Comparing 5209946 FitnessBrowser__PV4:5209946 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
Q8ZND6 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.222; EC 2.3.1.8 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
68% identity, 100% coverage: 1:711/712 of query aligns to 1:711/714 of Q8ZND6
1xcoD Crystal structure of a phosphotransacetylase from bacillus subtilis in complex with acetylphosphate (see paper)
47% identity, 43% coverage: 406:709/712 of query aligns to 21:324/325 of 1xcoD
2af3C Phosphotransacetylase from methanosarcina thermophila soaked with coenzyme a (see paper)
42% identity, 45% coverage: 391:710/712 of query aligns to 3:328/332 of 2af3C
P38503 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.8 from Methanosarcina thermophila (see 2 papers)
42% identity, 45% coverage: 391:710/712 of query aligns to 4:329/333 of P38503
Sites not aligning to the query:
6ioxA Crystal structure of porphyromonas gingivalis phosphotransacetylase in complex with acetyl-coa (see paper)
45% identity, 43% coverage: 406:709/712 of query aligns to 22:334/339 of 6ioxA
6zngF Maeb full-length acetyl-coa bound state (see paper)
36% identity, 43% coverage: 406:709/712 of query aligns to 440:743/753 of 6zngF
Sites not aligning to the query:
7t85A Crystal structure of the n-terminal domain of the phosphate acetyltransferase from escherichia coli
45% identity, 27% coverage: 1:193/712 of query aligns to 1:160/173 of 7t85A
P76558 NADP-dependent malic enzyme; NADP-ME; EC 1.1.1.40 from Escherichia coli (strain K12) (see paper)
30% identity, 45% coverage: 391:709/712 of query aligns to 430:754/759 of P76558
Sites not aligning to the query:
3u9eB The crystal structure of a possible phosphate acetyl/butaryl transferase (from listeria monocytogenes egd-e) in complex with coa.
26% identity, 20% coverage: 549:691/712 of query aligns to 129:268/288 of 3u9eB
Sites not aligning to the query:
3uf6A The crystal structure of a possible phosphate acetyl/butaryl transferase (from listeria monocytogenes egd-e) in complex with cod (3'-dephosphocoenzyme a)
26% identity, 20% coverage: 549:691/712 of query aligns to 127:266/285 of 3uf6A
Sites not aligning to the query:
>5209946 FitnessBrowser__PV4:5209946
MSRNIMLIPNGTGVGLTSISLGMVRALERHGVKVRFFKPIAQQRPTDKGPERSTTILSKS
PTVNPLEPFDMAHAEHLIRTDQTDVLMEQIIARATECADPSETLIVEGLVQTRNHPFSDD
INYEIAKALDADIIFVAAPGNETPTALMNRLEIAHNAWGGSKNKRLIGAIINKIGAPVDD
EGRARPDLSEVFDHQDVQRPDAASMFQLPGKSKLRILGSVPYNLNLVAPRASDLAKHLSA
RIINAGEMNTRRLRKVTFCARSIPNMVTHIKTDSLLVTSGDRSDVIVSACLAAMNGVKVG
ALLLTGSYEPEPEIMALCEQAFETGLPVFLIDTNTWQTSLNIQRFDHEVPVDDAVRIEEV
QEYVASHIDQSWVESVTMNSPREHRLSPPAFRYKLTELARAAAKTVVLPEGDEPRTIEAA
AICAERGIARCVLIGNPEEIQRIASQQGVTLGEGVEIIEPETARERYVAPMVELRRHKGM
TEVVAREQLEDNMVLGTMMLAQGEVDGIVSGAVNTTANTIRPPLQLIKTAPGSSLVSSIF
FMLMPDQVLVYGDCAINPDPNAEQLADIAIQSADSAAAFGIEPKVAMISYSTGSSGTGSD
VDKVREATRIAKEKRPELVIDGPLQYDAAVMPNVAQSKAPNSPVAGQATVFVFPDLNTGN
TTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQASQN
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory