queryId subjectDb subjectId identity queryAlnBegin queryAlnEnd sujectAlnBegin subjectAlnEnd subjectDescription evalue bits subjectSite subjectSiteRange subjectSiteSeq querySiteRange querySiteSeq pubMedIds PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3bfj:A 43.0 15 382 14 382 Crystal structure analysis of 1,3-propanediol oxidoreductase 4e-69 260 binding fe (ii) ion 193 D 192 D 19011020 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3bfj:A 43.0 15 382 14 382 Crystal structure analysis of 1,3-propanediol oxidoreductase 4e-69 260 binding fe (ii) ion 197 H 196 H 19011020 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3bfj:A 43.0 15 382 14 382 Crystal structure analysis of 1,3-propanediol oxidoreductase 4e-69 260 binding fe (ii) ion 262 H 261 H 19011020 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3bfj:A 43.0 15 382 14 382 Crystal structure analysis of 1,3-propanediol oxidoreductase 4e-69 260 binding fe (ii) ion 276 H 275 H 19011020 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 modified: Initiator methionine, Removed 1 M 1 M 2935393 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 39 D 39 D 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 71 N 69 D 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 98 G 96 G 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 99 S 97 S 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 138 T 136 T 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 139 T 137 T 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 147 T 145 T 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 149 F 147 V 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 160 K 158 K 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 179 L 177 M 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 182 G 180 T 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 183 M 181 C 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 194 D 192 D 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 198 H 196 H 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 263 H 261 H 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding 267 H 265 Y 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH2_ZYMMO 37.8 1 382 1 383 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; ADH II; EC 1.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) 1e-68 258 binding ; binding 277 H 275 H 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding fe (ii) ion 193 D 192 D 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding fe (ii) ion 197 H 196 H 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding fe (ii) ion 262 H 261 H 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding fe (ii) ion 276 H 275 H 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 38 D 39 D 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 40 F 41 A 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 41 M 42 L 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 70 N 69 D 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 96 G 95 G 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 97 G 96 G 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 98 S 97 S 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 137 T 136 T 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 138 T 137 T 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 148 F 147 V 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 150 I 149 I 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 181 G 180 T 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 182 M 181 C 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 186 L 185 V 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3ox4:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 complexed with NAD cofactor 3e-68 257 binding nicotinamide-adenine-dinucleotide 276 H 275 H 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3owo:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 with and without NAD cofactor 3e-68 257 binding fe (ii) ion 193 D 192 D 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3owo:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 with and without NAD cofactor 3e-68 257 binding fe (ii) ion 197 H 196 H 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3owo:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 with and without NAD cofactor 3e-68 257 binding fe (ii) ion 262 H 261 H 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3owo:A 37.8 4 382 3 382 Structures of iron-dependent alcohol dehydrogenase 2 from zymomonas mobilis zm4 with and without NAD cofactor 3e-68 257 binding fe (ii) ion 276 H 275 H 21295587 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 39 D 39 D 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 41 T 41 A 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 42 L 42 L 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 70 P 68 P 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 97 G 95 G 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 98 G 96 G 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 99 S 97 S 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 102 D 100 D 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 140 T 136 T 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 141 T 137 T 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 144 T 140 T 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 149 T 145 T 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 151 N 147 V 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 153 V 149 I 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 162 K 158 K 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 184 G 180 T 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 185 C 181 C 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 189 L 185 V 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding nicotinamide-adenine-dinucleotide 277 H 275 H 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding zinc ion 196 D 192 D 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding zinc ion 200 H 196 H 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding zinc ion 263 H 261 H 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 5br4:A 39.0 15 382 15 383 E. Coli lactaldehyde reductase (fuco) m185c mutant 2e-62 238 binding zinc ion 277 H 275 H 26512129 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt MEDH_BACMT 36.0 3 381 1 380 NAD-dependent methanol dehydrogenase; MDH; MEDH; Type 3 alcohol dehydrogenase; EC 1.1.1.244 from Bacillus methanolicus 5e-62 236 modified: Initiator methionine, Removed 1 M 3 L 1644761,1995642 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt MEDH_BACMT 36.0 3 381 1 380 NAD-dependent methanol dehydrogenase; MDH; MEDH; Type 3 alcohol dehydrogenase; EC 1.1.1.244 from Bacillus methanolicus 5e-62 236 mutation to A: Shows a reduced dehydrogenase activity. 13 G 15 G 12351635 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt MEDH_BACMT 36.0 3 381 1 380 NAD-dependent methanol dehydrogenase; MDH; MEDH; Type 3 alcohol dehydrogenase; EC 1.1.1.244 from Bacillus methanolicus 5e-62 236 mutation to A: Shows almost the same dehydrogenase activity... 15 G 17 G 12351635 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt MEDH_BACMT 36.0 3 381 1 380 NAD-dependent methanol dehydrogenase; MDH; MEDH; Type 3 alcohol dehydrogenase; EC 1.1.1.244 from Bacillus methanolicus 5e-62 236 mutation to N: Shows almost the same dehydrogenase activity... 88 D 88 D 12351635 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt MEDH_BACMT 36.0 3 381 1 380 NAD-dependent methanol dehydrogenase; MDH; MEDH; Type 3 alcohol dehydrogenase; EC 1.1.1.244 from Bacillus methanolicus 5e-62 236 mutation to A: Shows a 10-fold decreased affinity for... 95 G 95 G 12351635 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt MEDH_BACMT 36.0 3 381 1 380 NAD-dependent methanol dehydrogenase; MDH; MEDH; Type 3 alcohol dehydrogenase; EC 1.1.1.244 from Bacillus methanolicus 5e-62 236 mutation to G: Shows an increase of the dehydrogenase...; mutation to T: Shows an increase of the dehydrogenase... 97 S 97 S 12351635 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt MEDH_BACMT 36.0 3 381 1 380 NAD-dependent methanol dehydrogenase; MDH; MEDH; Type 3 alcohol dehydrogenase; EC 1.1.1.244 from Bacillus methanolicus 5e-62 236 mutation to N: Loss of dehydrogenase activity. It still... 100 D 100 D 12351635 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt MEDH_BACMT 36.0 3 381 1 380 NAD-dependent methanol dehydrogenase; MDH; MEDH; Type 3 alcohol dehydrogenase; EC 1.1.1.244 from Bacillus methanolicus 5e-62 236 mutation to R: Loss of dehydrogenase activity. It does... 103 K 103 K 12351635 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 37 D 39 D 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 39 T 41 A 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 40 L 42 L 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 95 G 95 G 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 96 G 96 G 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 97 S 97 S 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 138 T 136 T 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 139 T 137 T 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 142 T 140 T 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 160 K 158 K 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 182 G 180 T 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 183 M 181 C 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 187 L 185 V 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding adenosine-5-diphosphoribose 275 H 275 H 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding 2-(3,4-dimethoxyphenyl)ethanamide 149 G 147 V 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding 2-(3,4-dimethoxyphenyl)ethanamide 164 V 162 V 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding 2-(3,4-dimethoxyphenyl)ethanamide 198 H 196 H 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding 2-(3,4-dimethoxyphenyl)ethanamide 252 F 252 F 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding 2-(3,4-dimethoxyphenyl)ethanamide 253 S 253 G 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding 2-(3,4-dimethoxyphenyl)ethanamide 261 H 261 H 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding 2-(3,4-dimethoxyphenyl)ethanamide 360 C 361 L 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding fe (iii) ion 194 D 192 D 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding fe (iii) ion 198 H 196 H 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding fe (iii) ion 261 H 261 H 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlq:AAA 39.0 15 382 13 381 Lactaldehyde reductase 2e-61 234 binding fe (iii) ion 275 H 275 H 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding fe (iii) ion 195 D 192 D 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding fe (iii) ion 199 H 196 H 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding fe (iii) ion 262 H 261 H 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding fe (iii) ion 276 H 275 H 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 38 D 39 D 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 40 T 41 A 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 41 L 42 L 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 96 G 95 G 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 97 G 96 G 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 98 S 97 S 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 139 T 136 T 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 140 T 137 T 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 152 V 149 I 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 161 K 158 K 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 183 G 180 T 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 184 M 181 C 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 188 L 185 V 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 195 D 192 D 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 199 H 196 H 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 262 H 261 H 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 2bi4:A 38.7 15 382 14 382 Lactaldehyde:1,2-propanediol oxidoreductase of escherichia coli 4e-61 233 binding nicotinamide-adenine-dinucleotide 276 H 275 H 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt FUCO_ECOLI 38.7 15 382 14 382 Lactaldehyde reductase; Propanediol oxidoreductase; EC 1.1.1.77 from Escherichia coli (strain K12) 4e-61 233 mutation to D: No effect on enzyme activity. 16 G 17 G 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt FUCO_ECOLI 38.7 15 382 14 382 Lactaldehyde reductase; Propanediol oxidoreductase; EC 1.1.1.77 from Escherichia coli (strain K12) 4e-61 233 mutation to G: Enzyme can now use NADP. 38 D 39 D 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt FUCO_ECOLI 38.7 15 382 14 382 Lactaldehyde reductase; Propanediol oxidoreductase; EC 1.1.1.77 from Escherichia coli (strain K12) 4e-61 233 mutation to E: Loss of NAD binding and enzyme... 96 G 95 G 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt FUCO_ECOLI 38.7 15 382 14 382 Lactaldehyde reductase; Propanediol oxidoreductase; EC 1.1.1.77 from Escherichia coli (strain K12) 4e-61 233 mutation to L: Complete loss of iron-binding. 195 D 192 D 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt FUCO_ECOLI 38.7 15 382 14 382 Lactaldehyde reductase; Propanediol oxidoreductase; EC 1.1.1.77 from Escherichia coli (strain K12) 4e-61 233 mutation H->A,F: Complete loss of iron-binding. 199 H 196 H 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt FUCO_ECOLI 38.7 15 382 14 382 Lactaldehyde reductase; Propanediol oxidoreductase; EC 1.1.1.77 from Escherichia coli (strain K12) 4e-61 233 MANRMILNE→M: Loss of enzyme activity, loss of dimerization. 1..9 15995211 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding fe (iii) ion 194 D 192 D 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding fe (iii) ion 198 H 196 H 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding fe (iii) ion 261 H 261 H 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding fe (iii) ion 275 H 275 H 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 37 D 39 D 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 39 T 41 A 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 40 L 42 L 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 69 N 69 D 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 95 G 95 G 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 96 G 96 G 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 97 S 97 S 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 100 D 100 D 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 138 T 136 T 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 139 T 137 T 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 142 T 140 T 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 147 T 145 T 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 149 N 147 V 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 160 K 158 K 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 187 L 185 V 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 198 H 196 H 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 7qlg:AAA 38.7 15 382 13 381 Lactaldehyde reductase 5e-61 233 binding 1,4-dihydronicotinamide adenine dinucleotide 275 H 275 H 37261425 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 38 D 39 D PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 40 T 41 A PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 41 L 42 L PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 70 N 69 D PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 96 G 95 G PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 97 G 96 G PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 98 S 97 S PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 139 T 136 T PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 140 T 137 T PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 143 T 140 T PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 152 V 149 I PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 161 K 158 K PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 183 G 180 T PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 184 M 181 C PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 188 L 185 V PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding adenosine-5-diphosphoribose 276 H 275 H PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding fe (ii) ion 258 L 257 V PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding fe (ii) ion 361 C 361 L PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding zinc ion 195 D 192 D PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding zinc ion 199 H 196 H PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding zinc ion 262 H 261 H PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1rrm:A 38.7 15 382 14 382 Crystal structure of lactaldehyde reductase 5e-61 233 binding zinc ion 276 H 275 H PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3zdr:A 35.8 2 382 1 400 Structure of the alcohol dehydrogenase (adh) domain of a bifunctional adhe dehydrogenase from geobacillus thermoglucosidasius ncimb 11955 3e-58 224 binding zinc ion 203 D 192 D 24100328 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3zdr:A 35.8 2 382 1 400 Structure of the alcohol dehydrogenase (adh) domain of a bifunctional adhe dehydrogenase from geobacillus thermoglucosidasius ncimb 11955 3e-58 224 binding zinc ion 207 H 196 H 24100328 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3zdr:A 35.8 2 382 1 400 Structure of the alcohol dehydrogenase (adh) domain of a bifunctional adhe dehydrogenase from geobacillus thermoglucosidasius ncimb 11955 3e-58 224 binding zinc ion 272 H 261 H 24100328 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 3zdr:A 35.8 2 382 1 400 Structure of the alcohol dehydrogenase (adh) domain of a bifunctional adhe dehydrogenase from geobacillus thermoglucosidasius ncimb 11955 3e-58 224 binding zinc ion 286 H 275 H 24100328 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt 4HBDH_CUPNE 34.6 17 377 15 377 4-hydroxybutyrate dehydrogenase; 4HbD; Gamma-hydroxybutyrate dehydrogenase; GHBDH; EC 1.1.1.61 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha) 2e-50 198 mutation to A: Retains very low activity. 193 D 192 D 31981617 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt 4HBDH_CUPNE 34.6 17 377 15 377 4-hydroxybutyrate dehydrogenase; 4HbD; Gamma-hydroxybutyrate dehydrogenase; GHBDH; EC 1.1.1.61 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha) 2e-50 198 mutation to A: Loss of activity. 197 H 196 H 31981617 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt 4HBDH_CUPNE 34.6 17 377 15 377 4-hydroxybutyrate dehydrogenase; 4HbD; Gamma-hydroxybutyrate dehydrogenase; GHBDH; EC 1.1.1.61 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha) 2e-50 198 mutation to A: Loss of activity. 261 H 261 H 31981617 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt 4HBDH_CUPNE 34.6 17 377 15 377 4-hydroxybutyrate dehydrogenase; 4HbD; Gamma-hydroxybutyrate dehydrogenase; GHBDH; EC 1.1.1.61 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha) 2e-50 198 mutation to A: 75% decrease in Vmax. Optimum pH...; mutation to C: 95% decrease in Vmax. Optimum pH...; mutation to D: Retains very low activity.; mutation to Y: Loss of activity. 265 H 265 Y 31981617 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt 4HBDH_CUPNE 34.6 17 377 15 377 4-hydroxybutyrate dehydrogenase; 4HbD; Gamma-hydroxybutyrate dehydrogenase; GHBDH; EC 1.1.1.61 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha) 2e-50 198 mutation to A: Retains very low activity. 280 H 275 H 31981617 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jkp:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+ 3e-47 187 binding nicotinamide-adenine-dinucleotide 42 F 42 L 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jkp:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+ 3e-47 187 binding nicotinamide-adenine-dinucleotide 96 G 96 G 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jkp:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+ 3e-47 187 binding nicotinamide-adenine-dinucleotide 100 D 100 D 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jkp:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+ 3e-47 187 binding nicotinamide-adenine-dinucleotide 137 T 136 T 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jkp:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+ 3e-47 187 binding nicotinamide-adenine-dinucleotide 138 T 137 T 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jkp:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+ 3e-47 187 binding nicotinamide-adenine-dinucleotide 141 T 140 T 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jkp:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+ 3e-47 187 binding nicotinamide-adenine-dinucleotide 143 S 142 S 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jkp:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+ 3e-47 187 binding nicotinamide-adenine-dinucleotide 146 T 145 T 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jkp:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+ 3e-47 187 binding nicotinamide-adenine-dinucleotide 181 S 180 T 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jkp:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+ 3e-47 187 binding nicotinamide-adenine-dinucleotide 182 V 181 C 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jkp:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense in complex with NAD+ 3e-47 187 binding nicotinamide-adenine-dinucleotide 183 P 182 P 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jko:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense 3e-47 187 binding zinc ion 193 D 192 D 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jko:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense 3e-47 187 binding zinc ion 262 H 261 H 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6jko:A 33.6 35 379 35 370 Crystal structure of sulfoacetaldehyde reductase from bifidobacterium kashiwanohense 3e-47 187 binding zinc ion 276 H 275 H 31123167 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding fe (iii) ion 189 D 192 D 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding fe (iii) ion 193 H 196 H 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding fe (iii) ion 256 H 261 H 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding fe (iii) ion 270 H 275 H 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 68 E 68 P 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 69 N 69 D 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 95 G 95 G 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 96 G 96 G 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 97 S 97 S 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 100 D 100 D 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 136 T 136 T 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 137 T 137 T 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 140 T 140 T 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 142 S 142 S 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 147 Y 147 V 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 149 I 149 I 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 157 K 158 K 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 177 S 180 T 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 178 M 181 C 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 182 L 185 V 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 189 D 192 D 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 193 H 196 H 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 270 H 275 H 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 38 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1o2d:A 39.8 59 306 59 301 Crystal structure of alcohol dehydrogenase, iron-containing (tm0920) from thermotoga maritima at 1.30 a resolution 9e-42 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 39 14705036 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 69 E 68 P 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 70 N 69 D 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 96 G 95 G 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 97 G 96 G 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 98 S 97 S 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 101 D 100 D 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 137 T 136 T 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 138 T 137 T 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 141 T 140 T 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 143 S 142 S 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 146 T 145 T 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 148 Y 147 V 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 150 I 149 I 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 158 K 158 K 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 178 S 180 T 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 179 M 181 C 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 183 L 185 V 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 190 D 192 D 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 194 H 196 H 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 271 H 275 H 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding zinc ion 190 D 192 D 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding zinc ion 194 H 196 H 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding zinc ion 257 H 261 H 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding zinc ion 271 H 275 H 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 39 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 1vhd:A 39.8 59 306 60 302 Crystal structure of an iron containing alcohol dehydrogenase 1e-41 169 binding nadp nicotinamide-adenine-dinucleotide phosphate 40 16021622 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding fe (iii) ion 204 D 192 D 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding fe (iii) ion 208 H 196 H 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding fe (iii) ion 274 H 261 H 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding fe (iii) ion 288 H 275 H 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 38 D 39 D 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 40 F 41 A 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 69 A 68 P 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 70 D 69 D 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 96 G 95 G 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 97 G 96 G 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 98 S 97 S 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 148 T 136 T 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 149 T 137 T 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 152 T 140 T 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 161 V 149 I 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 197 L 185 V 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) PDB 6scg:A 34.5 35 345 34 359 Structure of adhe form 1 2e-39 161 binding nicotinamide-adenine-dinucleotide 278 H 265 Y 32880589 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH_THEBA 32.9 69 382 67 376 Alcohol dehydrogenase; EC 1.1.1.1 from Thermococcus barophilus 2e-38 158 mutation to A: Disrupts the overall structure of the... 195 D 192 D 33428959 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH_THEBA 32.9 69 382 67 376 Alcohol dehydrogenase; EC 1.1.1.1 from Thermococcus barophilus 2e-38 158 mutation to A: Disrupts the overall structure of the... 199 H 196 H 33428959 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH_THEBA 32.9 69 382 67 376 Alcohol dehydrogenase; EC 1.1.1.1 from Thermococcus barophilus 2e-38 158 mutation to A: Disrupts the overall structure of the... 262 H 261 H 33428959 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH_THEBA 32.9 69 382 67 376 Alcohol dehydrogenase; EC 1.1.1.1 from Thermococcus barophilus 2e-38 158 mutation to A: Disrupts the overall structure of the... 266 H 265 Y 33428959 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADH_THEBA 32.9 69 382 67 376 Alcohol dehydrogenase; EC 1.1.1.1 from Thermococcus barophilus 2e-38 158 mutation to A: Disrupts the overall structure of the... 274 H 275 H 33428959 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 487 D 39 D 32523125 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 519 D 69 D 32523125 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 546..550 GSPMD 96..100 GSAID 32523125 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 mutation to K: Partially restores protein stability and resistance... 568 E 117 D 10922373 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 610 V 149 I 32523125 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 619 K 158 K 32523125 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 653 D 192 D 32188856 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 657 H 196 H 32188856 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 mutation F->A,E,V: Disrupts spirosome formation. Affects the forward activity... 670 F 209 I 31586059 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 723 H 261 H 32188856 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 737 H 275 H 32188856 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 modified: Initiator methionine, Removed 1 2015910,2695398,7521508 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 110..115 32523125 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 195 32523125 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 213 32523125 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 A→T: Shows aerobic growth ability on ethanol. Shows 5-6... 267 10922373 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 335 32523125 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 modified: N6-acetyllysine 358 18723842 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 binding 419 32523125 PfGW456L13_1214 Alcohol dehydrogenase (EC 1.1.1.1) SwissProt ADHE_ECOLI 33.1 35 345 483 822 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) 5e-38 157 mutation Missing: Can form dimers, but does not assemble... 446..449 32188856