SitesBLAST – Find functional sites

 

SitesBLAST

Comparing 209323 MicrobesOnline__882:209323 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

4ymtC Crystal structure of an amino acid abc transporter complex with arginines (see paper)
34% identity, 91% coverage: 13:216/225 of query aligns to 13:215/215 of 4ymtC

query
sites
4ymtC
P
 
P
Y
 
L
I
 
F
L
 
I
E
 
S
G
 
G
S
 
L
A
 
I
V
 
M
T
 
T
I
 
L
A
 
K
T
 
L
V
 
T
L
 
F
G
 
L
S
 
A
L
 
V
A
 
T
L
 
I
G
 
G
F
 
V
C
 
L
M
 
M
G
 
G
V
 
L
P
 
F
M
 
I
A
 
A
V
 
L
A
 
M
Q
 
K
V
 
M
Y
 
S
G
 
S
G
 
I
R
 
K
P
 
P
V
 
I
R
 
K
Y
 
L
L
 
V
V
 
A
G
 
S
L
 
S
Y
 
Y
V
 
I
W
 
E
F
 
V
F
 
I
R
 
R
G
 
G
M
 
T
P
|
P
I
x
L
L
 
L
V
 
V
L
 
Q
L
 
L
F
 
L
L
 
L
F
 
I
Y
 
Y
F
 
N
G
 
G
L
 
L
F
 
M
Q
 
Q
A
 
-
L
 
F
D
 
G
L
 
M
N
 
N
L
 
I
S
 
P
A
 
A
F
 
F
T
 
T
A
 
A
S
 
G
C
 
V
L
 
S
V
 
A
L
 
L
G
 
A
M
 
I
A
x
N
S
 
S
A
 
S
A
 
A
Y
|
Y
Q
 
V
S
 
A
Q
 
E
I
 
I
F
 
I
R
 
R
G
 
A
S
 
G
I
 
I
L
 
Q
A
 
A
L
 
V
P
 
D
Q
 
P
G
 
G
Q
 
Q
L
 
N
K
 
E
A
 
A
A
 
A
R
 
R
A
 
S
L
 
L
G
 
G
M
 
M
S
 
T
D
 
H
G
 
A
A
 
M
A
 
A
I
 
M
R
 
R
S
 
Y
I
 
V
V
 
I
L
 
I
P
 
P
Q
 
Q
A
 
A
L
 
I
R
 
K
L
 
N
S
 
I
I
 
L
P
 
P
A
 
A
W
 
L
S
 
G
N
 
N
E
|
E
Y
 
F
S
 
I
I
 
V
L
x
M
L
 
L
K
|
K
D
x
E
S
 
S
A
 
A
L
 
I
A
 
V
F
 
S
V
 
V
L
 
I
G
 
G
T
 
F
P
 
A
E
 
D
I
 
L
M
 
T
A
 
R
R
 
Q
T
 
A
H
 
D
F
 
I
V
 
I
A
 
Q
S
 
S
R
 
V
T
 
T
Y
 
Y
E
 
R
H
 
Y
L
 
F
P
 
E
L
 
P
Y
 
Y
M
 
I
T
 
I
A
 
I
G
 
A
A
 
A
L
 
I
Y
 
Y
F
 
F
I
 
V
I
 
M
T
 
T
L
 
L
A
 
T
G
 
F
L
 
S
K
 
K
V
 
L
L
 
L
R
 
S
H
 
L
L
 
F
E
 
E
R
 
R
K
 
R
T
 
L
R
 
R

4ymwC Crystal structure of an amino acid abc transporter with histidines (see paper)
34% identity, 90% coverage: 13:214/225 of query aligns to 13:213/214 of 4ymwC

query
sites
4ymwC
P
 
P
Y
 
L
I
 
F
L
 
I
E
 
S
G
 
G
S
 
L
A
 
I
V
 
M
T
 
T
I
 
L
A
 
K
T
 
L
V
 
T
L
 
F
G
 
L
S
 
A
L
 
V
A
 
T
L
 
I
G
 
G
F
 
V
C
 
L
M
 
M
G
 
G
V
 
L
P
 
F
M
 
I
A
 
A
V
 
L
A
 
M
Q
 
K
V
 
M
Y
 
S
G
 
S
G
 
I
R
 
K
P
 
P
V
 
I
R
 
K
Y
 
L
L
 
V
V
 
A
G
 
S
L
 
S
Y
 
Y
V
 
I
W
 
E
F
 
V
F
 
I
R
 
R
G
 
G
M
 
T
P
 
P
I
 
L
L
 
L
V
 
V
L
 
Q
L
 
L
F
 
L
L
 
L
F
 
I
Y
 
Y
F
 
N
G
 
G
L
 
L
F
 
M
Q
 
Q
A
 
-
L
 
F
D
 
G
L
 
M
N
 
N
L
 
I
S
 
P
A
 
A
F
 
F
T
 
T
A
 
A
S
 
G
C
 
V
L
 
S
V
 
A
L
 
L
G
 
A
M
 
I
A
x
N
S
 
S
A
 
S
A
 
A
Y
|
Y
Q
 
V
S
 
A
Q
 
E
I
 
I
F
 
I
R
 
R
G
 
A
S
 
G
I
 
I
L
 
Q
A
 
A
L
 
V
P
 
D
Q
 
P
G
 
G
Q
 
Q
L
 
N
K
 
E
A
 
A
A
 
A
R
 
R
A
 
S
L
 
L
G
 
G
M
 
M
S
 
T
D
 
H
G
 
A
A
 
M
A
 
A
I
 
M
R
 
R
S
 
Y
I
 
V
V
 
I
L
 
I
P
 
P
Q
 
Q
A
 
A
L
 
I
R
 
K
L
 
N
S
 
I
I
 
L
P
 
P
A
 
A
W
 
L
S
 
G
N
 
N
E
|
E
Y
 
F
S
 
I
I
 
V
L
 
M
L
 
L
K
 
K
D
x
E
S
 
S
A
 
A
L
 
I
A
 
V
F
 
S
V
 
V
L
 
I
G
 
G
T
 
F
P
 
A
E
 
D
I
 
L
M
 
T
A
 
R
R
 
Q
T
 
A
H
 
D
F
 
I
V
 
I
A
 
Q
S
 
S
R
 
V
T
 
T
Y
 
Y
E
 
R
H
 
Y
L
 
F
P
 
E
L
 
P
Y
 
Y
M
 
I
T
 
I
A
 
I
G
 
A
A
 
A
L
 
I
Y
 
Y
F
 
F
I
 
V
I
 
M
T
 
T
L
 
L
A
 
T
G
 
F
L
 
S
K
 
K
V
 
L
L
 
L
R
 
S
H
 
L
L
 
F
E
 
E
R
 
R
K
 
R

Query Sequence

>209323 MicrobesOnline__882:209323
MLDKLLVIWDALPYILEGSAVTIATVLGSLALGFCMGVPMAVAQVYGGRPVRYLVGLYVW
FFRGMPILVLLFLFYFGLFQALDLNLSAFTASCLVLGMASAAYQSQIFRGSILALPQGQL
KAARALGMSDGAAIRSIVLPQALRLSIPAWSNEYSILLKDSALAFVLGTPEIMARTHFVA
SRTYEHLPLYMTAGALYFIITLAGLKVLRHLERKTRIPGYAGYGI

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory