishmania donovani (see 2 papers)
41% identity, 92% coverage

A4I066 argininosuccinate synthase (EC 6.3.4.5) from Leishmania infantum (see paper)
XP_003860931 argininosuccinate synthase, putative from Leishmania donovani
41% identity, 92% coverage

A8J506 argininosuccinate synthase from Chlamydomonas reinhardtii
40% identity, 87% coverage

CAC0973 Argininosuccinate synthase from Clostridium acetobutylicum ATCC 824
CA_C0973, CEA_G0984 argininosuccinate synthase from Clostridium acetobutylicum EA 2018
41% identity, 91% coverage

FQP81_07870 argininosuccinate synthase from Pseudoalteromonas distincta
41% identity, 92% coverage

CD1785 argininosuccinate synthase from Clostridium difficile 630
42% identity, 85% coverage

CPE0691 argininosuccinate synthase from Clostridium perfringens str. 13
40% identity, 92% coverage

ZMO1036 argininosuccinate synthase from Zymomonas mobilis subsp. mobilis ZM4
40% identity, 93% coverage

RSP_1212 ArgG, Argininosuccinate synthase from Rhodobacter sphaeroides 2.4.1
40% identity, 91% coverage

GSU0153 argininosuccinate synthase from Geobacter sulfurreducens PCA
39% identity, 91% coverage

Cbei_4515 argininosuccinate synthase from Clostridium beijerincki NCIMB 8052
39% identity, 94% coverage

RL2987 putative argininosuccinate synthase from Rhizobium leguminosarum bv. viciae 3841
38% identity, 91% coverage

AL01_09265 argininosuccinate synthase from Bombella intestini
40% identity, 93% coverage

DR0674 arginosuccinate synthase from Deinococcus radiodurans R1
38% identity, 94% coverage

ASSY_THEMA / Q9X2A1 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
TM1780 argininosuccinate synthase from Thermotoga maritima MSB8
39% identity, 91% coverage

SPO0018 argininosuccinate synthase from Ruegeria pomeroyi DSS-3
39% identity, 91% coverage

CJE0767 argininosuccinate synthase from Campylobacter jejuni RM1221
38% identity, 92% coverage

Cj0665c argininosuccinate synthase from Campylobacter jejuni subsp. jejuni NCTC 11168
38% identity, 92% coverage

lpg0494 argininosuccinate synthase from Legionella pneumophila subsp. pneumophila str. Philadelphia 1
39% identity, 92% coverage

PAE2884 argininosuccinate synthase (argG) from Pyrobaculum aerophilum str. IM2
48% identity, 67% coverage

SO_0278 argininosuccinate synthase from Shewanella oneidensis MR-1
40% identity, 92% coverage

K3G22_18080 argininosuccinate synthase from Shewanella putrefaciens
40% identity, 92% coverage

A7ML85 Argininosuccinate synthase from Cronobacter sakazakii (strain ATCC BAA-894)
39% identity, 95% coverage

TTC1701 No description from Thermus thermophilus HB27
41% identity, 91% coverage

VV1_1373 argininosuccinate synthase from Vibrio vulnificus CMCP6
40% identity, 91% coverage

NSCAC_0583 argininosuccinate synthase from Candidatus Nitrosacidococcus tergens
38% identity, 91% coverage

PflSS101_1161 argininosuccinate synthase from Pseudomonas lactis
38% identity, 92% coverage

PA3525 argininosuccinate synthase from Pseudomonas aeruginosa PAO1
PA14_18740 argininosuccinate synthase from Pseudomonas aeruginosa UCBPP-PA14
38% identity, 92% coverage

CHLNCDRAFT_52216 hypothetical protein from Chlorella variabilis
E1ZF33 argininosuccinate synthase from Chlorella variabilis
39% identity, 86% coverage

PITG_05374 argininosuccinate synthase from Phytophthora infestans T30-4
39% identity, 78% coverage

PP1088, PP_1088 argininosuccinate synthase from Pseudomonas putida KT2440
38% identity, 92% coverage

CPH89_RS16850 argininosuccinate synthase from Pseudomonas fluorescens
38% identity, 92% coverage

VZ55_RS10120 argininosuccinate synthase from Gluconobacter oxydans
39% identity, 95% coverage

ASSY_THET8 / P59846 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 2 papers)
TTHA0284 argininosuccinate synthetase from Thermus thermophilus HB8
41% identity, 91% coverage

VFMJ11_2416 argininosuccinate synthase from Vibrio fischeri MJ11
VFMJ11_2416 argininosuccinate synthase from Aliivibrio fischeri MJ11
39% identity, 91% coverage

PHYSODRAFT_485399 hypothetical protein from Phytophthora sojae
39% identity, 86% coverage

VP2757 argininosuccinate synthase from Vibrio parahaemolyticus RIMD 2210633
39% identity, 93% coverage

RL4515 putative argininosuccinate synthase from Rhizobium leguminosarum bv. viciae 3841
38% identity, 92% coverage

BAU10_13660 argininosuccinate synthase from Vibrio alginolyticus
39% identity, 93% coverage

BAB1_0071 Argininosuccinate synthase from Brucella melitensis biovar Abortus 2308
37% identity, 91% coverage

LHK_02172 AssY from Laribacter hongkongensis HLHK9
38% identity, 92% coverage

7k5zA / Q5ZY78 Crystal structure of argininosuccinate synthase from legionella pneumophila philadelphia 1 in complex with anppnp and a substrate analogue arginine
39% identity, 89% coverage

Q92L73 Argininosuccinate synthase from Rhizobium meliloti (strain 1021)
SMc03826 argininosuccinate synthase from Sinorhizobium meliloti 1021
37% identity, 91% coverage

Gasu_30780 argininosuccinate synthase from Galdieria sulphuraria
38% identity, 93% coverage

ARG1 argininosuccinate synthase; EC 6.3.4.5 from Candida albicans (see paper)
40% identity, 80% coverage

1j1zA / P59846 Crystal structure of thermus thermophilus hb8 argininosuccinate synthetase in complex with substrate (see paper)
40% identity, 91% coverage

VC2642 argininosuccinate synthase from Vibrio cholerae O1 biovar eltor str. N16961
39% identity, 91% coverage

PMI3239 argininosuccinate synthase from Proteus mirabilis HI4320
38% identity, 93% coverage

Q2Z0F6 argininosuccinate synthase (EC 6.3.4.5) from Agaricus bisporus (see paper)
39% identity, 89% coverage

plu4742 argininosuccinate synthase (citrulline-aspartate ligase) from Photorhabdus luminescens subsp. laumondii TTO1
38% identity, 91% coverage

A4X2R7 Argininosuccinate synthase from Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / JCM 13857 / NBRC 105044 / CNB-440)
39% identity, 91% coverage

EAMY_0145 Argininosuccinate synthase from Erwinia amylovora CFBP1430
38% identity, 91% coverage

argG / CAB95023.1 argininosuccinate synthetase from Moritella abyssi (see paper)
38% identity, 93% coverage

AT4G24830 arginosuccinate synthase family from Arabidopsis thaliana
B3H778 argininosuccinate synthase from Arabidopsis thaliana
39% identity, 85% coverage

Q4WHT0 argininosuccinate synthase from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)
AFUA_2G04310 argininosuccinate synthase from Aspergillus fumigatus Af293
41% identity, 86% coverage

G4MTK2 argininosuccinate synthase from Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)
38% identity, 96% coverage

CNAG_00930 argininosuccinate synthase from Cryptococcus neoformans var. grubii H99
40% identity, 88% coverage

CC0129 argininosuccinate synthase from Caulobacter crescentus CB15
37% identity, 92% coverage

S4V5K7 argininosuccinate synthase (EC 6.3.4.5) from Protopterus annectens (see paper)
36% identity, 90% coverage

TEL01S_RS01770 argininosuccinate synthase from Pseudothermotoga elfii DSM 9442 = NBRC 107921
35% identity, 92% coverage

MUW98_RS20405 argininosuccinate synthase from Aeromonas hydrophila
37% identity, 92% coverage

Q6FWJ8 argininosuccinate synthase from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138)
38% identity, 92% coverage

ASSY_SCHPO / O94354 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
arg12 / RF|NP_595183.1 argininosuccinate synthase (predicted); EC 6.3.4.5 from Schizosaccharomyces pombe (see 2 papers)
SPBC428.05c argininosuccinate synthase (predicted) from Schizosaccharomyces pombe
40% identity, 87% coverage

An15g02340 uncharacterized protein from Aspergillus niger
38% identity, 91% coverage

B5Y3V3 argininosuccinate synthase from Phaeodactylum tricornutum (strain CCAP 1055/1)
36% identity, 89% coverage

AO090023000395 No description from Aspergillus oryzae RIB40
39% identity, 82% coverage

M7WMY0 argininosuccinate synthase from Rhodotorula toruloides (strain NP11)
37% identity, 91% coverage

NP_001004603 argininosuccinate synthase from Danio rerio
Q66I24 Argininosuccinate synthase from Danio rerio
35% identity, 96% coverage

ASSY_RAT / P09034 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Rattus norvegicus (Rat) (see paper)
XP_006233973 argininosuccinate synthase isoform X1 from Rattus norvegicus
36% identity, 93% coverage

ASSY_BOVIN / P14568 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Bos taurus (Bovine) (see paper)
NP_776317 argininosuccinate synthase from Bos taurus
36% identity, 93% coverage

ASSY_MOUSE / P16460 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Mus musculus (Mouse) (see 3 papers)
P16460 argininosuccinate synthase (EC 6.3.4.5) from Mus musculus (see 4 papers)
Q3UJ34 Argininosuccinate synthase from Mus musculus
NP_031520 argininosuccinate synthase from Mus musculus
36% identity, 93% coverage

XP_003353734 argininosuccinate synthase from Sus scrofa
36% identity, 93% coverage

ASS1 / P00966 Argininosuccinate synthase (EC 6.3.4.5) from Homo sapiens (see 7 papers)
ASSY_HUMAN / P00966 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Homo sapiens (Human) (see 21 papers)
P00966 argininosuccinate synthase (EC 6.3.4.5) from Homo sapiens (see 9 papers)
NP_000041 argininosuccinate synthase from Homo sapiens
36% identity, 93% coverage

YOL058W Arg1p from Saccharomyces cerevisiae
38% identity, 91% coverage

FOXG_13797 argininosuccinate synthase from Fusarium oxysporum f. sp. lycopersici 4287
35% identity, 85% coverage

ASSY_YEAST / P22768 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
NP_014583 argininosuccinate synthase from Saccharomyces cerevisiae S288C
38% identity, 91% coverage

2nz2A / P00966 Crystal structure of human argininosuccinate synthase in complex with aspartate and citrulline (see paper)
36% identity, 92% coverage

PADG_00888 argininosuccinate synthase from Paracoccidioides brasiliensis Pb18
39% identity, 88% coverage

LOC107453461 argininosuccinate synthase from Parasteatoda tepidariorum
37% identity, 91% coverage

FGSG_06098 argininosuccinate synthase from Fusarium graminearum PH-1
36% identity, 96% coverage

BPSL1721 putative argininosuccinate synthase from Burkholderia pseudomallei K96243
35% identity, 91% coverage

PAAG_07114 argininosuccinate synthase from Paracoccidioides lutzii Pb01
38% identity, 88% coverage

E3JT53 argininosuccinate synthase from Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL)
36% identity, 90% coverage

HL033_04485 argininosuccinate synthase from Neoehrlichia mikurensis
37% identity, 86% coverage

PD0291 argininosuccinate synthase from Xylella fastidiosa Temecula1
36% identity, 92% coverage

ING2E5A_0737 argininosuccinate synthase from Petrimonas mucosa
35% identity, 90% coverage

XF0999 argininosuccinate synthase from Xylella fastidiosa 9a5c
35% identity, 92% coverage

Q0IFL5 Argininosuccinate synthase from Aedes aegypti
32% identity, 94% coverage

A0A401P304 Argininosuccinate synthase from Scyliorhinus torazame
33% identity, 94% coverage

PXO_00352 argininosuccinate synthase from Xanthomonas oryzae pv. oryzae PXO99A
35% identity, 93% coverage

ABZR86_RS08715 arginosuccinate synthetase (EC 6.3.4.5) from Dyella japonica UNC79MFTsu3.2
35% identity, 91% coverage

Smlt3301 putative argininosuccinate synthase from Stenotrophomonas maltophilia K279a
34% identity, 93% coverage

SPRG_19437 argininosuccinate synthase from Saprolegnia parasitica CBS 223.65
32% identity, 92% coverage

A0A0B4F537 argininosuccinate synthase (Fragment) from Metarhizium anisopliae (strain ARSEF 549)
32% identity, 90% coverage

BF9343_0461 argininosuccinate synthase from Bacteroides fragilis NCTC 9343
29% identity, 90% coverage

BT3760 arginosuccinate synthetase (EC 6.3.4.5) from Bacteroides thetaiotaomicron VPI-5482
BT3760 argininosuccinate synthase from Bacteroides thetaiotaomicron VPI-5482
28% identity, 91% coverage

An12g01280 uncharacterized protein from Aspergillus niger
30% identity, 81% coverage

HI1727 argininosuccinate synthetase (argG) from Haemophilus influenzae Rd KW20
28% identity, 77% coverage

5us8A / Q7VTJ9 2.15 angstrom resolution crystal structure of argininosuccinate synthase from bordetella pertussis
28% identity, 82% coverage

BB1986 argininosuccinate synthase from Bordetella bronchiseptica RB50
27% identity, 82% coverage

LV28_16050 argininosuccinate synthase from Pandoraea pnomenusa
28% identity, 77% coverage

PPA2201 argininosuccinate synthase from Propionibacterium acnes KPA171202
28% identity, 76% coverage

Sant_2433 argininosuccinate synthase from Sodalis praecaptivus
27% identity, 84% coverage

PFREUD_01460 argininosuccinate synthase from Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1
27% identity, 77% coverage

1kp3A / P0A6E4 Crystal structure of e. Coli argininosuccinate synthetase in complex with atp and citrulline (see paper)
26% identity, 86% coverage

SLIV_04065 argininosuccinate synthase from Streptomyces lividans TK24
SCO7036 argininosuccinate synthase from Streptomyces coelicolor A3(2)
27% identity, 76% coverage

YPO1570 argininosuccinate synthase from Yersinia pestis CO92
Q8ZFV7 Argininosuccinate synthase from Yersinia pestis
YPTB1579 argininosuccinate synthase from Yersinia pseudotuberculosis IP 32953
29% identity, 62% coverage

FQU82_01177, HMPREF0010_02972 argininosuccinate synthase from Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841
29% identity, 61% coverage

AB57_1152 argininosuccinate synthase from Acinetobacter baumannii AB0057
29% identity, 62% coverage

STM3290 argininosuccinate synthetase from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
26% identity, 73% coverage

STM3290.S argininosuccinate synthase from Salmonella typhimurium LT2
STM14_3973 argininosuccinate synthase from Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S
26% identity, 77% coverage

ArgG / b3172 argininosuccinate synthetase (EC 6.3.4.5) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ASSY_ECOLI / P0A6E4 Argininosuccinate synthase; Citrulline--aspartate ligase; EC 6.3.4.5 from Escherichia coli (strain K12) (see 2 papers)
argG / RF|NP_417640 argininosuccinate synthase from Escherichia coli K12 (see paper)
NP_417640 argininosuccinate synthetase from Escherichia coli str. K-12 substr. MG1655
b3172 argininosuccinate synthase from Escherichia coli str. K-12 substr. MG1655
c3929 Argininosuccinate synthase from Escherichia coli CFT073
27% identity, 77% coverage

ECs4052 argininosuccinate synthetase from Escherichia coli O157:H7 str. Sakai
27% identity, 77% coverage

P59609 Argininosuccinate synthase from Shigella flexneri
27% identity, 77% coverage

A6TEJ0 Argininosuccinate synthase from Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
26% identity, 84% coverage

BPSL0298 argininosuccinate synthase from Burkholderia pseudomallei K96243
27% identity, 77% coverage

BCAM0746 argininosuccinate synthase from Burkholderia cenocepacia J2315
26% identity, 85% coverage

argG / BAC65286.1 argininosuccinate synthase from Burkholderia multivorans (see paper)
26% identity, 85% coverage

NGO1961 ArgG from Neisseria gonorrhoeae FA 1090
29% identity, 64% coverage

KPK_0542 argininosuccinate synthase from Klebsiella pneumoniae 342
26% identity, 84% coverage

NMB2129 argininosuccinate synthase from Neisseria meningitidis MC58
29% identity, 64% coverage

B7PA12 argininosuccinate synthase (Fragment) from Ixodes scapularis
35% identity, 29% coverage

HVO_0190 conserved hypothetical protein TIGR00268 from Haloferax volcanii DS2
30% identity, 35% coverage

D9S103 PP-loop domain protein from Thermosediminibacter oceani (strain ATCC BAA-1034 / DSM 16646 / JW/IW-1228P)
29% identity, 38% coverage

V5I554 GMP synthase (glutamine-hydrolyzing) (Fragment) from Ixodes ricinus
37% identity, 10% coverage

GUAA_MOUSE / Q3THK7 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Mus musculus (Mouse) (see paper)
35% identity, 10% coverage

GUAA_RAT / Q4V7C6 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Rattus norvegicus (Rat) (see paper)
35% identity, 10% coverage

2e18A / O57921 Crystal structure of project ph0182 from pyrococcus horikoshii ot3
26% identity, 39% coverage

XP_011511565 GMP synthase [glutamine-hydrolyzing] isoform X1 from Homo sapiens
34% identity, 10% coverage

GUAA_HUMAN / P49915 GMP synthase [glutamine-hydrolyzing]; GMP synthetase; Glutamine amidotransferase; EC 6.3.5.2 from Homo sapiens (Human) (see 2 papers)
P49915 GMP synthase (glutamine-hydrolysing) (EC 6.3.5.2) from Homo sapiens (see paper)
34% identity, 10% coverage

Q53F90 GMP synthase (glutamine-hydrolyzing) (Fragment) from Homo sapiens
34% identity, 10% coverage

2vxoB / P49915 Human gmp synthetase in complex with xmp (see paper)
34% identity, 11% coverage

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Statistics

The PaperBLAST database links 789,361 different protein sequences to 1,256,019 scientific articles. Searches against EuropePMC were last performed on January 10 2025.

How It Works

PaperBLAST builds a database of protein sequences that are linked to scientific articles. These links come from automated text searches against the articles in EuropePMC and from manually-curated information from GeneRIF, UniProtKB/Swiss-Prot, BRENDA, CAZy (as made available by dbCAN), BioLiP, CharProtDB, MetaCyc, EcoCyc, TCDB, REBASE, the Fitness Browser, and a subset of the European Nucleotide Archive with the /experiment tag. Given this database and a protein sequence query, PaperBLAST uses protein-protein BLAST to find similar sequences with E < 0.001.

To build the database, we query EuropePMC with locus tags, with RefSeq protein identifiers, and with UniProt accessions. We obtain the locus tags from RefSeq or from MicrobesOnline. We use queries of the form "locus_tag AND genus_name" to try to ensure that the paper is actually discussing that gene. Because EuropePMC indexes most recent biomedical papers, even if they are not open access, some of the links may be to papers that you cannot read or that our computers cannot read. We query each of these identifiers that appears in the open access part of EuropePMC, as well as every locus tag that appears in the 500 most-referenced genomes, so that a gene may appear in the PaperBLAST results even though none of the papers that mention it are open access. We also incorporate text-mined links from EuropePMC that link open access articles to UniProt or RefSeq identifiers. (This yields some additional links because EuropePMC uses different heuristics for their text mining than we do.)

For every article that mentions a locus tag, a RefSeq protein identifier, or a UniProt accession, we try to select one or two snippets of text that refer to the protein. If we cannot get access to the full text, we try to select a snippet from the abstract, but unfortunately, unique identifiers such as locus tags are rarely provided in abstracts.

PaperBLAST also incorporates manually-curated protein functions:

Except for GeneRIF and ENA, the curated entries include a short curated description of the protein's function. For entries from BioLiP, the protein's function may not be known beyond binding to the ligand. Many of these entries also link to articles in PubMed.

For more information see the PaperBLAST paper (mSystems 2017) or the code. You can download PaperBLAST's database here.

Changes to PaperBLAST since the paper was written:

Many of these changes are described in Interactive tools for functional annotation of bacterial genomes.

Secrets

PaperBLAST cannot provide snippets for many of the papers that are published in non-open-access journals. This limitation applies even if the paper is marked as "free" on the publisher's web site and is available in PubmedCentral or EuropePMC. If a journal that you publish in is marked as "secret," please consider publishing elsewhere.

Omissions from the PaperBLAST Database

Many important articles are missing from PaperBLAST, either because the article's full text is not in EuropePMC (as for many older articles), or because the paper does not mention a protein identifier such as a locus tag, or because of PaperBLAST's heuristics. If you notice an article that characterizes a protein's function but is missing from PaperBLAST, please notify the curators at UniProt or add an entry to GeneRIF. Entries in either of these databases will eventually be incorporated into PaperBLAST. Note that to add an entry to UniProt, you will need to find the UniProt identifier for the protein. If the protein is not already in UniProt, you can ask them to create an entry. To add an entry to GeneRIF, you will need an NCBI Gene identifier, but unfortunately many prokaryotic proteins in RefSeq do not have corresponding Gene identifers.

References

PaperBLAST: Text-mining papers for information about homologs.
M. N. Price and A. P. Arkin (2017). mSystems, 10.1128/mSystems.00039-17.

Europe PMC in 2017.
M. Levchenko et al (2017). Nucleic Acids Research, 10.1093/nar/gkx1005.

Gene indexing: characterization and analysis of NLM's GeneRIFs.
J. A. Mitchell et al (2003). AMIA Annu Symp Proc 2003:460-464.

UniProt: the universal protein knowledgebase.
The UniProt Consortium (2016). Nucleic Acids Research, 10.1093/nar/gkw1099.

BRENDA in 2017: new perspectives and new tools in BRENDA.
S. Placzek et al (2017). Nucleic Acids Research, 10.1093/nar/gkw952.

The EcoCyc database: reflecting new knowledge about Escherichia coli K-12.
I. M. Keeseler et al (2016). Nucleic Acids Research, 10.1093/nar/gkw1003.

The MetaCyc database of metabolic pathways and enzymes.
R. Caspi et al (2018). Nucleic Acids Research, 10.1093/nar/gkx935.

CharProtDB: a database of experimentally characterized protein annotations.
R. Madupu et al (2012). Nucleic Acids Research, 10.1093/nar/gkr1133.

The carbohydrate-active enzymes database (CAZy) in 2013.
V. Lombard et al (2014). Nucleic Acids Research, 10.1093/nar/gkt1178.

The Transporter Classification Database (TCDB): recent advances
M. H. Saier, Jr. et al (2016). Nucleic Acids Research, 10.1093/nar/gkv1103.

REBASE - a database for DNA restriction and modification: enzymes, genes and genomes.
R. J. Roberts et al (2015). Nucleic Acids Research, 10.1093/nar/gku1046.

Deep annotation of protein function across diverse bacteria from mutant phenotypes.
M. N. Price et al (2016). bioRxiv, 10.1101/072470.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory