Comparing 14995 FitnessBrowser__Keio:14995 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 15 hits to proteins with known functional sites (download)
3wlxA Crystal structure of low-specificity l-threonine aldolase from escherichia coli
100% identity, 99% coverage: 1:331/333 of query aligns to 1:331/331 of 3wlxA
4rjyA Crystal structure of e. Coli l-threonine aldolase in complex with a non-covalently uncleaved bound l-serine substrate (see paper)
99% identity, 100% coverage: 1:332/333 of query aligns to 1:332/332 of 4rjyA
4lnlA Structure of escherichia coli threonine aldolase in complex with allo- thr (see paper)
99% identity, 100% coverage: 1:332/333 of query aligns to 1:332/332 of 4lnlA
4lnjA Structure of escherichia coli threonine aldolase in unliganded form (see paper)
99% identity, 100% coverage: 1:332/333 of query aligns to 1:332/332 of 4lnjA
4lnmA Structure of escherichia coli threonine aldolase in complex with serine (see paper)
99% identity, 99% coverage: 1:331/333 of query aligns to 1:331/331 of 4lnmA
O07051 L-allo-threonine aldolase; L-allo-TA; L-allo-threonine acetaldehyde-lyase; EC 4.1.2.49 from Aeromonas jandaei (see paper)
53% identity, 99% coverage: 2:331/333 of query aligns to 4:336/338 of O07051
3wgcB Aeromonas jandaei l-allo-threonine aldolase h128y/s292r double mutant (see paper)
53% identity, 99% coverage: 2:331/333 of query aligns to 3:333/333 of 3wgcB
3wgbD Crystal structure of aeromonas jandaei l-allo-threonine aldolase (see paper)
54% identity, 97% coverage: 2:325/333 of query aligns to 2:319/324 of 3wgbD
1jg8D Crystal structure of threonine aldolase (low-specificity)
49% identity, 97% coverage: 1:322/333 of query aligns to 2:331/344 of 1jg8D
1lw5B X-ray structure of l-threonine aldolase (low-specificity) in complex with glycine (see paper)
49% identity, 97% coverage: 1:322/333 of query aligns to 1:330/343 of 1lw5B
1lw4B X-ray structure of l-threonine aldolase (low-specificity) in complex with l-allo-threonine (see paper)
49% identity, 97% coverage: 1:322/333 of query aligns to 1:330/343 of 1lw4B
Q8RXU4 Low-specificity L-threonine aldolase 1; Threonine aldolase 1; EC 4.1.2.48 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
40% identity, 95% coverage: 2:316/333 of query aligns to 6:334/358 of Q8RXU4
5vyeB Crystal structure of l-threonine aldolase from pseudomonas putida
25% identity, 92% coverage: 27:331/333 of query aligns to 30:342/344 of 5vyeB
O50584 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Pseudomonas sp. (strain NCIMB 10558) (see paper)
29% identity, 47% coverage: 30:185/333 of query aligns to 35:193/346 of O50584
Sites not aligning to the query:
1v72A Crystal structure of phenylserine aldolase from pseudomonas putida
24% identity, 55% coverage: 2:185/333 of query aligns to 5:193/345 of 1v72A
Sites not aligning to the query:
>14995 FitnessBrowser__Keio:14995
MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQ
ANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKI
KPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRERNLALHVDGARIFNAVVAYGCE
LKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGIY
ALKNNVARLQEDHDNAAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVL
INASPIVRLVTHLDVSREQLAEVAAHWRAFLAR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory