Comparing 18042 FitnessBrowser__Keio:18042 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3cv1A Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design (see paper)
100% identity, 99% coverage: 5:533/533 of query aligns to 1:529/529 of 3cv1A
3cuzA Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design (see paper)
100% identity, 99% coverage: 5:533/533 of query aligns to 1:529/529 of 3cuzA
3cv2A Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design (see paper)
100% identity, 98% coverage: 10:533/533 of query aligns to 1:524/524 of 3cv2A
3cuxA Atomic resolution structures of escherichia coli and bacillis anthracis malate synthase a: comparison with isoform g and implications for structure based drug design (see paper)
53% identity, 96% coverage: 23:532/533 of query aligns to 12:501/501 of 3cuxA
P30952 Malate synthase 1; EC 2.3.3.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
46% identity, 97% coverage: 8:525/533 of query aligns to 15:534/554 of P30952
Sites not aligning to the query:
5cahA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 6h-thieno[2,3-b]pyrrole-5-carboxylic acid (see paper)
23% identity, 69% coverage: 96:464/533 of query aligns to 245:629/706 of 5cahA
1n8iA Biochemical and structural studies of malate synthase from mycobacterium tuberculosis (see paper)
23% identity, 69% coverage: 96:464/533 of query aligns to 243:628/701 of 1n8iA
6dljA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-nitro-phenyldiketoacid (see paper)
23% identity, 69% coverage: 96:464/533 of query aligns to 244:630/704 of 6dljA
Sites not aligning to the query:
6dnpA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-f-3-methyl-6-f-phenyldiketoacid (see paper)
23% identity, 69% coverage: 96:464/533 of query aligns to 249:635/712 of 6dnpA
6c8pA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-f-phenyldiketoacid (see paper)
22% identity, 69% coverage: 96:464/533 of query aligns to 249:639/716 of 6c8pA
6ba7A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-cl-4-oh-phenyldiketoacid (see paper)
23% identity, 69% coverage: 96:464/533 of query aligns to 247:635/709 of 6ba7A
Sites not aligning to the query:
3sadA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 4-(2-mehtylphenyl)-2,4-dioxobutanoic acid inhibitor (see paper)
22% identity, 69% coverage: 96:464/533 of query aligns to 246:634/709 of 3sadA
5cc3A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 6-bromo-1h-indole-2-carboxylic acid
22% identity, 69% coverage: 96:464/533 of query aligns to 249:638/715 of 5cc3A
Sites not aligning to the query:
5cjmA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 4h-thieno[3,2-b]pyrrole-5-carboxylic acid (see paper)
23% identity, 69% coverage: 96:464/533 of query aligns to 249:634/711 of 5cjmA
Sites not aligning to the query:
5driA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-hydroxy-4-(1h-indol-5-yl)-4-oxobut-2-enoic acid inhibitor (see paper)
22% identity, 69% coverage: 96:464/533 of query aligns to 246:635/708 of 5driA
5cc6A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 1h-indole-5-carboxylic acid
23% identity, 69% coverage: 96:464/533 of query aligns to 243:628/701 of 5cc6A
Sites not aligning to the query:
5cc7A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 1h-indole-6-carboxylic acid
23% identity, 69% coverage: 96:464/533 of query aligns to 246:631/704 of 5cc7A
Sites not aligning to the query:
3sb0A Crystal structure of mycobacterium tuberculosis malate synthase in complex with 4-(2-chloro-6-fluoro-3-methylphenyl)-2,4-dioxobutanoic acid inhibitor (see paper)
23% identity, 69% coverage: 96:464/533 of query aligns to 245:631/708 of 3sb0A
Sites not aligning to the query:
3s9iA Crystal structure of mycobacterium tuberculosis malate synthase in complex with 2-4-dioxo-4-phenylbutanoic acid inhibitor (see paper)
23% identity, 69% coverage: 96:464/533 of query aligns to 249:638/714 of 3s9iA
6c7bA Crystal structure of mycobacterium tuberculosis malate synthase in complex with methoxynaphthyldiketoacid (see paper)
23% identity, 69% coverage: 96:464/533 of query aligns to 249:635/710 of 6c7bA
>18042 FitnessBrowser__Keio:18042
MTEQATTTDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQQQDIDN
GTLPDFISETASIRDADWKIRGIPADLEDRRVEITGPVERKMVINALNANVKVFMADFED
SLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNPAVLICRVRGLHLPEKHVTWR
GEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAEDRFNLPR
GTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRVLPDRQA
VTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFIPSKDEEHNNQVLNKVKADKSLEANNG
HDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMREQDAPITADQLLAPCDGERTEEGMRA
NIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKTLSNGKPVTKALFR
QMLGEEMKVIASELGEERFSQGRFDDAARLMEQITTSDELIDFLTLPGYRLLA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory