Comparing 5209816 FitnessBrowser__PV4:5209816 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2xf4A Crystal structure of salmonella enterica serovar typhimurium ycbl (see paper)
59% identity, 98% coverage: 1:210/214 of query aligns to 1:210/210 of 2xf4A
7ev5A Crystal structure of bleg-1 b3 metallo-beta-lactamase (see paper)
37% identity, 97% coverage: 3:209/214 of query aligns to 2:208/209 of 7ev5A
2zwrB Crystal structure of ttha1623 from thermus thermophilus hb8 (see paper)
34% identity, 96% coverage: 4:208/214 of query aligns to 2:200/207 of 2zwrB
2zziA Crystal structure of ttha1623 in a di-iron-bound form (see paper)
34% identity, 95% coverage: 5:208/214 of query aligns to 1:198/198 of 2zziA
7l0bA Crystal structure of hydroxyacyl glutathione hydrolase (glob) from staphylococcus aureus, apoenzyme (see paper)
32% identity, 91% coverage: 14:208/214 of query aligns to 13:200/202 of 7l0bA
4ysbA Crystal structure of ethe1 from myxococcus xanthus (see paper)
30% identity, 90% coverage: 17:209/214 of query aligns to 17:191/225 of 4ysbA
3r2uB 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
27% identity, 91% coverage: 11:205/214 of query aligns to 15:210/336 of 3r2uB
Sites not aligning to the query:
3tp9A Crystal structure of alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains
31% identity, 69% coverage: 17:163/214 of query aligns to 19:160/473 of 3tp9A
6sg9FL uS3m (see paper)
24% identity, 91% coverage: 11:205/214 of query aligns to 62:294/320 of 6sg9FL
Sites not aligning to the query:
3r2uA 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
26% identity, 91% coverage: 11:205/214 of query aligns to 13:222/348 of 3r2uA
Q68D91 Acyl-coenzyme A thioesterase MBLAC2; Acyl-CoA thioesterase MBLAC2; Beta-lactamase MBLAC2; Metallo-beta-lactamase domain-containing protein 2; Palmitoyl-coenzyme A thioesterase MBLAC2; EC 3.1.2.2; EC 3.5.2.6 from Homo sapiens (Human) (see 3 papers)
27% identity, 88% coverage: 14:202/214 of query aligns to 28:239/279 of Q68D91
Sites not aligning to the query:
2gcuA X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
30% identity, 86% coverage: 24:206/214 of query aligns to 28:201/244 of 2gcuA
8ewoA Crystal structure of putative glyoxylase ii from pseudomonas aeruginosa
36% identity, 69% coverage: 14:160/214 of query aligns to 12:142/259 of 8ewoA
Sites not aligning to the query:
5ve5A Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (c314s) from burkholderia phytofirmans in complex with glutathione (see paper)
27% identity, 89% coverage: 23:212/214 of query aligns to 26:200/350 of 5ve5A
Sites not aligning to the query:
Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
30% identity, 86% coverage: 24:206/214 of query aligns to 77:250/294 of Q9C8L4
4chlB Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
27% identity, 87% coverage: 21:206/214 of query aligns to 27:197/237 of 4chlB
O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 4 papers)
27% identity, 87% coverage: 21:206/214 of query aligns to 43:213/254 of O95571
Sites not aligning to the query:
2q42A Ensemble refinement of the protein crystal structure of glyoxalase ii from arabidopsis thaliana gene at2g31350 (see paper)
30% identity, 75% coverage: 1:160/214 of query aligns to 1:140/254 of 2q42A
Sites not aligning to the query:
Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
32% identity, 67% coverage: 17:160/214 of query aligns to 86:210/324 of Q9SID3
Sites not aligning to the query:
2p18A Crystal structure of the leishmania infantum glyoxalase ii (see paper)
28% identity, 92% coverage: 3:198/214 of query aligns to 13:206/283 of 2p18A
>5209816 FitnessBrowser__PV4:5209816
MKYQIVPVTPFQQNCSIIWCEKTKQAAVVDPGGDIERIQQQLAHHGLTLEKILLTHGHID
HVGGAKALADAAGVPIIGPHKDDAFWLETLPQQSKHFGFLPVAAFEPAQYLISGDRVTVG
EQTLEVLHCPGHTPGHIVFYSEADKLAWVGDVLFKGSIGRTDFPQSSHTDLINSITQVLW
PLGREVSFIPGHGPISTFGAERQQNPFVADQLLN
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory