queryId subjectDb subjectId identity queryAlnBegin queryAlnEnd sujectAlnBegin subjectAlnEnd subjectDescription evalue bits subjectSite subjectSiteRange subjectSiteSeq querySiteRange querySiteSeq pubMedIds HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt LEUC_SCHPO 64.9 3 466 9 478 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 1e-178 624 modified: Phosphoserine 486 18257517 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt LEUC_SCHPO 64.9 3 466 9 478 3-isopropylmalate dehydratase; Alpha-IPM isomerase; IPMI; Isopropylmalate isomerase; EC 4.2.1.33 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 1e-178 624 modified: Phosphoserine 488 18257517 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4kp1:A 34.8 27 466 28 423 Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) 2e-59 228 active site 64 D 62 D 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4kp1:A 34.8 27 466 28 423 Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) 2e-59 228 active site 65 H 63 H 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4kp1:A 34.8 27 466 28 423 Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) 2e-59 228 active site 121 D 128 D 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4kp1:A 34.8 27 466 28 423 Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) 2e-59 228 active site 387 R 431 R 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4kp1:A 34.8 27 466 28 423 Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) 2e-59 228 binding 2,4-dimethylpentane-2,4-diol 299 F 343 F 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4kp1:A 34.8 27 466 28 423 Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) 2e-59 228 binding 2,4-dimethylpentane-2,4-diol 302 S 346 S 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4kp1:A 34.8 27 466 28 423 Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) 2e-59 228 binding 2,4-dimethylpentane-2,4-diol 383 S 427 S 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4kp1:A 34.8 27 466 28 423 Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) 2e-59 228 binding 2,4-dimethylpentane-2,4-diol 389 F 433 F 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4kp1:A 34.8 27 466 28 423 Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) 2e-59 228 binding magnesium ion 303 C 347 C 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4kp1:A 34.8 27 466 28 423 Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) 2e-59 228 binding magnesium ion 304 T 348 T 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4kp1:A 34.8 27 466 28 423 Crystal structure of ipm isomerase large subunit from methanococcus jannaschii (mj0499) 2e-59 228 binding magnesium ion 387 R 431 R 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4nqy:A 33.2 27 464 27 408 The reduced form of mj0499 5e-56 217 active site 63 D 62 D 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4nqy:A 33.2 27 464 27 408 The reduced form of mj0499 5e-56 217 active site 108 D 128 D 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4nqy:A 33.2 27 464 27 408 The reduced form of mj0499 5e-56 217 active site 374 R 431 R 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4nqy:A 33.2 27 464 27 408 The reduced form of mj0499 5e-56 217 binding zinc ion 351 C 408 C 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 4nqy:A 33.2 27 464 27 408 The reduced form of mj0499 5e-56 217 binding zinc ion 354 C 411 C 24699638 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_YEAST 28.7 106 458 167 500 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 6e-31 133 modified: transit peptide, Mitochondrion 1..16 15975908 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_YEAST 28.7 106 458 167 500 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 6e-31 133 R→K: Strongly diminishes the catalytic activity towards both known... 604 23106124 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON2_YEAST 26.2 86 458 151 505 Homocitrate dehydratase, mitochondrial; Aconitase 2; EC 4.2.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 2e-29 129 K→R: Reduces catalytic activity towards homoaconitate by 45% and... 610 23106124 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 active site 165 D 128 D 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 active site 447 R 431 R 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 binding fe3-s4 cluster 145 I 107 I 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 binding fe3-s4 cluster 147 H 109 H 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 binding fe3-s4 cluster 167 H 130 H 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 binding fe3-s4 cluster 358 C 347 C 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 binding fe3-s4 cluster 421 C 408 C 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 binding fe3-s4 cluster 424 C 411 C 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 binding fe3-s4 cluster 446 N 430 N 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 binding tricarballylic acid 198 K 161 R 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 binding tricarballylic acid 235 G 198 G 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 active site 100 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 active site 101 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 active site 642 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 active site 644 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 5acn:A 29.2 106 458 144 476 Structure of activated aconitase. Formation of the (4fe-4s) cluster in the crystal 9e-29 126 binding tricarballylic acid 666 2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 active site 164 D 128 D 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 active site 446 R 431 R 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding citrate anion 164 D 128 D 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding citrate anion 165 S 129 S 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding citrate anion 446 R 431 R 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding citrate anion 451 R 436 R 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding oxygen atom 164 D 128 D 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding oxygen atom 166 H 130 H 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding iron/sulfur cluster 164 D 128 D 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding iron/sulfur cluster 166 H 130 H 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding iron/sulfur cluster 356 S 346 S 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding iron/sulfur cluster 357 C 347 C 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding iron/sulfur cluster 420 C 408 C 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding iron/sulfur cluster 423 C 411 C 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 active site 99 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 active site 100 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 active site 641 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 active site 643 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding citrate anion 71 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding citrate anion 100 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding citrate anion 579 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding citrate anion 641 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding citrate anion 642 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding citrate anion 643 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1b0k:A 29.2 106 458 143 475 S642a:fluorocitrate complex of aconitase 1e-28 126 binding iron/sulfur cluster 100 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_PIG 29.2 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig) 1e-28 126 binding 192..194 DSH 128..130 DSH 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_PIG 29.2 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig) 1e-28 126 binding 385 C 347 C 10631981,2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_PIG 29.2 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig) 1e-28 126 binding 448 C 408 C 10631981,2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_PIG 29.2 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig) 1e-28 126 binding 451 C 411 C 10631981,2726740 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_PIG 29.2 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig) 1e-28 126 binding 474 R 431 R 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_PIG 29.2 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig) 1e-28 126 binding 479 R 436 R 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_PIG 29.2 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig) 1e-28 126 modified: Pyrrolidone carboxylic acid 28 2303429 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_PIG 29.2 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig) 1e-28 126 binding 99 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_PIG 29.2 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig) 1e-28 126 binding 607 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_PIG 29.2 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig) 1e-28 126 binding 670..671 10631981 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 active site 164 D 128 D 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 active site 446 R 431 R 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding 2-hydroxy-2-nitromethyl succinic acid 164 D 128 D 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding 2-hydroxy-2-nitromethyl succinic acid 165 S 129 S 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding 2-hydroxy-2-nitromethyl succinic acid 446 R 431 R 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding 2-hydroxy-2-nitromethyl succinic acid 451 R 436 R 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding iron/sulfur cluster 144 I 107 I 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding iron/sulfur cluster 166 H 130 H 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding iron/sulfur cluster 356 S 346 S 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding iron/sulfur cluster 357 C 347 C 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding iron/sulfur cluster 420 C 408 C 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding iron/sulfur cluster 423 C 411 C 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 active site 99 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 active site 100 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 active site 641 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 active site 643 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding 2-hydroxy-2-nitromethyl succinic acid 71 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding 2-hydroxy-2-nitromethyl succinic acid 100 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding 2-hydroxy-2-nitromethyl succinic acid 579 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding 2-hydroxy-2-nitromethyl succinic acid 641 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding 2-hydroxy-2-nitromethyl succinic acid 642 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1nis:A 28.7 106 458 143 475 Crystal structure of aconitase with trans-aconitate and nitrocitrate bound 2e-27 122 binding iron/sulfur cluster 100 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 active site 164 D 128 D 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 active site 446 R 431 R 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding nitroisocitric acid 164 D 128 D 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding nitroisocitric acid 165 S 129 S 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding nitroisocitric acid 446 R 431 R 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding nitroisocitric acid 451 R 436 R 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding iron/sulfur cluster 164 D 128 D 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding iron/sulfur cluster 166 H 130 H 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding iron/sulfur cluster 356 S 346 S 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding iron/sulfur cluster 357 C 347 C 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding iron/sulfur cluster 420 C 408 C 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding iron/sulfur cluster 423 C 411 C 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding iron/sulfur cluster 424 I 412 L 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 active site 99 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 active site 100 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 active site 641 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 active site 643 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding nitroisocitric acid 71 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding nitroisocitric acid 74 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding nitroisocitric acid 100 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding nitroisocitric acid 579 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding nitroisocitric acid 641 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding nitroisocitric acid 642 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding nitroisocitric acid 643 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 8acn:A 28.7 106 458 143 475 Crystal structures of aconitase with isocitrate and nitroisocitrate bound 2e-27 122 binding iron/sulfur cluster 100 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 active site 164 D 128 D 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 active site 446 R 431 R 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding 4-hydroxy-aconitate ion 164 D 128 D 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding 4-hydroxy-aconitate ion 165 S 129 S 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding 4-hydroxy-aconitate ion 446 R 431 R 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding 4-hydroxy-aconitate ion 451 R 436 R 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding iron/sulfur cluster 164 D 128 D 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding iron/sulfur cluster 166 H 130 H 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding iron/sulfur cluster 356 S 346 S 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding iron/sulfur cluster 357 C 347 C 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding iron/sulfur cluster 420 C 408 C 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding iron/sulfur cluster 423 C 411 C 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding iron/sulfur cluster 424 I 412 L 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding iron/sulfur cluster 451 R 436 R 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 active site 99 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 active site 100 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 active site 641 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 active site 643 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding 4-hydroxy-aconitate ion 71 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding 4-hydroxy-aconitate ion 74 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding 4-hydroxy-aconitate ion 100 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding 4-hydroxy-aconitate ion 579 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding 4-hydroxy-aconitate ion 641 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding 4-hydroxy-aconitate ion 642 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding 4-hydroxy-aconitate ion 643 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1fgh:A 28.7 106 458 143 475 Complex with 4-hydroxy-trans-aconitate 2e-27 122 binding iron/sulfur cluster 100 8942997 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 164 D 128 D 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 446 R 431 R 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 144 I 107 I 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 166 H 130 H 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 357 C 347 C 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 420 C 408 C 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 423 C 411 C 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 99 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 100 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 641 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 643 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding sulfate ion 71 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding sulfate ion 579 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1amj:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding sulfate ion 643 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 164 D 128 D 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 446 R 431 R 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding alpha-methylisocitric acid 164 D 128 D 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding alpha-methylisocitric acid 165 S 129 S 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding alpha-methylisocitric acid 446 R 431 R 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding alpha-methylisocitric acid 451 R 436 R 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 144 I 107 I 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 164 D 128 D 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 166 H 130 H 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 356 S 346 S 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 357 C 347 C 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 420 C 408 C 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 423 C 411 C 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 445 N 430 N 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 99 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 100 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 641 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 active site 643 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding alpha-methylisocitric acid 71 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding alpha-methylisocitric acid 74 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding alpha-methylisocitric acid 100 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding alpha-methylisocitric acid 579 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding alpha-methylisocitric acid 641 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding alpha-methylisocitric acid 642 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding alpha-methylisocitric acid 643 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1ami:A 28.7 106 458 143 475 Steric and conformational features of the aconitase mechanism 2e-27 122 binding iron/sulfur cluster 100 7675781 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 active site 164 D 128 D 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 active site 446 R 431 R 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding iron/sulfur cluster 144 I 107 I 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding iron/sulfur cluster 164 D 128 D 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding iron/sulfur cluster 166 H 130 H 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding iron/sulfur cluster 356 S 346 S 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding iron/sulfur cluster 357 C 347 C 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding iron/sulfur cluster 420 C 408 C 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding iron/sulfur cluster 423 C 411 C 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding iron/sulfur cluster 445 N 430 N 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding aconitate ion 164 D 128 D 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding aconitate ion 165 S 129 S 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding aconitate ion 446 R 431 R 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding aconitate ion 451 R 436 R 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 active site 99 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 active site 100 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 active site 641 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 active site 643 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding iron/sulfur cluster 100 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding aconitate ion 71 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding aconitate ion 579 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding aconitate ion 641 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding aconitate ion 642 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 1aco:A 28.7 106 458 143 475 Crystal structure of aconitase with transaconitate bound 2e-27 122 binding aconitate ion 643 8151704 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_BOVIN 28.7 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine) 5e-27 120 binding 192..194 DSH 128..130 DSH 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_BOVIN 28.7 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine) 5e-27 120 binding 385 C 347 C 1547214,3372519 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_BOVIN 28.7 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine) 5e-27 120 binding 448 C 408 C 1547214,3372519 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_BOVIN 28.7 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine) 5e-27 120 binding 451 C 411 C 1547214,3372519 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_BOVIN 28.7 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine) 5e-27 120 binding 474 R 431 R 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_BOVIN 28.7 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine) 5e-27 120 binding 479 R 436 R 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_BOVIN 28.7 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine) 5e-27 120 binding 99 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_BOVIN 28.7 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine) 5e-27 120 binding 607 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACON_BOVIN 28.7 106 458 171 503 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine) 5e-27 120 binding 670..671 1547214 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACNA_BACSU 27.8 107 458 198 577 Aconitate hydratase A; ACN; Aconitase; Aconitate/2-methylaconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.- from Bacillus subtilis (strain 168) 4e-18 91.3 mutation to S: Loss of aconitase activity. It is... 450 C 347 C 23354745 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACNA_BACSU 27.8 107 458 198 577 Aconitate hydratase A; ACN; Aconitase; Aconitate/2-methylaconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.- from Bacillus subtilis (strain 168) 4e-18 91.3 modified: Initiator methionine, Removed 1 3110133 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACNA_BACSU 27.8 107 458 198 577 Aconitate hydratase A; ACN; Aconitase; Aconitate/2-methylaconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.- from Bacillus subtilis (strain 168) 4e-18 91.3 R→E: Same aconitase activity compared to the wild-type. It... 741 23354745 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACO3M_ARATH 25.6 106 458 271 660 Aconitate hydratase 3, mitochondrial; Aconitase 3; mACO1; Citrate hydro-lyase 3; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) 8e-17 87.0 modified: Phosphoserine 91 25307043 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACOHC_HUMAN 26.1 106 458 175 564 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human) 1e-16 86.7 mutation to S: No effect on aconitase activity or... 300 C 223 A 8041788 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACOHC_HUMAN 26.1 106 458 175 564 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human) 1e-16 86.7 to M: in dbSNP:rs150373174 318 T 241 E 23033978 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACOHC_HUMAN 26.1 106 458 175 564 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human) 1e-16 86.7 mutation to S: Loss of aconitase activity. Leads to... 437 C 347 C 8041788 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACOHC_HUMAN 26.1 106 458 175 564 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human) 1e-16 86.7 mutation to S: Loss of aconitase activity. Leads to... 503 C 408 C 8041788 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACOHC_HUMAN 26.1 106 458 175 564 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human) 1e-16 86.7 mutation to S: Loss of aconitase activity. Leads to... 506 C 411 C 8041788 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACOHC_HUMAN 26.1 106 458 175 564 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human) 1e-16 86.7 mutation to Q: Strongly reduced RNA binding. 536 R 431 R 8041788 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACOHC_HUMAN 26.1 106 458 175 564 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human) 1e-16 86.7 mutation to Q: Strongly reduced RNA binding. 541 R 436 R 8041788 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACOHC_HUMAN 26.1 106 458 175 564 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human) 1e-16 86.7 R→K: No effect on RNA binding. 699 8041788 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACOHC_HUMAN 26.1 106 458 175 564 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human) 1e-16 86.7 S→A: No effect on iron-regulated RNA binding. Loss of... 778 8041788 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase SwissProt ACOHC_HUMAN 26.1 106 458 175 564 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human) 1e-16 86.7 R→Q: Nearly abolishes RNA binding. 780 8041788 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 active site 204 D 128 D 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 active site 535 R 431 R 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 binding iron/sulfur cluster 175 I 107 I 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 binding iron/sulfur cluster 206 H 130 H 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 binding iron/sulfur cluster 436 C 347 C 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 binding iron/sulfur cluster 502 C 408 C 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 binding iron/sulfur cluster 505 C 411 C 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 binding iron/sulfur cluster 506 I 412 L 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 binding iron/sulfur cluster 534 N 430 N 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 active site 124 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 active site 125 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 active site 777 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 2b3x:A 26.1 106 458 174 563 Structure of an orthorhombic crystal form of human cytosolic aconitase (irp1) 1e-16 86.3 active site 779 16407072 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 active site 186 D 128 D 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 active site 505 R 431 R 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 188 H 130 H 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 243 L 185 L 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 250 R 192 G 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 279 N 221 N 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 283 E 225 E 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 352 S 289 T 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 357 P 294 P 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 360 K 297 V 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 419 T 348 T 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 420 N 349 N 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 421 T 350 S 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 504 N 430 N 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 505 R 431 R 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 520 L 445 L 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 active site 124 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 active site 125 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 active site 739 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 active site 741 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 125 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 126 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 642 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 643 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 644 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 645 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 646 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 649 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 665 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 669 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 671 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 674 17185597 HSERO_RS16515 HSERO_RS16515 isopropylmalate isomerase PDB 3snp:A 26.5 106 458 156 533 Crystal structure analysis of iron regulatory protein 1 in complex with ferritin h ire RNA 4e-11 68.2 binding rna 741 17185597