Comparing 6936757 FitnessBrowser__SB2B:6936757 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 7 hits to proteins with known functional sites (download)
2e2oA Crystal structure of sulfolobus tokodaii hexokinase in complex with glucose (see paper)
28% identity, 94% coverage: 11:294/301 of query aligns to 3:288/299 of 2e2oA
2e2qA Crystal structure of sulfolobus tokodaii hexokinase in complex with xylose, mg2+, and adp (see paper)
28% identity, 94% coverage: 11:294/301 of query aligns to 3:288/297 of 2e2qA
2e2pA Crystal structure of sulfolobus tokodaii hexokinase in complex with adp (see paper)
28% identity, 94% coverage: 11:294/301 of query aligns to 3:288/298 of 2e2pA
2ch6A Crystal structure of human n-acetylglucosamine kinase in complex with adp and glucose (see paper)
27% identity, 74% coverage: 11:234/301 of query aligns to 3:236/343 of 2ch6A
Sites not aligning to the query:
Q9UJ70 N-acetyl-D-glucosamine kinase; N-acetylglucosamine kinase; GlcNAc kinase; Muramyl dipeptide kinase; N-acetyl-D-mannosamine kinase; EC 2.7.1.59; EC 2.7.1.-; EC 2.7.1.60 from Homo sapiens (Human) (see 5 papers)
27% identity, 74% coverage: 11:234/301 of query aligns to 4:237/344 of Q9UJ70
Sites not aligning to the query:
P81799 N-acetyl-D-glucosamine kinase; N-acetylglucosamine kinase; GlcNAc kinase; Muramyl dipeptide kinase; N-acetyl-D-mannosamine kinase; EC 2.7.1.59; EC 2.7.1.-; EC 2.7.1.60 from Rattus norvegicus (Rat) (see paper)
28% identity, 74% coverage: 11:234/301 of query aligns to 4:237/343 of P81799
Sites not aligning to the query:
8ow7A Crystal structure of tannerella forsythia sugar kinase k1058 in complex with n-acetylmuramic acid (murnac) (see paper)
33% identity, 53% coverage: 43:201/301 of query aligns to 32:185/277 of 8ow7A
>6936757 FitnessBrowser__SB2B:6936757
MAFDQTLEGQLYLGIDGGGSKCRATLYNNKLDVLGTGVAGRANPLFGLEQTFESILASTE
MALRDAGLSLNDASLLVAGLGLAGVNVPRLLADVQAWQHPFKTMYVTSDLHTACIGAHQG
GDGAVIITGTGSCGYVHVGDESLSLGGHGFALGDKGSGAWLGLRAAEHVLLQLDGFAEPT
ALTERLFANLGVSDALGIVENLAGRSSSCYATLAREVFAAADEGDKVAVGILREGAAYIS
EMARKLFTLEPARFSMIGGLAEPLQKWLDADVVARLEPSLAAPETGAVLFAIQQHNKQSA
A
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory