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PaperBLAST

PaperBLAST Hits for reanno::pseudo1_N1B4:Pf1N1B4_1109 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) (Pseudomonas fluorescens FW300-N1B4) (481 a.a., VADAKRYDNY...)

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Found 250 similar proteins in the literature:

Pf1N1B4_1109 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas fluorescens FW300-N1B4
100% identity, 100% coverage

PFLU0850 putative aldehyde dehydrogenase from Pseudomonas fluorescens SBW25
93% identity, 100% coverage

PS417_04200 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas simiae WCS417
PS417_04200 aldehyde dehydrogenase family protein from Pseudomonas simiae
93% identity, 100% coverage

Bphyt_5803 Aldehyde Dehydrogenase from Burkholderia phytofirmans PsJN
65% identity, 99% coverage

SAMCCGM7_Ch2624 aldehyde dehydrogenase family protein from Sinorhizobium americanum CCGM7
68% identity, 98% coverage

RL3613 putative aldehyde dehydrogenase from Rhizobium leguminosarum bv. viciae 3841
65% identity, 98% coverage

SM_b20891 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Sinorhizobium meliloti 1021
66% identity, 98% coverage

BAB1_0211 Aldehyde dehydrogenase from Brucella melitensis biovar Abortus 2308
BruAb1_0205 aldehyde dehydrogenase family protein from Brucella abortus biovar 1 str. 9-941
66% identity, 98% coverage

Ac3H11_612 2-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26) from Acidovorax sp. GW101-3H11
62% identity, 98% coverage

PP2694 aldehyde dehydrogenase family protein from Pseudomonas putida KT2440
PP_2694 aldehyde dehydrogenase family protein from Pseudomonas putida KT2440
58% identity, 99% coverage

xylA / A0A0H3C801 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Caulobacter vibrioides (strain NA1000 / CB15N) (see 6 papers)
CC0822, CC_0822 aldehyde dehydrogenase from Caulobacter crescentus CB15
59% identity, 98% coverage

P42329 Aldehyde dehydrogenase, thermostable from Geobacillus stearothermophilus
44% identity, 98% coverage

BLi00285 YcbD from Bacillus licheniformis DSM 13
44% identity, 98% coverage

HWX41_RS19325 aldehyde dehydrogenase family protein from Bacillus paramycoides
43% identity, 99% coverage

alr3771 aldehyde dehydrogenase from Nostoc sp. PCC 7120
41% identity, 95% coverage

KGSDH_BACSU / P42236 Alpha-ketoglutaric semialdehyde dehydrogenase; alphaKGSA dehydrogenase; 2,5-dioxovalerate dehydrogenase; EC 1.2.1.26 from Bacillus subtilis (strain 168) (see 2 papers)
44% identity, 98% coverage

Ava_1554 Aldehyde dehydrogenase from Anabaena variabilis ATCC 29413
40% identity, 95% coverage

xacF / D4GP41 α-ketoglutarate semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see paper)
KGSDH_HALVD / D4GP41 Alpha-ketoglutarate semialdehyde dehydrogenase; KGSADH; EC 1.2.1.26 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase from Haloferax volcanii DS2
43% identity, 98% coverage

MSMEG_6687 aldehyde dehydrogenase, thermostable from Mycobacterium smegmatis str. MC2 155
44% identity, 97% coverage

glr3848 aldehyde dehydrogenase from Gloeobacter violaceus PCC 7421
40% identity, 95% coverage

dopDH / Q97UA1 2,5-dioxopentanoate dehydrogenase subunit (EC 1.2.1.26) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
KGSDH_SACS2 / Q97UA1 2,5-dioxopentanoate dehydrogenase; DopDH; Aldehyde dehydrogenase T; Alpha-ketoglutaric semialdehyde dehydrogenase AldhT; EC 1.2.1.26 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q97UA1 lactaldehyde dehydrogenase (EC 1.2.1.22); 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Saccharolobus solfataricus (see 3 papers)
SSO3117 Aldehyde dehydrogenase (aldhT) from Sulfolobus solfataricus P2
SSO3117 2,5-dioxopentanoate dehydrogenase from Saccharolobus solfataricus P2
41% identity, 98% coverage

Hlac_2240 Aldehyde Dehydrogenase from Halorubrum lacusprofundi ATCC 49239
42% identity, 98% coverage

Saci_1938 aldehyde dehydrogenase from Sulfolobus acidocaldarius DSM 639
41% identity, 97% coverage

rrnAC3036 aldehyde dehydrogenase from Haloarcula marismortui ATCC 43049
41% identity, 99% coverage

Saci_1700 aldehyde dehydrogenase from Sulfolobus acidocaldarius DSM 639
41% identity, 94% coverage

BpOF4_21524 aldehyde dehydrogenase from Bacillus pseudofirmus OF4
39% identity, 98% coverage

SLG_31150 NAD-dependent succinate-semialdehyde dehydrogenase from Sphingobium sp. SYK-6
39% identity, 95% coverage

Trad_2228 aldehyde dehydrogenase family protein from Truepera radiovictrix DSM 17093
38% identity, 90% coverage

WP_013178702 aldehyde dehydrogenase family protein from Truepera radiovictrix
38% identity, 89% coverage

RGM3321_11565 aldehyde dehydrogenase from Pseudomonas sp. RGM 3321
39% identity, 96% coverage

Dret_0129 betaine aldehyde dehydrogenase from Desulfohalobium retbaense DSM 5692
38% identity, 95% coverage

HWX41_RS17225 aldehyde dehydrogenase family protein from Bacillus paramycoides
38% identity, 94% coverage

GK2772 NAD-dependent aldehyde dehydrogenase from Geobacillus kaustophilus HTA426
41% identity, 95% coverage

Q5KEX3 Aldehyde dehydrogenase (Alddh), putative from Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
CNF03900 aldehyde dehydrogenase (alddh) from Cryptococcus neoformans var. neoformans JEC21
39% identity, 93% coverage

Q9FAB1 long-chain-aldehyde dehydrogenase (EC 1.2.1.48) from Geobacillus thermoleovorans (see paper)
40% identity, 96% coverage

SCHCODRAFT_65657 aldehyde dehydrogenase from Schizophyllum commune H4-8
41% identity, 94% coverage

3jz4A / P25526 Crystal structure of e. Coli NADP dependent enzyme (see paper)
38% identity, 99% coverage

Gmet_2131 Aldehyde dehydrogenase from Geobacter metallireducens GS-15
39% identity, 98% coverage

Pc18g02760 uncharacterized protein from Penicillium rubens
39% identity, 88% coverage

Smp_022960 putative aldehyde dehydrogenase from Schistosoma mansoni
40% identity, 91% coverage

Sca_1625 putative aldehyde dehydrogenase family protein from Staphylococcus carnosus subsp. carnosus TM300
B9DMD5 aldehyde dehydrogenase (NAD(+)) from Staphylococcus carnosus (strain TM300)
40% identity, 97% coverage

GabD / b2661 succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
gabD / P25526 succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli (strain K12) (see 22 papers)
GABD_ECOLI / P25526 Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli (strain K12) (see 4 papers)
P25526 succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli K-12 (see paper)
GB|AAC75708.1 succinate-semialdehyde dehydrogenase [NAD(P)+]; EC 1.2.1.16 from Escherichia coli K12 (see 5 papers)
NP_417147 succinate-semialdehyde dehydrogenase (NADP(+)) GabD from Escherichia coli str. K-12 substr. MG1655
b2661 succinate-semialdehyde dehydrogenase I, NADP-dependent from Escherichia coli str. K-12 substr. MG1655
38% identity, 99% coverage

WP_153256127 aldehyde dehydrogenase DhaS from Bacillus subtilis
39% identity, 95% coverage

ALDH4_BACSU / O34660 Putative aldehyde dehydrogenase DhaS; EC 1.2.1.3 from Bacillus subtilis (strain 168) (see paper)
BSU19310 putative aldehyde dehydrogenase from Bacillus subtilis subsp. subtilis str. 168
39% identity, 95% coverage

AS588_RS05800 aldehyde dehydrogenase family protein from Bacillus amyloliquefaciens
39% identity, 95% coverage

WP_105285925 NADP-dependent succinate-semialdehyde dehydrogenase from Escherichia coli
38% identity, 99% coverage

PSPTO0300 succinate-semialdehyde dehydrogenase from Pseudomonas syringae pv. tomato str. DC3000
37% identity, 98% coverage

V529_19360 aldehyde dehydrogenase family protein from Bacillus velezensis SQR9
39% identity, 95% coverage

ECs3522 succinate-semialdehyde dehydrogenase from Escherichia coli O157:H7 str. Sakai
Z3959 succinate-semialdehyde dehydrogenase, NADP-dependent activity from Escherichia coli O157:H7 EDL933
38% identity, 99% coverage

RCF35_14870 aldehyde dehydrogenase family protein from Bacillus velezensis
38% identity, 95% coverage

Q4WPA5 Aldehyde dehydrogenase, putative from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)
Afu4g08600 aldehyde dehydrogenase, putative from Aspergillus fumigatus Af293
38% identity, 85% coverage

SE2166 glycine betaine aldehyde dehydrogenase gbsA from Staphylococcus epidermidis ATCC 12228
36% identity, 94% coverage

AO090023000467 No description from Aspergillus oryzae RIB40
39% identity, 94% coverage

WP_013623073 aldehyde dehydrogenase family protein from Deinococcus proteolyticus MRP
36% identity, 87% coverage

ABC0047 aldehyde dehydrogenase from Bacillus clausii KSM-K16
40% identity, 94% coverage

RBAM_019060 DhaS from Bacillus amyloliquefaciens FZB42
38% identity, 95% coverage

SERP2177 betaine aldehyde dehydrogenase from Staphylococcus epidermidis RP62A
SERP_RS10790 betaine-aldehyde dehydrogenase from Staphylococcus epidermidis RP62A
36% identity, 94% coverage

Q88RC0 glutarate-semialdehyde dehydrogenase (EC 1.2.1.20) from Pseudomonas putida (see 2 papers)
PP0213 succinate-semialdehyde dehydrogenase from Pseudomonas putida KT2440
PP_0213 NADP-dependent succinate-semialdehyde dehydrogenase from Pseudomonas putida KT2440
38% identity, 98% coverage

CNAG_06628 aldehyde dehydrogenase (NAD) from Cryptococcus neoformans var. grubii H99
40% identity, 93% coverage

PSPTO_2673 aldehyde dehydrogenase family protein from Pseudomonas syringae pv. tomato str. DC3000
38% identity, 96% coverage

O74187 Aldehyde dehydrogenase from Agaricus bisporus
37% identity, 94% coverage

PP_3646 aldehyde dehydrogenase family protein from Pseudomonas putida KT2440
38% identity, 96% coverage

FGSG_02273 aldehyde dehydrogenase from Fusarium graminearum PH-1
37% identity, 94% coverage

Cbei_4936 aldehyde dehydrogenase from Clostridium beijerincki NCIMB 8052
38% identity, 95% coverage

OGAPODRAFT_16764 aldehyde dehydrogenase from Ogataea polymorpha
38% identity, 91% coverage

SXYL_00225 betaine-aldehyde dehydrogenase from Staphylococcus xylosus
35% identity, 94% coverage

4neaA / A0A0H2X0S3 1.90 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) from staphylococcus aureus in complex with NAD+ and bme-free cys289 (see paper)
35% identity, 92% coverage

Q9L4P8 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Staphylococcus aureus (see paper)
SACOL2628 betaine aldehyde dehydrogenase from Staphylococcus aureus subsp. aureus COL
SAOUHSC_02933 betaine aldehyde dehydrogenase from Staphylococcus aureus subsp. aureus NCTC 8325
SAUSA300_2546 glycine betaine aldehyde dehydrogenase from Staphylococcus aureus subsp. aureus USA300_FPR3757
MW2532 glycine betaine aldehyde dehydrogenase gbsA from Staphylococcus aureus subsp. aureus MW2
NWMN_2510 glycine betaine aldehyde dehydrogenase from Staphylococcus aureus subsp. aureus str. Newman
CH51_RS14770 betaine-aldehyde dehydrogenase from Staphylococcus aureus
35% identity, 94% coverage

MED193_21681 betaine aldehyde dehydrogenase from Roseobacter sp. MED193
A3XF87 Betaine-aldehyde dehydrogenase from Roseobacter sp. MED193
38% identity, 96% coverage

SAR2691 putative betaine aldehyde dehydrogenase from Staphylococcus aureus subsp. aureus MRSA252
35% identity, 94% coverage

Q6FVP8 Candida glabrata strain CBS138 chromosome D complete sequence from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138)
38% identity, 89% coverage

MAA_02517 aldehyde dehydrogenase from Metarhizium robertsii ARSEF 23
39% identity, 89% coverage

MOC_0592 aldehyde dehydrogenase from Methylobacterium oryzae CBMB20
40% identity, 86% coverage

A0A0D2Y168 Uncharacterized protein from Fusarium oxysporum (strain Fo5176)
37% identity, 94% coverage

An04g03400 uncharacterized protein from Aspergillus niger
38% identity, 94% coverage

SSCH_320003 aldehyde dehydrogenase family protein from Syntrophaceticus schinkii
37% identity, 97% coverage

GYMC52_3134 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase from Geobacillus sp. Y412MC52
37% identity, 94% coverage

A0A0F4THK8 succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) from Pseudomonas fluorescens (see paper)
36% identity, 99% coverage

PFLU0180 succinate-semialdehyde dehydrogenase from Pseudomonas fluorescens SBW25
36% identity, 99% coverage

A2QRU8 Aldehyde dehydrogenase from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
An08g07290 aldehyde dehydrogenase aldA-Aspergillus niger from Aspergillus niger
39% identity, 94% coverage

Marky_1255, WP_013704042 aldehyde dehydrogenase family protein from Marinithermus hydrothermalis DSM 14884
38% identity, 87% coverage

APA386B_1946 aldehyde dehydrogenase from Acetobacter pasteurianus 386B
38% identity, 100% coverage

P41751 Aldehyde dehydrogenase from Aspergillus niger
39% identity, 94% coverage

SAV2613 glycine betaine aldehyde dehydrogenase from Staphylococcus aureus subsp. aureus Mu50
SA2406 glycine betaine aldehyde dehydrogenase gbsA from Staphylococcus aureus subsp. aureus N315
35% identity, 94% coverage

cymC / O33455 cumic aldehyde dehydrogenase (EC 1.2.1.29) from Pseudomonas putida (see paper)
cymc / AAB62298.1 p-cumic aldehyde dehydrogenase from Pseudomonas putida (see 3 papers)
39% identity, 95% coverage

PfGW456L13_495 Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20) from Pseudomonas fluorescens GW456-L13
36% identity, 99% coverage

CND02060 Aldehyde dehydrogenase (ALDDH) from Cryptococcus neoformans var. neoformans JEC21
CNBD4300 hypothetical protein from Cryptococcus neoformans var. neoformans B-3501A
37% identity, 95% coverage

LOC4326376 aldehyde dehydrogenase family 2 member C4 from Oryza sativa Japonica Group
39% identity, 92% coverage

Saci_1857 aldehyde dehydrogenase from Sulfolobus acidocaldarius DSM 639
36% identity, 96% coverage

AWC34_RS13165 aldehyde dehydrogenase family protein from Staphylococcus equorum
36% identity, 95% coverage

Q6FPK0 Candida glabrata strain CBS138 chromosome J complete sequence from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138)
37% identity, 90% coverage

AL1L1_MOUSE / Q8R0Y6 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; EC 1.5.1.6 from Mus musculus (Mouse) (see paper)
38% identity, 52% coverage

ATEG_05020 aldehyde dehydrogenase from Aspergillus terreus NIH2624
39% identity, 94% coverage

LADH / A3LNE3 NAD(P)+ L-lactaldehyde dehydrogenase from Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (see paper)
38% identity, 95% coverage

FGSG_04194 aldehyde dehydrogenase from Fusarium graminearum PH-1
37% identity, 94% coverage

UW3_RS0109265 NADP-dependent succinate-semialdehyde dehydrogenase from Pseudomonas donghuensis
36% identity, 98% coverage

Entcl_0876 NADP-dependent succinate-semialdehyde dehydrogenase from [Enterobacter] lignolyticus SCF1
37% identity, 99% coverage

DV527_RS01175 betaine-aldehyde dehydrogenase from Staphylococcus saprophyticus
36% identity, 94% coverage

7rluA / P28037 Structure of aldh1l1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP (see paper)
37% identity, 81% coverage

XP_011241705 mitochondrial 10-formyltetrahydrofolate dehydrogenase isoform X1 from Mus musculus
38% identity, 59% coverage

AO353_11505 succinate-semialdehyde dehydrogenase (EC 1.2.1.16) from Pseudomonas fluorescens FW300-N2E3
36% identity, 99% coverage

LOC101506901, XP_004488550 succinate-semialdehyde dehydrogenase, mitochondrial from Cicer arietinum
37% identity, 90% coverage

NCU00378 aldehyde dehydrogenase from Neurospora crassa OR74A
38% identity, 86% coverage

HMPREF0010_01350 NAD-dependent succinate-semialdehyde dehydrogenase from Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841
37% identity, 98% coverage

AL1L1_RAT / P28037 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; FBP-CI; EC 1.5.1.6 from Rattus norvegicus (Rat) (see 7 papers)
P28037 formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) from Rattus norvegicus (see 3 papers)
NP_071992 cytosolic 10-formyltetrahydrofolate dehydrogenase from Rattus norvegicus
37% identity, 52% coverage

HWX41_RS06485 aldehyde dehydrogenase DhaS from Bacillus paramycoides
38% identity, 95% coverage

ZP_01726360 aldehyde dehydrogenase from Cyanothece sp. CCY 0110
39% identity, 95% coverage

D3Z6B9 formyltetrahydrofolate dehydrogenase from Mus musculus
38% identity, 58% coverage

AWY96_RS13985 aldehyde dehydrogenase family protein from Serratia plymuthica
38% identity, 95% coverage

VDAG_06372 aldehyde dehydrogenase from Verticillium dahliae VdLs.17
38% identity, 93% coverage

FOXG_00928 aldehyde dehydrogenase from Fusarium oxysporum f. sp. lycopersici 4287
38% identity, 95% coverage

CNAG_01078 aldehyde dehydrogenase (NAD) from Cryptococcus neoformans var. grubii H99
37% identity, 95% coverage

Q9CZS1 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Mus musculus (see 2 papers)
NP_082546 aldehyde dehydrogenase X, mitochondrial precursor from Mus musculus
39% identity, 91% coverage

PGTG_15008 aldehyde dehydrogenase (NAD+) from Puccinia graminis f. sp. tritici CRL 75-36-700-3
39% identity, 94% coverage

AL1L2_MOUSE / Q8K009 Mitochondrial 10-formyltetrahydrofolate dehydrogenase; Mitochondrial 10-FTHFDH; mtFDH; Aldehyde dehydrogenase family 1 member L2; EC 1.5.1.6 from Mus musculus (Mouse) (see paper)
38% identity, 51% coverage

davD / Q9I6M5 glutarate semialdehyde dehydrogenase (EC 1.2.1.20) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
DAVD_PSEAE / Q9I6M5 Glutarate-semialdehyde dehydrogenase; EC 1.2.1.- from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
PA0265 succinate-semialdehyde dehydrogenase from Pseudomonas aeruginosa PAO1
36% identity, 99% coverage

LOC541914, NP_001105047 aldehyde dehydrogenase 5 from Zea mays
Q8S529 Aldehyde dehydrogenase5 from Zea mays
40% identity, 91% coverage

BAS3348 aldehyde dehydrogenase from Bacillus anthracis str. Sterne
BA3609 aldehyde dehydrogenase from Bacillus anthracis str. Ames
GBAA3609 aldehyde dehydrogenase from Bacillus anthracis str. 'Ames Ancestor'
38% identity, 95% coverage

BC3555 Aldehyde dehydrogenase from Bacillus cereus ATCC 14579
37% identity, 95% coverage

G3V7I5 Aldehyde dehydrogenase X, mitochondrial from Rattus norvegicus
39% identity, 91% coverage

P30837 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Homo sapiens (see 2 papers)
NP_000683 aldehyde dehydrogenase X, mitochondrial precursor from Homo sapiens
38% identity, 91% coverage

7mjcA / P30837 Crystal structure analysis of aldh1b1
38% identity, 95% coverage

8rwkA / P46367 Cryoem structure of the central ald4 filament determined by filamentid (see paper)
39% identity, 91% coverage

FOXG_11443 aldehyde dehydrogenase (NAD+) from Fusarium oxysporum f. sp. lycopersici 4287
37% identity, 84% coverage

E4T72_11990 aldehyde dehydrogenase family protein from Staphylococcus xylosus
39% identity, 97% coverage

ALD6 / P54115 magnesium-activated aldehyde dehydrogenase, cytosolic (EC 1.2.1.4) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
ALDH6_YEAST / P54115 Magnesium-activated aldehyde dehydrogenase, cytosolic; Mg(2+)-activated acetaldehyde dehydrogenase; Mg(2+)-ACDH; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P54115 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3); aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) from Saccharomyces cerevisiae (see 2 papers)
NP_015264 aldehyde dehydrogenase (NADP(+)) ALD6 from Saccharomyces cerevisiae S288C
YPL061W Ald6p from Saccharomyces cerevisiae
37% identity, 93% coverage

FGSG_02160 aldehyde dehydrogenase from Fusarium graminearum PH-1
37% identity, 97% coverage

ALD4 / P46367 potassium-activated aldehyde dehydrogenase, mitochondrial (EC 1.2.1.4; EC 1.2.1.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
ALDH4_YEAST / P46367 Potassium-activated aldehyde dehydrogenase, mitochondrial; K(+)-activated acetaldehyde dehydrogenase; K(+)-ACDH; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
P46367 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Saccharomyces cerevisiae (see paper)
NP_015019 aldehyde dehydrogenase (NADP(+)) ALD4 from Saccharomyces cerevisiae S288C
YOR374W Ald4p from Saccharomyces cerevisiae
39% identity, 87% coverage

Rmet_4942 succinate-semialdehyde dehydrogenase I, NADP-dependent from Ralstonia metallidurans CH34
Rmet_4942 NAD-dependent succinate-semialdehyde dehydrogenase from Cupriavidus metallidurans CH34
38% identity, 97% coverage

NP_695212 retinaldehyde dehydrogenase 3 from Rattus norvegicus
39% identity, 92% coverage

F7H5N9 Aldehyde dehydrogenase X, mitochondrial from Macaca mulatta
38% identity, 91% coverage

Q8K4D8 retinal dehydrogenase (EC 1.2.1.36) from Rattus norvegicus (see paper)
39% identity, 92% coverage

A9EEP5 Aldehyde dehydrogenase family 1 subfamily A3 from Rattus norvegicus
39% identity, 92% coverage

hpaE / Q46979 subunit of 5-carboxymethyl-2-hydroxymuconic semialdehyde dehydrogenase (EC 1.2.1.60) from Escherichia coli (see 2 papers)
37% identity, 97% coverage

SSDH_ARATH / Q9SAK4 Succinate-semialdehyde dehydrogenase, mitochondrial; At-SSADH1; Aldehyde dehydrogenase family 5 member F1; NAD(+)-dependent succinic semialdehyde dehydrogenase; Protein ENLARGED FIL EXPRESSING DOMAIN 1; EC 1.2.1.24 from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
AT1G79440 ALDH5F1; 3-chloroallyl aldehyde dehydrogenase/ NAD or NADH binding / succinate-semialdehyde dehydrogenase from Arabidopsis thaliana
NP_178062 aldehyde dehydrogenase 5F1 from Arabidopsis thaliana
37% identity, 90% coverage

BU104_12250 aldehyde dehydrogenase family protein from Staphylococcus xylosus
39% identity, 97% coverage

C1LFP4 Putative aldehyde dehydrogenase 1B1 from Schistosoma japonicum
38% identity, 95% coverage

Bxe_B2030 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase (HpaE) from Burkholderia xenovorans LB400
Bxe_B2030 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase from Paraburkholderia xenovorans LB400
37% identity, 96% coverage

Q66HF8 Aldehyde dehydrogenase X, mitochondrial from Rattus norvegicus
38% identity, 91% coverage

AL1A3_MOUSE / Q9JHW9 Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; Aldh1a3; EC 1.2.1.36 from Mus musculus (Mouse) (see 7 papers)
Q9JHW9 retinal dehydrogenase (EC 1.2.1.36); aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Mus musculus (see 4 papers)
NP_444310 retinaldehyde dehydrogenase 3 from Mus musculus
39% identity, 92% coverage

Q5R6B5 Aldehyde dehydrogenase X, mitochondrial from Pongo abelii
38% identity, 91% coverage

SC1052 4-hydroxyphenylacetate catabolism from Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
36% identity, 97% coverage

F7HB04 10-formyltetrahydrofolate dehydrogenase from Macaca mulatta
38% identity, 49% coverage

4pz2B / W8SZG1 Structure of zm aldh2-6 (rf2f) in complex with NAD (see paper)
40% identity, 95% coverage

Q8CNI5 Putative aldehyde dehydrogenase SE_1720 from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)
Q5HMA0 Putative aldehyde dehydrogenase SERP1729 from Staphylococcus epidermidis (strain ATCC 35984 / DSM 28319 / BCRC 17069 / CCUG 31568 / BM 3577 / RP62A)
SERP1729 aldehyde dehydrogenase from Staphylococcus epidermidis RP62A
37% identity, 97% coverage

FRAAL0200 NAD+-dependent aldehyde dehydrogenase from Frankia alni ACN14a
37% identity, 91% coverage

NP_001257293 cytosolic 10-formyltetrahydrofolate dehydrogenase isoform 1 from Homo sapiens
39% identity, 51% coverage

ALDH1L1 / O75891 10-formyltetrahydrofolate dehydrogenase 1 (EC 3.5.1.10; EC 1.5.1.6) from Homo sapiens (see 7 papers)
AL1L1_HUMAN / O75891 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; EC 1.5.1.6 from Homo sapiens (Human) (see 3 papers)
O75891 formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) from Homo sapiens (see paper)
39% identity, 52% coverage

LOC18031917 succinate-semialdehyde dehydrogenase, mitochondrial from Citrus x clementina
36% identity, 90% coverage

XP_002939310 aldehyde dehydrogenase family 1 member A3 from Xenopus tropicalis
39% identity, 92% coverage

SPSK_00262 aldehyde dehydrogenase (NAD+) from Sporothrix schenckii 1099-18
38% identity, 95% coverage

KPHS_06330 4-hydroxyphenylacetate catabolism from Klebsiella pneumoniae subsp. pneumoniae HS11286
36% identity, 97% coverage

gabD / Q4KKA2 NAD(P)-dependent succinate-semialdehyde dehydrogenase (EC 1.2.1.16) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
35% identity, 99% coverage

Q5RF00 Aldehyde dehydrogenase, mitochondrial from Pongo abelii
NP_001124747 aldehyde dehydrogenase, mitochondrial precursor from Pongo abelii
39% identity, 90% coverage

rrnAC2473 aldehyde dehydrogenase from Haloarcula marismortui ATCC 43049
36% identity, 88% coverage

4fr8C / P05091 Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin (see paper)
39% identity, 94% coverage

LOC116940317 retinal dehydrogenase 2-like from Petromyzon marinus
39% identity, 91% coverage

BRA1161 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase from Brucella suis 1330
39% identity, 93% coverage

CwatDRAFT_0842 Aldehyde dehydrogenase (NAD+) from Crocosphaera watsonii WH 8501
39% identity, 95% coverage

ALDH2 / P05091 mitochondrial aldehyde dehydrogenase subunit (EC 1.2.1.3; EC 1.2.1.39) from Homo sapiens (see 14 papers)
ALDH2_HUMAN / P05091 Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDHI; EC 1.2.1.3 from Homo sapiens (Human) (see 3 papers)
P05091 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Homo sapiens (see 13 papers)
NP_000681 aldehyde dehydrogenase, mitochondrial isoform 1 precursor from Homo sapiens
39% identity, 90% coverage

ALD5 / P40047 aldehyde dehydrogenase, mitochondrial (EC 1.2.1.4; EC 1.2.1.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
ALDH5_YEAST / P40047 Aldehyde dehydrogenase 5, mitochondrial; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
NP_010996 aldehyde dehydrogenase (NAD(P)(+)) ALD5 from Saccharomyces cerevisiae S288C
37% identity, 90% coverage

Q0QHK6 1-pyrroline-5-carboxylate dehydrogenase 2 from Glossina morsitans morsitans
38% identity, 89% coverage

NP_010996, YER073W Ald5p from Saccharomyces cerevisiae
37% identity, 90% coverage

Entcl_3798 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase from [Enterobacter] lignolyticus SCF1
36% identity, 97% coverage

TGNE_ACIAD / Q6F9G0 Succinate semialdehyde dehydrogenase; SSA dehydrogenase; EC 1.2.1.24 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
ACIAD2539 succinate-semialdehyde dehydrogenase from Acinetobacter sp. ADP1
35% identity, 98% coverage

BADH_SPIOL / P17202 Aminoaldehyde dehydrogenase BADH; 4-trimethylammoniobutyraldehyde dehydrogenase BADH; Aminobutyraldehyde dehydrogenase BADH; Betaine aldehyde dehydrogenase; SoBADH; EC 1.2.1.-; EC 1.2.1.47; EC 1.2.1.19; EC 1.2.1.8 from Spinacia oleracea (Spinach) (see 5 papers)
P17202 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Spinacia oleracea (see 3 papers)
35% identity, 94% coverage

Q6C7J6 YALI0E00264p from Yarrowia lipolytica (strain CLIB 122 / E 150)
38% identity, 89% coverage

AFUA_7G01000, Afu7g01000 aldehyde dehydrogenase, putative from Aspergillus fumigatus Af293
37% identity, 95% coverage

XP_002322147 aminoaldehyde dehydrogenase 2, peroxisomal from Populus trichocarpa
35% identity, 93% coverage

BCAM0469 putative aldehyde dehydrogenase from Burkholderia cenocepacia J2315
36% identity, 96% coverage

Tery_2599 Aldehyde dehydrogenase (NAD+) from Trichodesmium erythraeum IMS101
38% identity, 95% coverage

Q53FB6 Aldehyde dehydrogenase, mitochondrial (Fragment) from Homo sapiens
39% identity, 90% coverage

4o6rA / B4EJX1 Crystal structure of a putative aldehyde dehydrogenase from burkholderia cenocepacia
36% identity, 96% coverage

HD73_3146 aldehyde dehydrogenase family protein from Bacillus thuringiensis serovar kurstaki str. HD73
36% identity, 95% coverage

G7PIP6 Aldehyde dehydrogenase, mitochondrial from Macaca fascicularis
39% identity, 90% coverage

PAS_chr4_0043 Mitochondrial aldehyde dehydrogenase from Komagataella phaffii GS115
C4R6P6 Mitochondrial aldehyde dehydrogenase from Komagataella phaffii (strain GS115 / ATCC 20864)
F2R0E4 Magnesium-activated aldehyde dehydrogenase, cytosolic from Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1)
38% identity, 93% coverage

betB / P54222 betaine aldehyde dehydrogenase (EC 1.2.1.8) from Rhizobium meliloti (strain 1021) (see 2 papers)
SMc00094 BETAINE ALDEHYDE DEHYDROGENASE BADH OXIDOREDUCTASE NAD PROTEIN from Sinorhizobium meliloti 1021
38% identity, 98% coverage

Q6C2W9 YALI0F04444p from Yarrowia lipolytica (strain CLIB 122 / E 150)
38% identity, 91% coverage

2d4eC / Q5SJP9 Crystal structure of the hpcc from thermus thermophilus hb8
37% identity, 91% coverage

D0Z05_13800 NAD-dependent succinate-semialdehyde dehydrogenase from Enterobacter hormaechei
36% identity, 97% coverage

pRL120044 succinate-semialdehyde dehydrogenase (NADP+) from Rhizobium leguminosarum bv. viciae 3841
38% identity, 94% coverage

AL1A1_RABIT / Q8MI17 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Oryctolagus cuniculus (Rabbit) (see paper)
39% identity, 94% coverage

blr3954 methylmalonate-semialdehyde dehydrogenase from Bradyrhizobium japonicum USDA 110
Q89N88 methylmalonate-semialdehyde dehydrogenase (CoA acylating) from Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)
37% identity, 94% coverage

UW3_RS0108160 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase from Pseudomonas donghuensis
38% identity, 97% coverage

ALDH1L2 / Q3SY69 10-formyltetrahydrofolate dehydrogenase 2 (EC 3.5.1.10; EC 1.5.1.6) from Homo sapiens (see 4 papers)
AL1L2_HUMAN / Q3SY69 Mitochondrial 10-formyltetrahydrofolate dehydrogenase; Mitochondrial 10-FTHFDH; mtFDH; Aldehyde dehydrogenase family 1 member L2; EC 1.5.1.6 from Homo sapiens (Human) (see 3 papers)
Q3SY69 formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) from Homo sapiens (see paper)
37% identity, 51% coverage

HP15_3144 Aldehyde dehydrogenase (EC 1.2.1.3) from Marinobacter adhaerens HP15
37% identity, 90% coverage

Q5RFM9 Cytosolic 10-formyltetrahydrofolate dehydrogenase from Pongo abelii
39% identity, 52% coverage

BC2832 Aldehyde dehydrogenase from Bacillus cereus ATCC 14579
Q81CE0 Aldehyde dehydrogenase from Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)
36% identity, 95% coverage

Q5K8N2 Aldehyde dehydrogenase (ALDDH), putative from Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
36% identity, 90% coverage

AL1A1_SHEEP / P51977 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Ovis aries (Sheep) (see 2 papers)
39% identity, 94% coverage

NCU03415 aldehyde dehydrogenase from Neurospora crassa OR74A
37% identity, 95% coverage

SAB2006c aldehyde dehydrogenase from Staphylococcus aureus RF122
38% identity, 97% coverage

YLX7_SCHPO / Q9URW9 Putative aldehyde dehydrogenase-like protein C922.07c; EC 1.2.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
SPAC922.07c aldehyde dehydrogenase (predicted) from Schizosaccharomyces pombe
36% identity, 95% coverage

GNP06_05115 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase from Pseudomonas sp. TDA1
38% identity, 97% coverage

BLJAPNOD_03725 betaine-aldehyde dehydrogenase from Ensifer sp. M14
38% identity, 97% coverage

Q0H2G3 retinal dehydrogenase (EC 1.2.1.36) from Danio rerio (see paper)
NP_001038210 aldehyde dehydrogenase family 1 member A3 from Danio rerio
38% identity, 93% coverage

AL1A7_MOUSE / O35945 Aldehyde dehydrogenase, cytosolic 1; ALDH class 1; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A7; Aldehyde dehydrogenase phenobarbital-inducible; EC 1.2.1.3 from Mus musculus (Mouse) (see paper)
O35945 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Mus musculus (see paper)
B2RTL5 Aldehyde dehydrogenase family 1, subfamily A7 from Mus musculus
38% identity, 93% coverage

S4S7H4 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Atriplex canescens (see paper)
35% identity, 93% coverage

RHE_RS28200 NAD-dependent succinate-semialdehyde dehydrogenase from Rhizobium etli CFN 42
36% identity, 98% coverage

5abmA / P51977 Sheep aldehyde dehydrogenase 1a1 (see paper)
39% identity, 95% coverage

Q3U6I3 Aldehyde dehydrogenase, mitochondrial from Mus musculus
39% identity, 90% coverage

gbsA / P71016 betaine aldehyde dehydrogenase subunit (EC 1.2.1.8) from Bacillus subtilis (strain 168) (see paper)
GBSA_BACSU / P71016 Betaine aldehyde dehydrogenase; BADH; Glycine betaine aldehyde dehydrogenase; EC 1.2.1.8 from Bacillus subtilis (strain 168) (see 4 papers)
BSU31060 glycine betaine aldehyde dehydrogenase, NAD+-dependent from Bacillus subtilis subsp. subtilis str. 168
36% identity, 96% coverage

BTH_RS10850 NADP-dependent succinate-semialdehyde dehydrogenase from Burkholderia thailandensis E264
Q2T3E1 Succinate-semialdehyde dehydrogenase from Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CCUG 48851 / CIP 106301 / E264)
37% identity, 96% coverage

B8AIJ7 Aldehyde dehydrogenase from Oryza sativa subsp. indica
35% identity, 90% coverage

GKP31 glycine betaine aldehyde dehydrogenase from Geobacillus kaustophilus HTA426
37% identity, 93% coverage

sll1561 delta-1-pyrroline-5-carboxylate dehydrogenase from Synechocystis sp. PCC 6803
37% identity, 46% coverage

Sb10g023000 No description from Sorghum bicolor
39% identity, 90% coverage

FGSG_00979 aldehyde dehydrogenase from Fusarium graminearum PH-1
37% identity, 96% coverage

Q69XE0 Cytosolic aldehyde dehydrogenase from Oryza sativa subsp. japonica
38% identity, 90% coverage

SAR_RS11525 aldehyde dehydrogenase family protein from Staphylococcus aureus subsp. aureus MRSA252
SAR2210 aldehyde dehydrogenase family protein from Staphylococcus aureus subsp. aureus MRSA252
38% identity, 97% coverage

A0R5S7 Aldehyde dehydrogenase from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
MSMEG_6297 aldehyde dehydrogenase from Mycobacterium smegmatis str. MC2 155
39% identity, 82% coverage

B9F3B6 Succinate-semialdehyde dehydrogenase, mitochondrial from Oryza sativa subsp. japonica
35% identity, 90% coverage

Smp_050390 aldehyde dehydrogenase,putative from Schistosoma mansoni
G4LWI3 Aldehyde dehydrogenase,putative from Schistosoma mansoni
37% identity, 95% coverage

SAUSA300_2076 aldehyde dehydrogenase family protein from Staphylococcus aureus subsp. aureus USA300_FPR3757
SA1924 hypothetical protein from Staphylococcus aureus subsp. aureus N315
SAV2122 aldehyde dehydrogenase from Staphylococcus aureus subsp. aureus Mu50
NWMN_2026 aldehyde dehydrogenase family protein from Staphylococcus aureus subsp. aureus str. Newman
USA300HOU_2110 aldehyde dehydrogenase from Staphylococcus aureus subsp. aureus USA300_TCH1516
SACOL2114 aldehyde dehydrogenase from Staphylococcus aureus subsp. aureus COL
38% identity, 97% coverage

Q155V4 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda salsa (see paper)
Q8W5A1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda liaotungensis (see 2 papers)
35% identity, 93% coverage

5gtkA NAD+ complex structure of aldehyde dehydrogenase from bacillus cereus
36% identity, 96% coverage

4v37A / P17202 Crystal structure of betaine aldehyde dehydrogenase from spinach showing a thiohemiacetal with 3-aminopropionaldehyde
34% identity, 94% coverage

YPK_2459 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase from Yersinia pseudotuberculosis YPIII
35% identity, 97% coverage

NP_001068835 aldehyde dehydrogenase, mitochondrial precursor from Bos taurus
P20000 Aldehyde dehydrogenase, mitochondrial from Bos taurus
38% identity, 90% coverage

lmo0383 highly similar to B. subtilis methylmalonate-semialdehyde dehydrogenase IolA from Listeria monocytogenes EGD-e
36% identity, 97% coverage

AL1A1_BOVIN / P48644 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Bos taurus (Bovine) (see paper)
39% identity, 94% coverage

P27463 retinal dehydrogenase (EC 1.2.1.36) from Gallus gallus (see 2 papers)
39% identity, 92% coverage

LMOf2365_0395 methylmalonate-semialdehyde dehydrogenase from Listeria monocytogenes str. 4b F2365
36% identity, 97% coverage

LOC114357983 aldehyde dehydrogenase X, mitochondrial-like from Ostrinia furnacalis
38% identity, 96% coverage

XP_623084 aldehyde dehydrogenase, mitochondrial from Apis mellifera
39% identity, 92% coverage

mmsA / P42412 (methyl)malonate-semialdehyde dehydrogenase monomer (EC 1.2.1.27; EC 1.2.1.18) from Bacillus subtilis (strain 168) (see 4 papers)
IOLA_BACSU / P42412 Malonate-semialdehyde dehydrogenase; MSA dehydrogenase; Methylmalonate-semialdehyde dehydrogenase; MMSA dehydrogenase; MMSDH; MSDH; EC 1.2.1.27 from Bacillus subtilis (strain 168) (see 5 papers)
P42412 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Bacillus subtilis (see paper)
NP_391855 methylmalonate-semialdehyde dehydrogenase from Bacillus subtilis subsp. subtilis str. 168
35% identity, 97% coverage

PSHAb0219 aldehyde dehydrogenase family protein from Pseudoalteromonas translucida
36% identity, 93% coverage

P81178 Aldehyde dehydrogenase, mitochondrial from Mesocricetus auratus
39% identity, 94% coverage

P47738 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Mus musculus (see 4 papers)
Q544B1 Aldehyde dehydrogenase, mitochondrial from Mus musculus
NP_033786 aldehyde dehydrogenase, mitochondrial isoform 1 precursor from Mus musculus
39% identity, 90% coverage

PA4123 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase from Pseudomonas aeruginosa PAO1
38% identity, 97% coverage

Q3UJW1 Aldehyde dehydrogenase, mitochondrial from Mus musculus
39% identity, 90% coverage

PA14_10630 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase from Pseudomonas aeruginosa UCBPP-PA14
38% identity, 97% coverage

Q3U9J7 Aldehyde dehydrogenase, mitochondrial from Mus musculus
39% identity, 90% coverage

XP_001373128 aldehyde dehydrogenase 1A1 from Monodelphis domestica
39% identity, 91% coverage

Q9KR28 Aldehyde dehydrogenase from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
VC1819 aldehyde dehydrogenase from Vibrio cholerae O1 biovar eltor str. N16961
MS6_1586 aldehyde dehydrogenase family protein from Vibrio cholerae MS6
38% identity, 94% coverage

7a6qA / P47895 Crystal structure of human aldehyde dehydrogenase 1a3 in complex with selective nr6 inhibitor compound (see paper)
37% identity, 96% coverage

Q6TH48 Aldehyde dehydrogenase, mitochondrial from Danio rerio
39% identity, 91% coverage

HD73_0368 NADP-dependent succinate-semialdehyde dehydrogenase from Bacillus thuringiensis serovar kurstaki str. HD73
34% identity, 98% coverage

BAA13145 / Q47943 L-sorbosone dehydrogenase subunit from Gluconobacter oxydans (see paper)
37% identity, 95% coverage

T1FVK5 Aldehyde dehydrogenase domain-containing protein from Helobdella robusta
37% identity, 91% coverage

I3LRS5 aldehyde dehydrogenase (NAD(+)) from Sus scrofa
38% identity, 94% coverage

ALDH1A3 / P47895 retinal dehydrogenase 3 (EC 1.2.1.36) from Homo sapiens (see 3 papers)
AL1A3_HUMAN / P47895 Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; ALDH1A3; EC 1.2.1.36 from Homo sapiens (Human) (see 9 papers)
P47895 retinal dehydrogenase (EC 1.2.1.36); aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Homo sapiens (see 6 papers)
NP_000684 retinaldehyde dehydrogenase 3 isoform 1 from Homo sapiens
37% identity, 92% coverage

BC1G_06362 hypothetical protein from Botrytis cinerea B05.10
37% identity, 95% coverage

Q2F5Y9 Mitochondrial aldehyde dehydrogenase from Bombyx mori
38% identity, 97% coverage

ACIAD1009 NAD+-dependent betaine aldehyde dehydrogenase from Acinetobacter sp. ADP1
36% identity, 97% coverage

I1U3B9 Aldehyde dehydrogenase 1 family member L1 (Fragment) from Ovis aries
40% identity, 81% coverage

7w5nA / Q47943 The crystal structure of the reduced form of gluconobacter oxydans wsh-004 sndh (see paper)
37% identity, 97% coverage

DW66_3578 aldehyde dehydrogenase family protein from Pseudomonas putida
37% identity, 91% coverage

NP_776664 aldehyde dehydrogenase 1A1 from Bos taurus
39% identity, 94% coverage

U3IF86 Aldehyde dehydrogenase from Anas platyrhynchos platyrhynchos
38% identity, 92% coverage

New Search

For advice on how to use these tools together, see Interactive tools for functional annotation of bacterial genomes.

Statistics

The PaperBLAST database links 784,739 different protein sequences to 1,253,012 scientific articles. Searches against EuropePMC were last performed on November 25 2024.

How It Works

PaperBLAST builds a database of protein sequences that are linked to scientific articles. These links come from automated text searches against the articles in EuropePMC and from manually-curated information from GeneRIF, UniProtKB/Swiss-Prot, BRENDA, CAZy (as made available by dbCAN), BioLiP, CharProtDB, MetaCyc, EcoCyc, TCDB, REBASE, the Fitness Browser, and a subset of the European Nucleotide Archive with the /experiment tag. Given this database and a protein sequence query, PaperBLAST uses protein-protein BLAST to find similar sequences with E < 0.001.

To build the database, we query EuropePMC with locus tags, with RefSeq protein identifiers, and with UniProt accessions. We obtain the locus tags from RefSeq or from MicrobesOnline. We use queries of the form "locus_tag AND genus_name" to try to ensure that the paper is actually discussing that gene. Because EuropePMC indexes most recent biomedical papers, even if they are not open access, some of the links may be to papers that you cannot read or that our computers cannot read. We query each of these identifiers that appears in the open access part of EuropePMC, as well as every locus tag that appears in the 500 most-referenced genomes, so that a gene may appear in the PaperBLAST results even though none of the papers that mention it are open access. We also incorporate text-mined links from EuropePMC that link open access articles to UniProt or RefSeq identifiers. (This yields some additional links because EuropePMC uses different heuristics for their text mining than we do.)

For every article that mentions a locus tag, a RefSeq protein identifier, or a UniProt accession, we try to select one or two snippets of text that refer to the protein. If we cannot get access to the full text, we try to select a snippet from the abstract, but unfortunately, unique identifiers such as locus tags are rarely provided in abstracts.

PaperBLAST also incorporates manually-curated protein functions:

Except for GeneRIF and ENA, the curated entries include a short curated description of the protein's function. For entries from BioLiP, the protein's function may not be known beyond binding to the ligand. Many of these entries also link to articles in PubMed.

For more information see the PaperBLAST paper (mSystems 2017) or the code. You can download PaperBLAST's database here.

Changes to PaperBLAST since the paper was written:

Many of these changes are described in Interactive tools for functional annotation of bacterial genomes.

Secrets

PaperBLAST cannot provide snippets for many of the papers that are published in non-open-access journals. This limitation applies even if the paper is marked as "free" on the publisher's web site and is available in PubmedCentral or EuropePMC. If a journal that you publish in is marked as "secret," please consider publishing elsewhere.

Omissions from the PaperBLAST Database

Many important articles are missing from PaperBLAST, either because the article's full text is not in EuropePMC (as for many older articles), or because the paper does not mention a protein identifier such as a locus tag, or because of PaperBLAST's heuristics. If you notice an article that characterizes a protein's function but is missing from PaperBLAST, please notify the curators at UniProt or add an entry to GeneRIF. Entries in either of these databases will eventually be incorporated into PaperBLAST. Note that to add an entry to UniProt, you will need to find the UniProt identifier for the protein. If the protein is not already in UniProt, you can ask them to create an entry. To add an entry to GeneRIF, you will need an NCBI Gene identifier, but unfortunately many prokaryotic proteins in RefSeq do not have corresponding Gene identifers.

References

PaperBLAST: Text-mining papers for information about homologs.
M. N. Price and A. P. Arkin (2017). mSystems, 10.1128/mSystems.00039-17.

Europe PMC in 2017.
M. Levchenko et al (2017). Nucleic Acids Research, 10.1093/nar/gkx1005.

Gene indexing: characterization and analysis of NLM's GeneRIFs.
J. A. Mitchell et al (2003). AMIA Annu Symp Proc 2003:460-464.

UniProt: the universal protein knowledgebase.
The UniProt Consortium (2016). Nucleic Acids Research, 10.1093/nar/gkw1099.

BRENDA in 2017: new perspectives and new tools in BRENDA.
S. Placzek et al (2017). Nucleic Acids Research, 10.1093/nar/gkw952.

The EcoCyc database: reflecting new knowledge about Escherichia coli K-12.
I. M. Keeseler et al (2016). Nucleic Acids Research, 10.1093/nar/gkw1003.

The MetaCyc database of metabolic pathways and enzymes.
R. Caspi et al (2018). Nucleic Acids Research, 10.1093/nar/gkx935.

CharProtDB: a database of experimentally characterized protein annotations.
R. Madupu et al (2012). Nucleic Acids Research, 10.1093/nar/gkr1133.

The carbohydrate-active enzymes database (CAZy) in 2013.
V. Lombard et al (2014). Nucleic Acids Research, 10.1093/nar/gkt1178.

The Transporter Classification Database (TCDB): recent advances
M. H. Saier, Jr. et al (2016). Nucleic Acids Research, 10.1093/nar/gkv1103.

REBASE - a database for DNA restriction and modification: enzymes, genes and genomes.
R. J. Roberts et al (2015). Nucleic Acids Research, 10.1093/nar/gku1046.

Deep annotation of protein function across diverse bacteria from mutant phenotypes.
M. N. Price et al (2016). bioRxiv, 10.1101/072470.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory