Comparing 349651 FitnessBrowser__Btheta:349651 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8a5eC Cryo-em structure of the electron bifurcating fe-fe hydrogenase hydabc complex from acetobacterium woodii in the reduced state (see paper)
54% identity, 91% coverage: 14:156/158 of query aligns to 13:155/156 of 8a5eC
8a6tC Cryo-em structure of the electron bifurcating fe-fe hydrogenase hydabc complex from thermoanaerobacter kivui in the reduced state (see paper)
52% identity, 92% coverage: 12:156/158 of query aligns to 5:149/151 of 8a6tC
7t2rC Structure of electron bifurcating ni-fe hydrogenase complex hydabcsl in fmn-free apo state (see paper)
48% identity, 95% coverage: 9:158/158 of query aligns to 3:152/152 of 7t2rC
O52681 Bifurcating [FeFe] hydrogenase gamma subunit; Hydrogenase (NAD(+), ferredoxin) gamma subunit; Iron-hydrogenase gamma subunit; EC 1.12.1.4 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
42% identity, 93% coverage: 12:158/158 of query aligns to 6:152/161 of O52681
7p5hC Tmhydabc- d2 map (see paper)
42% identity, 93% coverage: 12:158/158 of query aligns to 3:149/156 of 7p5hC
2auvA Solution structure of hndac : a thioredoxin-like [2fe-2s] ferredoxin involved in the NADP-reducing hydrogenase complex (see paper)
62% identity, 53% coverage: 73:156/158 of query aligns to 1:84/85 of 2auvA
8oh5A Cryo-em structure of the electron bifurcating transhydrogenase stnabc complex from sporomusa ovata (state 2) (see paper)
41% identity, 87% coverage: 20:157/158 of query aligns to 12:149/150 of 8oh5A
5gupE structure of mammalian respiratory supercomplex I1III2IV1 (see paper)
41% identity, 87% coverage: 21:158/158 of query aligns to 50:187/197 of 5gupE
Q9D6J6 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; NADH-ubiquinone oxidoreductase 24 kDa subunit; EC 7.1.1.2 from Mus musculus (Mouse) (see paper)
42% identity, 87% coverage: 22:158/158 of query aligns to 72:208/248 of Q9D6J6
7dgq9 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (see paper)
41% identity, 87% coverage: 21:158/158 of query aligns to 33:170/207 of 7dgq9
Sites not aligning to the query:
7v2cO Active state complex i from q10 dataset (see paper)
41% identity, 87% coverage: 21:158/158 of query aligns to 40:177/217 of 7v2cO
P04394 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; NADH dehydrogenase subunit II; NADH-ubiquinone oxidoreductase 24 kDa subunit; EC 7.1.1.2 from Bos taurus (Bovine) (see 2 papers)
42% identity, 87% coverage: 22:158/158 of query aligns to 73:209/249 of P04394
Sites not aligning to the query:
8eswV2 NADH dehydrogenase (Ubiquinone) 24 kDa subunit, isoform A (see paper)
41% identity, 87% coverage: 22:158/158 of query aligns to 38:174/214 of 8eswV2
Sites not aligning to the query:
8b9zE Drosophila melanogaster complex i in the active state (dm1) (see paper)
41% identity, 87% coverage: 22:158/158 of query aligns to 38:174/214 of 8b9zE
P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; NDUFV2; NADH-ubiquinone oxidoreductase 24 kDa subunit; EC 7.1.1.2 from Homo sapiens (Human) (see 2 papers)
41% identity, 87% coverage: 22:158/158 of query aligns to 73:209/249 of P19404
Sites not aligning to the query:
6vw8C Formate dehydrogenase fdsabg subcomplex fdsbg from c. Necator (see paper)
38% identity, 84% coverage: 26:157/158 of query aligns to 18:149/152 of 6vw8C
6r7pA Crystal structure of oxidized aquifex aeolicus nadh-quinone oxidoreductase subunits nuoe and nuof s96m (see paper)
37% identity, 91% coverage: 12:154/158 of query aligns to 7:153/157 of 6r7pA
6tg9G Cryo-em structure of nadh reduced form of NAD+-dependent formate dehydrogenase from rhodobacter capsulatus (see paper)
32% identity, 92% coverage: 13:157/158 of query aligns to 5:147/148 of 6tg9G
8e9gE Mycobacterial respiratory complex i with both quinone positions modelled (see paper)
31% identity, 94% coverage: 9:157/158 of query aligns to 23:175/233 of 8e9gE
7zmbH Cryoem structure of mitochondrial complex i from chaetomium thermophilum (state 2) (see paper)
35% identity, 83% coverage: 28:158/158 of query aligns to 45:177/221 of 7zmbH
>349651 FitnessBrowser__Btheta:349651
MSDIKLACDVVEQVKTICDKHGNNAGELINILHEAQHLHGYLPEEMQRIIASKLRIPVSK
VYGVVTFYTFFTMTPKGKHPISVCMGTACYVRGSEKLLEEFKRVLGIEVGETTPDGKYSL
DCLRCVGACGLAPVVMIGEKVYGRLQPVDVKKIIEELE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory