Comparing 200788 SO1623 PTS system, glucose-specific IIBC component (NCBI ptt file) to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
P69786 PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199 from Escherichia coli (strain K12) (see 5 papers)
43% identity, 94% coverage: 22:489/499 of query aligns to 3:474/477 of P69786
P09323 PTS system N-acetylglucosamine-specific EIICBA component; EIICBA-Nag; EII-Nag; EC 2.7.1.193 from Escherichia coli (strain K12) (see paper)
35% identity, 92% coverage: 27:487/499 of query aligns to 6:464/648 of P09323
Sites not aligning to the query:
6bvgA Crystal structure of bcmalt t280c-e54c crosslinked by divalent mercury (see paper)
30% identity, 76% coverage: 25:404/499 of query aligns to 2:442/447 of 6bvgA
1o2fB Complex of enzyme iiaglc and iibglc phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure (see paper)
45% identity, 15% coverage: 415:489/499 of query aligns to 1:75/77 of 1o2fB
>200788 SO1623 PTS system, glucose-specific IIBC component (NCBI ptt file)
MAGKLESTRQIRARRLGHFVTQQWFKFAQRLSQALLIPIAILPAAGVMLGLTVSPIPFMP
EVLNVLMLAVGKLIFAIMPILFAVAVAIGFCRDQGIAAFTAVFGYGVMTATLAALADLYQ
LPTQLVLGMETLDTGIAGGMLIGGVTCFAVRWSQYIRLPAIFSFFEGRRSASLLIIPLAM
GLGYVLAHIWPSLSLLIERVSDWAVYQKPAIAFGVYGALERLLIPLGLHHIWNAPFYLEV
GQYQLQDAEVVRGEVARYLAGDPQAGNLAGGYLIKMWGLPAAALAIWRCADNSERNRVAG
IMLSAAAASWLTGVTEPIEFAFMFVAPLLFLIHVMLSGLAYFVCIMLDIHHSIVFSHGLV
DFTLLFSLSRNTGWFAVLGPLTAVIYYILFRGSILAFNLKTPGRLQSDGTKGSKESLRAI
IAALGGRDNIVELNACLTRLRLSVHSPELVNKVRLSQLGAKGVIVMGKGVQIVYGTKAET
LRKVLQRYLDTRRYEVNCR
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory