Comparing 350675 FitnessBrowser__Btheta:350675 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
4lhdA Crystal structure of synechocystis sp. Pcc 6803 glycine decarboxylase (p-protein), holo form with pyridoxal-5'-phosphate and glycine, closed flexible loop (see paper)
52% identity, 99% coverage: 4:941/949 of query aligns to 17:946/952 of 4lhdA
Sites not aligning to the query:
Q94B78 Glycine dehydrogenase (decarboxylating) 1, mitochondrial; Glycine cleavage system P protein 1; Glycine decarboxylase 1; Glycine decarboxylase P-protein 1; AtGLDP1; Glycine dehydrogenase (aminomethyl-transferring) 1; EC 1.4.4.2 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
52% identity, 99% coverage: 3:943/949 of query aligns to 76:1023/1037 of Q94B78
6i34B Crystal structure of neanderthal glycine decarboxylase (p-protein)
49% identity, 99% coverage: 2:943/949 of query aligns to 9:951/954 of 6i34B
6i35A Crystal structure of human glycine decarboxylase (p-protein) bound with pyridoxyl-glycine-5'-monophosphate
49% identity, 99% coverage: 2:943/949 of query aligns to 11:949/953 of 6i35A
6i33A Crystal structure of human glycine decarboxylase (p-protein)
49% identity, 99% coverage: 2:943/949 of query aligns to 11:946/950 of 6i33A
P15505 Glycine dehydrogenase (decarboxylating), mitochondrial; Glycine cleavage system P protein; Glycine decarboxylase; Glycine dehydrogenase (aminomethyl-transferring); EC 1.4.4.2 from Gallus gallus (Chicken) (see paper)
48% identity, 99% coverage: 2:943/949 of query aligns to 49:985/1004 of P15505
6i33B Crystal structure of human glycine decarboxylase (p-protein)
48% identity, 99% coverage: 2:943/949 of query aligns to 9:922/925 of 6i33B
1wyuB Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in holo form (see paper)
38% identity, 45% coverage: 450:875/949 of query aligns to 19:442/473 of 1wyuB
1wyvA Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in inhibitor-bound form (see paper)
37% identity, 36% coverage: 14:357/949 of query aligns to 7:346/437 of 1wyvA
1wyuA Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in holo form (see paper)
37% identity, 36% coverage: 14:357/949 of query aligns to 7:346/437 of 1wyuA
>350675 FitnessBrowser__Btheta:350675
MKTDLLASRHIGINEEDTAVMLRKIGVDSLDELINKTIPANIRLKEPLALAKPLTEYEFG
KHIADLASKNKLYTTYIGLGWYNTITPAVIQRNVFENPVWYTSYTPYQTEVSQGRLEALM
NFQTAVCDLTAMPLANCSLLDEATAAAEAVTMMYALRSRTQQKAGANVVFVDENIFPQTL
AVMTTRAIPQGIELRVGKYKEFEPSPEIFACILQYPNSSGNVEDYADFTKKAHEADCKVA
VAADILSLALLTPPGEWGADIVFGTTQRLGTPMFYGGPSAGYFATRDEYKRNMPGRIIGW
SKDKYGKLCYRMALQTREQHIKREKATSNICTAQALLATMAGFYAVYHGQEGIKTIASRI
HSITVFLDKQLKKFGYTQVNAQYFDTLRFELPEHVSAQQIRTIALSKEVNLRYYENGDVG
FSIDETTDIAATNVLLSIFAIAAGKDYQKVEDVPEKSNIDKALKRTTPFLTHEVFSNYHT
ETEMMRYIKRLDRKDISLAQSMISLGSCTMKLNAAAEMLPLSRPEFMSMHPLVPEDQAEG
YRELISNLSEDLKVITGFAGVSLQPNSGAAGEYAGLRVIRAYLESIGQGHRNKILIPASA
HGTNPASAIQAGFETVTCACDEQGNVDMGDLRAKAEENKEALAALMITYPSTHGIFETEI
KEICEIIHACGAQVYMDGANMNAQVGLTNPGFIGADVCHLNLHKTFASPHGGGGPGVGPI
CVAEHLVPFLPGHSIFGSTQNQVSAAPFGSAGILPITYGYIRMMGTEGLTQATKIAILNA
NYLAACLKDTYGIVYRGATGFVGHEMILECRKVHEETGISENDIAKRLMDYGYHAPTLSF
PVHGTLMIEPTESESLAELDNFVDVMLNIWKEIQEVKNEEADKNDNVLINAPHPEYEIVN
DNWEHSYTREKAAYPIESVRENKFWVNVARVDNTLGDRKLLPTRYGTFE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory