SitesBLAST
Comparing 6937023 FitnessBrowser__SB2B:6937023 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
7p7wBBB Ubiquitin-like protein SMT3,N-acetyl-D-glucosamine kinase
39% identity, 92% coverage: 1:308/335 of query aligns to 5:305/306 of 7p7wBBB
- binding adenosine-5'-diphosphate: G135 (= G142), T136 (= T143), G196 (= G200), R197 (≠ T201), E200 (≠ G204), A213 (≠ T216), P214 (≠ Y217), G258 (= G261), G259 (= G262), L260 (≠ I263), N262 (≠ E265)
- binding zinc ion: H161 (= H168), C182 (= C186), C184 (= C188), C189 (= C193)
7p9lAAA Ubiquitin-like protein SMT3,N-acetyl-D-glucosamine kinase
39% identity, 92% coverage: 1:308/335 of query aligns to 2:302/303 of 7p9lAAA
- binding 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose: G10 (= G9), P66 (= P77), G67 (= G78), L77 (= L87), T78 (≠ S88), S79 (= S89), N105 (= N115), D106 (= D116), A107 (≠ C117), I130 (= I140), G132 (= G142), T133 (= T143), G134 (= G144), V135 (≠ L145), G136 (= G146), E155 (= E165), H158 (= H168), D188 (≠ E195)
- binding zinc ion: H158 (= H168), C179 (= C186), C181 (= C188), C186 (= C193), E212 (≠ V218), H216 (≠ D222)
7p9pAAA Ubiquitin-like protein SMT3,N-acetyl-D-glucosamine kinase
39% identity, 92% coverage: 1:308/335 of query aligns to 3:303/304 of 7p9pAAA
- binding phosphoaminophosphonic acid-adenylate ester: G10 (= G8), G11 (= G9), T12 (= T10), K13 (= K11), I131 (= I140), G133 (= G142), T134 (= T143), G194 (= G200), R195 (≠ T201), E198 (≠ G204), A211 (≠ T216), P212 (≠ Y217), I215 (≠ L220), G256 (= G261), G257 (= G262), L258 (≠ I263), N260 (≠ E265)
- binding zinc ion: H159 (= H168), C180 (= C186), C182 (= C188), C187 (= C193), E213 (≠ V218), H217 (≠ D222)
Q8ZPZ9 N-acetyl-D-glucosamine kinase; GlcNAc kinase; EC 2.7.1.59 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
41% identity, 92% coverage: 1:307/335 of query aligns to 1:299/303 of Q8ZPZ9
- H157 (= H168) binding
- C177 (= C186) binding
- C179 (= C188) binding
- C184 (= C193) binding
2ap1A Crystal structure of the putative regulatory protein
41% identity, 92% coverage: 1:307/335 of query aligns to 3:301/305 of 2ap1A
4db3A 1.95 angstrom resolution crystal structure of n-acetyl-d-glucosamine kinase from vibrio vulnificus.
34% identity, 92% coverage: 1:307/335 of query aligns to 9:307/311 of 4db3A
2qm1B Crystal structure of glucokinase from enterococcus faecalis
27% identity, 93% coverage: 4:314/335 of query aligns to 10:325/325 of 2qm1B
3vglA Crystal structure of a rok family glucokinase from streptomyces griseus in complex with glucose and amppnp (see paper)
30% identity, 92% coverage: 1:309/335 of query aligns to 2:310/312 of 3vglA
- binding phosphoaminophosphonic acid-adenylate ester: G9 (= G8), G10 (= G9), T11 (= T10), K12 (= K11), G130 (= G142), T131 (= T143), G180 (= G200), R181 (≠ T201), L183 (= L203), V184 (≠ G204), G214 (vs. gap), K215 (vs. gap), S218 (vs. gap), G259 (= G261), G260 (= G262), V261 (≠ I263), E264 (≠ V266)
- binding beta-D-glucopyranose: A64 (≠ P77), G65 (= G78), Y66 (≠ V79), P78 (= P92), N103 (= N115), D104 (= D116), A105 (≠ C117), G132 (= G144), L133 (= L145), G134 (= G146), E153 (= E165), H156 (= H168), E175 (= E195)
- binding zinc ion: H156 (= H168), C166 (= C186), C168 (= C188), C173 (= C193)
3vgkB Crystal structure of a rok family glucokinase from streptomyces griseus (see paper)
30% identity, 92% coverage: 1:309/335 of query aligns to 2:310/312 of 3vgkB
6jdbA Crystal structure of n-acetyl mannosmaine kinase in complex with mannac-6p and adp from haemophilus influenzae
25% identity, 91% coverage: 5:309/335 of query aligns to 6:286/290 of 6jdbA
- binding adenosine-5'-diphosphate: G9 (= G8), G10 (= G9), T11 (= T10), K12 (= K11), S129 (≠ G142), T130 (= T143), G179 (= G200), P195 (≠ T216), K196 (≠ Y217), S241 (≠ G262), V242 (≠ I263), Q274 (≠ A297)
- binding 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-mannopyranose: G9 (= G8), T62 (≠ P77), G63 (= G78), A72 (≠ S88), L73 (≠ S89), N74 (= N90), N77 (≠ C93), N102 (= N115), D103 (= D116), A104 (≠ C117), S129 (≠ G142), T130 (= T143), G131 (= G144), V132 (≠ L145), G133 (= G146), H152 (≠ E165), H155 (= H168), E174 (= E195)
- binding zinc ion: H155 (= H168), C165 (= C186), C167 (= C188), C172 (= C193)
P32718 D-allose kinase; Allokinase; EC 2.7.1.55 from Escherichia coli (strain K12) (see paper)
28% identity, 91% coverage: 4:308/335 of query aligns to 10:296/309 of P32718
- A73 (= A65) mutation to G: 60-fold increase in catalytic efficiency for glucose phosphorylation. 45-fold increase in D-glucose affinity. No change in catalytic efficiency for D-allose phosphorylation.
- F145 (≠ G147) mutation to L: 10-fold increase in catalytic efficiency for glucose phosphorylation. Slight increase in catalytic efficiency for D-allose phosphorylation.
6jdoA Crystal structure of n-acetyl mannosmaine kinase with amp-pnp from pasteurella multocida
26% identity, 81% coverage: 5:274/335 of query aligns to 6:261/293 of 6jdoA
- binding phosphoaminophosphonic acid-adenylate ester: S130 (≠ G142), T131 (= T143), G180 (= G200), P196 (≠ T216), K197 (≠ Y217), F200 (≠ L220), S242 (vs. gap), V243 (vs. gap), A246 (≠ S264)
- binding calcium ion: H156 (= H168), C168 (= C188), R170 (≠ L190)
6jdhA Crystal structure of n-acetyl mannosmaine kinase from pasteurella multocida
26% identity, 81% coverage: 5:274/335 of query aligns to 6:261/293 of 6jdhA
3vovB Crystal structure of rok hexokinase from thermus thermophilus (see paper)
31% identity, 90% coverage: 4:306/335 of query aligns to 5:289/298 of 3vovB
1z05A Crystal structure of the rok family transcriptional regulator, homolog of e.Coli mlc protein.
26% identity, 73% coverage: 71:316/335 of query aligns to 138:389/396 of 1z05A