SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing 59 a.a. (MAKLEITLKR...) to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 20 (the maximum) hits to proteins with known functional sites (download)

7aqcZ Structure of the bacterial rqc complex (decoding state) (see paper)
100% identity, 98% coverage: 2:59/59 of query aligns to 1:58/58 of 7aqcZ

query
sites
7aqcZ

A

A

K

K

L

L

E

E

I

I

T

T

L

L

K

K

R
|
R

S
|
S

V

V

I
|
I

G
|
G

R
|
R

P
|
P

E
|
E

D

D

Q

Q

R

R

V
|
V

T

T

V

V

R
|
R

T
|
T

L

L

G

G

L

L

K
|
K

K
|
K

T
|
T

N

N

Q

Q

T

T

V

V

V

V

H

H

E

E

D

D

N

N

A

A

A
|
A

I

I

R

R

G
|
G

M
|
M

I

I

N

N

K

K

V

V

S

S

H

H

L

L

V

V

S

S

V

V

K

K

E

E

Q

Q

binding : R9 (= R10), S10 (= S11), I12 (= I13), G13 (= G14), R14 (= R15), P15 (= P16), E16 (= E17), V20 (= V21), R23 (= R24), T24 (= T25), K28 (= K29), K29 (= K30), T30 (= T31), A41 (= A42), G44 (= G45), M45 (= M46)

8a573 Cryo-em structure of hflxr bound to the listeria monocytogenes 50s ribosomal subunit. (see paper)
77% identity, 95% coverage: 3:58/59 of query aligns to 1:56/56 of 8a573

query
sites
8a573

K

K

L

L

E

E

I

I

T

T

L

L

K

K

R
|
R

S
|
S

V

L

I
|
I

G
|
G

R
|
R

P

P

E

Q

D

P

Q
|
Q

R

R

V
x
K

T
|
T

V

V

R

Q

T
x
A

L

L

G

G

L

L

K

G

K
|
K

T
|
T

N
|
N

Q

S

T

V

V

V

V

V

H
x
K

E

E

D

D

N
|
N

A
x
P

A
|
A

I

I

R

R

G
|
G

M
|
M

I

I

N

T

K

K

V

V

S

S

H
|
H

L

L

V

V

S

D

V

V

K

K

E

E

binding : R8 (= R10), S9 (= S11), I11 (= I13), G12 (= G14), R13 (= R15), R13 (= R15), Q17 (= Q19), K19 (≠ V21), T20 (= T22), A23 (≠ T25), K28 (= K30), T29 (= T31), N30 (= N32), K35 (≠ H37), N38 (= N40), P39 (≠ A41), A40 (= A42), G43 (= G45), M44 (= M46), H50 (= H52)

7asmX Staphylococcus aureus 50s after 30 minutes incubation at 37c
74% identity, 98% coverage: 2:59/59 of query aligns to 1:58/58 of 7asmX

query
sites
7asmX

A

A

K

K

L

L

E

Q

I

I

T

T

L

L

K

T

R

R

S
|
S

V

V

I
|
I

G
|
G

R
|
R

P

P

E
|
E

D

T

Q

Q

R

R

V

K

T

T

V

V

R

E

T
x
A

L

L

G

G

L

L

K

K

K
|
K

T
|
T

N
|
N

Q

S

T

S

V

V

V

V

H

V

E

E

D

D

N
|
N

A

P

A
|
A

I

I

R

R

G
|
G

M
x
Q

I

I

N

N

K
|
K

V

V

S

K

H

H

L

L

V

V

S

T

V

V

K

E

E

E

Q

K

binding : S10 (= S11), I12 (= I13), G13 (= G14), R14 (= R15), E16 (= E17), A24 (≠ T25), K29 (= K30), T30 (= T31), N31 (= N32), N39 (= N40), A41 (= A42), G44 (= G45), Q45 (≠ M46), K48 (= K49)

6o8w0 30S ribosomal protein S10 (see paper)
63% identity, 97% coverage: 2:58/59 of query aligns to 1:57/58 of 6o8w0

query
sites
6o8w0

A

A

K

E

L

L

E

K

I

I

T

T

L

L

K

K

R
|
R

S
|
S

V

V

I
|
I

G
|
G

R

R

P

P

E

Q

D

N

Q

Q

R

R

V

A

T
|
T

V

V

R

K

T
x
A

L

L

G

G

L

L

K

G

K
|
K

T

V

N

N

Q

S

T

T

V

V

V

T

H
x
K

E

P

D

A

N
|
N

A
x
E

A
|
A

I

I

R

K

G
|
G

M
|
M

I

V

N

N

K

T

V

I

S

S

H

H

L

L

V

V

S

D

V

V

K

E

E

E

binding : R9 (= R10), S10 (= S11), I12 (= I13), G13 (= G14), T21 (= T22), A24 (≠ T25), K29 (= K30), K36 (≠ H37), N39 (= N40), E40 (≠ A41), A41 (= A42), G44 (= G45), M45 (= M46)

5zeb1 50S ribosomal protein L33 1 (see paper)
60% identity, 97% coverage: 2:58/59 of query aligns to 1:57/60 of 5zeb1

query
sites
5zeb1

A

A

K

E

L

L

E

K

I

I

T

T

L

Q

K

V

R
|
R

S
|
S

V

T

I
|
I

G
|
G

R

A

P
x
R

E
x
W

D
x
K

Q

Q

R
|
R

V
x
E

T
x
S

V

L

R
|
R

T
|
T

L

L

G

G

L

L

K

K

K

K

T
x
I

N
x
R

Q

Q

T

S

V

V

V

V

H
x
R

E

E

D

D

N

N

A

A

A
x
Q

I

T

R

R

G

G

M
x
L

I

I

N

N

K

T

V

V

S

H

H
|
H

L

L

V

V

S

E

V

V

K

E

E

E

binding : R9 (= R10), S10 (= S11), I12 (= I13), G13 (= G14), R15 (≠ P16), R15 (≠ P16), W16 (≠ E17), K17 (≠ D18), R19 (= R20), E20 (≠ V21), S21 (≠ T22), R23 (= R24), T24 (= T25), I30 (≠ T31), R31 (≠ N32), R36 (≠ H37), Q41 (≠ A42), L45 (≠ M46), H51 (= H52)

5myjB2 of 70S ribosome from Lactococcus lactis (see paper)
54% identity, 97% coverage: 2:58/59 of query aligns to 1:57/58 of 5myjB2

query
sites
5myjB2

A

A

K

Q

L

I

E

K

I

I

T

T

L

L

K

V

R
x
N

S
|
S

V

P

I
|
I

G

G

R

R

P

I

E
x
P

D

A

Q

Q

R

R

V
x
K

T
|
T

V

V

R

K

T

A

L

L

G

G

L

L

K

G

K
|
K

T
x
L

N

N

Q

S

T

S

V

V

V

V

H

K

E
|
E

D

G

N

S

A

P

A
|
A

I
|
I

R

L

G
|
G

M
|
M

I

V

N

N

K
x
S

V

I

S

S

H

H

L

L

V

V

S

K

V

V

K

E

E

E

binding : N9 (≠ R10), S10 (= S11), I12 (= I13), P16 (≠ E17), K20 (≠ V21), T21 (= T22), K29 (= K30), L30 (≠ T31), E37 (= E38), A41 (= A42), I42 (= I43), G44 (= G45), M45 (= M46), S48 (≠ K49)

6b4vAA blasticidin S and E. coli release factor 1 bound to the 70S ribosome (see paper)
46% identity, 97% coverage: 1:57/59 of query aligns to 1:57/60 of 6b4vAA

query
sites
6b4vAA

M

M

A

P

K

R

L

L

E

K

I

V

T

K

L

L

K

V

R
x
K

S
|
S

V

P

I
|
I

G
|
G

R
x
Y

P
|
P

E
x
K

D

D

Q
|
Q

R
x
K

V
x
A

T
x
A

V

L

R
x
K

T
x
A

L

L

G

G

L

L

K

R

K
x
R

T
x
L

N

Q

Q

Q

T

E

V

R

V

V

H

L

E

E

D

D

N

T

A
x
P

A
|
A

I

I

R

R

G
|
G

M
x
N

I

V

N

E

K
|
K

V

V

S

A

H
|
H

L

L

V

V

S

R

V

V

K

E

binding : K10 (≠ R10), S11 (= S11), I13 (= I13), G14 (= G14), Y15 (≠ R15), P16 (= P16), K17 (≠ E17), Q19 (= Q19), K20 (≠ R20), A21 (≠ V21), A22 (≠ T22), K24 (≠ R24), A25 (≠ T25), R30 (≠ K30), L31 (≠ T31), P41 (≠ A41), A42 (= A42), G45 (= G45), N46 (≠ M46), K49 (= K49), H52 (= H52)

7f0dZ Cryo-em structure of mycobacterium tuberculosis 50s ribosome subunit bound with clarithromycin (see paper)
50% identity, 95% coverage: 2:57/59 of query aligns to 1:56/59 of 7f0dZ

query
sites
7f0dZ

A

S

K

Q

L

L

E

K

I

I

T

T

L

Q

K

V

R
|
R

S
|
S

V

T

I
|
I

G

G

R

A

P
x
R

E
x
W

D
x
K

Q
|
Q

R

R

V
x
E

T
x
S

V

L

R
|
R

T
|
T

L

L

G

G

L

L

K
x
R

K
x
R

T

I

N
x
R

Q

H

T

S

V

V

V

I

H

R

E

E

D

D

N

N

A

A

A
|
A

I

T

R

R

G
|
G

M
x
L

I

I

N

A

K

V

V

V

S
x
R

H
|
H

L

L

V

V

S

E

V

V

K

E

binding : R9 (= R10), S10 (= S11), I12 (= I13), R15 (≠ P16), R15 (≠ P16), W16 (≠ E17), K17 (≠ D18), Q18 (= Q19), E20 (≠ V21), S21 (≠ T22), R23 (= R24), T24 (= T25), R28 (≠ K29), R29 (≠ K30), R31 (≠ N32), A41 (= A42), G44 (= G45), L45 (≠ M46), R50 (≠ S51), H51 (= H52)

7jilZ 50S ribosomal protein L15 (see paper)
54% identity, 95% coverage: 3:58/59 of query aligns to 1:56/56 of 7jilZ

query
sites
7jilZ

K

K

L

L

E

L

I

V

T

K

L

Q

K

V

R
|
R

S
|
S

V

K

I
|
I

G
x
N

R
x
C

P
|
P

E
x
L

D

S

Q
|
Q

R

K

V
x
R

T

G

V

L

R

E

T
x
A

L

L

G

G

L

L

K

R

K

K

T

L

N

G

Q

Q

T

V

V

V

V

E

H
|
H

E

E

D

S

N

N

A

P

A

A

I

I

R

L

G
|
G

M
|
M

I

I

N

N

K
|
K

V

V

S

K

H
|
H

L

L

V

V

S

S

V

V

K

E

E

E

binding : R8 (= R10), S9 (= S11), I11 (= I13), N12 (≠ G14), C13 (≠ R15), P14 (= P16), L15 (≠ E17), Q17 (= Q19), R19 (≠ V21), A23 (≠ T25), H35 (= H37), G43 (= G45), M44 (= M46), K47 (= K49), H50 (= H52)

1vy4D3 50S ribosomal protein L36 (see paper)
45% identity, 95% coverage: 2:57/59 of query aligns to 1:56/59 of 1vy4D3

query
sites
1vy4D3

A

P

K

R

L

L

E

K

I

V

T

K

L

L

K

V

R
x
K

S
|
S

V

P

I
|
I

G
|
G

R
x
Y

P
|
P

E
x
K

D

D

Q
|
Q

R
x
K

V
x
A

T

A

V

L

R
x
K

T
x
A

L

L

G

G

L

L

K
x
R

K
x
R

T
x
L

N
x
Q

Q

Q

T

E

V

R

V

V

H

L

E

E

D

D

N

T

A
x
P

A
|
A

I

I

R

R

G
|
G

M
x
N

I

V

N

E

K
|
K

V

V

S

A

H
|
H

L

L

V

V

S

R

V

V

K

E

binding magnesium ion: K9 (≠ R10), S10 (= S11)
binding : K9 (≠ R10), S10 (= S11), I12 (= I13), G13 (= G14), Y14 (≠ R15), Y14 (≠ R15), P15 (= P16), K16 (≠ E17), Q18 (= Q19), K19 (≠ R20), A20 (≠ V21), K23 (≠ R24), A24 (≠ T25), R28 (≠ K29), R29 (≠ K30), L30 (≠ T31), Q31 (≠ N32), P40 (≠ A41), A41 (= A42), G44 (= G45), N45 (≠ M46), K48 (= K49), H51 (= H52)

8a3ly 50S ribosomal protein L36 (see paper)
49% identity, 93% coverage: 4:58/59 of query aligns to 4:58/58 of 8a3ly

query
sites
8a3ly

L

I

E

K

I

I

T

T

L

Q

K

T

R
|
R

S
|
S

V

A

I
|
I

G
|
G

R

R

P

L

E
x
P

D
x
K

Q
x
H

R

K

V
x
A

T
|
T

V

L

R
x
L

T
x
G

L

L

G

G

L

L

K
x
R

K
x
R

T
x
I

N

G

Q

H

T

T

V

V

V

E

H
x
R

E
|
E

D

D

N

T

A

P

A
|
A

I

I

R

R

G
|
G

M
|
M

I

I

N

N

K

A

V

V

S

S

H
x
F

L

M

V

V

S

K

V

V

K

E

E

E

binding : R10 (= R10), S11 (= S11), I13 (= I13), G14 (= G14), P17 (≠ E17), K18 (≠ D18), H19 (≠ Q19), A21 (≠ V21), T22 (= T22), L24 (≠ R24), G25 (≠ T25), R29 (≠ K29), R30 (≠ K30), I31 (≠ T31), R37 (≠ H37), E38 (= E38), A42 (= A42), G45 (= G45), M46 (= M46), F52 (≠ H52)

9c4gy Cutibacterium acnes 50s ribosomal subunit with clindamycin bound (see paper)
45% identity, 98% coverage: 1:58/59 of query aligns to 1:58/58 of 9c4gy

query
sites
9c4gy

M

M

A

S

K

K

L

L

E

K

I

I

T

T

L

Q

K

I

R
x
K

S
|
S

V

G

I
|
I

G
x
A

R

T

P
x
K

E
x
P

D
x
N

Q

H

R

R

V
x
E

T
|
T

V

L

R
|
R

T
x
S

L

L

G

G

L

L

K
|
K

K

R

T
x
I

N

G

Q

D

T

T

V

V

V

I

H
x
K

E

E

D

D

N
x
R

A
x
P

A
x
E

I
x
F

R

R

G
|
G

M
|
M

I

V

N

R

K

T

V

V

S
x
R

H
|
H

L

L

V

V

S

T

V

M

K

E

E

E

binding : K10 (≠ R10), S11 (= S11), I13 (= I13), A14 (≠ G14), K16 (≠ P16), P17 (≠ E17), N18 (≠ D18), E21 (≠ V21), T22 (= T22), R24 (= R24), S25 (≠ T25), K29 (= K29), I31 (≠ T31), K37 (≠ H37), R40 (≠ N40), P41 (≠ A41), E42 (≠ A42), F43 (≠ I43), G45 (= G45), M46 (= M46), R51 (≠ S51), H52 (= H52)

7a0rW 50s deinococcus radiodurans ribosome bounded with mycinamicin i (see paper)
47% identity, 93% coverage: 4:58/59 of query aligns to 1:55/55 of 7a0rW

query
sites
7a0rW

L

M

E

K

I

I

T

K

L

L

K

V

R
|
R

S
|
S

V

V

I
|
I

G
|
G

R
|
R

P

P

E

G

D

N

Q
|
Q

R

V

V
x
K

T
|
T

V

V

R
x
Q

T
x
A

L

L

G

G

L

L

K

R

K

K

T
x
I

N

G

Q

D

T

S

V

R

V

E

H

V

E
x
S

D

D

N
x
T

A

P

A
|
A

I

V

R

R

G
|
G

M
|
M

I

V

N

K

K
x
T

V

V

S

K

H
|
H

L

L

V

L

S

E

V

V

K

Q

E

E

binding : R7 (= R10), S8 (= S11), I10 (= I13), G11 (= G14), R12 (= R15), Q16 (= Q19), K18 (≠ V21), T19 (= T22), Q21 (≠ R24), A22 (≠ T25), I28 (≠ T31), S35 (≠ E38), T37 (≠ N40), A39 (= A42), G42 (= G45), M43 (= M46), T46 (≠ K49), H49 (= H52)

5wdtZ 30S ribosomal protein S20 (see paper)
48% identity, 92% coverage: 4:57/59 of query aligns to 3:56/56 of 5wdtZ

query
sites
5wdtZ

L

I

E

K

I

I

T

T

L

Q

K

T

R

R

S
|
S

V

A

I
|
I

G

G

R

R

P
x
L

E

P

D
x
K

Q

H

R

K

V
x
A

T

T

V

L

R

L

T
x
G

L

L

G
|
G

L

L

K
x
R

K

R

T
x
I

N
x
G

Q

H

T
|
T

V

V

V

E

H
x
R

E

E

D

D

N

T

A

P

A
|
A

I

I

R

R

G
|
G

M
|
M

I

I

N

N

K

A

V

V

S

S

H
x
F

L

M

V

V

S

K

V

V

K

E

binding magnesium ion: G31 (≠ N32), T33 (= T34)
binding : S10 (= S11), I12 (= I13), L15 (≠ P16), K17 (≠ D18), A20 (≠ V21), G24 (≠ T25), G26 (= G27), R28 (≠ K29), I30 (≠ T31), R36 (≠ H37), A41 (= A42), G44 (= G45), M45 (= M46), F51 (≠ H52)

7pktx mL119 (see paper)
43% identity, 92% coverage: 4:57/59 of query aligns to 6:59/167 of 7pktx

query
sites
7pktx

L

L

E

F

I

V

T

T

L

L

K

R

R
|
R

S
x
G

V

F

I
x
A

G
|
G

R
x
T

P
|
P

E
x
W

D

F

Q
x
H

R

R

V
x
R

T

V

V

L

R

E

T
x
S

L

L

G

G

L

L

K

K

K
x
Y

T
x
R

N
x
H

Q

Q

T

C

V

V

V

E

H
x
K

E
x
P

D

N

N

N

A
x
S

A
x
S

I

I

R

R

G
|
G

M
|
M

I

L

N

S

K

K

V

V

S

P

H
|
H

L

L

V

V

S

V

V

I

K

E

binding : R12 (= R10), G13 (≠ S11), A15 (≠ I13), G16 (= G14), T17 (≠ R15), P18 (= P16), W19 (≠ E17), H21 (≠ Q19), R23 (≠ V21), S27 (≠ T25), Y32 (≠ K30), R33 (≠ T31), R33 (≠ T31), H34 (≠ N32), K39 (≠ H37), P40 (≠ E38), S43 (≠ A41), S44 (≠ A42), G47 (= G45), M48 (= M46), M48 (= M46), H54 (= H52)

Sites not aligning to the query:

binding : 92, 94, 95, 111, 118, 119, 120, 122, 124, 125, 129, 131, 132, 133, 137, 138, 140, 145, 146, 148, 149, 149, 156, 157, 158, 160, 161, 161, 162, 167

6xywAz At4g35490 (see paper)
39% identity, 95% coverage: 4:59/59 of query aligns to 3:58/82 of 6xywAz

query
sites
6xywAz

L

L

E

Y

I

I

T

T

L

L

K

V

R
|
R

S
x
G

V

L

I
x
P

G

G

R
x
T

P
x
R

E
x
K

D

L

Q
x
H

R
|
R

V

R

T
|
T

V

L

R

E

T
x
A

L

M

G

G

L

L

K

R

K

R

T
x
C

N
x
H

Q
x
R

T
|
T

V

V

V

L

H

H

E

S

D

N

N
|
N

A
x
S

A
x
S

I

I

R

R

G
|
G

M
|
M

I

I

N

D

K

Q

V

V

S

K

H
x
R

L

M

V

V

S

V

V

V

K

E

E

T

Q

E

binding : R9 (= R10), G10 (≠ S11), P12 (≠ I13), T14 (≠ R15), R15 (≠ P16), R15 (≠ P16), K16 (≠ E17), H18 (≠ Q19), R19 (= R20), T21 (= T22), A24 (≠ T25), C30 (≠ T31), H31 (≠ N32), R32 (≠ Q33), T33 (= T34), N39 (= N40), S40 (≠ A41), S41 (≠ A42), G44 (= G45), M45 (= M46), R51 (≠ H52)

6yweU structure of the mitoribosome from Neurospora crassa in the P/E tRNA bound state (see paper)
44% identity, 93% coverage: 4:58/59 of query aligns to 3:57/138 of 6yweU

query
sites
6yweU

L

F

E

R

I

I

T

T

L

L

K

H

R
|
R

S
|
S

V

A

I
|
I

G
|
G

R

L

P

P

E
x
K

D
x
R

Q

T

R

H

V
x
G

T
x
V

V

L

R
x
A

T
x
A

L

L

G

G

L
|
L

K
x
R

K
x
R

T
x
R

N
|
N

Q

Q

T

T

V

V

V

F

H

H

E

P

D

V

N

E

A
x
P

A
x
Q

I
x
F

R

A

G
|
G

M

M

I

L

N

M

K

K

V

V

S

K

H

E

L

L

V

V

S

R

V

V

K

E

E

E

binding : R9 (= R10), S10 (= S11), I12 (= I13), G13 (= G14), K16 (≠ E17), R17 (≠ D18), G20 (≠ V21), V21 (≠ T22), A23 (≠ R24), A24 (≠ T25), L27 (= L28), R28 (≠ K29), R29 (≠ K30), R30 (≠ T31), N31 (= N32), P40 (≠ A41), Q41 (≠ A42), F42 (≠ I43), G44 (= G45)

Sites not aligning to the query:

binding : 64, 65, 69, 71, 72, 73

8cd1Z phikz014 (see paper)
39% identity, 95% coverage: 2:57/59 of query aligns to 1:56/57 of 8cd1Z

query
sites
8cd1Z

A

A

K

T

L

V

E

K

I

V

T

T

L

L

K

V

R
x
K

S
|
S

V

L

I
x
N

G

G

R
|
R

P

L

E

A

D
x
N

Q

H

R

K

V

A

T
x
C

V

V

R

K

T
x
G

L

L

G

G

L

L

K
x
R

K
x
R

T
x
I

N
|
N

Q

H

T

T

V

V

V

E

H

V

E

Q

D

D

N

T

A
x
P

A
x
E

I

N

R

R

G
|
G

M
|
M

I

I

N

N

K

K

V

A

S
x
Y

H
x
Y

L

L

V

L

S

R

V

V

K

E

binding : K9 (≠ R10), S10 (= S11), N12 (≠ I13), R14 (= R15), N17 (≠ D18), C21 (≠ T22), G24 (≠ T25), R28 (≠ K29), R29 (≠ K30), I30 (≠ T31), N31 (= N32), P40 (≠ A41), E41 (≠ A42), G44 (= G45), M45 (= M46), Y50 (≠ S51), Y51 (≠ H52)

7m4xY 30S ribosomal protein S7 (see paper)
36% identity, 98% coverage: 1:58/59 of query aligns to 1:58/58 of 7m4xY

query
sites
7m4xY

M

M

A

K

K

T

L

I

E

K

I

V

T

T

L

Q

K

T

R
x
K

S
|
S

V

S

I

S

G
x
H

R

R

P

L

E

K

D
x
N

Q

H

R

K

V
x
L

T
x
C

V

L

R
x
Q

T
x
G

L

L

G

G

L

L

K
x
R

K

R

T
x
I

N

G

Q

H

T

T

V

V

V

E

H

V

E

Q

D

D

N

T

A

P

A
x
S

I

N

R

R

G

G

M
|
M

I

I

N

N

K
|
K

V

V

S

Y

H

Y

L

M

V

V

S

S

V

V

K

E

E

E

binding : K10 (≠ R10), S11 (= S11), H14 (≠ G14), N18 (≠ D18), L21 (≠ V21), C22 (≠ T22), Q24 (≠ R24), G25 (≠ T25), R29 (≠ K29), I31 (≠ T31), S42 (≠ A42), M46 (= M46), K49 (= K49)

8rd8YW Small ribosomal subunit protein uS5 (see paper)
36% identity, 90% coverage: 4:56/59 of query aligns to 3:55/56 of 8rd8YW

query
sites
8rd8YW

L

M

E

K

I

V

T

T

L

Q

K

L

R

K

S
|
S

V

G

I

A

G
x
H

R

R

P

L

E

K

D

S

Q
x
H

R

K

V
x
A

T
x
S

V

L

R
x
K

T
x
G

L

L

G
|
G

L

L

K
x
R

K

R

T
x
I

N
|
N

Q

H

T

S

V

V

V

V

H

V

E
|
E

D

D

N

T

A

P

A
x
S

I

T

R

R

G
|
G

M
|
M

I

V

N

N

K
x
R

V

V

S

N

H
x
Y

L

L

V

V

S

K

V

V

binding : S10 (= S11), H13 (≠ G14), H18 (≠ Q19), A20 (≠ V21), S21 (≠ T22), K23 (≠ R24), G24 (≠ T25), G26 (= G27), R28 (≠ K29), I30 (≠ T31), N31 (= N32), E37 (= E38), S41 (≠ A42), G44 (= G45), M45 (= M46), R48 (≠ K49), Y51 (≠ H52)

Query Sequence

>59 a.a. (MAKLEITLKR...)
MAKLEITLKRSVIGRPEDQRVTVRTLGLKKTNQTVVHEDNAAIRGMINKVSHLVSVKEQ

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory