Comparing 16018 FitnessBrowser__Keio:16018 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 16 hits to proteins with known functional sites (download)
5abpA Substrate specificity and affinity of a protein modulated by bound water molecules (see paper)
100% identity, 93% coverage: 25:329/329 of query aligns to 1:305/305 of 5abpA
1abfA Substrate specificity and affinity of a protein modulated by bound water molecules (see paper)
100% identity, 93% coverage: 25:329/329 of query aligns to 1:305/305 of 1abfA
1abeA Novel stereospecificity of the l-arabinose-binding protein (see paper)
100% identity, 93% coverage: 25:329/329 of query aligns to 1:305/305 of 1abeA
4kzkA The structure of the periplasmic l-arabinose binding protein from burkholderia thailandensis
46% identity, 91% coverage: 26:326/329 of query aligns to 1:301/301 of 4kzkA
5ibqA Crystal structure of an abc solute binding protein from rhizobium etli cfn 42 (rhe_pf00037,target efi-511357) in complex with alpha-d-apiose
22% identity, 88% coverage: 28:316/329 of query aligns to 5:277/287 of 5ibqA
4ry0A Crystal structure of ribose transporter solute binding protein rhe_pf00037 from rhizobium etli cfn 42, target efi-511357, in complex with d-ribose
22% identity, 88% coverage: 28:316/329 of query aligns to 5:277/287 of 4ry0A
P23905 D-galactose/methyl-galactoside binding periplasmic protein MglB; D-galactose-binding periplasmic protein; GBP; D-galactose/D-glucose-binding protein; GGBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
24% identity, 84% coverage: 1:276/329 of query aligns to 1:278/332 of P23905
Sites not aligning to the query:
5kwsA Crystal structure of galactose binding protein from yersinia pestis in the complex with beta d glucose
25% identity, 60% coverage: 65:262/329 of query aligns to 44:240/307 of 5kwsA
Sites not aligning to the query:
2fn8A Thermotoga maritima ribose binding protein ribose bound form (see paper)
23% identity, 88% coverage: 27:316/329 of query aligns to 3:282/292 of 2fn8A
P0AEE5 D-galactose/methyl-galactoside binding periplasmic protein MglB; D-galactose-binding periplasmic protein; GBP; D-galactose/D-glucose-binding protein; GGBP from Escherichia coli (strain K12) (see 4 papers)
23% identity, 84% coverage: 1:276/329 of query aligns to 1:278/332 of P0AEE5
Sites not aligning to the query:
8fxtA Escherichia coli periplasmic glucose-binding protein glucose complex: acrylodan conjugate attached at w183c (see paper)
25% identity, 64% coverage: 65:276/329 of query aligns to 43:254/305 of 8fxtA
Sites not aligning to the query:
2ioyA Crystal structure of thermoanaerobacter tengcongensis ribose binding protein (see paper)
23% identity, 88% coverage: 28:318/329 of query aligns to 3:274/274 of 2ioyA
2qw1A Glucose/galactose binding protein bound to 3-o-methyl d-glucose (see paper)
25% identity, 64% coverage: 65:276/329 of query aligns to 43:254/305 of 2qw1A
2gbpA Sugar and signal-transducer binding sites of the escherichia coli galactose chemoreceptor protein (see paper)
25% identity, 64% coverage: 65:276/329 of query aligns to 44:255/309 of 2gbpA
Sites not aligning to the query:
3ga5A X-ray structure of glucose/galactose receptor from salmonella typhimurium in complex with (2r)-glyceryl-beta-d-galactopyranoside (see paper)
25% identity, 64% coverage: 65:276/329 of query aligns to 42:253/305 of 3ga5A
Sites not aligning to the query:
1gcaA The 1.7 angstroms refined x-ray structure of the periplasmic glucose(slash)galactose receptor from salmonella typhimurium (see paper)
25% identity, 64% coverage: 65:276/329 of query aligns to 44:255/309 of 1gcaA
Sites not aligning to the query:
>16018 FitnessBrowser__Keio:16018
MHKFTKALAAIGLAAVMSQSAMAENLKLGFLVKQPEEPWFQTEWKFADKAGKDLGFEVIK
IAVPDGEKTLNAIDSLAASGAKGFVICTPDPKLGSAIVAKARGYDMKVIAVDDQFVNAKG
KPMDTVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAVMAITANELDTARRRTTGSMD
ALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPEVKHWLIVGMNDSTVLGGVRATE
GQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLLPSPDVHGYKSSEMLYNWVAKDVEP
PKFTEVTDVVLITRDNFKEELEKKGLGGK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory