Comparing 3607832 Dshi_1240 SMP-30/Gluconolaconase/LRE domain protein (RefSeq) to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q9A9Z1 D-xylonolactone lactonase; Xylono-1,5-lactonase; EC 3.1.1.110 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see paper)
30% identity, 98% coverage: 8:286/286 of query aligns to 10:288/289 of Q9A9Z1
7pldB Caulobacter crescentus xylonolactonase with (r)-4-hydroxy-2- pyrrolidone (see paper)
30% identity, 98% coverage: 8:286/286 of query aligns to 10:288/289 of 7pldB
7plbB Caulobacter crescentus xylonolactonase with d-xylose (see paper)
30% identity, 98% coverage: 8:286/286 of query aligns to 10:288/289 of 7plbB
Q15493 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; EC 3.1.1.17 from Homo sapiens (Human) (see 2 papers)
27% identity, 93% coverage: 11:275/286 of query aligns to 14:287/299 of Q15493
3g4hA Crystal structure of human senescence marker protein-30 (zinc bound) (see paper)
27% identity, 93% coverage: 11:275/286 of query aligns to 12:285/297 of 3g4hA
4gncA Human smp30/gnl-1,5-ag complex (see paper)
27% identity, 93% coverage: 11:275/286 of query aligns to 13:286/298 of 4gncA
Sites not aligning to the query:
4gnaA Mouse smp30/gnl-xylitol complex (see paper)
27% identity, 92% coverage: 14:275/286 of query aligns to 15:285/297 of 4gnaA
4gn9A Mouse smp30/gnl-glucose complex (see paper)
27% identity, 92% coverage: 14:275/286 of query aligns to 15:285/297 of 4gn9A
4gn8A Mouse smp30/gnl-1,5-ag complex (see paper)
27% identity, 92% coverage: 14:275/286 of query aligns to 15:285/297 of 4gn8A
Sites not aligning to the query:
4gn7A Mouse smp30/gnl (see paper)
27% identity, 92% coverage: 14:275/286 of query aligns to 15:285/297 of 4gn7A
5gx1A Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 1.1 mgy (1st measurement) (see paper)
28% identity, 96% coverage: 12:286/286 of query aligns to 14:307/307 of 5gx1A
5d9bA Luciferin-regenerating enzyme solved by siras using xfel (refined against native data) (see paper)
28% identity, 96% coverage: 12:286/286 of query aligns to 14:307/307 of 5d9bA
7rizA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound 2-hydroxyquinoline (see paper)
29% identity, 63% coverage: 76:254/286 of query aligns to 98:287/306 of 7rizA
Sites not aligning to the query:
8dk0A Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound (s)gamma- valerolactone (see paper)
28% identity, 63% coverage: 76:254/286 of query aligns to 93:274/293 of 8dk0A
Sites not aligning to the query:
8djzA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound product (see paper)
28% identity, 63% coverage: 76:254/286 of query aligns to 93:274/293 of 8djzA
Sites not aligning to the query:
8djfA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound tetrahedral intermediate (see paper)
28% identity, 63% coverage: 76:254/286 of query aligns to 93:274/293 of 8djfA
Sites not aligning to the query:
7risA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound phosphate (see paper)
28% identity, 63% coverage: 76:254/286 of query aligns to 89:274/293 of 7risA
Sites not aligning to the query:
2dsoC Crystal structure of d138n mutant of drp35, a 35kda drug responsive protein from staphylococcus aureus (see paper)
26% identity, 53% coverage: 98:248/286 of query aligns to 135:293/323 of 2dsoC
Sites not aligning to the query:
Q99QV3 Lactonase drp35; EC 3.1.1.- from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
25% identity, 53% coverage: 98:248/286 of query aligns to 137:295/324 of Q99QV3
Sites not aligning to the query:
3dr2A Structural and functional analyses of xc5397 from xanthomonas campestris: a gluconolactonase important in glucose secondary metabolic pathways (see paper)
27% identity, 81% coverage: 4:235/286 of query aligns to 36:276/299 of 3dr2A
>3607832 Dshi_1240 SMP-30/Gluconolaconase/LRE domain protein (RefSeq)
MSATLYDDRPCALGEGPLWHPERQQLFWFDITGQRMLSRDGDTPLEWQFDEMVSAAGWVD
HDTLLIASETALVTFDLAEGESRFVAPLEADRPETRSNDGRADPWGGFWIGTMGKSAEPG
AGAIYRLFDGTLRRVVRDVTISNALCFDAAQSCAYYADTPTRQVMRLPLDGDGWPSGPAT
VAVDLRAEGLNPDGAVTDAAGNLWIAQWGAGRVACHAPDGTFLRALACGGRHSSCPAFGG
PDLDQLFITTAREGLSADDIAAAPENGCVFAAEGVARGLPEPRVIL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory