Comparing 8500980 FitnessBrowser__Miya:8500980 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
7npjB Crystal structure of mycobacterium tuberculosis argc in complex with 6-phenoxy-3-pyridinamine
39% identity, 99% coverage: 5:350/350 of query aligns to 3:344/344 of 7npjB
7nphC Crystal structure of mycobacterium tuberculosis argc in complex with 5-methoxy-1,3-benzoxazole-2-carboxylic acid
39% identity, 99% coverage: 5:350/350 of query aligns to 3:344/344 of 7nphC
7notA Crystal structure of mycobacterium tuberculosis argc in complex with nicotinamide adenine dinucleotide phosphate (NADP+) and 5-methoxy-3- indoleacetic acid
39% identity, 99% coverage: 5:350/350 of query aligns to 3:344/344 of 7notA
7nnrA Crystal structure of mycobacterium tuberculosis argc in complex with xanthene-9-carboxylic acid
39% identity, 99% coverage: 5:350/350 of query aligns to 3:344/344 of 7nnrA
2i3gA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (rv1652) from mycobacterium tuberculosis in complex with NADP+. (see paper)
39% identity, 99% coverage: 5:350/350 of query aligns to 6:347/347 of 2i3gA
2ozpA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (ttha1904) from thermus thermophilus
34% identity, 98% coverage: 8:350/350 of query aligns to 6:342/342 of 2ozpA
O50146 [LysW]-L-2-aminoadipate 6-phosphate reductase; EC 1.2.1.103 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
34% identity, 98% coverage: 8:350/350 of query aligns to 8:344/344 of O50146
5einA Crystal structure of c148a mutant of lysy from thermus thermophilus in complex with NADP+ and lysw-gamma-aminoadipic acid (see paper)
33% identity, 98% coverage: 8:350/350 of query aligns to 8:344/344 of 5einA
4dpmA Structure of malonyl-coenzyme a reductase from crenarchaeota in complex with coa (see paper)
26% identity, 53% coverage: 4:189/350 of query aligns to 3:181/354 of 4dpmA
Sites not aligning to the query:
4dplA Structure of malonyl-coenzyme a reductase from crenarchaeota in complex with NADP (see paper)
26% identity, 53% coverage: 4:189/350 of query aligns to 3:181/354 of 4dplA
Sites not aligning to the query:
4dpkA Structure of malonyl-coenzyme a reductase from crenarchaeota (see paper)
26% identity, 53% coverage: 4:189/350 of query aligns to 3:181/354 of 4dpkA
Sites not aligning to the query:
P78780 Probable aspartate-semialdehyde dehydrogenase; ASA dehydrogenase; ASADH; Aspartate-beta-semialdehyde dehydrogenase; EC 1.2.1.11 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
25% identity, 73% coverage: 1:256/350 of query aligns to 1:257/357 of P78780
Sites not aligning to the query:
>8500980 FitnessBrowser__Miya:8500980
MTIIRAGLVGVTGYTGMELTRLLAGHPNMRLVRATSRTEAGRPLSDIYPFLRGLPGGNAV
MTAPDPDDLADNCDVAFLAVPHGAAMEMGATLRQRGLRVVDLSADFRLRDPDVYEAWYKV
PHTRRAELPQAVYGLPELYGDAVKKAGLVANPGCYPTATILGLYAALKHGLVETDGIVVD
AKSGATGAGRKAAVGTLFCEVSDTFRAYNIGKHRHTPEIEQELSAIAGTSMVVSFNPHLL
PINRGILATIYAKLAKPVSPQDVQAAFEQTWQGSRWVRVLPAGQLPETRHVRGTMFCDVG
VVTDQRTNRLVILSAIDNLCRGASGQAVANANLMFGLPVETGLMLAPLMP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory