queryId subjectDb subjectId identity queryAlnBegin queryAlnEnd sujectAlnBegin subjectAlnEnd subjectDescription evalue bits subjectSite subjectSiteRange subjectSiteSeq querySiteRange querySiteSeq pubMedIds PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt HDHA_CLOSR 37.5 5 257 1 254 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NADP-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.- from Clostridium sardiniense (Clostridium absonum) 2e-39 160 binding 13..18 SSTRGI 17..22 GAGSGI 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt HDHA_CLOSR 37.5 5 257 1 254 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NADP-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.- from Clostridium sardiniense (Clostridium absonum) 2e-39 160 binding ; mutation to D: Loss of catalytic activity. 38 R 42 L 24810359,26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt HDHA_CLOSR 37.5 5 257 1 254 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NADP-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.- from Clostridium sardiniense (Clostridium absonum) 2e-39 160 binding 63..64 NA 64..65 DV 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt HDHA_CLOSR 37.5 5 257 1 254 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NADP-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.- from Clostridium sardiniense (Clostridium absonum) 2e-39 160 binding 90 N 91 N 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt HDHA_CLOSR 37.5 5 257 1 254 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NADP-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.- from Clostridium sardiniense (Clostridium absonum) 2e-39 160 binding 145 T 148 S 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt HDHA_CLOSR 37.5 5 257 1 254 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NADP-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.- from Clostridium sardiniense (Clostridium absonum) 2e-39 160 binding ; binding 158 Y 161 Y 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt HDHA_CLOSR 37.5 5 257 1 254 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NADP-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.- from Clostridium sardiniense (Clostridium absonum) 2e-39 160 binding 162 K 165 K 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt HDHA_CLOSR 37.5 5 257 1 254 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NADP-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.- from Clostridium sardiniense (Clostridium absonum) 2e-39 160 binding 191..195 IGTRA 194..198 IRTPA 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt HDHA_CLOSR 37.5 5 257 1 254 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NADP-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.- from Clostridium sardiniense (Clostridium absonum) 2e-39 160 mutation Missing: 5-fold reduction in catalytic efficiency. 261..262 24810359 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 active site 21 G 21 G PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 active site 143 S 148 S PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 active site 154 Q 158 Q PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 active site 157 Y 161 Y PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 active site 161 K 165 K PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 17 G 17 G PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 19 A 19 G PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 20 S 20 S PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 21 G 21 G PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 22 I 22 I PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 41 D 41 D PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 42 I 42 L PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 61 V 63 V PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 62 D 64 D PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 63 V 65 V PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 89 N 91 N PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 141 T 146 T PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 157 Y 161 Y PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 161 K 165 K PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 187 P 191 P PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 189 P 193 V PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4wec:A 37.6 3 258 3 258 Crystal structure of a short chain dehydrogenase from mycobacterium smegmatis 2e-39 160 binding nicotinamide-adenine-dinucleotide 190 V 194 I PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 active site 16 G 21 G 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 active site 144 T 148 S 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 active site 152 I 156 I 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 active site 157 Y 161 Y 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 active site 161 K 165 K 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 active site 193 R 197 P 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 12 S 17 G 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 14 T 19 G 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 15 R 20 S 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 16 G 21 G 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 17 I 22 I 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 37 R 42 L 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 61 F 63 V 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 62 N 64 D 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 89 N 91 N 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 90 Y 94 Y 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 91 G 95 R 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 157 Y 161 Y 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 161 K 165 K 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 187 P 191 P 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 188 G 192 G 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 190 I 194 I 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 192 T 196 T 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 193 R 197 P 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 194 A 198 A 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding nadp nicotinamide-adenine-dinucleotide phosphate 195 A 199 M 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding taurochenodeoxycholic acid 93 T 97 P 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding taurochenodeoxycholic acid 144 T 148 S 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding taurochenodeoxycholic acid 146 G 150 S 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding taurochenodeoxycholic acid 154 R 158 Q 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding taurochenodeoxycholic acid 157 Y 161 Y 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding taurochenodeoxycholic acid 188 G 192 G 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding taurochenodeoxycholic acid 198 N 202 W 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding taurochenodeoxycholic acid 199 M 203 A 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 5epo:A 37.6 6 257 1 253 The three-dimensional structure of clostridium absonum 7alpha- hydroxysteroid dehydrogenase 3e-39 160 binding taurochenodeoxycholic acid 203 F 207 M 26961171 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHRS6_MOUSE 39.0 7 253 3 244 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 from Mus musculus (Mouse) 2e-37 154 active site, Proton acceptor; mutation to F: Loss of function. 147 Y 161 Y 20550936 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHRS6_RAT 39.0 7 253 3 244 Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1; EC 1.1.1.-; EC 1.1.1.30; EC 1.1.1.104 from Rattus norvegicus (Rat) 5e-37 152 mutation to F: Loss of function. 147 Y 161 Y 35150746 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 active site 18 G 21 G 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 active site 111 N 120 N 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 active site 139 S 148 S 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 active site 149 Q 158 Q 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 active site 152 Y 161 Y 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 active site 156 K 165 K 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding acetoacetyl-coenzyme a 93 D 102 D 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding acetoacetyl-coenzyme a 98 K 107 N 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding acetoacetyl-coenzyme a 139 S 148 S 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding acetoacetyl-coenzyme a 146 N 155 E 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding acetoacetyl-coenzyme a 147 V 156 I 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding acetoacetyl-coenzyme a 149 Q 158 Q 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding acetoacetyl-coenzyme a 152 Y 161 Y 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding acetoacetyl-coenzyme a 184 F 193 V 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding acetoacetyl-coenzyme a 189 M 199 M 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding acetoacetyl-coenzyme a 200 K 210 A 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 14 G 17 G 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 17 N 20 S 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 18 G 21 G 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 19 I 22 I 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 38 D 41 D 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 39 F 43 F 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 59 V 63 V 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 60 D 64 D 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 61 V 65 V 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 87 N 91 N 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 88 A 92 A 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 89 G 98 A 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 90 I 99 T 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 137 T 146 T 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 139 S 148 S 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 152 Y 161 Y 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 156 K 165 K 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 182 P 191 P 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 184 F 193 V 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 185 T 194 I 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 187 T 196 T 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4nbu:B 37.8 5 252 2 242 Crystal structure of fabg from bacillus sp 2e-36 150 binding 1,4-dihydronicotinamide adenine dinucleotide 189 M 199 M 24212572 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:B 35.5 7 259 4 252 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 147 active site 18 G 21 G 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:B 35.5 7 259 4 252 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 147 active site 140 S 148 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:B 35.5 7 259 4 252 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 147 active site 153 Y 161 Y 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:B 35.5 7 259 4 252 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 147 binding adenosine-5'-diphosphate 14 G 17 G 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:B 35.5 7 259 4 252 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 147 binding adenosine-5'-diphosphate 17 N 20 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:B 35.5 7 259 4 252 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 147 binding adenosine-5'-diphosphate 38 D 41 D 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:B 35.5 7 259 4 252 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 147 binding adenosine-5'-diphosphate 39 W 42 L 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:B 35.5 7 259 4 252 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 147 binding adenosine-5'-diphosphate 61 I 63 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:B 35.5 7 259 4 252 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 147 binding adenosine-5'-diphosphate 62 D 64 D 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:B 35.5 7 259 4 252 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 147 binding adenosine-5'-diphosphate 63 V 65 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:B 35.5 7 259 4 252 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 147 binding adenosine-5'-diphosphate 91 G 93 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 active site 16 G 21 G 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 active site 138 S 148 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 active site 151 Y 161 Y 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 12 G 17 G 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 15 N 20 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 16 G 21 G 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 17 M 22 I 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 36 D 41 D 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 37 W 42 L 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 37 W 42 L 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 38 A 43 F 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 59 I 63 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 60 D 64 D 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 61 V 65 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 87 N 91 N 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 88 A 92 A 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 89 G 93 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 90 V 94 Y 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 110 V 119 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 136 T 146 T 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 138 S 148 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 151 Y 161 Y 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 155 K 165 K 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 181 P 191 P 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 182 S 192 G 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 183 L 193 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 184 V 194 I 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 186 T 196 T 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 187 N 197 P 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 188 M 198 A 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6vsp:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase mutant q247a 3e-35 146 binding nicotinamide-adenine-dinucleotide 189 T 199 M 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding 15 N 20 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding 17 M 22 I 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding 36 D 41 D 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding 60 D 64 D 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding 61 V 65 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding 87 N 91 N 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding ; binding 138 S 148 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 mutation to Q: Retains 50% of activity with acetoin... 139 V 149 T 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding 140 S 150 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding ; binding ; binding 151 Y 161 Y 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding 155 K 165 K 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding 184 V 194 I 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 binding 186 T 196 T 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 mutation to SEAAGKPLGYGTET: Mimics longer alpha6 helix. Retains 3%... 197..199 RDK 208..210 KSA 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt MBDH_SERMA 35.5 7 259 2 250 Meso-2,3-butanediol dehydrogenase; BDH; meso-2,3-BDH; (R,S)-butane-2,3-diol dehydrogenase; NAD(H)-dependent meso-2,3-BDH; SmBdh; EC 1.1.1.- from Serratia marcescens 4e-35 146 mutation to A: Retains 10% of activity with acetoin... 247 Q 256 T 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 active site 16 G 21 G 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 active site 138 S 148 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 active site 151 Y 161 Y 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding r,3-hydroxybutan-2-one 138 S 148 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding r,3-hydroxybutan-2-one 140 S 150 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding r,3-hydroxybutan-2-one 151 Y 161 Y 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding s,3-hydroxybutan-2-one 138 S 148 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding s,3-hydroxybutan-2-one 151 Y 161 Y 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding s,3-hydroxybutan-2-one 182 S 192 G 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 12 G 17 G 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 15 N 20 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 16 G 21 G 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 17 M 22 I 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 36 D 41 D 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 37 W 42 L 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 37 W 42 L 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 38 A 43 F 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 59 I 63 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 60 D 64 D 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 61 V 65 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 87 N 91 N 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 88 A 92 A 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 89 G 93 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 110 V 119 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 136 T 146 T 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 138 S 148 S 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 151 Y 161 Y 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 155 K 165 K 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 182 S 192 G 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 183 L 193 V 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 184 V 194 I 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 186 T 196 T 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 187 N 197 P 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 188 M 198 A 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6xew:A 35.5 7 259 2 250 Structure of serratia marcescens 2,3-butanediol dehydrogenase 4e-35 146 binding nicotinamide-adenine-dinucleotide 189 T 199 M 33292448 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 active site 16 G 21 G PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 active site 142 S 148 S PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 active site 153 V 158 Q PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 active site 156 Y 161 Y PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 active site 160 K 165 K PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 12 G 17 G PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 14 S 19 G PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 15 S 20 S PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 16 G 21 G PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 17 I 22 I PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 36 A 41 D PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 37 R 42 L PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 38 N 43 F PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 63 V 65 V PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 89 N 91 N PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 90 A 92 A PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 91 G 97 P PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 140 T 146 T PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 142 S 148 S PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 156 Y 161 Y PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 160 K 165 K PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 186 P 191 P PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 188 G 193 V PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 189 T 194 I PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 3tox:A 40.3 6 254 1 252 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021 5e-34 143 binding nadp nicotinamide-adenine-dinucleotide phosphate 191 T 196 T PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt PED_AROAE 38.0 6 252 3 246 (S)-1-Phenylethanol dehydrogenase; EC 1.1.1.311 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) 7e-34 142 binding 17..19 NGI 20..22 SGI 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt PED_AROAE 38.0 6 252 3 246 (S)-1-Phenylethanol dehydrogenase; EC 1.1.1.311 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) 7e-34 142 binding 38 D 41 D 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt PED_AROAE 38.0 6 252 3 246 (S)-1-Phenylethanol dehydrogenase; EC 1.1.1.311 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) 7e-34 142 binding 61..63 CDV 63..65 VDV 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt PED_AROAE 38.0 6 252 3 246 (S)-1-Phenylethanol dehydrogenase; EC 1.1.1.311 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) 7e-34 142 binding 89 N 91 N 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt PED_AROAE 38.0 6 252 3 246 (S)-1-Phenylethanol dehydrogenase; EC 1.1.1.311 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) 7e-34 142 binding 93 Y 94 Y 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt PED_AROAE 38.0 6 252 3 246 (S)-1-Phenylethanol dehydrogenase; EC 1.1.1.311 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) 7e-34 142 binding 158 K 165 K 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt PED_AROAE 38.0 6 252 3 246 (S)-1-Phenylethanol dehydrogenase; EC 1.1.1.311 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) 7e-34 142 binding 184..187 PSLV 191..194 PGVI 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt PED_AROAE 38.0 6 252 3 246 (S)-1-Phenylethanol dehydrogenase; EC 1.1.1.311 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) 7e-34 142 binding 191 T 198 A 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt PED_AROAE 38.0 6 252 3 246 (S)-1-Phenylethanol dehydrogenase; EC 1.1.1.311 from Aromatoleum aromaticum (strain EbN1) (Azoarcus sp. (strain EbN1)) 7e-34 142 modified: Initiator methionine, Removed 1 11479712 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 active site 16 G 21 G 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 active site 139 S 148 S 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 active site 149 Y 158 Q 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 active site 152 Y 161 Y 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 active site 156 K 165 K 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 12 G 17 G 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 15 N 20 S 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 16 G 21 G 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 17 I 22 I 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 36 D 41 D 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 37 L 42 L 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 59 C 63 V 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 60 D 64 D 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 61 V 65 V 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 87 N 91 N 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 139 S 148 S 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 152 Y 161 Y 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 156 K 165 K 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 182 P 191 P 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 183 S 192 G 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 184 L 193 V 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 185 V 194 I 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ewm:B 38.0 6 252 1 244 Crystal structure of the (s)-specific 1-phenylethanol dehydrogenase of the denitrifying bacterium strain ebn1 7e-34 142 binding nicotinamide-adenine-dinucleotide 189 T 198 A 16388583 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 active site 16 G 21 G 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 active site 142 S 148 S 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 active site 155 Y 161 Y 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 active site 159 K 165 K 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 12 G 17 G 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 15 S 20 S 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 16 G 21 G 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 17 I 22 I 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 36 D 41 D 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 37 I 42 L 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 61 A 63 V 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 62 D 64 D 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 63 T 65 V 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 89 N 91 N 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 90 A 92 A 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 140 M 146 T 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 142 S 148 S 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 155 Y 161 Y 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 159 K 165 K 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 185 P 191 P 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 186 A 192 G 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 187 Y 193 V 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 188 I 194 I 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 6ixm:C 32.4 8 253 3 246 Crystal structure of the ketone reductase chkred20 from the genome of chryseobacterium sp. Ca49 complexed with NAD 1e-32 138 binding nicotinamide-adenine-dinucleotide 192 L 198 A 30885322 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 active site 18 G 21 G 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 active site 144 S 148 S 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 active site 157 Y 161 Y 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 active site 161 K 165 K 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 active site 202 S 203 A 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 14 G 17 G 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 17 S 20 S 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 18 G 21 G 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 19 I 22 I 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 38 E 41 D 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 39 L 42 L 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 43 R 46 S 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 63 A 63 V 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 64 D 64 D 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 65 V 65 V 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 91 N 91 N 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 93 G 93 V 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 94 I 94 Y 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 142 T 146 T 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 144 S 148 S 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 157 Y 161 Y 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 161 K 165 K 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 187 P 191 P 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 190 V 194 I 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 192 T 196 T 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 193 N 197 P 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 4fn4:A 34.1 6 254 3 253 Short-chain NAD(h)-dependent dehydrogenase/reductase from sulfolobus acidocaldarius 1e-32 138 binding nicotinamide-adenine-dinucleotide 194 I - 22805786 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 binding 11..35 VITGSSTGLGKSMAIRFATEKAKVV 14..38 VITGAGSGIGRASALRFAREGATVV 11173533 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 mutation E->A,G,K: Heat stable. 96 E 95 R 2495285 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 mutation to N: Heat stable. 108 D 107 N 2495285 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 mutation to A: Heat stable. 112 V 116 C 2495285 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 mutation to K: Heat stable. 133 E 137 A 2495285 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 mutation to I: Heat stable. 183 V 186 C 2495285 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 mutation to Q: Heat stable. 194 P 197 P 2495285 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 mutation to K: Heat stable. 210 E 212 L 2495285 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 mutation to H: Heat stable. 217 Y 219 Q 2495285 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 Q→L: Heat stable. 252 2495285 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 Y→C: Heat stable. 253 2495285 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt DHG_PRIMG 33.6 4 253 1 251 Glucose 1-dehydrogenase; EC 1.1.1.47 from Priestia megaterium (Bacillus megaterium) 2e-32 137 A→G: Heat stable. 258 2495285 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt LVR_LEIAQ 36.5 7 254 10 265 Levodione reductase; (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase; EC 1.1.1.- from Leifsonia aquatica (Corynebacterium aquaticum) 2e-32 137 binding 17..42 LITGGGSGLGRATAVRLAAEGAKLSL 14..39 VITGAGSGIGRASALRFAREGATVVV 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR SwissProt LVR_LEIAQ 36.5 7 254 10 265 Levodione reductase; (6R)-2,2,6-trimethyl-1,4-cyclohexanedione reductase; EC 1.1.1.- from Leifsonia aquatica (Corynebacterium aquaticum) 2e-32 137 mutation E->A,D,N,Q: 26-fold increase in Km and a much... 103 E - 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 active site 15 G 21 G 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 active site 143 S 148 S 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 active site 153 Q 158 Q 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 active site 156 Y 161 Y 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 active site 160 K 165 K 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 11 G 17 G 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 14 S 20 S 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 15 G 21 G 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 16 L 22 I 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 35 D 41 D 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 36 V 42 L 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 62 A - 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 63 D 64 D 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 64 V 65 V 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 90 N 91 N 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 92 G 93 V 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 93 I - 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 141 T 146 T 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 143 S 148 S 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 156 Y 161 Y 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 160 K 165 K 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 186 P 191 P 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 187 G 192 G 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 191 T 196 T 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 192 P 197 P 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1iy8:A 36.5 7 254 1 256 Crystal structure of levodione reductase 2e-32 137 binding nicotinamide-adenine-dinucleotide 193 M 198 A 12621044 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 active site 18 G 21 G PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 active site 145 S 148 S PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 active site 158 Y 161 Y PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 active site 162 K 165 K PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 17 T 20 S PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 18 G 21 G PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 19 L 22 I PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 39 R 42 L PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 65 D 64 D PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 66 V 65 V PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 92 N 91 N PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 93 A 92 A PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 94 G 93 V PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 143 M 146 T PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 145 S 148 S PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 158 Y 161 Y PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 188 P 191 P PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 189 G 192 G PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 191 I 194 I PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 1g6k:A 33.6 4 253 1 251 Crystal structure of glucose dehydrogenase mutant e96a complexed with NAD+ 4e-32 136 binding nicotinamide-adenine-dinucleotide 193 T 196 T PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 active site 133 S 148 S 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 active site 147 Y 161 Y 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 active site 151 K 165 K 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 active site 192 R - 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 16 Q 20 S 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 17 G 21 G 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 18 I 22 I 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 37 D 41 D 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 38 I 42 L 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 58 D 62 Q 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 59 V 63 V 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 81 V 91 N 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 83 G 93 V 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 104 L 119 V 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 147 Y 161 Y 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 151 K 165 K 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 177 P 191 P 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 180 V 194 I 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 182 T 196 T 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding nicotinamide-adenine-dinucleotide 184 S 198 A 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding sulfate ion 144 R 158 Q 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding sulfate ion 188 R 202 W 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding sulfate ion 202 F 211 F 16380372 PfGW456L13_3453 Short-chain dehydrogenase/reductase SDR PDB 2ag5:A 36.5 7 255 3 246 Crystal structure of human dhrs6 7e-32 135 binding sulfate ion 205 R 214 L 16380372