Comparing 200276 FitnessBrowser__MR1:200276 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
7kb1C Complex of o-acety-l-homoserine aminocarboxypropyltransferase (mety) from thermotoga maritima and a key reaction intermediate (see paper)
57% identity, 98% coverage: 7:428/430 of query aligns to 11:426/428 of 7kb1C
7kb1A Complex of o-acety-l-homoserine aminocarboxypropyltransferase (mety) from thermotoga maritima and a key reaction intermediate (see paper)
57% identity, 98% coverage: 7:428/430 of query aligns to 11:426/428 of 7kb1A
2ctzA Crystal structure of o-acetyl homoserine sulfhydrylase from thermus thermophilus hb8
52% identity, 99% coverage: 1:425/430 of query aligns to 1:420/421 of 2ctzA
Q5SK88 O-acetyl-L-homoserine sulfhydrylase 1; OAH-sulfhydrylase 1; EC 2.5.1.- from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
52% identity, 99% coverage: 1:425/430 of query aligns to 1:420/421 of Q5SK88
O13326 Homocysteine synthase; O-acetylhomoserine sulfhydrylase; OAH SHL; OAH sulfhydrylase; EC 2.5.1.49 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
54% identity, 99% coverage: 3:428/430 of query aligns to 8:429/429 of O13326
8erjB Crystal structure of fub7 in complex with e-2-aminocrotonate (see paper)
52% identity, 100% coverage: 1:428/430 of query aligns to 3:426/428 of 8erjB
8erjA Crystal structure of fub7 in complex with e-2-aminocrotonate (see paper)
52% identity, 100% coverage: 1:428/430 of query aligns to 3:426/428 of 8erjA
8erbK Crystal structure of fub7 in complex with vinylglycine ketimine (see paper)
52% identity, 100% coverage: 1:428/430 of query aligns to 4:427/429 of 8erbK
8wkoA Crystal structure of o-acetylhomoserine sulfhydrylase from lactobacillus plantarum in the closed form
48% identity, 99% coverage: 3:427/430 of query aligns to 9:424/425 of 8wkoA
8ovhA Crystal structure of o-acetyl-l-homoserine sulfhydrolase from saccharomyces cerevisiae in complex with pyridoxal-5'-phosphate (see paper)
47% identity, 99% coverage: 3:426/430 of query aligns to 5:392/400 of 8ovhA
5x2xA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-homocysteine intermediates (see paper)
41% identity, 98% coverage: 7:426/430 of query aligns to 8:389/392 of 5x2xA
5x2wA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-methionine intermediates (see paper)
41% identity, 98% coverage: 7:426/430 of query aligns to 8:389/392 of 5x2wA
5x30C Crystal structure of pseudomonas putida methionine gamma-lyase c116h mutant with l-homocysteine intermediates. (see paper)
41% identity, 98% coverage: 7:426/430 of query aligns to 9:390/393 of 5x30C
3vk3A Crystal structure of l-methionine gamma-lyase from pseudomonas putida c116h mutant complexed with l-methionine (see paper)
41% identity, 98% coverage: 7:426/430 of query aligns to 13:394/397 of 3vk3A
1pg8A Crystal structure of l-methionine alpha-, gamma-lyase
41% identity, 98% coverage: 7:426/430 of query aligns to 14:395/398 of 1pg8A
P13254 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-methioninase; EC 4.4.1.11; EC 4.4.1.2 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
41% identity, 98% coverage: 7:426/430 of query aligns to 14:395/398 of P13254
4hf8A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with glycine (see paper)
40% identity, 98% coverage: 8:428/430 of query aligns to 13:395/396 of 4hf8A
4omaA The crystal structure of methionine gamma-lyase from citrobacter freundii in complex with l-cycloserine pyridoxal-5'-phosphate (see paper)
40% identity, 98% coverage: 8:428/430 of query aligns to 13:395/396 of 4omaA
3jwbA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with norleucine (see paper)
40% identity, 98% coverage: 8:428/430 of query aligns to 13:395/396 of 3jwbA
3jwaA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with methionine phosphinate (see paper)
40% identity, 98% coverage: 8:428/430 of query aligns to 13:395/396 of 3jwaA
>200276 FitnessBrowser__MR1:200276
MKLESLALHHGYESEATTKAAAVPIYQTTSYTFDDTQHGADLFDLKVAGNIYTRIMNPTT
SVLEQRLAAIEGGIGALAVASGMAAITYAIQALTQVGDNIVSTSQLYGGTYNLFAHTLPR
QGVEVRMAAFDDFEELEALIDAKTKALFCESIGNPAGNIVDLKRLAEIAHKHGVPLIVDN
TVATPVLCRPFEHGADIVIHSLTKYIGGHGTTIGGIIIDSGKFDWVANKERFSLLNQADP
SYHGVVYTEAFGPAAFIGRCRVVPLRNTGAALSPHSAFLLLQGLETLSLRMERHCANALA
LAEYLILHPSVSWVNYGALPSSPFRENCEKITGGKASGIISFGIKAATPEEGKIAGGKFI
DALKMVLRLVNIGDAKSLACHPASTTHRQLDANELARAGVSEDLIRISVGIEHIDDIIAD
VSQALEKALV
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Lawrence Berkeley National Laboratory