Comparing 17628 FitnessBrowser__Keio:17628 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see paper)
45% identity, 100% coverage: 1:511/513 of query aligns to 1:501/501 of P04983
1g6hA Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
30% identity, 48% coverage: 4:250/513 of query aligns to 4:254/254 of 1g6hA
1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter (see paper)
30% identity, 48% coverage: 4:247/513 of query aligns to 4:251/253 of 1g9xB
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
31% identity, 42% coverage: 4:221/513 of query aligns to 1:220/343 of P30750
Sites not aligning to the query:
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
30% identity, 43% coverage: 3:221/513 of query aligns to 1:221/344 of 6cvlD
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
30% identity, 43% coverage: 3:221/513 of query aligns to 1:221/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
30% identity, 43% coverage: 3:221/513 of query aligns to 1:221/344 of 3tuiC
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
26% identity, 42% coverage: 4:219/513 of query aligns to 2:213/241 of 4u00A
4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
28% identity, 42% coverage: 4:218/513 of query aligns to 1:212/240 of 4ymuJ
P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 3 papers)
30% identity, 42% coverage: 4:219/513 of query aligns to 17:225/378 of P69874
Sites not aligning to the query:
3c4jA Abc protein artp in complex with atp-gamma-s
27% identity, 42% coverage: 4:221/513 of query aligns to 3:216/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
27% identity, 42% coverage: 4:221/513 of query aligns to 3:216/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
27% identity, 42% coverage: 4:221/513 of query aligns to 3:216/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
27% identity, 42% coverage: 4:221/513 of query aligns to 3:216/242 of 2oljA
1ji0A Crystal structure analysis of the abc transporter from thermotoga maritima
27% identity, 45% coverage: 4:235/513 of query aligns to 6:232/240 of 1ji0A
6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter (see paper)
27% identity, 42% coverage: 5:222/513 of query aligns to 3:216/235 of 6mhzA
6b8bA E. Coli lptb in complex with adp and a novobiocin derivative (see paper)
27% identity, 42% coverage: 5:222/513 of query aligns to 3:216/233 of 6b8bA
6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide (see paper)
27% identity, 42% coverage: 5:222/513 of query aligns to 3:216/238 of 6s8nB
6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp (see paper)
27% identity, 42% coverage: 5:222/513 of query aligns to 3:216/238 of 6s8gA
6b89A E. Coli lptb in complex with adp and novobiocin (see paper)
27% identity, 42% coverage: 5:222/513 of query aligns to 3:216/234 of 6b89A
>17628 FitnessBrowser__Keio:17628
MPYLLEMKNITKTFGSVKAIDNVCLRLNAGEIVSLCGENGSGKSTLMKVLCGIYPHGSYE
GEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENIFLGNEITHNGIMDYDLMT
LRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQVRLLILDEPTASLTEQETSI
LLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDGQHIGTRDAAGMSEDDIITMMVG
RELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKRVNDVSFSLKRGEILGIAGLVGAGR
TETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQAIAQGIAMVPEDRKRDGIVPVMAVGKN
ITLAALNKFTGGISQLDDAAEQKCILESIQQLKVKTSSPDLAIGRLSGGNQQKAILARCL
LLNPRILILDEPTRGIDIGAKYEIYKLINQLVQQGIAVIVISSELPEVLGLSDRVLVMHE
GKLKANLINHNLTQEQVMEAALRSEHHVEKQSV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory