Comparing 3608039 Dshi_1446 aminotransferase class-III (RefSeq) to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5lh9D Amine transaminase crystal structure from an uncultivated pseudomonas species in the plp-bound (internal aldimine) form
38% identity, 97% coverage: 4:435/444 of query aligns to 14:445/449 of 5lh9D
5lhaA Amine transaminase crystal structure from an uncultivated pseudomonas species in the pmp-bound form
38% identity, 97% coverage: 4:435/444 of query aligns to 12:443/447 of 5lhaA
6io1B Crystal structure of a novel thermostable (s)-enantioselective omega- transaminase from thermomicrobium roseum (see paper)
38% identity, 95% coverage: 17:439/444 of query aligns to 35:447/448 of 6io1B
Sites not aligning to the query:
5kr6B Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
34% identity, 98% coverage: 4:436/444 of query aligns to 23:454/460 of 5kr6B
6fyqA The crystal structure of a new transaminase from the marine bacterium virgibacillus (see paper)
35% identity, 94% coverage: 19:435/444 of query aligns to 33:435/443 of 6fyqA
Sites not aligning to the query:
5kr5A Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
34% identity, 98% coverage: 4:437/444 of query aligns to 19:451/455 of 5kr5A
6s54A Transaminase from pseudomonas fluorescens (see paper)
34% identity, 95% coverage: 12:435/444 of query aligns to 29:448/453 of 6s54A
Sites not aligning to the query:
6gwiB The crystal structure of halomonas elongata amino-transferase (see paper)
35% identity, 94% coverage: 21:438/444 of query aligns to 37:445/450 of 6gwiB
Sites not aligning to the query:
Q94CE5 Gamma-aminobutyrate transaminase POP2, mitochondrial; AtGABA-T; Gamma-aminobutyric acid aminotransferase 1; Protein HEXENAL RESPONSE 1; Protein POLLEN-PISTIL INCOMPATIBILITY 2; AtPOP2; EC 2.6.1.96 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
33% identity, 96% coverage: 8:435/444 of query aligns to 64:488/504 of Q94CE5
5kr3A Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
33% identity, 94% coverage: 19:437/444 of query aligns to 39:452/458 of 5kr3A
5ghgB Transaminase w58l with smba
34% identity, 98% coverage: 8:441/444 of query aligns to 21:430/433 of 5ghgB
Sites not aligning to the query:
3gjuA Crystal structure of a putative aminotransferase (mll7127) from mesorhizobium loti maff303099 at 1.55 a resolution
32% identity, 99% coverage: 1:440/444 of query aligns to 24:458/458 of 3gjuA
Sites not aligning to the query:
3fcrA Crystal structure of putative aminotransferase (yp_614685.1) from silicibacter sp. Tm1040 at 1.80 a resolution
32% identity, 96% coverage: 1:428/444 of query aligns to 23:446/458 of 3fcrA
Sites not aligning to the query:
5kquC Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
34% identity, 94% coverage: 20:437/444 of query aligns to 39:453/459 of 5kquC
6zhkA Crystal structure of adenosylmethionine-8-amino-7-oxononanoate aminotransferase from methanocaldococcus jannaschii dsm 2661
33% identity, 95% coverage: 19:438/444 of query aligns to 34:436/438 of 6zhkA
Sites not aligning to the query:
6s4gA Crystal structure of the omega transaminase from chromobacterium violaceum in complex with pmp (see paper)
33% identity, 96% coverage: 19:444/444 of query aligns to 34:450/453 of 6s4gA
Sites not aligning to the query:
7q9xAAA Probable aminotransferase
33% identity, 96% coverage: 19:444/444 of query aligns to 35:451/455 of 7q9xAAA
4a6tC Crystal structure of the omega transaminase from chromobacterium violaceum in complex with plp (see paper)
33% identity, 96% coverage: 19:444/444 of query aligns to 35:451/455 of 4a6tC
Sites not aligning to the query:
4ba5A Crystal structure of omega-transaminase from chromobacterium violaceum (see paper)
33% identity, 96% coverage: 19:444/444 of query aligns to 7:423/427 of 4ba5A
4a6rA Crystal structure of the omega transaminase from chromobacterium violaceum in the apo form, crystallised from polyacrylic acid (see paper)
33% identity, 96% coverage: 19:444/444 of query aligns to 6:419/423 of 4a6rA
>3608039 Dshi_1446 aminotransferase class-III (RefSeq)
MAGHVFGRSAAQMPTAVAGAGCYIIDADGKRYLDGSGGAAVSCLGHDHPAVRAALHAQID
KIAFAHTGFFTSEPAEVLCDALIAAAPKGIEKVYLLSGGSESVEAALKLARQFFLETGEP
RRHRVIARRQSYHGNTLGALAAGGNAWRREKYAPLLVETYHIDPCYAYRHQAVGESDAAY
GRRAADALRTEIERLGPETVMAFIAEPVVGATAGAVPPAPGYFERIREICDEYGVLLILD
EVMCGMGRTGTLFACEQDGISPDIVTIAKGLGAGYAPIGAMLASGRIYDAIAQGSGSFQH
GHTYHGHPLAAAAAGAVVETLRAPGTMAQVRAKGATLQSRLEAALGQHSHVGDIRGRGLF
RGIELVEDRDTKRPLDPARKVSARIKAAAMARGLICYPGSGTIDGKHGDHILLAPPFIIE
DKQIDALVHMLAEAIDDAMAATQA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory