Comparing 7026773 Shewana3_3905 N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq) to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
2i3gA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosis in complex with NADP+. (see paper)
33% identity, 98% coverage: 3:322/326 of query aligns to 6:330/347 of 2i3gA
7npjB Crystal structure of mycobacterium tuberculosis argc in complex with 6-phenoxy-3-pyridinamine
33% identity, 98% coverage: 3:322/326 of query aligns to 3:327/344 of 7npjB
7nphC Crystal structure of mycobacterium tuberculosis argc in complex with 5-methoxy-1,3-benzoxazole-2-carboxylic acid
33% identity, 98% coverage: 3:322/326 of query aligns to 3:327/344 of 7nphC
7notA Crystal structure of mycobacterium tuberculosis argc in complex with nicotinamide adenine dinucleotide phosphate (NADP+) and 5-methoxy-3- indoleacetic acid
33% identity, 98% coverage: 3:322/326 of query aligns to 3:327/344 of 7notA
7nnrA Crystal structure of mycobacterium tuberculosis argc in complex with xanthene-9-carboxylic acid
33% identity, 98% coverage: 3:322/326 of query aligns to 3:327/344 of 7nnrA
2ozpA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (ttha1904) from thermus thermophilus
29% identity, 99% coverage: 2:325/326 of query aligns to 2:328/342 of 2ozpA
O50146 [LysW]-L-2-aminoadipate 6-phosphate reductase; EC 1.2.1.103 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
29% identity, 99% coverage: 2:325/326 of query aligns to 4:330/344 of O50146
5einA Crystal structure of c148a mutant of lysy from thermus thermophilus in complex with NADP+ and lysw-gamma-aminoadipic acid (see paper)
27% identity, 99% coverage: 2:325/326 of query aligns to 4:330/344 of 5einA
>7026773 Shewana3_3905 N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq)
MKNIAIIGASGYTGAQLTALVHAESELSIQGLYVSENSLDKGRALADLYPVYSHIDLALS
PLTEEAKAKIVAEADAVVLATEHSVSLHLAAWFYNQGLAVFDLSGAYRFSDVAQYPKWYG
FEHEYPEVLAKAVYGLAEWNAKEVAATKMIAVPGCYPTASLTALKPLKNLLTSAYPVINA
VSGVTGAGRKAQLHTSFCEVSLTPYGVLGHRHQPEIATQLGQEVIFTPHLGNFKRGILAT
ITVQLKPGTTTADVAAAYSVYDQAPLVTVKQNQFPKVDDVVLTPNCHLGWKFDENSGYLV
VASAIDNLMKGAASQALQCIKIHFNL
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory