SitesBLAST – Find functional sites

 

SitesBLAST

Comparing 40 a.a. (MKVHRMPKGV...) to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

L8EBJ9 Cell division inhibitor MciZ; FtsZ assembly inhibitor; Mother cell inhibitor of FtsZ from Bacillus subtilis (strain 168) (see paper)
100% identity, 100% coverage: 1:40/40 of query aligns to 1:40/40 of L8EBJ9

query
sites
L8EBJ9
M
 
M
K
 
K
V
 
V
H
 
H
R
 
R
M
 
M
P
 
P
K
 
K
G
 
G
V
 
V
V
 
V
L
 
L
V
 
V
G
 
G
K
 
K
A
 
A
W
 
W
E
 
E
I
 
I
R
|
R
A
 
A
K
 
K
L
 
L
K
 
K
E
 
E
Y
 
Y
G
 
G
R
 
R
T
 
T
F
 
F
Q
 
Q
Y
 
Y
V
 
V
K
 
K
D
 
D
W
 
W
I
 
I
S
 
S
K
 
K
P
 
P

4u39L Crystal structure of ftsz:mciz complex from bacillus subtilis
100% identity, 75% coverage: 9:38/40 of query aligns to 1:30/30 of 4u39L

query
sites
4u39L
G
 
G
V
 
V
V
 
V
L
 
L
V
 
V
G
 
G
K
 
K
A
 
A
W
|
W
E
 
E
I
 
I
R
|
R
A
|
A
K
 
K
L
 
L
K
 
K
E
 
E
Y
 
Y
G
 
G
R
 
R
T
 
T
F
 
F
Q
 
Q
Y
 
Y
V
 
V
K
 
K
D
 
D
W
 
W
I
 
I
S
 
S

Query Sequence

>40 a.a. (MKVHRMPKGV...)
MKVHRMPKGVVLVGKAWEIRAKLKEYGRTFQYVKDWISKP

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory