Comparing 5210587 FitnessBrowser__PV4:5210587 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
7wxiA Gpr domain of drosophila p5cs filament with glutamate and atpgammas (see paper)
33% identity, 98% coverage: 4:409/415 of query aligns to 2:406/430 of 7wxiA
7wxgA Gpr domain closed form of drosophila p5cs filament with glutamate, atp, and NADPH (see paper)
33% identity, 98% coverage: 4:409/415 of query aligns to 2:406/430 of 7wxgA
4jbeB 1.95 angstrom crystal structure of gamma-glutamyl phosphate reductase from saccharomonospora viridis.
32% identity, 97% coverage: 4:407/415 of query aligns to 8:407/412 of 4jbeB
5j7iB Crystal structure of a geobacillus thermoglucosidasius acetylating aldehyde dehydrogenase in complex with adp (see paper)
24% identity, 73% coverage: 94:396/415 of query aligns to 95:426/456 of 5j7iB
5j7iC Crystal structure of a geobacillus thermoglucosidasius acetylating aldehyde dehydrogenase in complex with adp (see paper)
24% identity, 73% coverage: 94:396/415 of query aligns to 94:425/455 of 5j7iC
P0A9Q7 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli (strain K12) (see 8 papers)
25% identity, 63% coverage: 113:374/415 of query aligns to 103:404/891 of P0A9Q7
Sites not aligning to the query:
P0A9Q8 Bifunctional aldehyde-alcohol dehydrogenase AdhE; Alcohol dehydrogenase E; EC 1.2.1.10; EC 1.1.1.1 from Escherichia coli O157:H7 (see paper)
25% identity, 63% coverage: 113:374/415 of query aligns to 103:404/891 of P0A9Q8
Sites not aligning to the query:
7bvpA Adhe spirosome in extended conformation (see paper)
25% identity, 63% coverage: 113:374/415 of query aligns to 103:404/869 of 7bvpA
Sites not aligning to the query:
6tqmA Escherichia coli adhe structure in its compact conformation (see paper)
25% identity, 63% coverage: 113:374/415 of query aligns to 103:404/869 of 6tqmA
Sites not aligning to the query:
8cekA Succinyl-coa reductase from clostridium kluyveri (sucd) with NADPH (see paper)
27% identity, 39% coverage: 113:273/415 of query aligns to 97:256/449 of 8cekA
Sites not aligning to the query:
8cejC Succinyl-coa reductase from clostridium kluyveri (sucd) with mesaconyl-c1-coa (see paper)
27% identity, 39% coverage: 113:273/415 of query aligns to 97:256/449 of 8cejC
Sites not aligning to the query:
8cejA Succinyl-coa reductase from clostridium kluyveri (sucd) with mesaconyl-c1-coa (see paper)
27% identity, 39% coverage: 113:273/415 of query aligns to 97:256/449 of 8cejA
Sites not aligning to the query:
>5210587 FitnessBrowser__PV4:5210587
MSIIETLSRDAAQAAKTLAQVDTQTKNTILLDMARSLRDNSFEIRSANLIDLASAEQAGL
SHAMIDRLTLDGDRIEAMAHGIEIIATLPDPIGVQRDLSTRPNGLAISKMRVPLGVVCMI
YEARPNVTADAGALCFKSGNAVILRGGKEALHTSKVIASVLQKVLKQYGLPASLIAVVPD
PDRALLMELMQQRDTIDVIIPRGGEGLINFVTEHSKVPVIQHFKGVCHLYVDKDADLDKA
LALLLNGKTQRTGVCNALEGLLVHSEVAPKFLAMAATALAKHQVKINCCANTQQYFAAAQ
VLSDEEFGQEYLDLELAVRQVKDFDQAVAHIHRFGSRHTEVICTENELTAKRFQRTVDAS
VVMVNASSRFSDGGELGLGAEIGIATTKLHAYGPMGLESLTTEKYLVNGDGQIRA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory