Comparing 8499797 FitnessBrowser__Miya:8499797 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q07607 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; Protein MosA; EC 4.3.3.7 from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
51% identity, 99% coverage: 3:292/292 of query aligns to 2:291/292 of Q07607
Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
47% identity, 99% coverage: 3:292/292 of query aligns to 2:294/294 of Q9X1K9
1o5kA Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
47% identity, 99% coverage: 3:292/292 of query aligns to 3:295/295 of 1o5kA
4dxvA Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
47% identity, 99% coverage: 3:292/292 of query aligns to 2:291/291 of 4dxvA
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
47% identity, 99% coverage: 3:292/292 of query aligns to 2:291/291 of 3u8gA
3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
47% identity, 99% coverage: 3:292/292 of query aligns to 2:291/291 of 3tdfA
3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
47% identity, 99% coverage: 3:292/292 of query aligns to 2:291/291 of 3tceA
3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
47% identity, 99% coverage: 3:292/292 of query aligns to 2:291/291 of 3rk8A
3pueB Crystal structure of the complex of dhydrodipicolinate synthase from acinetobacter baumannii with lysine at 2.6a resolution
47% identity, 99% coverage: 3:292/292 of query aligns to 2:291/291 of 3pueB
4m19A Dihydrodipicolinate synthase from c. Jejuni with pyruvate bound to the active site and lysine bound to allosteric site (see paper)
47% identity, 98% coverage: 5:291/292 of query aligns to 6:293/296 of 4m19A
6u01B Dihydrodipicolinate synthase (dhdps) from c.Jejuni, n84d mutant with pyruvate bound in the active site (see paper)
47% identity, 98% coverage: 5:291/292 of query aligns to 6:293/296 of 6u01B
7kkdB Dihydrodipicolinate synthase (dhdps) from c.Jejuni, n84a mutant with pyruvate bound in the active site and r,r-bislysine bound at the allosteric site
47% identity, 98% coverage: 5:291/292 of query aligns to 16:303/306 of 7kkdB
7kg2A Dihydrodipicolinate synthase (dhdps) from c.Jejuni, h59k mutant with pyruvate bound in the active site and l-histidine bound at the allosteric site
47% identity, 98% coverage: 5:291/292 of query aligns to 6:293/296 of 7kg2A
4i7wA Agrobacterium tumefaciens dhdps with lysine and pyruvate
48% identity, 99% coverage: 3:292/292 of query aligns to 2:293/294 of 4i7wA
Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
48% identity, 99% coverage: 3:292/292 of query aligns to 2:293/294 of Q8UGL3
2atsA Dihydrodipicolinate synthase co-crystallised with (s)-lysine
45% identity, 99% coverage: 3:292/292 of query aligns to 2:292/292 of 2atsA
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Escherichia coli (strain K12) (see 7 papers)
45% identity, 99% coverage: 3:292/292 of query aligns to 2:292/292 of P0A6L2
5t25A Kinetic, spectral and structural characterization of the slow binding inhibitor acetopyruvate with dihydrodipicolinate synthase from escherichia coli.
45% identity, 99% coverage: 3:292/292 of query aligns to 3:293/293 of 5t25A
3s8hA Structure of dihydrodipicolinate synthase complexed with 3- hydroxypropanoic acid(hpa)at 2.70 a resolution
51% identity, 99% coverage: 5:292/292 of query aligns to 4:291/292 of 3s8hA
3puoA Crystal structure of dihydrodipicolinate synthase from pseudomonas aeruginosa(psdhdps)complexed with l-lysine at 2.65a resolution (see paper)
51% identity, 99% coverage: 5:292/292 of query aligns to 4:291/292 of 3puoA
>8499797 FitnessBrowser__Miya:8499797
MQFQGAFTALVTPFRNGEVDEERYRALVEWQIEQGINGLVPCGTTGESATLTHQEHKDVI
RICVEQVKGRVPVLAGAGSNNTREAVELTRYAKQAGADGALLITPYYNKPTQEGLYQHFK
AIAAEVPMPFIVYNVPSRTGTNLCPETLARMKRDIPEVIGVKEATGNLIQVSEIIEYCGA
DFQVLSGDDFTVLPLLAVGGCGVISVSSNVVPAKMSELCRAFFEGDLATARRVHYEIASI
NRAMFLETNPIPVKTALSMMGRIELELRLPMVPLQPANQSRLRDILSAAGIV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory