Comparing 14450 FitnessBrowser__Keio:14450 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8skfA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (lattice translocation disorder)
89% identity, 100% coverage: 1:490/490 of query aligns to 8:497/497 of 8skfA
8vr1A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (ctp bound)
89% identity, 100% coverage: 3:490/490 of query aligns to 1:488/488 of 8vr1A
8vr0A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (gmp bound)
89% identity, 100% coverage: 3:490/490 of query aligns to 1:488/488 of 8vr0A
8vqzA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (cmp bound)
89% identity, 100% coverage: 3:490/490 of query aligns to 1:488/488 of 8vqzA
8vqwC Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (coa bound)
89% identity, 100% coverage: 3:490/490 of query aligns to 1:488/488 of 8vqwC
8vj3A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (fad bound)
89% identity, 100% coverage: 3:490/490 of query aligns to 1:488/488 of 8vj3A
8uzoA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (adp bound)
89% identity, 100% coverage: 3:490/490 of query aligns to 1:488/488 of 8uzoA
8uznA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (amp bound)
89% identity, 100% coverage: 3:490/490 of query aligns to 1:488/488 of 8uznA
8uzmA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (NADPH bound)
89% identity, 100% coverage: 3:490/490 of query aligns to 1:488/488 of 8uzmA
8uzkA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (NADP+ bound)
89% identity, 100% coverage: 3:490/490 of query aligns to 1:488/488 of 8uzkA
Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase; BADH; EC 1.2.1.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
77% identity, 100% coverage: 1:490/490 of query aligns to 1:490/490 of Q9HTJ1
4cazA Crystal structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa in complex with nadh
77% identity, 100% coverage: 2:490/490 of query aligns to 1:489/489 of 4cazA
2woxA Betaine aldehyde dehydrogenase from pseudomonas aeruginosa with NAD(p) h-catalytic thiol adduct. (see paper)
77% identity, 100% coverage: 2:490/490 of query aligns to 1:489/489 of 2woxA
2wmeA Crystallographic structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa (see paper)
77% identity, 100% coverage: 2:490/490 of query aligns to 1:489/489 of 2wmeA
6wsbA Crystal structure of a betaine aldehyde dehydrogenase from burkholderia pseudomallei bound to cofactor NAD (see paper)
71% identity, 99% coverage: 7:490/490 of query aligns to 6:488/489 of 6wsbA
P49189 4-trimethylaminobutyraldehyde dehydrogenase; TMABA-DH; TMABALDH; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; Formaldehyde dehydrogenase; Gamma-aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; EC 1.2.1.47; EC 1.2.1.3; EC 1.2.1.46; EC 1.2.1.19 from Homo sapiens (Human) (see 2 papers)
52% identity, 99% coverage: 7:490/490 of query aligns to 10:494/494 of P49189
Sites not aligning to the query:
6vr6D Structure of aldh9a1 complexed with NAD+ in space group p1 (see paper)
52% identity, 99% coverage: 7:490/490 of query aligns to 9:493/493 of 6vr6D
1bpwA Betaine aldehyde dehydrogenase from cod liver (see paper)
52% identity, 98% coverage: 10:490/490 of query aligns to 23:503/503 of 1bpwA
P56533 4-trimethylaminobutyraldehyde dehydrogenase; TMABA-DH; TMABADH; Aldehyde dehydrogenase family 9 member A1; Betaine aldehyde dehydrogenase; BADH; EC 1.2.1.47; EC 1.2.1.3 from Gadus morhua subsp. callarias (Baltic cod) (Gadus callarias) (see paper)
52% identity, 98% coverage: 10:490/490 of query aligns to 23:503/503 of P56533
6vwfA Structure of aldh9a1 complexed with NAD+ in space group c222 (see paper)
47% identity, 99% coverage: 7:490/490 of query aligns to 10:450/450 of 6vwfA
>14450 FitnessBrowser__Keio:14450
MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGREDVDRAVKSAQQGQKIW
ASMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETSTVDIVTGADVLEYYAGLI
PALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEV
TPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTEHPGIAKVSFTGGVASGKKVMAN
SAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMMANFFSSGQVCTNGTRVFVPAKCKA
AFEQKILARVERIRAGDVFDPQTNFGPLVSFPHRDNVLRYIAKGKEEGARVLCGGDVLKG
DGFDNGAWVAPTVFTDCSDDMTIVREEIFGPVMSILTYESEDEVIRRANDTDYGLAAGIV
TADLNRAHRVIHQLEAGICWINTWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQ
VEMAKFQSIF
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory