Comparing 200836 FitnessBrowser__MR1:200836 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2v6kA Structure of maleyl pyruvate isomerase, a bacterial glutathione-s- transferase in zeta class, in complex with substrate analogue dicarboxyethyl glutathione (see paper)
51% identity, 100% coverage: 1:215/216 of query aligns to 3:213/214 of 2v6kA
2jl4A Holo structure of maleyl pyruvate isomerase, a bacterial glutathione- s-transferase in zeta class (see paper)
51% identity, 100% coverage: 1:215/216 of query aligns to 1:211/212 of 2jl4A
O86043 Maleylpyruvate isomerase; MPI; Naphthalene degradation protein L; EC 5.2.1.4 from Ralstonia sp. (see paper)
51% identity, 100% coverage: 1:215/216 of query aligns to 1:211/212 of O86043
1fw1A Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
49% identity, 99% coverage: 2:215/216 of query aligns to 3:206/208 of 1fw1A
O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 10 papers)
48% identity, 99% coverage: 2:215/216 of query aligns to 7:210/216 of O43708
Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
45% identity, 99% coverage: 2:215/216 of query aligns to 7:210/216 of Q9WVL0
2cz2A Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
45% identity, 99% coverage: 2:215/216 of query aligns to 4:207/212 of 2cz2A
4pxoA Crystal structure of maleylacetoacetate isomerase from methylobacteriu extorquens am1 with bound malonate and gsh (target efi-507068)
43% identity, 99% coverage: 3:215/216 of query aligns to 5:214/216 of 4pxoA
4kaeA Crystal structure of maleylacetoacetate isomerase from anaeromyxobacter dehalogenans 2cp-1, target efi-507175, with bound dicarboxyethyl glutathione and citrate in the active site
41% identity, 99% coverage: 3:215/216 of query aligns to 10:212/220 of 4kaeA
4kdyA Crystal structure of maleylacetoacetate isomerase from anaeromyxobacter dehalogenans 2cp-1, target efi-507175, with bound gsh in the active site
41% identity, 99% coverage: 3:215/216 of query aligns to 12:214/222 of 4kdyA
D2YW48 Probable glutathione S-transferase; EC 2.5.1.18 from Coccidioides immitis (strain RS) (Valley fever fungus)
38% identity, 98% coverage: 3:214/216 of query aligns to 8:224/231 of D2YW48
3n5oA Crystal structure of putative glutathione transferase from coccidioides immitis bound to glutathione (see paper)
38% identity, 98% coverage: 3:214/216 of query aligns to 6:222/228 of 3n5oA
4pnfB Glutathione s-transferase from drosophila melanogaster - isozyme e6 (see paper)
31% identity, 96% coverage: 1:207/216 of query aligns to 3:200/221 of 4pnfB
4chsA Crystal structure of a tau class glutathione transferase 10 from glycine max (see paper)
28% identity, 80% coverage: 1:173/216 of query aligns to 4:158/215 of 4chsA
3m3mA Crystal structure of glutathione s-transferase from pseudomonas fluorescens [pf-5]
26% identity, 88% coverage: 3:191/216 of query aligns to 5:183/201 of 3m3mA
3qawA Crystal structure of a glutathione-s-transferase from antarctic clam laternula elliptica in a complex with glutathione (see paper)
25% identity, 98% coverage: 4:215/216 of query aligns to 4:209/219 of 3qawA
8a0rA Crystal structure of poplar glutathione transferase u20 in complex with pinocembrin (see paper)
39% identity, 45% coverage: 3:99/216 of query aligns to 4:92/215 of 8a0rA
Sites not aligning to the query:
8a0qA Crystal structure of poplar glutathione transferase u20 in complex with baicalein (see paper)
39% identity, 45% coverage: 3:99/216 of query aligns to 4:92/215 of 8a0qA
Sites not aligning to the query:
8a0oA Crystal structure of poplar glutathione transferase u20 in complex with galangin (see paper)
39% identity, 45% coverage: 3:99/216 of query aligns to 4:92/215 of 8a0oA
Sites not aligning to the query:
8a0iA Crystal structure of poplar glutathione transferase u20 in complex with glutathionylphenylacetophenone (see paper)
39% identity, 45% coverage: 3:99/216 of query aligns to 4:92/215 of 8a0iA
Sites not aligning to the query:
>200836 FitnessBrowser__MR1:200836
MILYGYWRSSAAYRVRIALNLKGVSAEQLSVHLVRDGGEQHKADYIALNPQELVPTLVVD
DEQDGDALTQSLAIIEYLDELYPKTPLLPASALERAHVRAMALTIACEIHPLNNLRVLQY
LTQKLTVNEEAKSAWYHHWVATGFTALETQLVRHSGRYCFGDKVTIADLCLVPQVYNAQR
FNVDLTPYPNIMRVWAECNQLPAFADAAPERQADAV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory