Comparing 8499807 FitnessBrowser__Miya:8499807 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 14 hits to proteins with known functional sites (download)
5vyeB Crystal structure of l-threonine aldolase from pseudomonas putida
45% identity, 99% coverage: 4:340/341 of query aligns to 4:341/344 of 5vyeB
O50584 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Pseudomonas sp. (strain NCIMB 10558) (see paper)
43% identity, 99% coverage: 4:340/341 of query aligns to 6:343/346 of O50584
1v72A Crystal structure of phenylserine aldolase from pseudomonas putida
43% identity, 98% coverage: 6:338/341 of query aligns to 7:342/345 of 1v72A
1jg8D Crystal structure of threonine aldolase (low-specificity)
27% identity, 59% coverage: 8:209/341 of query aligns to 7:196/344 of 1jg8D
Sites not aligning to the query:
1lw5B X-ray structure of l-threonine aldolase (low-specificity) in complex with glycine (see paper)
27% identity, 59% coverage: 8:209/341 of query aligns to 6:195/343 of 1lw5B
Sites not aligning to the query:
1lw4B X-ray structure of l-threonine aldolase (low-specificity) in complex with l-allo-threonine (see paper)
27% identity, 59% coverage: 8:209/341 of query aligns to 6:195/343 of 1lw4B
Sites not aligning to the query:
O07051 L-allo-threonine aldolase; L-allo-TA; L-allo-threonine acetaldehyde-lyase; EC 4.1.2.49 from Aeromonas jandaei (see paper)
23% identity, 89% coverage: 33:336/341 of query aligns to 32:331/338 of O07051
3wgcB Aeromonas jandaei l-allo-threonine aldolase h128y/s292r double mutant (see paper)
23% identity, 89% coverage: 33:336/341 of query aligns to 31:328/333 of 3wgcB
Sites not aligning to the query:
3wgbD Crystal structure of aeromonas jandaei l-allo-threonine aldolase (see paper)
28% identity, 44% coverage: 33:181/341 of query aligns to 30:174/324 of 3wgbD
Sites not aligning to the query:
3wlxA Crystal structure of low-specificity l-threonine aldolase from escherichia coli
22% identity, 88% coverage: 33:332/341 of query aligns to 30:322/331 of 3wlxA
Sites not aligning to the query:
4lnmA Structure of escherichia coli threonine aldolase in complex with serine (see paper)
24% identity, 52% coverage: 33:209/341 of query aligns to 30:207/331 of 4lnmA
Sites not aligning to the query:
4rjyA Crystal structure of e. Coli l-threonine aldolase in complex with a non-covalently uncleaved bound l-serine substrate (see paper)
24% identity, 52% coverage: 33:209/341 of query aligns to 30:207/332 of 4rjyA
4lnlA Structure of escherichia coli threonine aldolase in complex with allo- thr (see paper)
24% identity, 52% coverage: 33:209/341 of query aligns to 30:207/332 of 4lnlA
Sites not aligning to the query:
4lnjA Structure of escherichia coli threonine aldolase in unliganded form (see paper)
24% identity, 52% coverage: 33:209/341 of query aligns to 30:207/332 of 4lnjA
Sites not aligning to the query:
>8499807 FitnessBrowser__Miya:8499807
MSLKSFASDNTSGVHPRILAAMERANAGHARPYGQDPYTEQAKEVFARHFGPDIDMYFVF
LGTAANVLGLRAVTRPWHSVVCADVAHINVDECGAPESVTGSKLQVIPSHDGRIRVMDVV
PLLHMIGNFHHSQPRVISITQSTELGTVYSPAQIRALADFAHANGMLLHMDGARLANAAA
ALDVSLAALTRDAGVDVLSFGGTKNGMMFGEAVIFFNPELSREFNFIRKQGMQLISKMRF
IAAQFMEMLNDGLWLENARNANAMARLMADSLRGLPHVTITRPVEANAVFARLSPEHIAR
LQQDFYFYEWDPVLHEVRWMTSFDTTEEDVREFTDAVKALG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory