Comparing 16899 FitnessBrowser__Keio:16899 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P0A6C5 Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS; NAGS; EC 2.3.1.1 from Escherichia coli (strain K12) (see paper)
100% identity, 100% coverage: 1:443/443 of query aligns to 1:443/443 of P0A6C5
4i49A Structure of ngnags bound with bisubstrate analog coa-NAG (see paper)
40% identity, 98% coverage: 9:442/443 of query aligns to 3:422/424 of 4i49A
3d2mA Crystal structure of n-acetylglutamate synthase from neisseria gonorrhoeae complexed with coenzyme a and l-glutamate (see paper)
40% identity, 98% coverage: 9:442/443 of query aligns to 3:422/424 of 3d2mA
3b8gA Crysta structure of n-acetylglutamate synthase from neisseria gonorrhoeae complexed with coenzyme a and n-acetyl-glutamate (see paper)
40% identity, 98% coverage: 9:442/443 of query aligns to 3:422/424 of 3b8gA
2r8vA Native structure of n-acetylglutamate synthase from neisseria gonorrhoeae (see paper)
40% identity, 98% coverage: 9:442/443 of query aligns to 3:422/424 of 2r8vA
3d2pA Crystal structure of n-acetylglutamate synthase from neisseria gonorrhoeae complexed with coenzyme a and l-arginine (see paper)
40% identity, 98% coverage: 9:442/443 of query aligns to 3:422/424 of 3d2pA
2btyA Acetylglutamate kinase from thermotoga maritima complexed with its inhibitor arginine (see paper)
32% identity, 62% coverage: 16:290/443 of query aligns to 12:277/282 of 2btyA
Q9X2A4 Acetylglutamate kinase; N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; NAGK; EC 2.7.2.8 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
32% identity, 62% coverage: 16:290/443 of query aligns to 12:277/282 of Q9X2A4
2v5hB Controlling the storage of nitrogen as arginine: the complex of pii and acetylglutamate kinase from synechococcus elongatus pcc 7942 (see paper)
30% identity, 63% coverage: 13:291/443 of query aligns to 10:282/289 of 2v5hB
2bufA Arginine feed-back inhibitable acetylglutamate kinase (see paper)
28% identity, 63% coverage: 13:290/443 of query aligns to 14:286/292 of 2bufA
2bufC Arginine feed-back inhibitable acetylglutamate kinase (see paper)
27% identity, 63% coverage: 13:290/443 of query aligns to 14:294/298 of 2bufC
Q9HTN2 Acetylglutamate kinase; N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; NAGK; EC 2.7.2.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
27% identity, 63% coverage: 13:290/443 of query aligns to 15:295/301 of Q9HTN2
Sites not aligning to the query:
2rd5B Structural basis for the regulation of n-acetylglutamate kinase by pii in arabidopsis thaliana (see paper)
28% identity, 63% coverage: 10:290/443 of query aligns to 6:281/283 of 2rd5B
4usjB N-acetylglutamate kinase from arabidopsis thaliana in complex with pii from chlamydomonas reinhardtii (see paper)
28% identity, 63% coverage: 10:290/443 of query aligns to 4:279/281 of 4usjB
Q9SCL7 Acetylglutamate kinase, chloroplastic; N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AtNAGK; EC 2.7.2.8 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
28% identity, 63% coverage: 10:290/443 of query aligns to 70:345/347 of Q9SCL7
Sites not aligning to the query:
2bufK Arginine feed-back inhibitable acetylglutamate kinase (see paper)
27% identity, 63% coverage: 13:290/443 of query aligns to 14:271/273 of 2bufK
4ab7H Crystal structure of a tetrameric acetylglutamate kinase from saccharomyces cerevisiae complexed with its substrate n- acetylglutamate (see paper)
22% identity, 65% coverage: 19:307/443 of query aligns to 10:298/422 of 4ab7H
3zzhC Crystal structure of the amino acid kinase domain from saccharomyces cerevisiae acetylglutamate kinase in complex with its feed- back inhibitor l-arginine (see paper)
22% identity, 61% coverage: 19:290/443 of query aligns to 28:286/288 of 3zzhC
Sites not aligning to the query:
3wwmA Crystal structure of lysz from thermus thermophilus with adp (see paper)
24% identity, 54% coverage: 28:265/443 of query aligns to 2:246/269 of 3wwmA
O50147 [LysW]-aminoadipate kinase; EC 2.7.2.17 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
24% identity, 54% coverage: 28:265/443 of query aligns to 2:246/269 of O50147
>16899 FitnessBrowser__Keio:16899
MVKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSSIVNDIGLLHSLGIRLV
VVYGARPQIDANLAAHHHEPLYHKNIRVTDAKTLELVKQAAGTLQLDITARLSMSLNNTP
LQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEDAIHRQLDSGAIVLMGPVAVSV
TGESFNLTSEEIATQLAIKLKAEKMIGFCSSQGVTNDDGDIVSELFPNEAQARVEAQEEK
GDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGALLQELFSRDGIGTQIVMESAEQIRR
ATINDIGGILELIRPLEQQGILVRRSREQLEMEIDKFTIIQRDNTTIACAALYPFPEEKI
GEMACVAVHPDYRSSSRGEVLLERIAAQAKQSGLSKLFVLTTRSIHWFQERGFTPVDIDL
LPESKKQLYNYQRKSKVLMADLG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory