Comparing 351932 FitnessBrowser__Btheta:351932 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P0A962 L-asparaginase 1; L-asparaginase I; L-ASNase I; L-asparagine amidohydrolase I; EC 3.5.1.1 from Escherichia coli (strain K12) (see paper)
46% identity, 94% coverage: 21:326/327 of query aligns to 42:335/338 of P0A962
Sites not aligning to the query:
6nxcB Ecai(t162a) mutant in complex with citrate at ph 4 (see paper)
45% identity, 94% coverage: 21:326/327 of query aligns to 41:334/336 of 6nxcB
Sites not aligning to the query:
2himA Crystal structure and allosteric regulation of the cytoplasmic escherichia coli l-asparaginase i (see paper)
45% identity, 94% coverage: 21:326/327 of query aligns to 35:323/324 of 2himA
Sites not aligning to the query:
7r6bB Crystal structure of mutant r43d/l124d/r125a/c273s of l-asparaginase i from yersinia pestis (see paper)
43% identity, 94% coverage: 21:326/327 of query aligns to 37:300/301 of 7r6bB
4r8lA Crystal structure of the asp-bound guinea pig l-asparaginase 1 catalytic domain (see paper)
42% identity, 89% coverage: 36:327/327 of query aligns to 71:353/354 of 4r8lA
Sites not aligning to the query:
5dndD Crystal structure of the asn-bound guinea pig l-asparaginase 1 catalytic domain active site mutant t116a (see paper)
42% identity, 89% coverage: 36:327/327 of query aligns to 71:353/357 of 5dndD
Sites not aligning to the query:
5ot0A The thermostable l-asparaginase from thermococcus kodakarensis (see paper)
36% identity, 87% coverage: 41:326/327 of query aligns to 52:326/328 of 5ot0A
Sites not aligning to the query:
4q0mA Crystal structure of pyrococcus furiosus l-asparaginase (see paper)
32% identity, 87% coverage: 41:325/327 of query aligns to 51:325/327 of 4q0mA
Sites not aligning to the query:
Q8TZE8 L-asparaginase; EC 3.5.1.1 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see 2 papers)
32% identity, 87% coverage: 41:325/327 of query aligns to 50:324/326 of Q8TZE8
Sites not aligning to the query:
1zq1A Structure of gatde tRNA-dependent amidotransferase from pyrococcus abyssi (see paper)
33% identity, 98% coverage: 7:326/327 of query aligns to 110:427/437 of 1zq1A
Sites not aligning to the query:
5b5uA Crystal structure of truncated pyrococcus furiosus l-asparaginase with peptide (see paper)
36% identity, 40% coverage: 41:171/327 of query aligns to 50:173/175 of 5b5uA
Sites not aligning to the query:
4njeA Crystal structure of pyrococcus furiosus l-asparaginase with ligand (see paper)
36% identity, 40% coverage: 41:171/327 of query aligns to 50:173/182 of 4njeA
Sites not aligning to the query:
7r5qA Escherichia coli type ii asparaginase n24s mutant in complex with glu (see paper)
33% identity, 38% coverage: 43:166/327 of query aligns to 38:156/306 of 7r5qA
Sites not aligning to the query:
1ho3A Crystal structure analysis of e. Coli l-asparaginase ii (y25f mutant) (see paper)
33% identity, 38% coverage: 43:166/327 of query aligns to 58:176/326 of 1ho3A
Sites not aligning to the query:
P00805 L-asparaginase 2; L-asparaginase II; L-ASNase II; L-asparagine amidohydrolase II; Colaspase; EC 3.5.1.1 from Escherichia coli (strain K12) (see 5 papers)
33% identity, 38% coverage: 43:166/327 of query aligns to 80:198/348 of P00805
Sites not aligning to the query:
1jazA Crystal structure of monoclinic form of d90e mutant of escherichia coli asparaginase ii (see paper)
32% identity, 38% coverage: 43:166/327 of query aligns to 39:157/307 of 1jazA
Sites not aligning to the query:
P38986 L-asparaginase 1; L-asparaginase I; L-asparagine amidohydrolase I; ASP I; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
24% identity, 84% coverage: 41:314/327 of query aligns to 108:372/381 of P38986
8h4aB Blasnase-t13a/m57p
28% identity, 73% coverage: 65:304/327 of query aligns to 79:308/328 of 8h4aB
7c8xA Blasnase-t13a with l-asn (see paper)
28% identity, 73% coverage: 65:304/327 of query aligns to 78:307/319 of 7c8xA
Sites not aligning to the query:
7c8qA Blasnase-t13a with d-asn (see paper)
28% identity, 73% coverage: 65:304/327 of query aligns to 79:308/321 of 7c8qA
Sites not aligning to the query:
>351932 FitnessBrowser__Btheta:351932
MIENTATGALENFNFEQLQRHIPELQKFNFPIDTYQFDPPMDSSDMEPDMWRKLVHIIHE
NYDLYHGFVILHGTDTMAYTASALSFMLEGLDKPVILTGSQLPIGVLRTDGKENLMTSIE
IAAAQDKDGKALVPEVCIFFENHLMRGNRTTKMNAENFNAFRSFNYPVLAEAGIHIKYNQ
AQIHVNKSKQELVPHYLLDTNIVVLKLFPGIQENVIATMLGTKGLKAVVLETYGSGNAPR
KEWFIRRLCQASAQGIVIVNVTQCNAGMVEMERYETGYQLLQAGVVSGYDSTTESAVTKL
MFLLGHGYTPDEVRDCMNRSIAGEITL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory