Comparing 8501128 FitnessBrowser__Miya:8501128 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 9 hits to proteins with known functional sites (download)
Q8ZND6 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.222; EC 2.3.1.8 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
37% identity, 100% coverage: 1:701/704 of query aligns to 1:713/714 of Q8ZND6
6ioxA Crystal structure of porphyromonas gingivalis phosphotransacetylase in complex with acetyl-coa (see paper)
50% identity, 46% coverage: 381:701/704 of query aligns to 10:338/339 of 6ioxA
1xcoD Crystal structure of a phosphotransacetylase from bacillus subtilis in complex with acetylphosphate (see paper)
49% identity, 45% coverage: 384:697/704 of query aligns to 12:324/325 of 1xcoD
P38503 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.8 from Methanosarcina thermophila (see 2 papers)
43% identity, 46% coverage: 376:700/704 of query aligns to 2:331/333 of P38503
Sites not aligning to the query:
2af3C Phosphotransacetylase from methanosarcina thermophila soaked with coenzyme a (see paper)
43% identity, 46% coverage: 376:700/704 of query aligns to 1:330/332 of 2af3C
6zngF Maeb full-length acetyl-coa bound state (see paper)
39% identity, 46% coverage: 377:698/704 of query aligns to 417:744/753 of 6zngF
Sites not aligning to the query:
P76558 NADP-dependent malic enzyme; NADP-ME; EC 1.1.1.40 from Escherichia coli (strain K12) (see paper)
31% identity, 47% coverage: 372:700/704 of query aligns to 419:757/759 of P76558
Sites not aligning to the query:
3uf6A The crystal structure of a possible phosphate acetyl/butaryl transferase (from listeria monocytogenes egd-e) in complex with cod (3'-dephosphocoenzyme a)
27% identity, 29% coverage: 475:679/704 of query aligns to 64:266/285 of 3uf6A
3u9eB The crystal structure of a possible phosphate acetyl/butaryl transferase (from listeria monocytogenes egd-e) in complex with coa.
27% identity, 29% coverage: 475:679/704 of query aligns to 66:268/288 of 3u9eB
Sites not aligning to the query:
>8501128 FitnessBrowser__Miya:8501128
MANNLYITATESKSGKSAVVLGMMQLLLRDIRKVAFFRPIINRPVTDAVDHDTNLILTHF
NLDIPVADTYAYSLQDARELINNGQHATLLENILKKYKQLEDSYDFVLCEGTDFLGKDAA
FEFDLNADIAANLGCPVMVVANGQQKTAHEIVASTQLTIDLLDEKGLDIVAAVINRASVT
DAERDVVISSLECKVNCSNPLAVYVVPEEPTLGKPTMGDVKKWLNAQVLYGHGRMDTLVD
DYVIAAMQIGNFLDYVTPGCLVITPGDRSDIILTGLATRLSGAYPDISGMLLTGGIQPAP
NVHRLIEGWTGVPIPILSVKDHTYKTIQTLNELYGKIEPDNERKINTALGLFERSVDSQE
LGRRLINRKSSRITPMMFEFNLIERAKQNRMRIVLPEGVEERILRAADILARREVADIIL
LGDADKVGAKVSELGIALDGVQIIQPNLSPKFEEYAQAYFELRKHKGVSIERARDTMNDV
TYFGTMMVHKGDAEGMVSGSINTTAHTIRPAFEFIKTKPGFSIVSSVFLMCLKDRVLAFG
DCAVNPNPTAEQLAEIAINSAHTARIFGIEPRVAMLSYSTGSSGKGADVEKVIEATRIAK
ERAPELLLEGPLQYDAAIDMDVARTKLPGSQVAGQATVFIFPDLNTGNNTYKAVQRAAGA
VAIGPVLQGLNKPVNDLSRGCTVPDIVNTVAITAIQAQAEKGLI
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory