SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing 3610201 FitnessBrowser__Dino:3610201 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

O31645 PTS system mannose-specific EIIBCA component; EIIBCA-Man; EII-Man; EC 2.7.1.191 from Bacillus subtilis (strain 168) (see 2 papers)
30% identity, 68% coverage: 46:149/154 of query aligns to 546:650/650 of O31645

query
sites
O31645

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Sites not aligning to the query:

9 C→A: Appears to be unable to inactivate ManR, since ManR does not show any decrease in its DNA-binding activity in the presence of this mutant.
365 modified: Phosphoserine

Query Sequence

>3610201 FitnessBrowser__Dino:3610201
MDLSNLLVPEAVKVIGHLSSKKRLMQELSDIVCDAYGVCPVNAVDALQEREALGPTGVGH
GVALPHARLRDIDRVVGVFVRLDKPLPFDSVDRQPVDLVFGLFAPEDSGVAHLKALALVS
RTLRDPNICAKLRANGDPSTLYTVLTESESTRAA

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory