Comparing 3606735 FitnessBrowser__Dino:3606735 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 18 hits to proteins with known functional sites (download)
P97084 Threonine-phosphate decarboxylase; L-threonine-O-3-phosphate decarboxylase; EC 4.1.1.81 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
27% identity, 96% coverage: 9:313/318 of query aligns to 8:339/364 of P97084
1lkcA Crystal structure of l-threonine-o-3-phosphate decarboxylase from salmonella enterica (see paper)
27% identity, 96% coverage: 9:313/318 of query aligns to 1:332/355 of 1lkcA
1lc8A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with its reaction intermediate (see paper)
27% identity, 96% coverage: 9:313/318 of query aligns to 2:333/356 of 1lc8A
1lc7A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with a substrate (see paper)
27% identity, 96% coverage: 9:313/318 of query aligns to 5:336/358 of 1lc7A
7szpA Crystal structure of histidinol-phosphate aminotransferase from klebsiella pneumoniae subsp. Pneumoniae (strain hs11286)
34% identity, 36% coverage: 123:235/318 of query aligns to 144:262/353 of 7szpA
Sites not aligning to the query:
1fg7A Crystal structure of l-histidinol phosphate aminotransferase with pyridoxal-5'-phosphate (see paper)
33% identity, 41% coverage: 123:251/318 of query aligns to 144:277/354 of 1fg7A
Sites not aligning to the query:
1fg3A Crystal structure of l-histidinol phosphate aminotransferase complexed with l-histidinol (see paper)
33% identity, 41% coverage: 123:251/318 of query aligns to 144:277/354 of 1fg3A
Sites not aligning to the query:
1geyA Crystal structure of histidinol-phosphate aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate (see paper)
33% identity, 41% coverage: 123:251/318 of query aligns to 130:263/335 of 1geyA
Sites not aligning to the query:
4wbtA Crystal structure of histidinol-phosphate aminotransferase from sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
32% identity, 25% coverage: 132:212/318 of query aligns to 162:254/369 of 4wbtA
Sites not aligning to the query:
P0DV65 L-serine phosphate decarboxylase; CobD homolog SMUL_1544; SmCobD; L-serine O-phosphate decarboxylase; L-Ser-P decarboxylase; Norcobamide biosynthesis protein SMUL_1544; Threonine phosphate decarboxylase-like enzyme; EC 4.1.1.- from Sulfurospirillum multivorans (strain DM 12446 / JCM 15788 / NBRC 109480) (see paper)
24% identity, 48% coverage: 76:229/318 of query aligns to 100:283/392 of P0DV65
Sites not aligning to the query:
2f8jA Crystal structure of histidinol-phosphate aminotransferase (ec 2.6.1.9) (imidazole acetol-phosphate transferase) (tm1040) from thermotoga maritima at 2.40 a resolution
23% identity, 46% coverage: 121:266/318 of query aligns to 136:284/335 of 2f8jA
Sites not aligning to the query:
Q9X0D0 Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
23% identity, 46% coverage: 121:266/318 of query aligns to 135:283/335 of Q9X0D0
1uu0A Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form) (see paper)
23% identity, 46% coverage: 121:266/318 of query aligns to 129:277/328 of 1uu0A
Sites not aligning to the query:
1uu1A Complex of histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form) (see paper)
23% identity, 46% coverage: 121:266/318 of query aligns to 130:278/329 of 1uu1A
Sites not aligning to the query:
1h1cA Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (see paper)
23% identity, 46% coverage: 121:266/318 of query aligns to 130:278/329 of 1h1cA
Sites not aligning to the query:
3ly1D Crystal structure of putative histidinol-phosphate aminotransferase (yp_050345.1) from erwinia carotovora atroseptica scri1043 at 1.80 a resolution
23% identity, 59% coverage: 122:309/318 of query aligns to 140:340/354 of 3ly1D
Sites not aligning to the query:
4r5zA Crystal structure of rv3772 encoded aminotransferase (see paper)
30% identity, 28% coverage: 130:218/318 of query aligns to 152:250/353 of 4r5zA
Sites not aligning to the query:
4r2nA Crystal structure of rv3772 in complex with its substrate (see paper)
30% identity, 28% coverage: 130:218/318 of query aligns to 152:250/353 of 4r2nA
Sites not aligning to the query:
>3606735 FitnessBrowser__Dino:3606735
MTASAPRDHGGGLDAAAARWGGTRDAWLDLSTGINPVSYPIPDIPGPDWTALPDESAFSD
LVAAARDFWAVPDGLDILPAPGASALIAALPGLVPASRVEIPGPTYNEHAAAFAAHGWAQ
GTGPGAAFVAVHPNNPNGRLWQAEEIPTDRALTVLDESFCDIAPEASLMPLAARPRTVIL
KSFGKFWGLAGLRLGFAIGQAETLAPLRDRIGPWAVSGPALRVGALALRDAGWAAKTRAR
LDRDAARLDALAKGFGWSVTGGTGLFRLYDTPDASAAQDRLARRQIWTRRFPYSDRWLRL
GLPGTEADWGRVARALTP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory