Comparing 354107 FitnessBrowser__Btheta:354107 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 11 hits to proteins with known functional sites (download)
3wfaA Catalytic role of the calcium ion in gh97 inverting glycoside hydrolase
73% identity, 96% coverage: 25:717/719 of query aligns to 1:701/702 of 3wfaA
2zq0A Crystal structure of susb complexed with acarbose (see paper)
73% identity, 96% coverage: 25:717/719 of query aligns to 1:703/704 of 2zq0A
G8JZS4 Glucan 1,4-alpha-glucosidase SusB; Alpha-glucosidase SusB; Glucoamylase SusB; Starch-utilization system protein B; EC 3.2.1.3 from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) (see paper)
70% identity, 100% coverage: 1:717/719 of query aligns to 1:737/738 of G8JZS4
2jkpA Structure of a family 97 alpha-glucosidase from bacteroides thetaiotaomicron in complex with castanospermine (see paper)
74% identity, 95% coverage: 27:707/719 of query aligns to 2:687/687 of 2jkpA
2jkeA Structure of a family 97 alpha-glucosidase from bacteroides thetaiotaomicron in complex with deoxynojirimycin (see paper)
74% identity, 95% coverage: 27:707/719 of query aligns to 2:687/687 of 2jkeA
2d73A Crystal structure analysis of susb (see paper)
72% identity, 96% coverage: 27:717/719 of query aligns to 2:716/717 of 2d73A
5hqaA A glycoside hydrolase family 97 enzyme in complex with acarbose from pseudoalteromonas sp. Strain k8 (see paper)
41% identity, 94% coverage: 28:704/719 of query aligns to 2:658/662 of 5hqaA
5hq4A A glycoside hydrolase family 97 enzyme from pseudoalteromonas sp. Strain k8 (see paper)
41% identity, 94% coverage: 28:704/719 of query aligns to 2:658/662 of 5hq4A
Q8A6L0 Retaining alpha-galactosidase; BtGH97b; Melibiase; EC 3.2.1.22 from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) (see paper)
28% identity, 97% coverage: 4:704/719 of query aligns to 1:661/662 of Q8A6L0
5e1qB Mutant (d415g) gh97 alpha-galactosidase in complex with gal-lac (see paper)
27% identity, 94% coverage: 31:704/719 of query aligns to 9:643/644 of 5e1qB
5xfmA Crystal structure of beta-arabinopyranosidase (see paper)
22% identity, 93% coverage: 29:700/719 of query aligns to 9:628/632 of 5xfmA
>354107 FitnessBrowser__Btheta:354107
MKNMKILTTAVLCLLLSFSMGATAMAESITSPDGQLKLDFSVNVQGEPVYELTYKGKGVI
KPSKLGLELKNDPGLMNGFACIDTKTSTFDETWEPVWGEVKSIRNHYNEMAVTLNQKAQD
RNMIIRFRLYNDGLGFRYEFPQQKNLNYFVIKEEHSQFAMTGDHTAFWIPGDYDTQEYDY
TESRLTEIRGLMKGAITDNASQTSFSPTGVQTSLQMKTADGLYINLHEAALVDYSCMHLN
LDDKKLIFESWLTPDAMGDKGYMQTPCQSPWRTVIVSDDARDILASKLTLNLNEPCAYQD
VSWIKPVKYIGVWWEMITGKSSWAYTDDVYSVKLGQTDYSKTSPNGRHAANNDKVKRYID
FAAQHGFDQVLVEGWNEGWEDWFGKSKDYVFDFVTPYPDFDVKMLNAYAKEKGVKLMMHH
ETSASVRNYERHLDTAYQFMVDNGYNAVKSGYVGNIIPRGEHHYGQWMNNHYLYAVTKAA
DYKICVNAHEAVRPTGLCRTYPNLIGNESARGTEYEAFAGNKPFHTTLLPFTRQIGGPMD
YTPGIFDTRISFLDGKHSVVRTTLAKQLALYVTMYSPLQMAADLPESYERYPDAFQFIKD
VALDWDDSKYLEAEPGDYITVARKAKGTNHWFVGGITDENSRTAAFTLDFLEPDKEYVAT
LYADGKEADYEKNPTSYQIKKGIVTNKTKMSVKLARSGGFALSLIEAAPSDRKSIKKWK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory