Comparing 17717 FitnessBrowser__Keio:17717 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P31434 Alpha-xylosidase; EC 3.2.1.177 from Escherichia coli (strain K12) (see 2 papers)
100% identity, 100% coverage: 1:772/772 of query aligns to 1:772/772 of P31434
2f2hA Structure of the yici thiosugar michaelis complex (see paper)
100% identity, 100% coverage: 1:772/772 of query aligns to 1:772/773 of 2f2hA
1xskA Structure of a family 31 alpha glycosidase glycosyl-enzyme intermediate (see paper)
100% identity, 100% coverage: 1:772/772 of query aligns to 1:772/773 of 1xskA
5hxmA Cycloalternan-forming enzyme from listeria monocytogenes in complex with panose (see paper)
28% identity, 76% coverage: 93:675/772 of query aligns to 176:805/1060 of 5hxmA
Sites not aligning to the query:
4kwuA 1.9 angstrom resolution crystal structure of uncharacterized protein lmo2446 from listeria monocytogenes egd-e in complex with alpha-d- glucose, beta-d-glucose, magnesium and calcium
28% identity, 76% coverage: 93:675/772 of query aligns to 175:804/1059 of 4kwuA
Sites not aligning to the query:
6jr7A Flavobacterium johnsoniae gh31 dextranase, fjdex31a, complexed with glucose (see paper)
27% identity, 75% coverage: 92:669/772 of query aligns to 67:662/812 of 6jr7A
4ba0A Crystal structure of agd31b, alpha-transglucosylase, complexed with 5f-alpha-glcf (see paper)
25% identity, 72% coverage: 90:641/772 of query aligns to 56:607/781 of 4ba0A
B3PEE6 Oligosaccharide 4-alpha-D-glucosyltransferase; Alpha-glucosidase 31B; CJAgd31B; EC 2.4.1.161 from Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) (see paper)
25% identity, 72% coverage: 90:641/772 of query aligns to 90:643/816 of B3PEE6
7p4dAAA Oligosaccharide 4-alpha-D-glucosyltransferase (see paper)
26% identity, 72% coverage: 90:641/772 of query aligns to 56:606/780 of 7p4dAAA
Sites not aligning to the query:
7p4cAAA Oligosaccharide 4-alpha-D-glucosyltransferase (see paper)
26% identity, 72% coverage: 90:641/772 of query aligns to 56:606/780 of 7p4cAAA
Sites not aligning to the query:
5npeA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with beta cyclophellitol aziridine probe ky358 (see paper)
26% identity, 72% coverage: 90:641/772 of query aligns to 56:606/780 of 5npeA
Sites not aligning to the query:
5npbA Crystal structure of cjagd31b (alpha-transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol cyclosulfate probe me647 (see paper)
26% identity, 72% coverage: 90:641/772 of query aligns to 56:606/780 of 5npbA
Sites not aligning to the query:
4b9zA Crystal structure of agd31b, alpha-transglucosylase, complexed with acarbose (see paper)
26% identity, 72% coverage: 90:641/772 of query aligns to 56:606/780 of 4b9zA
Sites not aligning to the query:
4b9yA Crystal structure of apo agd31b, alpha-transglucosylase in glycoside hydrolase family 31 (see paper)
26% identity, 72% coverage: 90:641/772 of query aligns to 56:606/780 of 4b9yA
Sites not aligning to the query:
5npdA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with alpha cyclophellitol aziridine probe cf021 (see paper)
25% identity, 72% coverage: 90:641/772 of query aligns to 56:606/780 of 5npdA
Sites not aligning to the query:
5npcA Crystal structure of d412n nucleophile mutant cjagd31b (alpha- transglucosylase from glycoside hydrolase family 31) in complex with unreacted alpha cyclophellitol cyclosulfate probe me647 (see paper)
25% identity, 72% coverage: 90:641/772 of query aligns to 56:606/780 of 5npcA
Sites not aligning to the query:
5i24A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf021 (see paper)
25% identity, 72% coverage: 90:641/772 of query aligns to 56:605/779 of 5i24A
5i23A Crystal structure of agd31b, alpha-transglucosylase in glycoside hydrolase family 31, in complex with cyclophellitol aziridine probe cf022 (see paper)
25% identity, 72% coverage: 90:641/772 of query aligns to 56:605/779 of 5i23A
5zn7A Crystal structure of gh31 alpha-xylosidase from a soil metagenome complexed with xylose
25% identity, 75% coverage: 90:665/772 of query aligns to 53:667/680 of 5zn7A
5aegB A bacterial protein structure in glycoside hydrolase family 31. (see paper)
25% identity, 66% coverage: 140:646/772 of query aligns to 100:639/670 of 5aegB
>17717 FitnessBrowser__Keio:17717
MKISDGNWLIQPGLNLIHPLQVFEVEQQDNEMVVYAAPRDVRERTWQLDTPLFTLRFFSP
QEGIVGVRIEHFQGALNNGPHYPLNILQDVKVTIENTERYAEFKSGNLSARVSKGEFWSL
DFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGETVYGLGERFTALVRNGQTVE
TWNRDGGTSTEQAYKNIPFYMTNRGYGVLVNHPQCVSFEVGSEKVSKVQFSVESEYLEYF
VIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTSFTTNYDEATVNSFIDGMAERNLPL
HVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRRLKAKGLKICVWINPYIGQKSPVFKEL
QEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNPDACKWYADKLKGLVAMGVDCFKTDFGER
IPTDVQWFDGSDPQKMHNHYAYIYNELVWNVLKDTVGEEEAVLFARSASVGAQKFPVHWG
GDCYANYESMAESLRGGLSIGLSGFGFWSHDIGGFENTAPAHVYKRWCAFGLLSSHSRLH
GSKSYRVPWAYDDESCDVVRFFTQLKCRMMPYLYREAARANARGTPMMRAMMMEFPDDPA
CDYLDRQYMLGDNVMVAPVFTEAGDVQFYLPEGRWTHLWHNDELDGSRWHKQQHGFLSLP
VYVRDNTLLALGNNDQRPDYVWHEGTAFHLFNLQDGHEAVCEVPAADGSVIFTLKAARTG
NTITVTGAGEAKNWTLCLRNVVKVNGLQDGSQAESEQGLVVKPQGNALTITL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory