Comparing 3607737 FitnessBrowser__Dino:3607737 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
4f4fA X-ray crystal structure of plp bound threonine synthase from brucella melitensis
57% identity, 99% coverage: 1:458/463 of query aligns to 2:459/464 of 4f4fA
1kl7A Crystal structure of threonine synthase from yeast (see paper)
43% identity, 91% coverage: 3:422/463 of query aligns to 7:459/509 of 1kl7A
Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
43% identity, 91% coverage: 1:422/463 of query aligns to 5:462/514 of Q42598
8g1yA Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
37% identity, 92% coverage: 1:424/463 of query aligns to 5:442/496 of 8g1yA
1vb3A Crystal structure of threonine synthase from escherichia coli
32% identity, 99% coverage: 1:457/463 of query aligns to 1:424/428 of 1vb3A
>3607737 FitnessBrowser__Dino:3607737
MRYISTRGQAPAMAFHEAMLAGLASDGGLYVPETVPTLTEAEIRAMAGLPYEEIAFRVMM
PFLGNSFTEEEFRTDIATAYGGFGHDARAPLKQLGPNHFLLELFHGPTLAFKDFAMQLIG
QLFQRELTRRGSRVTIVGATSGDTGSAAIEAFRGIASVDVFILYPHGRVSEVQRRQMTTP
TEDNVHALALHGHFDDCQARLKDMFNDHGFRDGVRLAGVNSINWARVLAQVVYYFSAATS
LGAPDRKISFTVPTGNFGDIFAGYIARRMGLPIDTLVIATNQNDILHRCLTTGAYETDAV
IPSISPSMDIQVSSNFERLLFDVYDRDGAAVAQLMDELKTKGGFTLSQGALTRLREGFAS
GRASEDETSATITRARDTMNELLCPHSAVGVHVAEQHIEPGVPMVTLATAHPAKFPAAVE
AATGVHPPLPPRMETLYERPERLTEVPNDLGALQTLIRERIDP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory