queryId subjectDb subjectId identity queryAlnBegin queryAlnEnd sujectAlnBegin subjectAlnEnd subjectDescription evalue bits subjectSite subjectSiteRange subjectSiteSeq querySiteRange querySiteSeq pubMedIds HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 active site 93 C 90 C 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 active site 359 A 356 H 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 active site 389 C 386 C 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 active site 391 G 388 G 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding coenzyme a 93 C 90 C 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding coenzyme a 148 I 145 I 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding coenzyme a 229 R 227 R 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding coenzyme a 232 T 229 T 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding coenzyme a 252 A 249 A 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding coenzyme a 256 S 253 S 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding coenzyme a 325 N 322 N 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding coenzyme a 328 F 325 F 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding hexanal 61 N 58 N 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding hexanal 146 T 143 T 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding hexanal 148 I 145 I 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding hexanal 149 G 146 G 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding hexanal 151 R 148 R 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcc:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a 1e-158 556 binding hexanal 361 L 358 L 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 active site 93 C 90 C 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 active site 359 A 356 H 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 active site 389 C 386 C 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 active site 391 G 388 G 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 binding coenzyme a 93 C 90 C 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 binding coenzyme a 148 I 145 I 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 binding coenzyme a 229 R 227 R 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 binding coenzyme a 252 A 249 A 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 binding coenzyme a 256 S 253 S 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 binding coenzyme a 257 G 254 G 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 binding coenzyme a 325 N 322 N 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcb:A 71.8 1 400 4 403 Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa 1e-158 556 binding coenzyme a 328 F 325 F 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 active site 94 S 90 C 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 active site 357 A 356 H 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 active site 387 C 386 C 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 active site 389 G 388 G 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding coenzyme a 149 I 145 I 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding coenzyme a 167 M 163 M 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding coenzyme a 227 R 227 R 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding coenzyme a 230 T 229 T 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding coenzyme a 250 A 249 A 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding coenzyme a 254 S 253 S 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding coenzyme a 255 G 254 G 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding coenzyme a 325 A 324 A 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding coenzyme a 357 A 356 H 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding octanal 62 N 58 N 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding octanal 147 T 143 T 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding octanal 148 T 144 T 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding octanal 149 I 145 I 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding octanal 150 G 146 G 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding octanal 152 R 148 R 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 6pcd:A 70.8 1 400 5 401 Crystal structure of beta-ketoadipyl-coa thiolase mutant (c90s-h356a) in complex octanoyl coenzyme a 1e-155 546 binding octanal 359 L 358 L 32647822 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THLA_CLOAB 44.4 1 399 1 391 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; CaTHL; EC 2.3.1.9 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 6e-85 312 mutation to Q: 3-fold increase in thiolase activity, prevents... 77 V 79 Q 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THLA_CLOAB 44.4 1 399 1 391 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; CaTHL; EC 2.3.1.9 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 6e-85 312 modified: Disulfide link with 378, In inhibited form 88 C 90 C 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THLA_CLOAB 44.4 1 399 1 391 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; CaTHL; EC 2.3.1.9 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 6e-85 312 binding 96 S 98 G 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THLA_CLOAB 44.4 1 399 1 391 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; CaTHL; EC 2.3.1.9 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 6e-85 312 mutation to Y: 3-fold increase in thiolase activity, prevents... 153 N 154 M 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THLA_CLOAB 44.4 1 399 1 391 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; CaTHL; EC 2.3.1.9 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 6e-85 312 binding 279..280 GS 285..286 AT 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THLA_CLOAB 44.4 1 399 1 391 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; CaTHL; EC 2.3.1.9 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 6e-85 312 mutation to K: 3-fold increase in thiolase activity, prevents... 286 A 292 R 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THLA_CLOAB 44.4 1 399 1 391 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; CaTHL; EC 2.3.1.9 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 6e-85 312 modified: Disulfide link with 88, In inhibited form 378 C 386 C 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THLA_CLOAB 44.4 1 399 1 391 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; CaTHL; EC 2.3.1.9 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) 6e-85 312 binding 386 A 394 A 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 active site 88 C 90 C 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 active site 348 H 356 H 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 active site 378 S 386 C 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 active site 380 G 388 G 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 binding coenzyme a 148 L 149 F 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 binding coenzyme a 156 H 157 K 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 binding coenzyme a 220 R 227 R 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 binding coenzyme a 231 L 237 L 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 binding coenzyme a 243 A 249 A 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 binding coenzyme a 247 S 253 S 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 binding coenzyme a 319 F 325 F 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4xl4:A 44.1 1 399 1 391 Crystal structure of thiolase from clostridium acetobutylicum in complex with coa 8e-84 309 binding coenzyme a 348 H 356 H 26391388 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 active site 87 C 90 C 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 active site 354 H 356 H 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 active site 384 C 386 C 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 active site 386 G 388 G 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 87 C 90 C 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 146 R - 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 160 M 163 M 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 220 R 227 R 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 246 A 249 A 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 247 G 250 G 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 250 S 253 S 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 252 Q 255 V 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 291 M 294 M 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 321 A 324 A 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 322 F 325 F 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5bz4:K 42.8 2 400 1 398 Crystal structure of a t1-like thiolase (coa-complex) from mycobacterium smegmatis 1e-80 298 binding coenzyme a 354 H 356 H 26627655 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIL_CUPNH 44.1 1 399 1 392 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) 2e-79 294 active site, Acyl-thioester intermediate; mutation to S: Almost complete loss of acetoacetyl-CoA thiolase... 88 C 90 C 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIL_CUPNH 44.1 1 399 1 392 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) 2e-79 294 mutation to A: Almost complete loss of acetoacetyl-CoA thiolase... 156 H 162 A 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIL_CUPNH 44.1 1 399 1 392 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) 2e-79 294 mutation to A: About 50% loss of acetoacetyl-CoA thiolase...; mutation to Y: 2-fold increase of acetoacetyl-CoA thiolase activity. 219 F 225 H 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIL_CUPNH 44.1 1 399 1 392 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) 2e-79 294 mutation to A: Almost complete loss of acetoacetyl-CoA thiolase... 221 R 227 R 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIL_CUPNH 44.1 1 399 1 392 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) 2e-79 294 mutation to A: About 40% loss of acetoacetyl-CoA thiolase... 248 S 253 S 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIL_CUPNH 44.1 1 399 1 392 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) 2e-79 294 mutation to A: Almost complete loss of acetoacetyl-CoA thiolase... 349 H 356 H 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIL_CUPNH 44.1 1 399 1 392 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) 2e-79 294 mutation to S: Almost complete loss of acetoacetyl-CoA thiolase... 379 C 386 C 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 active site 88 S 90 C 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 active site 349 H 356 H 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 active site 379 C 386 C 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 active site 381 G 388 G 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 binding coenzyme a 88 S 90 C 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 binding coenzyme a 148 L 153 L 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 binding coenzyme a 221 R 227 R 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 binding coenzyme a 236 F 241 V 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 binding coenzyme a 244 A 249 A 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 binding coenzyme a 248 S 253 S 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 binding coenzyme a 250 L 255 V 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 binding coenzyme a 319 A 324 A 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 binding coenzyme a 320 F 325 F 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4o9c:C 43.9 1 399 1 392 Crystal structure of beta-ketothiolase (phaa) from ralstonia eutropha h16 2e-78 291 binding coenzyme a 349 H 356 H 25152395 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIM_HUMAN 42.4 1 398 4 394 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; Acyl-CoA hydrolase, mitochondrial; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1; EC 2.3.1.16; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2 from Homo sapiens (Human) 5e-78 290 mutation to A: Decreased acyl-CoA hydrolase activity.; mutation to S: Decreased acyl-CoA hydrolase activity; when associated... 92 C 90 C 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIM_HUMAN 42.4 1 398 4 394 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; Acyl-CoA hydrolase, mitochondrial; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1; EC 2.3.1.16; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2 from Homo sapiens (Human) 5e-78 290 binding 224 R 227 R 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIM_HUMAN 42.4 1 398 4 394 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; Acyl-CoA hydrolase, mitochondrial; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1; EC 2.3.1.16; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2 from Homo sapiens (Human) 5e-78 290 binding 227 T 229 T 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIM_HUMAN 42.4 1 398 4 394 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; Acyl-CoA hydrolase, mitochondrial; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1; EC 2.3.1.16; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2 from Homo sapiens (Human) 5e-78 290 binding 251 S 253 S 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIM_HUMAN 42.4 1 398 4 394 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; Acyl-CoA hydrolase, mitochondrial; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1; EC 2.3.1.16; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2 from Homo sapiens (Human) 5e-78 290 mutation to S: Decreased acyl-CoA hydrolase activity; when associated... 382 C 386 C 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu1:A 42.7 4 400 4 391 Biosynthetic thiolase from z. Ramigera. Complex of with o-pantheteine- 11-pivalate. 1e-76 285 active site 88 C 90 C 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu1:A 42.7 4 400 4 391 Biosynthetic thiolase from z. Ramigera. Complex of with o-pantheteine- 11-pivalate. 1e-76 285 active site 347 H 356 H 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu1:A 42.7 4 400 4 391 Biosynthetic thiolase from z. Ramigera. Complex of with o-pantheteine- 11-pivalate. 1e-76 285 active site 377 C 386 C 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu1:A 42.7 4 400 4 391 Biosynthetic thiolase from z. Ramigera. Complex of with o-pantheteine- 11-pivalate. 1e-76 285 active site 379 G 388 G 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu1:A 42.7 4 400 4 391 Biosynthetic thiolase from z. Ramigera. Complex of with o-pantheteine- 11-pivalate. 1e-76 285 binding pantothenyl-aminoethanol-11-pivalic acid 155 H 161 D 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu1:A 42.7 4 400 4 391 Biosynthetic thiolase from z. Ramigera. Complex of with o-pantheteine- 11-pivalate. 1e-76 285 binding pantothenyl-aminoethanol-11-pivalic acid 234 F 241 V 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu1:A 42.7 4 400 4 391 Biosynthetic thiolase from z. Ramigera. Complex of with o-pantheteine- 11-pivalate. 1e-76 285 binding pantothenyl-aminoethanol-11-pivalic acid 246 S 253 S 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu1:A 42.7 4 400 4 391 Biosynthetic thiolase from z. Ramigera. Complex of with o-pantheteine- 11-pivalate. 1e-76 285 binding pantothenyl-aminoethanol-11-pivalic acid 317 A 324 A 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu1:A 42.7 4 400 4 391 Biosynthetic thiolase from z. Ramigera. Complex of with o-pantheteine- 11-pivalate. 1e-76 285 binding pantothenyl-aminoethanol-11-pivalic acid 318 F 325 F 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu1:A 42.7 4 400 4 391 Biosynthetic thiolase from z. Ramigera. Complex of with o-pantheteine- 11-pivalate. 1e-76 285 binding pantothenyl-aminoethanol-11-pivalic acid 347 H 356 H 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 active site 89 C 90 C HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 active site 348 H 356 H HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 active site 378 C 386 C HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 active site 380 G 388 G HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 binding pantothenyl-aminoethanol-acetate pivalic acid 148 L 153 L HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 binding pantothenyl-aminoethanol-acetate pivalic acid 156 H 161 D HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 binding pantothenyl-aminoethanol-acetate pivalic acid 157 M 163 M HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 binding pantothenyl-aminoethanol-acetate pivalic acid 235 F 241 V HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 binding pantothenyl-aminoethanol-acetate pivalic acid 243 A 249 A HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 binding pantothenyl-aminoethanol-acetate pivalic acid 247 S 253 S HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 binding pantothenyl-aminoethanol-acetate pivalic acid 318 A 324 A HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 binding pantothenyl-aminoethanol-acetate pivalic acid 319 F 325 F HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1ou6:A 42.7 4 400 5 392 Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate 1e-76 285 binding pantothenyl-aminoethanol-acetate pivalic acid 348 H 356 H HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu2:A 42.7 4 400 2 389 Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. 1e-76 285 active site 86 C 90 C 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu2:A 42.7 4 400 2 389 Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. 1e-76 285 active site 345 H 356 H 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu2:A 42.7 4 400 2 389 Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. 1e-76 285 active site 375 C 386 C 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu2:A 42.7 4 400 2 389 Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. 1e-76 285 active site 377 G 388 G 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu2:A 42.7 4 400 2 389 Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. 1e-76 285 binding (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl 2,2-dimethylpropanoate 153 H 161 D 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu2:A 42.7 4 400 2 389 Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. 1e-76 285 binding (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl 2,2-dimethylpropanoate 154 M 163 M 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu2:A 42.7 4 400 2 389 Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. 1e-76 285 binding (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl 2,2-dimethylpropanoate 232 F 241 V 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu2:A 42.7 4 400 2 389 Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. 1e-76 285 binding (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl 2,2-dimethylpropanoate 244 S 253 S 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu2:A 42.7 4 400 2 389 Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. 1e-76 285 binding (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl 2,2-dimethylpropanoate 245 G 254 G 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu2:A 42.7 4 400 2 389 Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. 1e-76 285 binding (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl 2,2-dimethylpropanoate 316 F 325 F 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2vu2:A 42.7 4 400 2 389 Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. 1e-76 285 binding (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl 2,2-dimethylpropanoate 345 H 356 H 19016856 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 active site 86 C 90 C 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 active site 345 H 356 H 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 active site 375 C 386 C 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 active site 377 G 388 G 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 86 C 90 C 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 145 L 153 L 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 153 H 161 D 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 154 M 163 M 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 217 R 227 R 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 224 S 233 A 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 225 M 234 L 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 240 A 249 A 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 244 S 253 S 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 285 M 294 M 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 315 A 324 A 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 316 F 325 F 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 345 H 356 H 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dm3:A 42.7 4 400 2 389 Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa 1e-76 285 binding acetyl coenzyme *a 375 C 386 C 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 active site 86 C 90 C 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 active site 345 H 356 H 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 active site 375 C 386 C 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 active site 377 G 388 G 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 binding coenzyme a 86 C 90 C 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 binding coenzyme a 145 L 153 L 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 binding coenzyme a 153 H 161 D 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 binding coenzyme a 154 M 163 M 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 binding coenzyme a 217 R 227 R 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 binding coenzyme a 228 L 237 L 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 binding coenzyme a 240 A 249 A 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 binding coenzyme a 244 S 253 S 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1dlv:A 42.7 4 400 2 389 Biosynthetic thiolase from zoogloea ramigera in complex with coa 1e-76 285 binding coenzyme a 345 H 356 H 10764581 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 active site 90 C 90 C 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 active site 348 A 353 A 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 active site 378 A 383 C 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 active site 380 L 385 M 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 binding [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] phosphono hydrogen phosphate 90 C 90 C 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 binding [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] phosphono hydrogen phosphate 151 L 153 L 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 binding [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] phosphono hydrogen phosphate 246 A 249 A 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 binding [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] phosphono hydrogen phosphate 250 S 253 S 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 binding [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] phosphono hydrogen phosphate 252 I 255 V 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 binding [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] phosphono hydrogen phosphate 321 A 324 A 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 binding [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] phosphono hydrogen phosphate 322 F 325 F 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:D 45.8 1 399 3 394 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 2e-76 285 binding [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(2-sulfanylethylamino)propyl]amino]butyl] phosphono hydrogen phosphate 351 H 356 H 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIL_SHIZO 43.2 11 400 12 392 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Shinella zoogloeoides (Crabtreella saccharophila) 2e-76 284 mutation to A: Slightly lower activity. 64 Q 65 R 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIL_SHIZO 43.2 11 400 12 392 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Shinella zoogloeoides (Crabtreella saccharophila) 2e-76 284 mutation to A: Loss of activity. 89 C 90 C 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase SwissProt THIL_SHIZO 43.2 11 400 12 392 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Shinella zoogloeoides (Crabtreella saccharophila) 2e-76 284 mutation to G: Loss of activity. 378 C 386 C 1673680 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4c2j:D 41.6 1 398 7 393 Crystal structure of human mitochondrial 3-ketoacyl-coa thiolase in complex with coa 2e-76 284 active site 95 C 90 C 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4c2j:D 41.6 1 398 7 393 Crystal structure of human mitochondrial 3-ketoacyl-coa thiolase in complex with coa 2e-76 284 active site 351 H 356 H 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4c2j:D 41.6 1 398 7 393 Crystal structure of human mitochondrial 3-ketoacyl-coa thiolase in complex with coa 2e-76 284 active site 381 C 386 C 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4c2j:D 41.6 1 398 7 393 Crystal structure of human mitochondrial 3-ketoacyl-coa thiolase in complex with coa 2e-76 284 active site 383 G 388 G 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4c2j:D 41.6 1 398 7 393 Crystal structure of human mitochondrial 3-ketoacyl-coa thiolase in complex with coa 2e-76 284 binding coenzyme a 223 R 227 R 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4c2j:D 41.6 1 398 7 393 Crystal structure of human mitochondrial 3-ketoacyl-coa thiolase in complex with coa 2e-76 284 binding coenzyme a 246 A 249 A 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4c2j:D 41.6 1 398 7 393 Crystal structure of human mitochondrial 3-ketoacyl-coa thiolase in complex with coa 2e-76 284 binding coenzyme a 250 S 253 S 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4c2j:D 41.6 1 398 7 393 Crystal structure of human mitochondrial 3-ketoacyl-coa thiolase in complex with coa 2e-76 284 binding coenzyme a 321 A 324 A 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4c2j:D 41.6 1 398 7 393 Crystal structure of human mitochondrial 3-ketoacyl-coa thiolase in complex with coa 2e-76 284 binding coenzyme a 322 F 325 F 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 4c2j:D 41.6 1 398 7 393 Crystal structure of human mitochondrial 3-ketoacyl-coa thiolase in complex with coa 2e-76 284 binding coenzyme a 351 H 356 H 25478839 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 active site 88 C 90 C 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 active site 347 H 356 H 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 active site 377 C 386 C 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 active site 379 G 388 G 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 binding coenzyme a 88 C 90 C 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 binding coenzyme a 149 L 153 L 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 binding coenzyme a 219 K 227 R 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 binding coenzyme a 234 F 241 V 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 binding coenzyme a 242 A 249 A 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 binding coenzyme a 246 S 253 S 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 binding coenzyme a 317 A 324 A 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 binding coenzyme a 318 F 325 F 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 5f38:B 45.3 1 400 1 391 X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution 4e-76 283 binding coenzyme a 347 H 356 H 27380370 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 active site 86 C 90 C 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 active site 345 H 356 H 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 active site 375 C 386 C 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 active site 377 G 388 G 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 6 S 8 D 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 7 A 9 A 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 38 R 40 R 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 182 K 191 K 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 194 D 203 Q 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 280 V 289 V 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 281 D 290 A 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 287 T 296 M 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 331 P 342 D 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 332 S 343 A 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 334 V 345 V 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 336 V 347 P 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 2wku:A 42.5 4 400 2 389 Biosynthetic thiolase from z. Ramigera. The n316h mutant. 4e-76 283 binding D-mannose 360 F 371 Y 19842716 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 active site 87 A 90 C 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 active site 346 H 356 H 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 active site 376 C 386 C 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 active site 378 G 388 G 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 86 L 89 L 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 87 A 90 C 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 146 L 153 L 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 154 H 161 D 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 155 M 163 M 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 218 R 227 R 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 225 S 233 A 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 226 M 234 L 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 241 A 249 A 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 242 G 250 G 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 245 S 253 S 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 316 A 324 A 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 317 F 325 F 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 346 H 356 H 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 377 I 387 I 12501183 HSERO_RS19990 HSERO_RS19990 acetyl-CoA acetyltransferase PDB 1m1o:A 42.5 4 400 3 390 Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa 2e-75 281 binding acetoacetyl-coenzyme a 378 G 388 G 12501183