Comparing 199237 FitnessBrowser__MR1:199237 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
Q9KVT3 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
53% identity, 97% coverage: 8:284/287 of query aligns to 5:275/278 of Q9KVT3
3pgjA 2.49 angstrom resolution crystal structure of shikimate 5- dehydrogenase (aroe) from vibrio cholerae o1 biovar eltor str. N16961 in complex with shikimate
53% identity, 97% coverage: 8:284/287 of query aligns to 1:271/272 of 3pgjA
3sefA 2.4 angstrom resolution crystal structure of shikimate 5-dehydrogenase (aroe) from vibrio cholerae o1 biovar eltor str. N16961 in complex with shikimate and NADPH
52% identity, 97% coverage: 8:284/287 of query aligns to 1:267/268 of 3sefA
1nytA Shikimate dehydrogenase aroe complexed with NADP+ (see paper)
51% identity, 96% coverage: 8:283/287 of query aligns to 1:270/271 of 1nytA
P15770 Shikimate dehydrogenase (NADP(+)); SD; SDH; EC 1.1.1.25 from Escherichia coli (strain K12) (see paper)
51% identity, 96% coverage: 8:283/287 of query aligns to 1:270/272 of P15770
3sefC 2.4 angstrom resolution crystal structure of shikimate 5-dehydrogenase (aroe) from vibrio cholerae o1 biovar eltor str. N16961 in complex with shikimate and NADPH
47% identity, 97% coverage: 8:284/287 of query aligns to 1:244/244 of 3sefC
P43876 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
44% identity, 96% coverage: 8:283/287 of query aligns to 1:271/272 of P43876
1p77A Crystal structure of shikimate dehydrogenase (aroe) from haemophilus influenzae (see paper)
44% identity, 96% coverage: 8:283/287 of query aligns to 1:264/265 of 1p77A
Q5HNV1 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Staphylococcus epidermidis (strain ATCC 35984 / RP62A) (see paper)
34% identity, 96% coverage: 10:284/287 of query aligns to 2:266/269 of Q5HNV1
3dooA Crystal structure of shikimate dehydrogenase from staphylococcus epidermidis complexed with shikimate (see paper)
33% identity, 96% coverage: 10:284/287 of query aligns to 2:257/258 of 3dooA
3phiA Shikimate 5-dehydrogenase (aroe) from helicobacter pylori in complex with shikimate and NADPH
35% identity, 94% coverage: 11:280/287 of query aligns to 6:257/259 of 3phiA
P56119 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
35% identity, 94% coverage: 11:280/287 of query aligns to 6:260/263 of P56119
2hk9A Crystal structure of shikimate dehydrogenase from aquifex aeolicus in complex with shikimate and NADP+ at 2.2 angstrom resolution (see paper)
32% identity, 94% coverage: 11:281/287 of query aligns to 9:266/269 of 2hk9A
2hk9B Crystal structure of shikimate dehydrogenase from aquifex aeolicus in complex with shikimate and NADP+ at 2.2 angstrom resolution (see paper)
32% identity, 94% coverage: 11:281/287 of query aligns to 9:266/267 of 2hk9B
4fosA Crystal structure of shikimate dehydrogenase (aroe) q237a mutant from helicobacter pylori in complex with shikimate
34% identity, 94% coverage: 11:280/287 of query aligns to 6:260/263 of 4fosA
O67049 Shikimate dehydrogenase (NADP(+)); SD; SDH; EC 1.1.1.25 from Aquifex aeolicus (strain VF5) (see paper)
31% identity, 94% coverage: 11:281/287 of query aligns to 9:266/269 of O67049
3phjA Shikimate 5-dehydrogenase (aroe) from helicobacter pylori in complex with 3-dehydroshikimate
34% identity, 94% coverage: 11:280/287 of query aligns to 6:252/255 of 3phjA
Q58484 Shikimate dehydrogenase (NADP(+)); SDH; EC 1.1.1.25 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
31% identity, 94% coverage: 13:283/287 of query aligns to 11:280/282 of Q58484
1nvtB Crystal structure of shikimate dehydrogenase (aroe or mj1084) in complex with NADP+ (see paper)
31% identity, 94% coverage: 13:283/287 of query aligns to 16:285/287 of 1nvtB
1nvtA Crystal structure of shikimate dehydrogenase (aroe or mj1084) in complex with NADP+ (see paper)
31% identity, 94% coverage: 13:283/287 of query aligns to 16:285/287 of 1nvtA
>199237 FitnessBrowser__MR1:199237
MTVTSPIVDRYAVFGHPIGHSKSPFIHGQFAALTQESLTYEAILAPIDGFEASLKSFFSS
GGKGANVTVPFKEQAFALCDSLSAEAALAGAVNTLSLLADGSIRGDNTDGLGLVADLISH
LGSLQHKRVLLVGAGGAARGCILPLLNAGVGQLVITNRTQTKAKDLVDIFSQLEEGIYKD
KLQALSMSELTGEFELVINSTSASLAGELPPLPQSIIGSTTVCYDMMYGAMPTAFNQWAL
QQGAAKVIDGLGMLVGQAAKSFALWRTVEPDTAVVLKLLREKLQLDI
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory