Comparing 3607831 FitnessBrowser__Dino:3607831 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 15 hits to proteins with known functional sites (download)
O69315 Beta-galactosidase; Beta-gal; Lactase; EC 3.2.1.23 from Thermus thermophilus (see paper)
53% identity, 96% coverage: 5:615/635 of query aligns to 2:615/645 of O69315
1kwkA Crystal structure of thermus thermophilus a4 beta-galactosidase in complex with galactose (see paper)
53% identity, 96% coverage: 5:615/635 of query aligns to 2:615/644 of 1kwkA
1kwgA Crystal structure of thermus thermophilus a4 beta-galactosidase (see paper)
53% identity, 96% coverage: 5:615/635 of query aligns to 2:615/644 of 1kwgA
6lvwA Polyextremophilic beta-galactosidase from the antarctic haloarchaeon halorubrum lacusprofundi (see paper)
42% identity, 97% coverage: 4:622/635 of query aligns to 2:636/668 of 6lvwA
3ttyA Crystal structure of beta-galactosidase from bacillus circulans sp. Alkalophilus in complex with galactose (see paper)
28% identity, 97% coverage: 9:623/635 of query aligns to 15:646/675 of 3ttyA
3ttsA Crystal structure of beta-galactosidase from bacillus circulans sp. Alkalophilus (see paper)
28% identity, 97% coverage: 9:623/635 of query aligns to 15:646/675 of 3ttsA
4uzsA Crystal structure of bifidobacterium bifidum beta-galactosidase (see paper)
30% identity, 94% coverage: 6:603/635 of query aligns to 21:651/687 of 4uzsA
Sites not aligning to the query:
4ucfA Crystal structure of bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose (see paper)
30% identity, 94% coverage: 6:603/635 of query aligns to 20:646/682 of 4ucfA
Sites not aligning to the query:
8ibtA Crystal structure of gh42 beta-galactosidase bibga42a from bifidobacterium longum subspecies infantis e318s mutant in complex with lacto-n-tetraose (see paper)
32% identity, 74% coverage: 6:474/635 of query aligns to 22:481/694 of 8ibtA
5e9aB Crystal structure analysis of the cold-adamped beta-galactosidase from rahnella sp. R3 (see paper)
34% identity, 73% coverage: 6:466/635 of query aligns to 16:467/684 of 5e9aB
8ibsA Crystal structure of gh42 beta-galactosidase bibga42a from bifidobacterium longum subspecies infantis e160a/e318a mutant in complex with galactose (see paper)
32% identity, 74% coverage: 6:474/635 of query aligns to 22:481/691 of 8ibsA
4uniA Beta-(1,6)-galactosidase from bifidobacterium animalis subsp. Lactis bl-04 in complex with galactose (see paper)
32% identity, 75% coverage: 5:479/635 of query aligns to 19:486/689 of 4uniA
4uozA Beta-(1,6)-galactosidase from bifidobacterium animalis subsp. Lactis bl-04 nucleophile mutant e324a in complex with galactose (see paper)
32% identity, 75% coverage: 5:479/635 of query aligns to 18:485/688 of 4uozA
O31529 Beta-galactosidase YesZ; Beta-gal; Probable rhamnogalacturonan beta-galactosidase; EC 3.2.1.23 from Bacillus subtilis (strain 168) (see paper)
28% identity, 79% coverage: 3:504/635 of query aligns to 2:490/663 of O31529
5dfaA 3d structure of the e323a catalytic mutant of gan42b, a gh42 beta- galactosidase from g. Stearothermophilus (see paper)
29% identity, 74% coverage: 6:477/635 of query aligns to 17:486/685 of 5dfaA
>3607831 FitnessBrowser__Dino:3607831
MTRKLGVCYYPEHWPEDQWPRDAARMKDAGLTLVRIGEFAWSRLEPSPGDLRFDWLDRAI
SVLAEAGLEVVLGTPTATPPRWMLDRHPDMLAVDARGQPRKFGSRRHYCFSHPGYRAEAA
RIARLLGERYGRDPRIVAWQIDNEYGCHDTTLSYSDAARHGFRDWLAQRYQSTDALNRAW
GNVFWSMAYDRFDQIDLPNLTVTEPNPAHALAFRRYASDMVVAFNRAQVAALRPLTDAPL
IHNYMGRVTEFDHHAVGADLDIASWDSYPMGFLLDRVEAPADHKAAYLRQGDPDFQAFHH
DLYRGVGRDGRWWIMEQQPGPVNWAPWNPAPLPGMVRLWSHEAFAHGAEAVCFFRWRQAP
FAQEQMHAGLLRPDDSPAPGLEEAAALAADLPRLPDVSPSRAPVALVFDYPSQWAWEVQP
QGADFDYFALCFAMYRGLRKLGLSVDILPADPARLAGHDLILVPGLLHLSADMTAYLATT
QAQVLVGPRAGSKTPEMSIALPLGPNLQGLDATVTHVETLPPGAERALQRGGAAERWIEA
VETRAEILEETTEGAPVLIRTGRQHYLAAWPDPEAMGRILRDLCSRAGIQTTDMPEGVRQ
RVHGHHKLVVNYSSEMRVFENDALPPAGLVWKLIP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory