SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing 351605 FitnessBrowser__Btheta:351605 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 20 (the maximum) hits to proteins with known functional sites (download)

P09342 Acetolactate synthase 1, chloroplastic; ALS I; Acetohydroxy-acid synthase I; Acetolactate synthase I; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco) (see 2 papers)
41% identity, 99% coverage: 8:564/565 of query aligns to 96:660/667 of P09342

query
sites
P09342

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C161 (= C74) modified: Disulfide link with 307
P194 (≠ G107) mutation to Q: In C3; highly resistant to sulfonylurea herbicides.
C307 (≠ V218) modified: Disulfide link with 161

P09114 Acetolactate synthase 2, chloroplastic; ALS II; Acetohydroxy-acid synthase II; Acetolactate synthase II; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco) (see paper)
41% identity, 99% coverage: 8:564/565 of query aligns to 93:657/664 of P09114

query
sites
P09114

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P191 (≠ G107) mutation to A: In S4-Hra; highly resistant to sulfonylurea herbicides; when associated with L-568.
W568 (= W483) mutation to L: In S4-Hra; highly resistant to sulfonylurea herbicides; when associated with A-191.

6demA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide bensulfuron methyl (see paper)
39% identity, 99% coverage: 6:563/565 of query aligns to 12:576/597 of 6demA

query
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6demA

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F

L

A

P

K
|
K

N

D

A

V

Q

T

V

A

E

S

K

-

T

-

K

-

Y

-

E

-

P

-

T

-

K

-

Q

-

E

-

F

I

I

L

R

R

S

E

Y

S

V

I

P

P

V

I

-

N

-

T

-

L

P

P

D

S

T

V

D

S

E

E

-

F

-

T

-

S

E

E

S

A

V

I

K

K

A

R

A

A

E

N

L

I

I

L

N

N

N

K

A

A

E

K

R

K

P

P

L

I

V

I

L

Y

V

A

G
|
G

Q
x
A

G
|
G

V

I

E

-

L

L

G
x
N

S

N

A

E

Q

Q

-

G

-

P

E
x
K

E

L

L

L

R

K

I

E

F

L

I

A

E

D

K

K

A

A

D

N

M

I

P

P

A

V

G

T

C

T

T
|
T

L
|
L

L
x
Q

G

G

L

L

S

G

A

A

L

F

P

D

T

Q

D

R

H

D

P

P

L

K

N

S

K

L

G

D

M
|
M

L
|
L

G
|
G

M
|
M

H
|
H

G

G

N

S

L

A

G

A

P

A

N

N

I

T

N

A

T

I

N

Q

K

N

C

A

D

D

V

C

L

I

I

I

A

A

V

L

G
|
G

M
x
A

R
|
R

F

F

D
|
D

R
|
R

V
|
V

T

T

G

G

N

N

L

I

A

S

T

K

Y

F

A

A

K

P

Q

E

A

A

K

K

-

L

-

A

-

S

-

E

-

G

-

R

-

G

V

I

I

L

H

H

F
|
F

D
x
E

I
|
I

D

S

P

P

A

K

E
x
N

V

I

N

N

K

K

N

V

V

V

K

E

V

A

D

T

I

E

A

A

V

I

L

E

G
|
G

D
|
D

C
x
V

K

T

K

A

T

N

L

L

A

Q

A

S

V

F

T

I

G

P

L

L

L

V

K

D

-

S

-

I

K

E

N

N

R

R

H

-

T

P

E

E

W

W

V

F

D

N

S

K

F

I

K

N

E

E

Y

W

E

K

A

-

V

-

E

-

E

K

K

Y

V

P

I

Y

R

S

P

Y

E

Q

L

L

H

E

P

T

A

P

T

G

D

S

S

L

L

I

S

K

M

P

G

Q

E

T

V

L

V

I

R

K

A

E

V

I

S

S

E

D

A

Q

T

A

R

Q

-

T

-

Y

-

N

H

K

E

E

A

V

I

I

L

V

V

T

T

T

D

G

V
|
V

G
|
G

Q
|
Q

N
x
H

Q
|
Q

M
|
M

I

W

S

A

A

A

R

Q

Y

H

F

F

K

T

Y

W

T

T

R

Q

E

P

R

R

S

T

I

M

V

I

T

T

S

S

G
|
G

L
|
L

G
|
G

T

T

M
|
M

G

G

F

Y

G

G

L

L

P

P

A

A

I

I

G

G

A

A

T

Q

F

V

G

A

R

K

P

P

D

D

R

A

T

I

V

V

C

I

V

D

F

I

M

D

G
|
G

D
|
D

G
x
A

G
x
S

L

F

Q

N

M
|
M

N

T

I

L

Q

T

E

E

L

L

G

S

T

S

I

A

M

V

E

Q

Q

A

K

G

A

A

P

P

V

I

K

K

I

V

I

C

C

V

L

L

N

N

N
|
N

N

E

Y
x
E

L
x
Q

G
|
G

N
x
M

V
|
V

R

T

Q

Q

W
|
W

Q

Q

A

S

M

L

F

F

F

Y

N

E

R

H

R

R

Y

Y

S

S

F

H

T

T

P

H

M

Q

L

S

N

N

P

P

D

D

Y

F

M

M

K

K

I
x
L

A

A

S

E

A

S

Y

M

D
x
N

I
x
V

P

K

S

G

K

I

R

R

V

I

F

T

S

N

R

Q

E

Q

E

E

L

L

K

K

A

S

A

G

I

V

D

K

E

E

M

F

L

L

S

D

T

A

D

T

G

E

A

P

F

V

L

L

E

E

A

V

C

I

V

V

V

E

E

K

G

V

N

P

V

V

L

L

P

P

M

M

T

V

P

P

P
x
A

G

G

G

K

S

A

V

L

N

D

Q

D

M

F

L

I

L

L

active site: Y33 (= Y27), G35 (= G29), G36 (= G30), A37 (≠ S31), I38 (= I32), E59 (= E54), T82 (= T77), F121 (= F116), Q122 (= Q117), E123 (= E118), K171 (= K166), K228 (≠ E225), M264 (= M261), V291 (= V288), V407 (= V394), L432 (= L419), G433 (= G420), M435 (= M422), D460 (= D447), N487 (= N474), E489 (≠ Y476), Q490 (≠ L477), M492 (≠ N479), V493 (= V480), W496 (= W483), L518 (≠ I505), N523 (≠ D510), V524 (≠ I511)
binding methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate: M264 (= M261), D289 (= D286), R290 (= R287), M492 (≠ N479), V493 (= V480), W496 (= W483), A567 (≠ P554)
binding flavin-adenine dinucleotide: D100 (= D95), R161 (= R156), G217 (= G215), A218 (≠ Q216), G219 (= G217), N222 (≠ G221), T244 (= T241), L245 (= L242), Q246 (≠ L243), M261 (= M258), L262 (= L259), G263 (= G260), M264 (= M261), H265 (= H262), G284 (= G281), A285 (≠ M282), R286 (= R283), D288 (= D285), R290 (= R287), V291 (= V288), F316 (= F304), E317 (≠ D305), I318 (= I306), N322 (≠ E310), G335 (= G323), D336 (= D324), V337 (≠ C325), Q411 (= Q398), M412 (= M399), G430 (= G417), G431 (= G418)
binding magnesium ion: D460 (= D447), N487 (= N474), E489 (≠ Y476)
binding (3z)-4-{[(4-amino-2-methylpyrimidin-5-yl)methyl]amino}-3-mercaptopent-3-en-1-yl trihydrogen diphosphate: V407 (= V394), G408 (= G395), Q409 (= Q396), H410 (≠ N397), G433 (= G420), M435 (= M422), G459 (= G446), D460 (= D447), A461 (≠ G448), S462 (≠ G449), M465 (= M452), N487 (= N474), E489 (≠ Y476), Q490 (≠ L477), G491 (= G478), M492 (≠ N479), V493 (= V480)

6delA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide chlorimuron ethyl (see paper)
39% identity, 99% coverage: 6:563/565 of query aligns to 12:576/597 of 6delA

query
sites
6delA

I

L

T

T

G

G

A

G

E

E

A

I

M

F

M

H

R

E

S

M

L

M

E

L

H

R

Q

H

G

K

V

V

T

D

T

T

I

V

F

F

G

G

Y
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Y

P

A

G
|
G

S
x
A

I
|
I

M

L

P

P

T

V

F

F

D

D

A

A

L

I

Y

Y

D

N

H

-

Q

S

N

D

T

K

L

F

N

K

H

F

I

V

L

L

V

P

R

R

H

H

E
|
E

Q

Q

G

G

A

A

A

G

H

H

A

M

A

A

Q

E

G

G

Y

Y

A

A

R

R

V

A

S

S

G

G

K

K

V

P

G

G

V

V

C

V

L

L

V

V

T
|
T

S

S

G

G

P

P

G

G

A

A

T

T

N

N

T

V

I

I

T

T

G

P

I

M

A

A

D

D

A

A

M

L

I

M

D
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D

S

G

T

V

P

P

I

L

V

V

I

F

A

S

G

G

Q

Q

V

V

G

P

T

T

G

T

F

A

L

I

G

G

T

T

D

D

A

A

F
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F

Q
|
Q

E
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E

V

A

D

D

L

I

V

V

G

G

I

I

T

S

Q

R

P

S

I

C

A

T

K

K

W

W

S

N

Y

V

Q

M

I

V

R

K

R

N

A

V

E

A

D

E

V

L

A

P

W

R

A

R

I

I

A

N

R

E

A

A

F

F

Y

E

I

I

A

A

S

T

G

G

R
|
R

P

P

G

G

P

P

V

V

V

L

L

V

D

D

F

L

A

P

K
|
K

N

D

A

V

Q

T

V

A

E

S

K

-

T

-

K

-

Y

-

E

-

P

-

T

-

K

-

Q

-

E

-

F

I

I

L

R

R

S

E

Y

S

V

I

P

P

V

I

-

N

-

T

-

L

P

P

D

S

T

V

D

S

E

E

-

F

-

T

-

S

E

E

S

A

V

I

K

K

A

R

A

A

E

N

L

I

I

L

N

N

N

K

A

A

E

K

R

K

P

P

L

I

V

I

L

Y

V

A

G
|
G

Q
x
A

G
|
G

V

I

E

-

L

L

G
x
N

S

N

A

E

Q

Q

-

G

-

P

E
x
K

E

L

L

L

R

K

I

E

F

L

I

A

E

D

K

K

A

A

D

N

M

I

P

P

A

V

G

T

C

T

T
|
T

L
|
L

L
x
Q

G

G

L

L

S

G

A

A

L

F

P

D

T

Q

D

R

H

D

P

P

L

K

N

S

K

L

G

D

M
|
M

L
|
L

G
|
G

M
|
M

H
|
H

G

G

N

S

L

A

G

A

P

A

N

N

I

T

N

A

T

I

N

Q

K

N

C

A

D

D

V

C

L

I

I

I

A

A

V

L

G
|
G

M
x
A

R
|
R

F

F

D
|
D

R
|
R

V
|
V

T

T

G

G

N

N

L

I

A

S

T

K

Y

F

A

A

K

P

Q

E

A

A

K

K

-

L

-

A

-

S

-

E

-

G

-

R

-

G

V

I

I

L

H

H

F
|
F

D
x
E

I
|
I

D

S

P

P

A

K

E
x
N

V

I

N

N

K

K

N

V

V

V

K

E

V

A

D

T

I

E

A

A

V

I

L

E

G
|
G

D
|
D

C
x
V

K

T

K

A

T

N

L

L

A

Q

A

S

V

F

T

I

G

P

L

L

L

V

K

D

-

S

-

I

K

E

N

N

R

R

H

-

T

P

E

E

W

W

V

F

D

N

S

K

F

I

K

N

E

E

Y

W

E

K

A

-

V

-

E

-

E

K

K

Y

V

P

I

Y

R

S

P

Y

E

Q

L

L

H

E

P

T

A

P

T

G

D

S

S

L

L

I

S

K

M

P

G

Q

E

T

V

L

V

I

R

K

A

E

V

I

S

S

E

D

A

Q

T

A

R

Q

-

T

-

Y

-

N

H

K

E

E

A

V

I

I

L

V

V

T

T

T

D

G

V
|
V

G
|
G

Q
|
Q

N
x
H

Q
|
Q

M
|
M

I

W

S

A

A

A

R

Q

Y

H

F

F

K

T

Y

W

T

T

R

Q

E

P

R

R

S

T

I

M

V

I

T

T

S

S

G
|
G

L
|
L

G
|
G

T

T

M
|
M

G

G

F

Y

G

G

L

L

P

P

A

A

I

I

G

G

A

A

T

Q

F

V

G

A

R

K

P

P

D

D

R

A

T

I

V

V

C

I

V

D

F

I

M

D

G
|
G

D
|
D

G
x
A

G
x
S

L

F

Q

N

M
|
M

N

T

I

L

Q

T

E

E

L

L

G

S

T

S

I

A

M

V

E

Q

Q

A

K

G

A

A

P

P

V

I

K

K

I

V

I

C

C

V

L

L

N

N

N
|
N

N

E

Y
x
E

L
x
Q

G
|
G

N
x
M

V
|
V

R

T

Q

Q

W
|
W

Q

Q

A

S

M

L

F

F

F

Y

N

E

R

H

R

R

Y

Y

S

S

F

H

T

T

P

H

M

Q

L

S

N

N

P

P

D

D

Y

F

M

M

K

K

I
x
L

A

A

S

E

A

S

Y

M

D
x
N

I
x
V

P

K

S

G

K

I

R

R

V

I

F

T

S

N

R

Q

E

Q

E

E

L

L

K

K

A

S

A

G

I

V

D

K

E

E

M

F

L

L

S

D

T

A

D

T

G

E

A

P

F

V

L

L

E

E

A

V

C

I

V

V

V

E

E

K

G

V

N

P

V

V

L

L

P

P

M

M

T

V

P

P

P

A

G

G

G

K

S

A

V

L

N

D

Q

D

M

F

L

I

L

L

active site: Y33 (= Y27), G35 (= G29), G36 (= G30), A37 (≠ S31), I38 (= I32), E59 (= E54), T82 (= T77), F121 (= F116), Q122 (= Q117), E123 (= E118), K171 (= K166), K228 (≠ E225), M264 (= M261), V291 (= V288), V407 (= V394), L432 (= L419), G433 (= G420), M435 (= M422), D460 (= D447), N487 (= N474), E489 (≠ Y476), Q490 (≠ L477), M492 (≠ N479), V493 (= V480), W496 (= W483), L518 (≠ I505), N523 (≠ D510), V524 (≠ I511)
binding 2-[[[[(4-chloro-6-methoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]benzoic acid ethyl ester: M264 (= M261), D289 (= D286), R290 (= R287), M492 (≠ N479), W496 (= W483)
binding flavin-adenine dinucleotide: D100 (= D95), R161 (= R156), G217 (= G215), A218 (≠ Q216), G219 (= G217), N222 (≠ G221), T244 (= T241), L245 (= L242), Q246 (≠ L243), M261 (= M258), L262 (= L259), G263 (= G260), M264 (= M261), H265 (= H262), G284 (= G281), A285 (≠ M282), R286 (= R283), D288 (= D285), R290 (= R287), V291 (= V288), F316 (= F304), E317 (≠ D305), I318 (= I306), N322 (≠ E310), G335 (= G323), D336 (= D324), V337 (≠ C325), Q411 (= Q398), M412 (= M399), G430 (= G417), G431 (= G418)
binding (3Z)-4-{[(4-amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}-3-sulfanylpent-3-en-1-yl trihydrogen diphosphate: V407 (= V394), G408 (= G395), Q409 (= Q396), H410 (≠ N397), G433 (= G420), M435 (= M422), G459 (= G446), D460 (= D447), A461 (≠ G448), S462 (≠ G449), M465 (= M452), N487 (= N474), E489 (≠ Y476), Q490 (≠ L477), G491 (= G478), M492 (≠ N479), V493 (= V480)
binding magnesium ion: D460 (= D447), N487 (= N474), E489 (≠ Y476)
binding (3z)-4-{[(4-amino-2-methylpyrimidin-5-yl)methyl]amino}-3-mercaptopent-3-en-1-yl trihydrogen diphosphate: V407 (= V394), G408 (= G395), Q409 (= Q396), H410 (≠ N397), G433 (= G420), M435 (= M422), G459 (= G446), D460 (= D447), A461 (≠ G448), S462 (≠ G449), M465 (= M452), N487 (= N474), E489 (≠ Y476), Q490 (≠ L477), G491 (= G478), M492 (≠ N479), V493 (= V480)

6deoA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron methyl (see paper)
39% identity, 99% coverage: 6:563/565 of query aligns to 10:572/593 of 6deoA

query
sites
6deoA

I

L

T

T

G

G

A

G

E

E

A

I

M

F

M

H

R

E

S

M

L

M

E

L

H

R

Q

H

G

K

V

V

T

D

T

T

I

V

F

F

G

G

Y
|
Y

P

A

G
|
G

S
x
A

I
|
I

M

L

P

P

T

V

F

F

D

D

A

A

L

I

Y

Y

D

N

H

-

Q

S

N

D

T

K

L

F

N

K

H

F

I

V

L

L

V

P

R

R

H

H

E
|
E

Q

Q

G

G

A

A

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A

A

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E

G

G

Y

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A

A

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L

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-

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x
V

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I

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-

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N

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D

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x
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I

C

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L

L

N

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N
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N

N

E

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x
E

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G

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x
M

V
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V

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Q

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A

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M

L

F

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F

Y

N

E

R

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R

R

Y

Y

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T

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H

M

Q

L

S

N

N

P

P

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D

Y

F

M

M

K

K

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x
L

A

A

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E

A

S

Y

M

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x
N

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x
V

P

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K

I

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I

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N

R

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Q

E

E

L

L

K

K

A

S

A

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I

V

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K

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T

A

D

T

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E

A

P

F

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L

E

E

A

V

C

I

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E

E

K

G

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N

P

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V

L

L

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M

T

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A

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G

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I

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L

active site: Y31 (= Y27), G33 (= G29), G34 (= G30), A35 (≠ S31), I36 (= I32), E57 (= E54), T80 (= T77), F119 (= F116), Q120 (= Q117), E121 (= E118), K169 (= K166), K224 (≠ E225), M260 (= M261), V287 (= V288), V403 (= V394), L428 (= L419), G429 (= G420), M431 (= M422), D456 (= D447), N483 (= N474), E485 (≠ Y476), Q486 (≠ L477), M488 (≠ N479), V489 (= V480), W492 (= W483), L514 (≠ I505), N519 (≠ D510), V520 (≠ I511)
binding flavin-adenine dinucleotide: D98 (= D95), R159 (= R156), G213 (= G215), A214 (≠ Q216), G215 (= G217), N218 (≠ G221), T240 (= T241), L241 (= L242), Q242 (≠ L243), M257 (= M258), L258 (= L259), G259 (= G260), M260 (= M261), H261 (= H262), G280 (= G281), A281 (≠ M282), R282 (= R283), D284 (= D285), R286 (= R287), V287 (= V288), F312 (= F304), E313 (≠ D305), I314 (= I306), N318 (≠ E310), G331 (= G323), D332 (= D324), V333 (≠ C325), Q407 (= Q398), M408 (= M399), G426 (= G417), G427 (= G418)
binding methyl 2-{[(4-iodo-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}benzoate: M260 (= M261), D285 (= D286), R286 (= R287), M488 (≠ N479), V489 (= V480), W492 (= W483)
binding magnesium ion: D456 (= D447), N483 (= N474), E485 (≠ Y476)
binding (3z)-4-{[(4-amino-2-methylpyrimidin-5-yl)methyl]amino}-3-mercaptopent-3-en-1-yl trihydrogen diphosphate: V403 (= V394), G404 (= G395), Q405 (= Q396), H406 (≠ N397), G429 (= G420), M431 (= M422), G455 (= G446), D456 (= D447), A457 (≠ G448), S458 (≠ G449), M461 (= M452), N483 (= N474), E485 (≠ Y476), Q486 (≠ L477), G487 (= G478), M488 (≠ N479), V489 (= V480)

6denA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron ethyl (see paper)
39% identity, 99% coverage: 6:563/565 of query aligns to 14:578/599 of 6denA

query
sites
6denA

I

L

T

T

G

G

A

G

E

E

A

I

M

F

M

H

R

E

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L

M

E

L

H

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H

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K

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F

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Y
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P

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G

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x
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I
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I

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L

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V

F

F

D

D

A

A

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Y

D

N

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-

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S

N

D

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K

L

F

N

K

H

F

I

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E
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E

Q

Q

G

G

A

A

A

G

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H

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M

A

A

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E

G

G

Y

Y

A

A

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A

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G

G

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K

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G

G

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C

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L

L

V

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T
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S

S

G

G

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P

G

G

A

A

T

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N

N

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A

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H

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A

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V

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I

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L

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H

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G

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G

G

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L

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P

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A

I

I

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R

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D

D

R

A

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I

V

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V

D

F

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M

D

G
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G

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G
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S

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N

M

M

N

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I

L

Q

T

E

E

L

L

G

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T

S

I

A

M

V

E

Q

Q

A

K

G

A

A

P

P

V

I

K

K

I

V

I

C

C

V

L

L

N

N

N
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N

E

Y
x
E

L
x
Q

G
|
G

N
x
M

V
|
V

R

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Q

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W
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W

Q

Q

A

S

M

L

F

F

F

Y

N

E

R

H

R

R

Y

Y

S

S

F

H

T

T

P

H

M

Q

L

S

N

N

P

P

D

D

Y

F

M

M

K

K

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x
L

A

A

S

E

A

S

Y

M

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x
N

I
x
V

P

K

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G

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I

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R

V

I

F

T

S

N

R

Q

E

Q

E

E

L

L

K

K

A

S

A

G

I

V

D

K

E

E

M

F

L

L

S

D

T

A

D

T

G

E

A

P

F

V

L

L

E

E

A

V

C

I

V

V

V

E

E

K

G

V

N

P

V

V

L

L

P

P

M

M

T

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P

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A

G

G

G

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A

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D

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M

F

L

I

L

L

active site: Y35 (= Y27), G37 (= G29), G38 (= G30), A39 (≠ S31), I40 (= I32), E61 (= E54), T84 (= T77), F123 (= F116), Q124 (= Q117), E125 (= E118), K173 (= K166), K230 (≠ E225), M266 (= M261), V293 (= V288), V409 (= V394), L434 (= L419), G435 (= G420), M437 (= M422), D462 (= D447), N489 (= N474), E491 (≠ Y476), Q492 (≠ L477), M494 (≠ N479), V495 (= V480), W498 (= W483), L520 (≠ I505), N525 (≠ D510), V526 (≠ I511)
binding flavin-adenine dinucleotide: D102 (= D95), R163 (= R156), G219 (= G215), A220 (≠ Q216), G221 (= G217), N224 (≠ G221), T246 (= T241), L247 (= L242), Q248 (≠ L243), M263 (= M258), L264 (= L259), G265 (= G260), M266 (= M261), H267 (= H262), G286 (= G281), A287 (≠ M282), R288 (= R283), D290 (= D285), R292 (= R287), V293 (= V288), F318 (= F304), E319 (≠ D305), I320 (= I306), N324 (≠ E310), G337 (= G323), D338 (= D324), V339 (≠ C325), Q413 (= Q398), M414 (= M399), G432 (= G417), G433 (= G418)
binding ethyl 2-{[(4-iodo-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}benzoate: M266 (= M261), D291 (= D286), R292 (= R287), M494 (≠ N479), W498 (= W483)
binding magnesium ion: D462 (= D447), N489 (= N474), E491 (≠ Y476)
binding (3z)-4-{[(4-amino-2-methylpyrimidin-5-yl)methyl]amino}-3-mercaptopent-3-en-1-yl trihydrogen diphosphate: V409 (= V394), G410 (= G395), Q411 (= Q396), H412 (≠ N397), G435 (= G420), M437 (= M422), G461 (= G446), D462 (= D447), A463 (≠ G448), S464 (≠ G449), N489 (= N474), E491 (≠ Y476), Q492 (≠ L477), G493 (= G478), M494 (≠ N479), V495 (= V480)

6derA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide metosulam (see paper)
39% identity, 99% coverage: 6:563/565 of query aligns to 14:579/600 of 6derA

query
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