queryId subjectDb subjectId identity queryAlnBegin queryAlnEnd sujectAlnBegin subjectAlnEnd subjectDescription evalue bits subjectSite subjectSiteRange subjectSiteSeq querySiteRange querySiteSeq pubMedIds GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 active site 100 L 99 L 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 active site 241 R 237 R 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 active site 265 D 261 D 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 active site 270 E 266 E 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 active site 288 H 285 H 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding glyoxylic acid 74 Y 73 V 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding glyoxylic acid 75 A 74 S 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding glyoxylic acid 76 V 75 V 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding glyoxylic acid 77 G 76 G 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding glyoxylic acid 241 R 237 R 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding glyoxylic acid 288 H 285 H 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 76 V 75 V 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 104 T 103 T 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 158 F 153 M 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 159 G 154 G 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 160 R 155 R 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 161 I 156 I 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 180 S 176 S 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 181 R 177 H 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 211 A 207 T 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 212 V 208 L 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 213 P 209 P 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 218 T 214 T 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 239 I 235 I 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 240 A 236 S 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 241 R 237 R 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 288 H 285 H 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding nadp nicotinamide-adenine-dinucleotide phosphate 290 G 287 G 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding glyoxylic acid 52 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding glyoxylic acid 53 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5aov:A 49.1 53 319 54 322 Ternary crystal structure of pyrococcus furiosus glyoxylate hydroxypyruvate reductase in presence of glyoxylate 7e-68 255 binding glyoxylic acid 53 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 active site 99 L 99 L 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 active site 240 R 237 R 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 active site 264 D 261 D 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 active site 269 E 266 E 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 active site 287 H 285 H 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 75 V 75 V 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 103 T 103 T 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 156 G 152 G 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 157 F 153 M 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 158 G 154 G 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 159 R 155 R 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 160 I 156 I 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 179 A 176 S 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 180 R 177 H 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 181 S 178 S 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 183 K 180 K 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 211 V 208 L 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 212 P 209 P 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 216 E 213 E 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 217 T 214 T 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 238 V 235 I 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 239 A 236 S 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 240 R 237 R 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 264 D 261 D 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 287 H 285 H 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6bii:A 48.7 53 319 53 321 Crystal structure of pyrococcus yayanosii glyoxylate hydroxypyruvate reductase in complex with NADP and malonate (re-refinement of 5aow) 2e-61 234 binding nadp nicotinamide-adenine-dinucleotide phosphate 289 G 287 G 26865263 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 active site 100 L 99 L 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 active site 241 R 237 R 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 active site 265 D 261 D 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 active site 270 E 266 E 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 active site 288 H 285 H 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 76 V 75 V 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 104 T 103 T 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 158 L 153 M 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 159 G 154 G 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 160 R 155 R 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 161 I 156 I 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 180 S 176 S 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 181 R 177 H 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 182 T 178 S 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 211 A 207 T 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 212 V 208 L 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 213 P 209 P 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 218 T 214 T 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 239 I 235 I 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 240 A 236 S 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 241 R 237 R 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 265 D 261 D 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 288 H 285 H 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2dbq:A 50.6 53 319 54 322 Crystal structure of glyoxylate reductase (ph0597) from pyrococcus horikoshii ot3, complexed with NADP (i41) 3e-54 210 binding nadp nicotinamide-adenine-dinucleotide phosphate 290 G 287 G 17327673 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GYAR_PYRHO 50.6 53 319 54 322 Glyoxylate reductase; EC 1.1.1.26 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) 3e-54 210 binding 158..161 LGRI 153..156 MGRI GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GYAR_PYRHO 50.6 53 319 54 322 Glyoxylate reductase; EC 1.1.1.26 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) 3e-54 210 binding 180..182 SRT 176..178 SHS GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GYAR_PYRHO 50.6 53 319 54 322 Glyoxylate reductase; EC 1.1.1.26 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) 3e-54 210 binding 239..241 IAR 235..237 ISR GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GYAR_PYRHO 50.6 53 319 54 322 Glyoxylate reductase; EC 1.1.1.26 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) 3e-54 210 binding 288..290 HIG 285..287 HIG GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 active site 103 L 99 L 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 active site 241 R 237 R 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 active site 265 D 261 D 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 active site 270 E 266 E 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 active site 289 H 285 H 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding (2r)-2,3-dihydroxypropanoic acid 55 L - 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding (2r)-2,3-dihydroxypropanoic acid 78 S 74 S 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding (2r)-2,3-dihydroxypropanoic acid 79 V 75 V 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding (2r)-2,3-dihydroxypropanoic acid 80 G 76 G 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding (2r)-2,3-dihydroxypropanoic acid 241 R 237 R 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding (2r)-2,3-dihydroxypropanoic acid 289 H 285 H 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 79 V 75 V 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 107 T 103 T 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 156 G 152 G 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 158 G 154 G 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 160 I 156 I 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 180 G 176 S 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 181 R 177 H 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 184 R 180 K 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 212 C 208 L 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 213 S 209 P 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 218 T 214 T 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 239 I 235 I 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 241 R 237 R 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 265 D 261 D 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 289 H 285 H 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 2gcg:A 42.4 38 312 40 316 Ternary crystal structure of human glyoxylate reductase/hydroxypyruvate reductase 2e-50 197 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 291 G 287 G 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GRHPR_HUMAN 42.4 38 312 44 320 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human) 3e-50 197 binding 83..84 VG 75..76 VG 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GRHPR_HUMAN 42.4 38 312 44 320 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human) 3e-50 197 binding 162..164 GRI 154..156 GRI 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GRHPR_HUMAN 42.4 38 312 44 320 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human) 3e-50 197 binding 185..188 RQPR 177..180 HSPK 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GRHPR_HUMAN 42.4 38 312 44 320 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human) 3e-50 197 binding 217 S 209 P 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GRHPR_HUMAN 42.4 38 312 44 320 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human) 3e-50 197 binding 243 I 235 I 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GRHPR_HUMAN 42.4 38 312 44 320 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human) 3e-50 197 binding 245 R 237 R 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GRHPR_HUMAN 42.4 38 312 44 320 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human) 3e-50 197 binding 269 D 261 D 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GRHPR_HUMAN 42.4 38 312 44 320 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human) 3e-50 197 binding 293..296 HIGS 285..288 HIGS 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt GRHPR_HUMAN 42.4 38 312 44 320 Glyoxylate reductase/hydroxypyruvate reductase; EC 1.1.1.79; EC 1.1.1.81 from Homo sapiens (Human) 3e-50 197 binding 295 G 287 G 16756993 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt HPPR_PLESU 42.6 57 312 58 306 Hydroxyphenylpyruvate reductase; HPPR; EC 1.1.1.237 from Plectranthus scutellarioides (Coleus) (Solenostemon scutellarioides) 1e-47 189 binding 152..155 LGRI 153..156 MGRI 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt HPPR_PLESU 42.6 57 312 58 306 Hydroxyphenylpyruvate reductase; HPPR; EC 1.1.1.237 from Plectranthus scutellarioides (Coleus) (Solenostemon scutellarioides) 1e-47 189 binding 174..176 SRS 176..178 SHS 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt HPPR_PLESU 42.6 57 312 58 306 Hydroxyphenylpyruvate reductase; HPPR; EC 1.1.1.237 from Plectranthus scutellarioides (Coleus) (Solenostemon scutellarioides) 1e-47 189 binding 230 I 235 I 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt HPPR_PLESU 42.6 57 312 58 306 Hydroxyphenylpyruvate reductase; HPPR; EC 1.1.1.237 from Plectranthus scutellarioides (Coleus) (Solenostemon scutellarioides) 1e-47 189 binding 256 D 261 D 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 active site 98 L 99 L 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 active site 230 R 237 R 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 active site 251 A 258 A 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 active site 254 D 261 D 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 active site 259 E 266 E 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 active site 277 H 285 H 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 74 V 75 V 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 149 G 152 G 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 150 L 153 M 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 151 G 154 G 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 152 R 155 R 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 153 I 156 I 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 172 S 176 S 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 173 R 177 H 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 174 S 178 S 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 201 C 208 L 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 202 P 209 P 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 207 T 214 T 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 228 I 235 I 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 229 G 236 S 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 230 R 237 R 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 254 D 261 D 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 277 H 285 H 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3baz:A 42.6 57 312 56 304 Structure of hydroxyphenylpyruvate reductase from coleus blumei in complex with NADP+ 1e-47 188 binding nadp nicotinamide-adenine-dinucleotide phosphate 279 G 287 G 20445235 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3ddn:B 38.6 5 319 5 312 Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis 2e-46 184 active site 97 N 99 L 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3ddn:B 38.6 5 319 5 312 Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis 2e-46 184 active site 231 R 237 R 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3ddn:B 38.6 5 319 5 312 Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis 2e-46 184 active site 255 D 261 D 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3ddn:B 38.6 5 319 5 312 Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis 2e-46 184 active site 260 E 266 E 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3ddn:B 38.6 5 319 5 312 Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis 2e-46 184 active site 278 H 285 H 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3ddn:B 38.6 5 319 5 312 Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis 2e-46 184 binding 2-oxo-3-(phosphonooxy)propanoic acid 70 R 72 S 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3ddn:B 38.6 5 319 5 312 Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis 2e-46 184 binding 2-oxo-3-(phosphonooxy)propanoic acid 73 V 75 V 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3ddn:B 38.6 5 319 5 312 Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis 2e-46 184 binding 2-oxo-3-(phosphonooxy)propanoic acid 97 N 99 L 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3ddn:B 38.6 5 319 5 312 Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis 2e-46 184 binding 2-oxo-3-(phosphonooxy)propanoic acid 281 A 288 S 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3ddn:B 38.6 5 319 5 312 Crystal structure of hydroxypyruvic acid phosphate bound d-3- phosphoglycerate dehydrogenase in mycobacterium tuberculosis 2e-46 184 binding 2-oxo-3-(phosphonooxy)propanoic acid 287 Q 294 R 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 active site 96 N 99 L 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 active site 230 R 237 R 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 active site 254 D 261 D 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 active site 259 E 266 E 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 active site 277 H 285 H 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 binding serine 458 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 binding serine 460 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 binding serine 461 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 binding serine 462 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 binding serine 463 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 binding serine 464 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 binding serine 465 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 3dc2:A 38.6 5 319 4 311 Crystal structure of serine bound d-3-phosphoglycerate dehydrogenase from mycobacterium tuberculosis 2e-46 184 binding serine 484 18627175 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 active site 100 L 99 L 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 active site 237 R 237 R 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 active site 261 D 261 D 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 active site 266 E 266 E 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 active site 292 H 285 H 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 76 K 75 V 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 100 L 99 L 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 104 T 103 T 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 154 G 154 G 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 155 A 155 R 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 156 I 156 I 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 175 A 176 S 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 176 R 177 H 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 208 L 208 L 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 209 P 209 P 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 214 T 214 T 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 235 P 235 I 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 236 C 236 S 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 237 R 237 R 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5p:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase a176r variant in complex with nad 1e-43 175 binding nicotinamide-adenine-dinucleotide 292 H 285 H 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 active site 100 L 99 L 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 active site 237 R 237 R 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 active site 261 D 261 D 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 active site 266 E 266 E 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 active site 292 H 285 H 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 76 K 75 V 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 100 L 99 L 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 104 T 103 T 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 154 G 154 G 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 155 A 155 R 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 156 I 156 I 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 176 R 177 H 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 208 L 208 L 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 209 P 209 P 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 214 T 214 T 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 235 P 235 I 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 236 C 236 S 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 237 R 237 R 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 292 H 285 H 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5m:A 36.1 10 319 17 326 Thermostable phosphite dehydrogenase e175a/a176r in complex with NADP 2e-43 174 binding nadp nicotinamide-adenine-dinucleotide phosphate 294 G 287 G 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 active site 100 L 99 L 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 active site 237 R 237 R 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 active site 261 D 261 D 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 active site 266 E 266 E 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 active site 292 H 285 H 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 76 K 75 V 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 77 G 76 G 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 100 L 99 L 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 104 T 103 T 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 152 G 152 G 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 154 G 154 G 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 155 A 155 R 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 156 I 156 I 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 174 H 175 H 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 175 E - 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 176 A 176 S 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 207 A 207 T 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 208 L 208 L 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 209 P 209 P 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 235 P 235 I 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 236 C 236 S 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 237 R 237 R 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 261 D 261 D 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 292 H 285 H 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding nicotinamide-adenine-dinucleotide 294 G 287 G 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding sulfite ion 53 M 52 A 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding sulfite ion 75 L 74 S 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding sulfite ion 76 K 75 V 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding sulfite ion 77 G 76 G 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding sulfite ion 100 L 99 L 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding sulfite ion 237 R 237 R 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 4e5k:A 35.7 10 319 17 326 Thermostable phosphite dehydrogenase in complex with NAD and sulfite 8e-43 172 binding sulfite ion 292 H 285 H 22564171 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 active site 94 L 99 L 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 active site 228 R 237 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 active site 252 D 261 D 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 active site 257 E 266 E 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 active site 275 H 285 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 binding [(2r,3r,4r,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2r,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 70 V 75 V 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 binding [(2r,3r,4r,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2r,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 148 L 153 M 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 binding [(2r,3r,4r,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2r,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 149 G 154 G 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 binding [(2r,3r,4r,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2r,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 150 R 155 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 binding [(2r,3r,4r,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2r,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 151 I 156 I 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 binding [(2r,3r,4r,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2r,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 170 T 176 S 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 binding [(2r,3r,4r,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2r,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 171 R 177 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 binding [(2r,3r,4r,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2r,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 200 P 209 P 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 binding [(2r,3r,4r,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2r,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 204 S 213 E 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 binding [(2r,3r,4r,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2r,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 205 T 214 T 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5j23:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with 2'-phospho-adp-ribose 8e-43 172 binding [(2r,3r,4r,5r)-5-(6-amino-9h-purin-9-yl)-3-hydroxy-4-(phosphonooxy)tetrahydrofuran-2-yl]methyl [(2r,3s,4r,5r)-3,4,5-trihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate 228 R 237 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 active site 95 L 99 L 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 active site 229 R 237 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 active site 253 D 261 D 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 active site 258 E 266 E 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 active site 276 H 285 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding 2-keto-D-gluconic acid 70 G 74 S 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding 2-keto-D-gluconic acid 71 V 75 V 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding 2-keto-D-gluconic acid 72 G 76 G 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding 2-keto-D-gluconic acid 229 R 237 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding 2-keto-D-gluconic acid 276 H 285 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding 2-keto-D-gluconic acid 279 S 288 S 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding 2-keto-D-gluconic acid 285 R 294 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 71 V 75 V 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 99 V 103 T 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 149 L 153 M 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 150 G 154 G 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 151 R 155 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 152 I 156 I 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 171 T 176 S 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 172 R 177 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 200 V 208 L 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 201 P 209 P 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 205 S 213 E 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 206 T 214 T 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 227 V 235 I 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 228 G 236 S 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 229 R 237 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 276 H 285 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7n:A 36.7 2 305 2 296 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and 2-keto-d-gluconic acid 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 278 A 287 G 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 active site 96 L 99 L 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 active site 230 R 237 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 active site 254 D 261 D 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 active site 259 E 266 E 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 active site 277 H 285 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 72 V 75 V 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 100 V 103 T 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 148 F 151 I 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 150 L 153 M 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 151 G 154 G 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 152 R 155 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 153 I 156 I 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 172 T 176 S 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 173 R 177 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 201 V 208 L 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 202 P 209 P 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 206 S 213 E 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 207 T 214 T 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 228 V 235 I 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 229 G 236 S 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 230 R 237 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 277 H 285 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v6q:B 36.7 2 305 3 297 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADP and malonate 9e-43 172 binding nadp nicotinamide-adenine-dinucleotide phosphate 279 A 287 G 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 active site 94 L 99 L 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 active site 228 R 237 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 active site 252 D 261 D 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 active site 257 E 266 E 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 active site 275 H 285 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 70 V 75 V 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 98 V 103 T 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 146 F 151 I 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 148 L 153 M 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 149 G 154 G 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 150 R 155 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 151 I 156 I 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 170 T 176 S 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 171 R 177 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 199 V 208 L 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 200 P 209 P 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 204 S 213 E 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 205 T 214 T 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 226 V 235 I 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 227 G 236 S 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 228 R 237 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 275 H 285 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate 277 A 287 G 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding oxalate ion 69 G 74 S 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding oxalate ion 70 V 75 V 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding oxalate ion 71 G 76 G 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding oxalate ion 228 R 237 R 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 5v7g:A 36.7 2 305 1 295 Crystal structure of NADPH-dependent glyoxylate/hydroxypyruvate reductase smc04462 (smghrb) from sinorhizobium meliloti in complex with NADPH and oxalate 1e-42 172 binding oxalate ion 275 H 285 H 29309127 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 104 T 103 T GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 151 R 151 I GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 154 G 154 G GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 155 A 155 R GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 156 V 156 I GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 175 D 176 S GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 207 A 207 T GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 208 V 208 L GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 209 P 209 P GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 214 T 214 T GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 235 A 235 I GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 236 C 236 S GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6ih6:A 36.3 56 319 57 327 Phosphite dehydrogenase mutant i151r/p176r/m207a from ralstonia sp. 4506 in complex with non-natural cofactor nicotinamide cytosine dinucleotide 6e-37 153 binding [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate 237 R 237 R GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 binding 78 T 75 V GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 to W: in PHGDHD; results in a 2-fold decrease... 135 R 132 K 19235232 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 binding 155..156 RI 155..156 RI GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 binding 175 D 176 S GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 binding 207 T 208 L GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 binding 234..236 CAR 235..237 ISR GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 binding 260 D 261 D GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 to M: in PHGDHD; results in a four-fold decrease... 261 V 262 V 19235232 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 binding 283..286 HLGA 285..288 HIGS GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 modified: Initiator methionine, Removed 1 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 modified: N-acetylalanine 2 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 A → T: in PHGDHD; results in almost undetectable... 373 19235232 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 G → S: in PHGDHD; results in a 2-fold... 377 19235232 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 V → M: in PHGDHD; results in almost undetectable... 425 11055895,19235232 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B SwissProt SERA_HUMAN 32.3 36 322 42 320 D-3-phosphoglycerate dehydrogenase; 3-PGDH; 2-oxoglutarate reductase; Malate dehydrogenase; EC 1.1.1.95; EC 1.1.1.399; EC 1.1.1.37 from Homo sapiens (Human) 4e-36 150 V → M: in PHGDHD; results in almost undetectable... 490 11055895,11751922,19235232 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6plg:A 32.6 36 307 37 297 Crystal structure of human phgdh complexed with compound 15 2e-35 147 binding (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid 149 G 154 G 31327531 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6plg:A 32.6 36 307 37 297 Crystal structure of human phgdh complexed with compound 15 2e-35 147 binding (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid 150 R 155 R 31327531 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6plg:A 32.6 36 307 37 297 Crystal structure of human phgdh complexed with compound 15 2e-35 147 binding (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid 170 D 176 S 31327531 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6plg:A 32.6 36 307 37 297 Crystal structure of human phgdh complexed with compound 15 2e-35 147 binding (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid 171 P 177 H 31327531 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6plg:A 32.6 36 307 37 297 Crystal structure of human phgdh complexed with compound 15 2e-35 147 binding (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid 172 I 178 S 31327531 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6plg:A 32.6 36 307 37 297 Crystal structure of human phgdh complexed with compound 15 2e-35 147 binding (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid 173 I 179 P 31327531 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6plg:A 32.6 36 307 37 297 Crystal structure of human phgdh complexed with compound 15 2e-35 147 binding (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid 201 H 207 T 31327531 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6plg:A 32.6 36 307 37 297 Crystal structure of human phgdh complexed with compound 15 2e-35 147 binding (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid 202 T 208 L 31327531 GFF2462 PS417_12555 bifunctional glyoxylate/hydroxypyruvate reductase B PDB 6plg:A 32.6 36 307 37 297 Crystal structure of human phgdh complexed with compound 15 2e-35 147 binding (2S)-(4-{3-[(4,5-dichloro-1-methyl-1H-indole-2-carbonyl)amino]oxetan-3-yl}phenyl)(pyridin-3-yl)acetic acid 205 L 211 T 31327531