Comparing 16329 b2221 acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (NCBI) to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 11 hits to proteins with known functional sites (download)
1k6dB Crystal structure of acetate coa-transferase alpha subunit (see paper)
100% identity, 100% coverage: 1:219/220 of query aligns to 1:219/219 of 1k6dB
1o9lA Succinate:coenzyme-a transferase (pig heart)
36% identity, 98% coverage: 3:218/220 of query aligns to 1:235/468 of 1o9lA
Q29551 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; SCOT; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; Succinate-coenzyme A transferase; Succinyl-CoA:3-oxoacid CoA transferase; EC 2.8.3.5 from Sus scrofa (Pig) (see 3 papers)
36% identity, 92% coverage: 17:218/220 of query aligns to 55:274/520 of Q29551
Sites not aligning to the query:
3oxoE Succinyl-coa:3-ketoacid coa transferase from pig heart covalently bound to coa (see paper)
36% identity, 98% coverage: 3:218/220 of query aligns to 1:235/462 of 3oxoE
Sites not aligning to the query:
3k6mC Dynamic domains of succinyl-coa:3-ketoacid-coenzyme a transferase from pig heart. (see paper)
36% identity, 98% coverage: 3:218/220 of query aligns to 1:235/466 of 3k6mC
Sites not aligning to the query:
8i3yD Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
34% identity, 99% coverage: 4:220/220 of query aligns to 4:238/471 of 8i3yD
8i3yA Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
34% identity, 99% coverage: 4:220/220 of query aligns to 4:238/459 of 8i3yA
Sites not aligning to the query:
8i40A Crystal structure of asct from trypanosoma brucei in complex with coa.
34% identity, 99% coverage: 4:220/220 of query aligns to 4:238/467 of 8i40A
Sites not aligning to the query:
2ahvA Crystal structure of acyl-coa transferase from e. Coli o157:h7 (ydif)- thioester complex with coa- 1 (see paper)
24% identity, 99% coverage: 2:219/220 of query aligns to 9:253/512 of 2ahvA
Sites not aligning to the query:
Q0S7P9 Cholesterol ring-cleaving hydrolase IpdA subunit; (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase alpha subunit; COCHEA-CoA hydrolase alpha subunit; EC 4.1.99.- from Rhodococcus jostii (strain RHA1) (see paper)
29% identity, 90% coverage: 2:198/220 of query aligns to 5:214/296 of Q0S7P9
6co9A Crystal structure of rhodococcus jostii rha1 ipdab cochea-coa complex (see paper)
29% identity, 90% coverage: 2:198/220 of query aligns to 4:213/295 of 6co9A
>16329 b2221 acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (NCBI)
MKTKLMTLQDATGFFRDGMTIMVGGFMGIGTPSRLVEALLESGVRDLTLIANDTAFVDTG
IGPLIVNGRVRKVIASHIGTNPETGRRMISGEMDVVLVPQGTLIEQIRCGGAGLGGFLTP
TGVGTVVEEGKQTLTLDGKTWLLERPLRADLALIRAHRCDTLGNLTYQLSARNFNPLIAL
AADITLVEPDELVETGELQPDHIVTPGAVIDHIIVSQESK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory