Comparing 5209746 FitnessBrowser__PV4:5209746 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1fg7A Crystal structure of l-histidinol phosphate aminotransferase with pyridoxal-5'-phosphate (see paper)
45% identity, 95% coverage: 18:360/360 of query aligns to 7:352/354 of 1fg7A
1fg3A Crystal structure of l-histidinol phosphate aminotransferase complexed with l-histidinol (see paper)
45% identity, 95% coverage: 18:360/360 of query aligns to 7:352/354 of 1fg3A
7szpA Crystal structure of histidinol-phosphate aminotransferase from klebsiella pneumoniae subsp. Pneumoniae (strain hs11286)
44% identity, 96% coverage: 16:360/360 of query aligns to 5:352/353 of 7szpA
1geyA Crystal structure of histidinol-phosphate aminotransferase complexed with n-(5'-phosphopyridoxyl)-l-glutamate (see paper)
44% identity, 88% coverage: 39:354/360 of query aligns to 14:332/335 of 1geyA
3cq5B Histidinol-phosphate aminotransferase from corynebacterium glutamicum in complex with pmp (see paper)
35% identity, 73% coverage: 41:303/360 of query aligns to 30:311/366 of 3cq5B
3cq6A Histidinol-phosphate aminotransferase from corynebacterium glutamicum holo-form (plp covalently bound ) (see paper)
35% identity, 73% coverage: 41:303/360 of query aligns to 28:309/364 of 3cq6A
Sites not aligning to the query:
1uu0A Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form) (see paper)
34% identity, 77% coverage: 28:305/360 of query aligns to 7:281/328 of 1uu0A
1uu1A Complex of histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (apo-form) (see paper)
34% identity, 77% coverage: 28:305/360 of query aligns to 8:282/329 of 1uu1A
Sites not aligning to the query:
1h1cA Histidinol-phosphate aminotransferase (hisc) from thermotoga maritima (see paper)
34% identity, 77% coverage: 28:305/360 of query aligns to 8:282/329 of 1h1cA
2f8jA Crystal structure of histidinol-phosphate aminotransferase (ec 2.6.1.9) (imidazole acetol-phosphate transferase) (tm1040) from thermotoga maritima at 2.40 a resolution
34% identity, 77% coverage: 28:305/360 of query aligns to 14:288/335 of 2f8jA
Q9X0D0 Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; EC 2.6.1.9 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
34% identity, 77% coverage: 28:305/360 of query aligns to 13:287/335 of Q9X0D0
8bj3A Crystal structure of medicago truncatula histidinol-phosphate aminotransferase (hisn6) in complex with histidinol-phosphate (see paper)
31% identity, 93% coverage: 20:354/360 of query aligns to 5:353/360 of 8bj3A
4r8dA Crystal structure of rv1600 encoded aminotransferase in complex with plp-mes from mycobacterium tuberculosis
35% identity, 68% coverage: 58:303/360 of query aligns to 60:311/369 of 4r8dA
4r5zA Crystal structure of rv3772 encoded aminotransferase (see paper)
27% identity, 93% coverage: 20:354/360 of query aligns to 6:343/353 of 4r5zA
4r2nA Crystal structure of rv3772 in complex with its substrate (see paper)
27% identity, 93% coverage: 20:354/360 of query aligns to 6:343/353 of 4r2nA
3ly1D Crystal structure of putative histidinol-phosphate aminotransferase (yp_050345.1) from erwinia carotovora atroseptica scri1043 at 1.80 a resolution
28% identity, 76% coverage: 59:331/360 of query aligns to 46:321/354 of 3ly1D
4wbtA Crystal structure of histidinol-phosphate aminotransferase from sinorhizobium meliloti in complex with pyridoxal-5'-phosphate
27% identity, 91% coverage: 30:357/360 of query aligns to 27:361/369 of 4wbtA
1lkcA Crystal structure of l-threonine-o-3-phosphate decarboxylase from salmonella enterica (see paper)
27% identity, 85% coverage: 54:358/360 of query aligns to 42:347/355 of 1lkcA
Sites not aligning to the query:
1lc8A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with its reaction intermediate (see paper)
27% identity, 85% coverage: 54:358/360 of query aligns to 43:348/356 of 1lc8A
Sites not aligning to the query:
1lc7A Crystal structure of l-threonine-o-3-phosphate decarboxylase from s. Enterica complexed with a substrate (see paper)
27% identity, 85% coverage: 54:358/360 of query aligns to 46:351/358 of 1lc7A
Sites not aligning to the query:
>5209746 FitnessBrowser__PV4:5209746
MSVEAKMSVNATSLAERLARPELLTLEPYQSARRIGGEGQIWINANESPFINSDLDSLNR
YPECQPPELITRYAEYAGVSNQQVLTSRGADEAIELLIRTFCIPGRDSIACFGPTYGMYA
ISAKTFNVGVKALRLDDEYQLPQELCSQVGDAKLVFICNPNNPTGTVIAPDAIEAVIRSL
PDTLVVVDEAYIEFCPDYSVASLLDKYDNLIVLRTLSKAFALAGARCGFMLATPEVIEMV
MRVIAPYPVPLPVAKLAIDALSKDGIARMQTQVAQLKANGQRLADALREAGARVLPAYGN
FVLAYFDQANEIKVGEMQARLKQTGVVARAYKDPALADAIRFSFASDAQTETLIAILKAD
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory