Comparing 3606631 FitnessBrowser__Dino:3606631 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3lv0A Crystal structure of extragenic suppressor protein suhb from bartonella henselae, native
33% identity, 95% coverage: 6:256/264 of query aligns to 4:254/258 of 3lv0A
3luzA Crystal structure of extragenic suppressor protein suhb from bartonella henselae, via combined iodide sad molecular replacement (see paper)
32% identity, 95% coverage: 6:256/264 of query aligns to 4:236/238 of 3luzA
Sites not aligning to the query:
3luzB Crystal structure of extragenic suppressor protein suhb from bartonella henselae, via combined iodide sad molecular replacement (see paper)
34% identity, 82% coverage: 40:256/264 of query aligns to 28:232/234 of 3luzB
Sites not aligning to the query:
2p3nA Thermotoga maritima impase tm1415 (see paper)
32% identity, 92% coverage: 6:249/264 of query aligns to 4:239/256 of 2p3nA
O33832 Fructose-1,6-bisphosphatase/inositol-1-monophosphatase; FBPase/IMPase; Inositol-1-phosphatase; I-1-Pase; EC 3.1.3.11; EC 3.1.3.25 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
32% identity, 92% coverage: 6:249/264 of query aligns to 4:239/256 of O33832
P0ADG4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Escherichia coli (strain K12) (see 5 papers)
31% identity, 99% coverage: 4:264/264 of query aligns to 3:262/267 of P0ADG4
6ib8B Structure of a complex of suhb and nusa ar2 domain (see paper)
31% identity, 99% coverage: 4:264/264 of query aligns to 7:266/270 of 6ib8B
2qflA Structure of suhb: inositol monophosphatase and extragenic suppressor from e. Coli (see paper)
31% identity, 99% coverage: 4:264/264 of query aligns to 3:262/262 of 2qflA
6tqoT Rrn anti-termination complex (see paper)
31% identity, 99% coverage: 4:264/264 of query aligns to 3:254/255 of 6tqoT
Q9M8S8 Inositol-phosphate phosphatase; L-galactose 1-phosphate phosphatase; Myo-inositol monophosphatase; EC 3.1.3.25; EC 3.1.3.93 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
31% identity, 81% coverage: 17:229/264 of query aligns to 22:244/271 of Q9M8S8
5dw8A Crystal structure of 2'amp bound saimpase-ii
30% identity, 81% coverage: 40:253/264 of query aligns to 29:242/260 of 5dw8A
5j16A Crystal structure of inositol monophosphate bound saimpase-ii
29% identity, 81% coverage: 41:253/264 of query aligns to 26:238/258 of 5j16A
2bjiA High resolution structure of myo-inositol monophosphatase, the target of lithium therapy (see paper)
26% identity, 93% coverage: 10:255/264 of query aligns to 11:262/274 of 2bjiA
P20456 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Bos taurus (Bovine) (see paper)
26% identity, 93% coverage: 10:255/264 of query aligns to 13:264/277 of P20456
P29218 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Homo sapiens (Human) (see 5 papers)
26% identity, 93% coverage: 10:255/264 of query aligns to 13:264/277 of P29218
1imdA Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis (see paper)
26% identity, 93% coverage: 10:255/264 of query aligns to 9:260/266 of 1imdA
6zk0AAA human impase with ebselen (see paper)
26% identity, 93% coverage: 10:255/264 of query aligns to 10:261/274 of 6zk0AAA
4as4A Structure of human inositol monophosphatase 1 (see paper)
26% identity, 93% coverage: 10:255/264 of query aligns to 11:262/274 of 4as4A
2hhmA Structure of inositol monophosphatase, the putative target of lithium therapy (see paper)
26% identity, 93% coverage: 10:255/264 of query aligns to 9:260/272 of 2hhmA
1imbA Structural analysis of inositol monophosphatase complexes with substrates (see paper)
26% identity, 93% coverage: 10:255/264 of query aligns to 9:260/272 of 1imbA
>3606631 FitnessBrowser__Dino:3606631
MPAPDLALLIDAAQAAGRIAEKHWRQDPEAWDKAGGAGPVTEADLEVDRMLRTELLAARP
DYGWLSEETEDTPDRLDRERVFVVDPIDGTRSFMAGQRTFAHALAVVENGIPVAGVVYLP
LRDKLYTAARGAGAALNGTVLRISTRSEVAGATVLAARPNLEGHHWGGTPPALDRHFRSS
LAYRLALTGEGRFDAMLTLRNSWEWDIAAGCLIVEEAGGQTTDRHGAGLRFNNPSAQTKG
VVAANPRLHAELSAKLTSMSERSS
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory