Comparing 201231 FitnessBrowser__MR1:201231 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
1q1kA Structure of atp-phosphoribosyltransferase from e. Coli complexed with pr-atp (see paper)
67% identity, 91% coverage: 30:323/324 of query aligns to 1:287/288 of 1q1kA
1h3dA Structure of the e.Coli atp-phosphoribosyltransferase (see paper)
67% identity, 91% coverage: 30:323/324 of query aligns to 1:287/288 of 1h3dA
4yb7A Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with atp (see paper)
65% identity, 91% coverage: 29:323/324 of query aligns to 1:295/296 of 4yb7A
4yb6A Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with the inhibitors amp and histidine (see paper)
65% identity, 91% coverage: 29:323/324 of query aligns to 1:295/296 of 4yb6A
4yb7C Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with atp (see paper)
65% identity, 91% coverage: 29:323/324 of query aligns to 1:293/294 of 4yb7C
7dahC Adenosine triphosphate phosphoribosyltransferase from vibrio cholerae in complex with atp and prpp
62% identity, 91% coverage: 29:323/324 of query aligns to 1:287/288 of 7dahC
4yb6E Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with the inhibitors amp and histidine (see paper)
64% identity, 91% coverage: 29:323/324 of query aligns to 1:292/293 of 4yb6E
5ubgA Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni with bound phosphoribosyl-atp (see paper)
64% identity, 69% coverage: 29:250/324 of query aligns to 1:222/222 of 5ubgA
5ub9A Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni (see paper)
65% identity, 68% coverage: 31:250/324 of query aligns to 2:220/220 of 5ub9A
5ubiA Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni with bound prpp (see paper)
64% identity, 67% coverage: 29:246/324 of query aligns to 1:218/218 of 5ubiA
2vd3A The structure of histidine inhibited hisg from methanobacterium thermoautotrophicum
32% identity, 90% coverage: 31:323/324 of query aligns to 4:288/289 of 2vd3A
5lhtA Atp phosphoribosyltransferase from mycobacterium tuberculosis in complex with the allosteric activator 3-(2-thienyl)-l-alanine (see paper)
29% identity, 89% coverage: 32:319/324 of query aligns to 2:279/284 of 5lhtA
5u99A Transition state analysis of adenosine triphosphate phosphoribosyltransferase (see paper)
30% identity, 89% coverage: 32:319/324 of query aligns to 4:273/278 of 5u99A
1nh8A Atp phosphoribosyltransferase (atp-prtase) from mycobacterium tuberculosis in complex with amp and histidine (see paper)
29% identity, 89% coverage: 32:319/324 of query aligns to 2:271/276 of 1nh8A
6czmE Crystal structure of medicago truncatula atp-phosphoribosyltransferase in tense form (see paper)
28% identity, 89% coverage: 32:319/324 of query aligns to 10:323/342 of 6czmE
1z7mE Atp phosphoribosyl transferase (hiszg atp-prtase) from lactococcus lactis (see paper)
32% identity, 54% coverage: 32:207/324 of query aligns to 2:164/200 of 1z7mE
6czmF Crystal structure of medicago truncatula atp-phosphoribosyltransferase in tense form (see paper)
27% identity, 89% coverage: 32:319/324 of query aligns to 3:296/315 of 6czmF
1z7nF Atp phosphoribosyl transferase (hiszg atp-prtase) from lactococcus lactis with bound prpp substrate (see paper)
32% identity, 54% coverage: 32:207/324 of query aligns to 2:168/205 of 1z7nF
1usyG Atp phosphoribosyl transferase (hisg:hisz) complex from thermotoga maritima (see paper)
35% identity, 54% coverage: 32:207/324 of query aligns to 2:160/203 of 1usyG
Sites not aligning to the query:
6fd9A Catalytic subunit hisg from psychrobacter arcticus atp phosphoribosyltransferase (hiszg atpprt) in complex with amp
31% identity, 64% coverage: 32:239/324 of query aligns to 4:200/209 of 6fd9A
>201231 FitnessBrowser__MR1:201231
MPISQLKRETKEYHFEFVNFERDRIMTESNRLRIAIQKSGRLSTDSQQLLKSCGVKFSIN
EQRLIAHADNMPIDLLRVRDDDIPGLVMDGVVDLGIIGENVLEEEQIERQTLNKPAEYVK
LRQLDFGACRLSLAVPTEFSYADASSLEGLRIATSYPNLLRRFMQQKSINYRDCMLKGSV
EVAPRAGLADGICDLVSTGATLEANGLYETEVIYRSMACIIQSTQTQAPSKQALIDRILS
RVNGVIRARESKYILLHAPTETLDQIVALLPGAENPTVLPLNDDTNRVAIHAVSTEDLFW
DTMEQLTALGASSILVMPIEKMMG
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory