queryId subjectDb subjectId identity queryAlnBegin queryAlnEnd sujectAlnBegin subjectAlnEnd subjectDescription evalue bits subjectSite subjectSiteRange subjectSiteSeq querySiteRange querySiteSeq pubMedIds Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GLCP_STAES 35.4 44 470 21 437 Glucose transporter GlcP; Glucose/H(+) symporter from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 8e-73 273 mutation to N: Affects symport activity. May function as... 22 D 45 D 24127585 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GLCP_STAES 35.4 44 470 21 437 Glucose transporter GlcP; Glucose/H(+) symporter from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 8e-73 273 mutation to A: Loss of transport activity. 102 R 125 R 24127585 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GLCP_STAES 35.4 44 470 21 437 Glucose transporter GlcP; Glucose/H(+) symporter from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 8e-73 273 mutation to S: Affects symport activity. May function as... 105 I 128 L 24127585 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GLCP_STAES 35.4 44 470 21 437 Glucose transporter GlcP; Glucose/H(+) symporter from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 8e-73 273 mutation to A: Loss of transport activity. 122 E 145 E 24127585 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GLCP_STAES 35.4 44 470 21 437 Glucose transporter GlcP; Glucose/H(+) symporter from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 8e-73 273 mutation to A: Loss of transport activity. 137 Q 160 E 24127585 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GLCP_STAES 35.4 44 470 21 437 Glucose transporter GlcP; Glucose/H(+) symporter from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 8e-73 273 mutation to A: Loss of transport activity. 250 Q 282 S 24127585 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GLCP_STAES 35.4 44 470 21 437 Glucose transporter GlcP; Glucose/H(+) symporter from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 8e-73 273 mutation to A: Loss of transport activity. 251 Q 283 Q 24127585 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GLCP_STAES 35.4 44 470 21 437 Glucose transporter GlcP; Glucose/H(+) symporter from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 8e-73 273 mutation to A: Loss of transport activity. 256 N 288 N 24127585 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GLCP_STAES 35.4 44 470 21 437 Glucose transporter GlcP; Glucose/H(+) symporter from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 8e-73 273 mutation to A: Loss of transport activity. 357 W 390 W 24127585 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT1_ARATH 35.9 9 472 7 485 Inositol transporter 1 from Arabidopsis thaliana (Mouse-ear cress) 1e-70 265 mutation to AA: No effect on targeting. 481..482 ER 469 -R 22253225 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT1_ARATH 35.9 9 472 7 485 Inositol transporter 1 from Arabidopsis thaliana (Mouse-ear cress) 1e-70 265 mutation Missing: Leads to endoplasmic reticulum relocalization. 479..509 469..472 22253225 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT1_ARATH 35.9 9 472 7 485 Inositol transporter 1 from Arabidopsis thaliana (Mouse-ear cress) 1e-70 265 mutation Missing: Leads to endoplasmic reticulum relocalization. 500..509 22253225 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT1_ARATH 35.9 9 472 7 485 Inositol transporter 1 from Arabidopsis thaliana (Mouse-ear cress) 1e-70 265 mutation LLE->AAA,SSS: Leads to plasma membrane relocalization. 502..504 22253225 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: Decreases xylose transport. 24 F 42 F 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: Abolishes xylose transport. 83 G 93 G 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation R->C,H,L: Abolishes xylose transport. 133 R 125 R 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: Abolishes xylose transport. 153 E 145 E 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: Abolishes xylose transport. 160 R 152 R 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 binding ; mutation to A: Abolishes xylose transport. 168 Q 160 E 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: Abolishes xylose transport. 288 Q 282 S 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 binding 288..289 QQ 282..283 SQ 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: Strongly decreases xylose transport. 289 Q 283 Q 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 binding ; mutation to A: Abolishes xylose transport. 294 N 288 N 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: Abolishes xylose transport. 298 Y 292 Y 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: No effect on xylose transport. 325 N 319 S 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: Abolishes xylose transport. 340 G 334 G 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation R->A,W: Abolishes xylose transport. 341 R 335 R 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 binding ; mutation to A: Abolishes xylose transport. 392 W 390 W 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: Abolishes xylose transport. 397 E 395 E 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: Strongly decreases xylose transport. 404 R 402 R 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 binding 415 Q 413 F 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt XYLE_ECOLI 30.8 25 467 7 475 D-xylose-proton symporter; D-xylose transporter from Escherichia coli (strain K12) 3e-54 211 mutation to A: Strongly decreases xylose transport. 416 W 414 W 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gc0:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to 6-bromo-6-deoxy-d-glucose 3e-54 211 binding 6-bromo-6-deoxy-beta-D-glucopyranose 164 Q 160 E 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gc0:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to 6-bromo-6-deoxy-d-glucose 3e-54 211 binding 6-bromo-6-deoxy-beta-D-glucopyranose 284 Q 282 S 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gc0:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to 6-bromo-6-deoxy-d-glucose 3e-54 211 binding 6-bromo-6-deoxy-beta-D-glucopyranose 290 N 288 N 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gc0:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to 6-bromo-6-deoxy-d-glucose 3e-54 211 binding 6-bromo-6-deoxy-beta-D-glucopyranose 293 L 291 M 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gc0:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to 6-bromo-6-deoxy-d-glucose 3e-54 211 binding 6-bromo-6-deoxy-beta-D-glucopyranose 388 W 390 W 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gbz:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-glucose 3e-54 211 binding beta-D-glucopyranose 164 Q 160 E 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gbz:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-glucose 3e-54 211 binding beta-D-glucopyranose 284 Q 282 S 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gbz:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-glucose 3e-54 211 binding beta-D-glucopyranose 290 N 288 N 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gbz:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-glucose 3e-54 211 binding beta-D-glucopyranose 388 W 390 W 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gby:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-xylose 3e-54 211 binding beta-D-xylopyranose 164 Q 160 E 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gby:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-xylose 3e-54 211 binding beta-D-xylopyranose 284 Q 282 S 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gby:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-xylose 3e-54 211 binding beta-D-xylopyranose 290 N 288 N 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4gby:A 30.8 25 467 3 471 The structure of the mfs (major facilitator superfamily) proton:xylose symporter xyle bound to d-xylose 3e-54 211 binding beta-D-xylopyranose 388 W 390 W 23075985 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT2_ARATH 34.2 10 350 10 355 Probable inositol transporter 2 from Arabidopsis thaliana (Mouse-ear cress) 6e-49 193 C→A: Strongly decreased nickel inhibition; when associated with A-402,...; C→S: No effect on inostol transport or nickel inhibition.... 399 20230529 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT2_ARATH 34.2 10 350 10 355 Probable inositol transporter 2 from Arabidopsis thaliana (Mouse-ear cress) 6e-49 193 C→A: Strongly decreased nickel inhibition; when associated with A-399,... 402 20230529 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT2_ARATH 34.2 10 350 10 355 Probable inositol transporter 2 from Arabidopsis thaliana (Mouse-ear cress) 6e-49 193 C→A: Strongly decreased nickel inhibition; when associated with A-399,...; C→S: No effect on inostol transport or nickel inhibition;... 410 20230529 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT2_ARATH 34.2 10 350 10 355 Probable inositol transporter 2 from Arabidopsis thaliana (Mouse-ear cress) 6e-49 193 C→A: Strongly decreased nickel inhibition; when associated with A-399,... 413 20230529 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT4_ARATH 34.2 27 356 26 363 Inositol transporter 4; Myo-inositol-proton symporter INT4; Protein INOSITOL TRANSPORTER 4 from Arabidopsis thaliana (Mouse-ear cress) 1e-44 179 LLE→AAA: No effect on targeting. 559..561 22253225 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT4_ARATH 34.2 27 356 26 363 Inositol transporter 4; Myo-inositol-proton symporter INT4; Protein INOSITOL TRANSPORTER 4 from Arabidopsis thaliana (Mouse-ear cress) 1e-44 179 mutation Missing: No effect on targeting. 559..582 22253225 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT4_ARATH 34.2 27 356 26 363 Inositol transporter 4; Myo-inositol-proton symporter INT4; Protein INOSITOL TRANSPORTER 4 from Arabidopsis thaliana (Mouse-ear cress) 1e-44 179 FK→AA: No effect on targeting. 564..565 22253225 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt INT4_ARATH 34.2 27 356 26 363 Inositol transporter 4; Myo-inositol-proton symporter INT4; Protein INOSITOL TRANSPORTER 4 from Arabidopsis thaliana (Mouse-ear cress) 1e-44 179 RRREKK→AAAAAA: No effect on targeting. 570..575 22253225 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt HXT7_YEAST 28.9 3 467 39 525 High-affinity hexose transporter HXT7 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 8e-43 173 modified: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in... 560 12872131 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt HXT6_YEAST 28.9 3 467 39 525 High-affinity hexose transporter HXT6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 1e-42 172 modified: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in... 560 12872131 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT8_SCHPO 28.4 36 468 14 465 Probable high-affinity hexose transporter ght8, mitochondrial; Hexose transporter 8 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 5e-42 170 modified: Phosphoserine 519 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT8_SCHPO 28.4 36 468 14 465 Probable high-affinity hexose transporter ght8, mitochondrial; Hexose transporter 8 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 5e-42 170 modified: Phosphothreonine 523 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT8_SCHPO 28.4 36 468 14 465 Probable high-affinity hexose transporter ght8, mitochondrial; Hexose transporter 8 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 5e-42 170 modified: Phosphothreonine 526 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT8_SCHPO 28.4 36 468 14 465 Probable high-affinity hexose transporter ght8, mitochondrial; Hexose transporter 8 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 5e-42 170 modified: Phosphoserine 527 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT8_SCHPO 28.4 36 468 14 465 Probable high-affinity hexose transporter ght8, mitochondrial; Hexose transporter 8 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 5e-42 170 modified: Phosphoserine 528 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT8_SCHPO 28.4 36 468 14 465 Probable high-affinity hexose transporter ght8, mitochondrial; Hexose transporter 8 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 5e-42 170 modified: Phosphoserine 529 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT8_SCHPO 28.4 36 468 14 465 Probable high-affinity hexose transporter ght8, mitochondrial; Hexose transporter 8 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 5e-42 170 modified: Phosphoserine 537 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT2_SCHPO 28.5 36 468 18 469 High-affinity glucose transporter ght2; Hexose transporter 2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 6e-42 170 modified: Phosphoserine 507 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT2_SCHPO 28.5 36 468 18 469 High-affinity glucose transporter ght2; Hexose transporter 2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 6e-42 170 modified: Phosphoserine 515 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT2_SCHPO 28.5 36 468 18 469 High-affinity glucose transporter ght2; Hexose transporter 2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 6e-42 170 modified: Phosphoserine 519 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT2_SCHPO 28.5 36 468 18 469 High-affinity glucose transporter ght2; Hexose transporter 2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 6e-42 170 modified: Phosphoserine 520 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT2_SCHPO 28.5 36 468 18 469 High-affinity glucose transporter ght2; Hexose transporter 2 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 6e-42 170 modified: Phosphotyrosine 523 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 26 T 46 T 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 66 A - 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 69 S 75 L 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 157 Q 160 E 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 164 I 167 Q 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 278 Q 282 S 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 279 Q 283 Q 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 284 N 288 N 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 313 N 319 S 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 375 F 381 M 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 384 W 390 W 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 411 N 417 N 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 412 F 418 V 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7crz:A 27.4 34 472 14 465 Crystal structure of human glucose transporter glut3 bound with c3361 4e-41 167 binding (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol 415 G 421 G 33402433 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding beta-D-glucopyranose 159 Q 160 E 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding beta-D-glucopyranose 166 I 167 Q 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding beta-D-glucopyranose 280 Q 282 S 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding beta-D-glucopyranose 281 Q 283 Q 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding beta-D-glucopyranose 286 N 288 N 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding beta-D-glucopyranose 377 F 381 M 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding beta-D-glucopyranose 386 W 390 W 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding alpha-D-glucopyranose 159 Q 160 E 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding alpha-D-glucopyranose 162 I 163 I 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding alpha-D-glucopyranose 166 I 167 Q 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding alpha-D-glucopyranose 280 Q 282 S 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding alpha-D-glucopyranose 281 Q 283 Q 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding alpha-D-glucopyranose 286 N 288 N 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 4zw9:A 27.4 34 472 16 467 Crystal structure of human glut3 bound to d-glucose in the outward- occluded conformation at 1.5 angstrom 4e-41 167 binding alpha-D-glucopyranose 386 W 390 W 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 21 F 42 F 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 25 T 46 T 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 29 N 50 N 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 156 Q 160 E 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 163 I 167 Q 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 278 Q 283 Q 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 286 F 291 M 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 308 A 315 N 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 312 N 319 S 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 374 F 381 M 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 375 E 382 Q 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 406 N 413 F 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 407 W 414 W 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7sps:A 27.4 34 472 13 464 Crystal structure of human glucose transporter glut3 bound with exofacial inhibitor sa47 4e-41 167 binding methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate 410 N 417 N 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GTR3_HUMAN 27.4 34 472 16 467 Solute carrier family 2, facilitated glucose transporter member 3; Glucose transporter type 3, brain; GLUT-3 from Homo sapiens (Human) 5e-41 167 binding 159 Q 160 E 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GTR3_HUMAN 27.4 34 472 16 467 Solute carrier family 2, facilitated glucose transporter member 3; Glucose transporter type 3, brain; GLUT-3 from Homo sapiens (Human) 5e-41 167 Important for selectivity against fructose; mutation to HVA: Confers moderate fructose transport activity. 277..279 QLS 279..281 AVT 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GTR3_HUMAN 27.4 34 472 16 467 Solute carrier family 2, facilitated glucose transporter member 3; Glucose transporter type 3, brain; GLUT-3 from Homo sapiens (Human) 5e-41 167 binding 280..281 QQ 282..283 SQ 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GTR3_HUMAN 27.4 34 472 16 467 Solute carrier family 2, facilitated glucose transporter member 3; Glucose transporter type 3, brain; GLUT-3 from Homo sapiens (Human) 5e-41 167 binding 286 N 288 N 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GTR3_HUMAN 27.4 34 472 16 467 Solute carrier family 2, facilitated glucose transporter member 3; Glucose transporter type 3, brain; GLUT-3 from Homo sapiens (Human) 5e-41 167 binding 315 N 319 S 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GTR3_HUMAN 27.4 34 472 16 467 Solute carrier family 2, facilitated glucose transporter member 3; Glucose transporter type 3, brain; GLUT-3 from Homo sapiens (Human) 5e-41 167 binding 378 E 382 Q 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GTR3_HUMAN 27.4 34 472 16 467 Solute carrier family 2, facilitated glucose transporter member 3; Glucose transporter type 3, brain; GLUT-3 from Homo sapiens (Human) 5e-41 167 binding 386 W 390 W 26176916 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt HXT4_YEAST 28.6 3 467 44 531 Low-affinity glucose transporter HXT4; Low-affinity glucose transporter LGT1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 8e-41 166 modified: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in... 45 K 4 N 14557538 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7spt:A 27.7 34 472 16 467 Crystal structure of exofacial state human glucose transporter glut3 1e-40 166 binding alpha-D-glucopyranose 24 F 42 F 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7spt:A 27.7 34 472 16 467 Crystal structure of exofacial state human glucose transporter glut3 1e-40 166 binding alpha-D-glucopyranose 159 Q 160 E 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7spt:A 27.7 34 472 16 467 Crystal structure of exofacial state human glucose transporter glut3 1e-40 166 binding alpha-D-glucopyranose 166 I 167 Q 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7spt:A 27.7 34 472 16 467 Crystal structure of exofacial state human glucose transporter glut3 1e-40 166 binding alpha-D-glucopyranose 280 Q 282 S 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7spt:A 27.7 34 472 16 467 Crystal structure of exofacial state human glucose transporter glut3 1e-40 166 binding alpha-D-glucopyranose 281 Q 283 Q 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7spt:A 27.7 34 472 16 467 Crystal structure of exofacial state human glucose transporter glut3 1e-40 166 binding alpha-D-glucopyranose 286 N 288 N 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT PDB 7spt:A 27.7 34 472 16 467 Crystal structure of exofacial state human glucose transporter glut3 1e-40 166 binding alpha-D-glucopyranose 386 W 390 W 35552392 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT5_SCHPO 27.8 36 468 14 465 High-affinity glucose transporter ght5; Hexose transporter 5 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 1e-40 166 modified: Phosphoserine 528 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt GHT5_SCHPO 27.8 36 468 14 465 High-affinity glucose transporter ght5; Hexose transporter 5 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 1e-40 166 modified: Phosphoserine 537 18257517 Pf6N2E2_883 Major myo-inositol transporter IolT SwissProt HXT5_YEAST 29.5 37 468 95 547 Probable glucose transporter HXT5 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 3e-40 164 modified: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in... 61 12872131