Comparing 14988 FitnessBrowser__Keio:14988 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2y7iA Structural basis for high arginine specificity in salmonella typhimurium periplasmic binding protein stm4351. (see paper)
53% identity, 93% coverage: 16:241/243 of query aligns to 1:227/228 of 2y7iA
4zv2A An ancestral arginine-binding protein bound to glutamine (see paper)
42% identity, 91% coverage: 22:241/243 of query aligns to 5:223/225 of 4zv2A
4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
42% identity, 91% coverage: 22:241/243 of query aligns to 5:225/226 of 4zv1A
3tqlA Structure of the amino acid abc transporter, periplasmic amino acid- binding protein from coxiella burnetii. (see paper)
45% identity, 91% coverage: 21:241/243 of query aligns to 2:225/225 of 3tqlA
P0AEU0 Histidine-binding periplasmic protein; HBP from Escherichia coli (strain K12) (see 3 papers)
38% identity, 91% coverage: 21:241/243 of query aligns to 26:253/260 of P0AEU0
Sites not aligning to the query:
P02910 Histidine-binding periplasmic protein; HBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
39% identity, 91% coverage: 21:241/243 of query aligns to 26:253/260 of P02910
Sites not aligning to the query:
1hslA Refined 1.89 angstroms structure of the histidine-binding protein complexed with histidine and its relationship with many other active transport(slash)chemosensory receptors (see paper)
39% identity, 91% coverage: 21:241/243 of query aligns to 4:231/238 of 1hslA
P02911 Lysine/arginine/ornithine-binding periplasmic protein; LAO-binding protein from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
34% identity, 99% coverage: 1:241/243 of query aligns to 1:253/260 of P02911
5owfA Structure of a lao-binding protein mutant with glutamine (see paper)
33% identity, 91% coverage: 21:241/243 of query aligns to 1:228/235 of 5owfA
1lstA Three-dimensional structures of the periplasmic lysine-, arginine-, ornithine-binding protein with and without a ligand (see paper)
33% identity, 91% coverage: 21:241/243 of query aligns to 4:231/238 of 1lstA
1lahE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein (see paper)
33% identity, 91% coverage: 21:241/243 of query aligns to 4:231/238 of 1lahE
1lagE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein (see paper)
33% identity, 91% coverage: 21:241/243 of query aligns to 4:231/238 of 1lagE
1lafE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein (see paper)
33% identity, 91% coverage: 21:241/243 of query aligns to 4:231/238 of 1lafE
6svfA Crystal structure of the p235gk mutant of argbp from t. Maritima (see paper)
36% identity, 88% coverage: 29:243/243 of query aligns to 18:229/229 of 6svfA
5otaA Structure of the periplasmic binding protein (pbp) noct from agrobacterium tumefaciens c58 in complex with octopinic acid (see paper)
31% identity, 91% coverage: 21:241/243 of query aligns to 2:248/254 of 5otaA
5ot9A Structure of the periplasmic binding protein (pbp) noct from a.Tumefaciens c58 in complex with histopine. (see paper)
31% identity, 91% coverage: 21:241/243 of query aligns to 2:248/254 of 5ot9A
4powA Structure of the pbp noct in complex with pyronopaline (see paper)
31% identity, 91% coverage: 21:241/243 of query aligns to 2:248/254 of 4powA
5otcA Structure of the periplasmic binding protein (pbp) noct from agrobacterium tumefaciens c58 in complex with noroctopinic acid. (see paper)
31% identity, 91% coverage: 21:241/243 of query aligns to 2:248/256 of 5otcA
5ovzA High resolution structure of the pbp noct in complex with nopaline (see paper)
31% identity, 91% coverage: 21:241/243 of query aligns to 3:249/259 of 5ovzA
5itoA Structure of the periplasmic binding protein m117n-noct from a. Tumefaciens in complex with octopine (see paper)
31% identity, 91% coverage: 21:241/243 of query aligns to 3:249/255 of 5itoA
>14988 FitnessBrowser__Keio:14988
MKKVLIAALIAGFSLSATAAETIRFATEASYPPFESIDANNQIVGFDVDLAQALCKEIDA
TCTFSNQAFDSLIPSLKFRRVEAVMAGMDITPEREKQVLFTTPYYDNSALFVGQQGKYTS
VDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAKLDLQNGRIDGVFGDTAVVTE
WLKDNPKLAAVGDKVTDKDYFGTGLGIAVRQGNTELQQKLNTALEKVKKDGTYETIYNKW
FQK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory