Comparing 14824 FitnessBrowser__Keio:14824 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
1ordA Crystallographic structure of a plp-dependent ornithine decarboxylase from lactobacillus 30a to 3.1 angstroms resolution (see paper)
56% identity, 97% coverage: 2:712/732 of query aligns to 2:711/730 of 1ordA
1c4kA Ornithine decarboxylase mutant (gly121tyr) (see paper)
56% identity, 97% coverage: 2:712/732 of query aligns to 2:709/728 of 1c4kA
6q6iA Lysine decarboxylase a from pseudomonas aeruginosa
35% identity, 90% coverage: 58:718/732 of query aligns to 92:746/749 of 6q6iA
2vycA Crystal structure of acid induced arginine decarboxylase from e. Coli (see paper)
32% identity, 90% coverage: 58:714/732 of query aligns to 86:752/755 of 2vycA
P28629 Biodegradative arginine decarboxylase; ADC; EC 4.1.1.19 from Escherichia coli (strain K12) (see paper)
32% identity, 90% coverage: 58:714/732 of query aligns to 86:752/755 of P28629
6q7lA Inducible lysine decarboxylase (see paper)
33% identity, 86% coverage: 82:712/732 of query aligns to 103:706/711 of 6q7lA
3n75A X-ray crystal structure of the escherichia coli inducible lysine decarboxylase ldci (see paper)
33% identity, 86% coverage: 82:712/732 of query aligns to 103:706/711 of 3n75A
Sites not aligning to the query:
5xx1G Crystal structure of arginine decarboxylase (adia) from salmonella typhimurium (see paper)
30% identity, 90% coverage: 58:714/732 of query aligns to 87:732/735 of 5xx1G
>14824 FitnessBrowser__Keio:14824
MSKLKIAVSDSCPDCFTTQRECIYINESRNIDVAAIVLSLNDVTCGKLDEIDATGYGIPV
FIATENQERVPAEYLPRISGVFENCESRREFYGRQLETAASHYETQLRPPFFRALVDYVN
QGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEALFRADLCNADVAMGDLLIHEGAPCIAQ
QHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
YLETARNPYGFIGGIDAHCFEESYLRELIAEVAPQRAKEARPFRLAVIQLGTYDGTIYNA
RQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCSPLLLDLNENDPGILVTQSVHKQQAGF
SQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYPLFAALNINAKMHEGVSGRNM
WMDCVVNGINARKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFQFVPGEHWHS
FEGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSIL
FLLTPAEDMAKLQQLVALLVRFEKLLESDAPLAEVLPSIYKQHEERYAGYTLRQLCQEMH
DLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPY
PPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
DAQSTLLKGEKL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory